Motif ID: Atf6

Z-value: 1.510


Transcription factors associated with Atf6:

Gene SymbolEntrez IDGene Name
Atf6 ENSMUSG00000026663.6 Atf6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf6mm10_v2_chr1_-_170867761_170867784-0.056.9e-01Click!


Activity profile for motif Atf6.

activity profile for motif Atf6


Sorted Z-values histogram for motif Atf6

Sorted Z-values for motif Atf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_123267445 19.139 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr16_-_23988852 17.337 ENSMUST00000023151.5
 Bcl6
B cell leukemia/lymphoma 6
chr8_-_70487314 15.296 ENSMUST00000045286.7
 Tmem59l
transmembrane protein 59-like
chr7_+_126950518 12.975 ENSMUST00000106335.1
ENSMUST00000146017.1
 Sez6l2

seizure related 6 homolog like 2

chr5_+_134986191 12.922 ENSMUST00000094245.2
 Cldn3
claudin 3
chr12_+_82616885 12.826 ENSMUST00000161801.1
 Rgs6
regulator of G-protein signaling 6
chr5_-_136170634 12.494 ENSMUST00000041048.1
 Orai2
ORAI calcium release-activated calcium modulator 2
chr7_+_126950687 11.993 ENSMUST00000106333.1
 Sez6l2
seizure related 6 homolog like 2
chr7_+_126950837 11.857 ENSMUST00000106332.1
 Sez6l2
seizure related 6 homolog like 2
chr10_+_29211637 11.800 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr18_-_31447383 11.484 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr6_-_136173492 10.716 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chrX_+_41401128 9.544 ENSMUST00000115103.2
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr6_+_77242644 9.444 ENSMUST00000159616.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_77242715 9.364 ENSMUST00000161677.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr15_+_77084367 9.211 ENSMUST00000181870.1
 1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr6_-_8778439 8.410 ENSMUST00000115520.1
ENSMUST00000038403.5
ENSMUST00000115518.1
 Ica1


islet cell autoantigen 1


chr6_-_124464772 8.400 ENSMUST00000008297.4
 Clstn3
calsyntenin 3
chr10_-_18743691 8.255 ENSMUST00000019999.5
 D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr2_+_155276297 8.156 ENSMUST00000029128.3
 Map1lc3a
microtubule-associated protein 1 light chain 3 alpha

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 178 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 36.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.9 22.0 GO:0002091 negative regulation of receptor internalization(GO:0002091)
1.3 19.4 GO:0002115 store-operated calcium entry(GO:0002115)
5.8 17.3 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.8 16.3 GO:0090166 Golgi disassembly(GO:0090166)
0.6 15.6 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
1.3 14.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.8 13.9 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.2 13.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
1.6 12.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.9 12.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 11.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
1.4 11.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.2 11.1 GO:0071569 protein ufmylation(GO:0071569)
1.8 10.5 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
1.1 9.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.7 9.8 GO:0045176 apical protein localization(GO:0045176)
0.1 9.3 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.2 8.7 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.4 8.4 GO:0060416 response to growth hormone(GO:0060416)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 34.2 GO:0030426 growth cone(GO:0030426)
0.1 28.5 GO:0043025 neuronal cell body(GO:0043025)
0.5 26.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.8 20.3 GO:0043083 synaptic cleft(GO:0043083)
0.5 19.7 GO:0043034 costamere(GO:0043034)
0.4 18.8 GO:0031201 SNARE complex(GO:0031201)
0.4 17.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 14.8 GO:0005657 replication fork(GO:0005657)
0.1 14.4 GO:0043209 myelin sheath(GO:0043209)
0.8 14.3 GO:0000421 autophagosome membrane(GO:0000421)
0.2 14.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 14.3 GO:0005874 microtubule(GO:0005874)
0.1 13.6 GO:0097060 synaptic membrane(GO:0097060)
0.6 12.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.4 10.0 GO:0005827 polar microtubule(GO:0005827)
0.6 8.6 GO:0031045 dense core granule(GO:0031045)
0.1 8.2 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 7.6 GO:0030315 T-tubule(GO:0030315)
0.3 6.8 GO:0005605 basal lamina(GO:0005605)
0.2 6.5 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 124 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 20.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 18.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
1.4 17.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
1.3 15.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 15.6 GO:0008270 zinc ion binding(GO:0008270)
0.5 14.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.9 14.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
3.0 11.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
1.4 11.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.7 11.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 11.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 10.8 GO:0005096 GTPase activator activity(GO:0005096)
1.1 10.7 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 10.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 10.3 GO:0005158 insulin receptor binding(GO:0005158)
0.3 9.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.4 9.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 8.3 GO:0017137 Rab GTPase binding(GO:0017137)
1.0 8.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 8.2 GO:0008565 protein transporter activity(GO:0008565)