Motif ID: Arnt2

Z-value: 0.358


Transcription factors associated with Arnt2:

Gene SymbolEntrez IDGene Name
Arnt2 ENSMUSG00000015709.8 Arnt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arnt2mm10_v2_chr7_-_84409959_844100020.335.6e-03Click!


Activity profile for motif Arnt2.

activity profile for motif Arnt2


Sorted Z-values histogram for motif Arnt2

Sorted Z-values for motif Arnt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_101496648 4.700 ENSMUST00000106930.1
ENSMUST00000154120.1
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr19_-_5098418 3.058 ENSMUST00000025805.6
 Cnih2
cornichon homolog 2 (Drosophila)
chr17_-_46890405 2.488 ENSMUST00000086675.3
 A330017A19Rik
RIKEN cDNA A330017A19 gene
chr2_-_54085542 2.419 ENSMUST00000100089.2
 Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr7_-_45370559 1.986 ENSMUST00000003971.7
 Lin7b
lin-7 homolog B (C. elegans)
chr7_+_130865756 1.967 ENSMUST00000120441.1
 Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_-_33371486 1.716 ENSMUST00000113165.1
 Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr7_+_130865835 1.618 ENSMUST00000075181.4
ENSMUST00000048180.5
 Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr2_-_33371400 1.597 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
 Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr1_-_52817643 1.517 ENSMUST00000027271.2
 Inpp1
inositol polyphosphate-1-phosphatase
chr1_+_59912972 1.384 ENSMUST00000036540.5
 Fam117b
family with sequence similarity 117, member B
chr14_-_63543931 1.341 ENSMUST00000058679.5
 Mtmr9
myotubularin related protein 9
chr1_-_52817503 1.232 ENSMUST00000162576.1
 Inpp1
inositol polyphosphate-1-phosphatase
chr4_-_123116686 1.167 ENSMUST00000166337.1
 Gm17244
predicted gene, 17244
chr13_+_118714678 1.067 ENSMUST00000022246.8
 Fgf10
fibroblast growth factor 10
chr1_-_58973421 1.045 ENSMUST00000173590.1
ENSMUST00000027186.5
 Trak2

trafficking protein, kinesin binding 2

chr12_-_59011996 1.040 ENSMUST00000021375.5
 Sec23a
SEC23A (S. cerevisiae)
chr1_+_58973521 0.994 ENSMUST00000114296.1
ENSMUST00000027185.4
 Stradb

STE20-related kinase adaptor beta

chr8_+_83900706 0.954 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
 Lphn1


latrophilin 1


chr1_-_16619245 0.901 ENSMUST00000182984.1
ENSMUST00000182554.1
 Ube2w

ubiquitin-conjugating enzyme E2W (putative)

chr1_+_87327008 0.899 ENSMUST00000172794.1
ENSMUST00000164992.2
 Gigyf2

GRB10 interacting GYF protein 2

chr13_+_13590402 0.867 ENSMUST00000110559.1
 Lyst
lysosomal trafficking regulator
chr17_-_26508463 0.855 ENSMUST00000025025.6
 Dusp1
dual specificity phosphatase 1
chr17_+_46890621 0.756 ENSMUST00000040434.7
 Tbcc
tubulin-specific chaperone C
chr1_+_87327044 0.677 ENSMUST00000173173.1
 Gigyf2
GRB10 interacting GYF protein 2
chr18_+_31634374 0.581 ENSMUST00000025109.7
 Sap130
Sin3A associated protein
chr1_+_87326997 0.560 ENSMUST00000027475.8
 Gigyf2
GRB10 interacting GYF protein 2
chr18_+_31634368 0.557 ENSMUST00000178164.1
 Sap130
Sin3A associated protein
chr11_+_107547925 0.520 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
 Helz


helicase with zinc finger domain


chr5_-_115300957 0.469 ENSMUST00000009157.3
 Dynll1
dynein light chain LC8-type 1
chr6_+_4601124 0.452 ENSMUST00000181734.1
ENSMUST00000141359.1
 Casd1

CAS1 domain containing 1

chr7_-_44869788 0.414 ENSMUST00000046575.9
 Ptov1
prostate tumor over expressed gene 1
chr5_-_115300912 0.406 ENSMUST00000112090.1
 Dynll1
dynein light chain LC8-type 1
chr2_+_119208975 0.183 ENSMUST00000102519.4
 Zfyve19
zinc finger, FYVE domain containing 19
chr7_+_19076242 0.167 ENSMUST00000032570.7
ENSMUST00000108479.1
 Dmwd

dystrophia myotonica-containing WD repeat motif

chr3_+_69721985 0.144 ENSMUST00000029358.8
 Nmd3
NMD3 homolog (S. cerevisiae)
chr10_-_63421739 0.071 ENSMUST00000054760.4
 Gm7075
predicted gene 7075
chr4_-_48279544 0.059 ENSMUST00000030028.4
 Erp44
endoplasmic reticulum protein 44
chr2_+_79255500 0.048 ENSMUST00000099972.4
 Itga4
integrin alpha 4
chr18_-_10030017 0.008 ENSMUST00000116669.1
ENSMUST00000092096.6
 Usp14

ubiquitin specific peptidase 14

chr4_-_41275091 0.004 ENSMUST00000030143.6
ENSMUST00000108068.1
 Ubap2

ubiquitin-associated protein 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.7 GO:0072318 clathrin coat disassembly(GO:0072318)
0.7 3.3 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.6 3.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.4 2.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.4 1.1 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.3 0.9 GO:0033364 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mast cell secretory granule organization(GO:0033364)
0.2 3.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 2.7 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1 2.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.2 GO:0009838 abscission(GO:0009838)
0.1 0.9 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 1.0 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.9 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 1.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 2.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.0 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 1.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 3.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.1 GO:0030914 STAGA complex(GO:0030914)
0.0 3.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.6 3.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 3.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.0 5.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 2.0 GO:0030165 PDZ domain binding(GO:0030165)