Motif ID: Barhl2

Z-value: 1.036


Transcription factors associated with Barhl2:

Gene SymbolEntrez IDGene Name
Barhl2 ENSMUSG00000034384.10 Barhl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl2mm10_v2_chr5_-_106458440_106458470-0.458.1e-05Click!


Activity profile for motif Barhl2.

activity profile for motif Barhl2


Sorted Z-values histogram for motif Barhl2

Sorted Z-values for motif Barhl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_154960915 15.771 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr11_+_112782182 14.960 ENSMUST00000000579.2
 Sox9
SRY-box containing gene 9
chr18_-_80986578 14.681 ENSMUST00000057950.7
 Sall3
sal-like 3 (Drosophila)
chr5_+_110839973 14.482 ENSMUST00000066160.1
 Chek2
checkpoint kinase 2
chr16_-_22439719 13.361 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr2_+_163225363 11.239 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr17_-_49564262 10.379 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chrX_-_60893430 10.358 ENSMUST00000135107.2
 Sox3
SRY-box containing gene 3
chr18_+_61045139 10.332 ENSMUST00000025522.4
ENSMUST00000115274.1
 Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr3_-_27153844 10.310 ENSMUST00000176242.2
ENSMUST00000176780.1
 Ect2

ect2 oncogene

chr3_-_27153782 9.924 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
 Ect2


ect2 oncogene


chr2_+_59612034 9.703 ENSMUST00000112568.1
ENSMUST00000037526.4
 Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr3_-_27153861 9.681 ENSMUST00000108300.1
ENSMUST00000108298.2
 Ect2

ect2 oncogene

chr19_-_6969746 9.379 ENSMUST00000025912.8
 Plcb3
phospholipase C, beta 3
chr18_-_78206408 9.166 ENSMUST00000163367.1
 Slc14a2
solute carrier family 14 (urea transporter), member 2
chrX_+_71663665 9.023 ENSMUST00000070449.5
 Gpr50
G-protein-coupled receptor 50
chr5_-_28467093 8.530 ENSMUST00000002708.3
 Shh
sonic hedgehog
chr19_+_25406661 8.249 ENSMUST00000146647.1
 Kank1
KN motif and ankyrin repeat domains 1
chr2_+_118814237 8.223 ENSMUST00000028803.7
ENSMUST00000126045.1
 Knstrn

kinetochore-localized astrin/SPAG5 binding

chr5_-_37824580 8.204 ENSMUST00000063116.9
 Msx1
msh homeobox 1
chr16_-_22439570 8.078 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr17_-_25727364 7.299 ENSMUST00000170070.1
ENSMUST00000048054.7
 Chtf18

CTF18, chromosome transmission fidelity factor 18

chr6_-_95718800 7.193 ENSMUST00000079847.5
 Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr3_-_154328634 7.043 ENSMUST00000167744.1
 Lhx8
LIM homeobox protein 8
chr7_+_24370255 6.773 ENSMUST00000171904.1
 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr7_+_79660196 6.593 ENSMUST00000035977.7
 Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr2_-_127133909 6.588 ENSMUST00000110387.3
 Ncaph
non-SMC condensin I complex, subunit H
chr8_+_57511833 6.486 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr5_+_33658123 6.464 ENSMUST00000074849.6
ENSMUST00000079534.4
 Tacc3

transforming, acidic coiled-coil containing protein 3

chr15_+_99074968 6.323 ENSMUST00000039665.6
 Troap
trophinin associated protein
chr7_+_127841752 6.115 ENSMUST00000033075.7
 Stx4a
syntaxin 4A (placental)
chr4_-_58553553 6.038 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
 Lpar1


lysophosphatidic acid receptor 1


chr4_+_132768325 5.881 ENSMUST00000102561.4
 Rpa2
replication protein A2
chr6_+_63255971 5.724 ENSMUST00000159561.1
ENSMUST00000095852.3
 Grid2

glutamate receptor, ionotropic, delta 2

chr17_+_35439155 5.630 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
 H2-Q7



histocompatibility 2, Q region locus 7



chr2_-_58052832 5.498 ENSMUST00000090940.5
 Ermn
ermin, ERM-like protein
chr4_-_9643638 5.428 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
 Asph




aspartate-beta-hydroxylase




chr7_+_127841817 5.359 ENSMUST00000121705.1
 Stx4a
syntaxin 4A (placental)
chr18_+_4993795 5.160 ENSMUST00000153016.1
 Svil
supervillin
chr12_+_78748947 5.007 ENSMUST00000082024.5
 Mpp5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr1_-_163725123 4.809 ENSMUST00000159679.1
 Mettl11b
methyltransferase like 11B
chr10_+_73821857 4.806 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
 Pcdh15



















protocadherin 15



















chr7_+_27486910 4.797 ENSMUST00000008528.7
 Sertad1
SERTA domain containing 1
chr1_-_93343482 4.675 ENSMUST00000128253.1
 Pask
PAS domain containing serine/threonine kinase
chr10_+_58394381 4.670 ENSMUST00000105468.1
 Lims1
LIM and senescent cell antigen-like domains 1
chr13_-_47106176 4.342 ENSMUST00000021807.6
ENSMUST00000135278.1
 Dek

DEK oncogene (DNA binding)

chr11_+_85832551 3.951 ENSMUST00000000095.6
 Tbx2
T-box 2
chr11_+_78261717 3.892 ENSMUST00000010421.6
 2610507B11Rik
RIKEN cDNA 2610507B11 gene
chr8_+_94214567 3.722 ENSMUST00000079961.6
 Nup93
nucleoporin 93
chr6_-_146502099 3.485 ENSMUST00000053273.8
 Itpr2
inositol 1,4,5-triphosphate receptor 2
chr10_+_58394361 3.293 ENSMUST00000020077.4
 Lims1
LIM and senescent cell antigen-like domains 1
chr1_+_153899937 3.265 ENSMUST00000086199.5
 Glul
glutamate-ammonia ligase (glutamine synthetase)
chr2_+_31640037 3.177 ENSMUST00000113470.2
 Prdm12
PR domain containing 12
chr7_+_128246812 3.134 ENSMUST00000164710.1
ENSMUST00000070656.5
 Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr6_-_34317442 3.133 ENSMUST00000154655.1
ENSMUST00000102980.4
 Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr5_+_65131184 3.133 ENSMUST00000031089.5
ENSMUST00000101191.3
 Klhl5

kelch-like 5

chr7_+_128246953 3.080 ENSMUST00000167965.1
 Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr19_-_29648355 3.065 ENSMUST00000159692.1
 Ermp1
endoplasmic reticulum metallopeptidase 1
chr12_-_34528844 2.991 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9
chr2_+_181319714 2.691 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
 Rtel1




regulator of telomere elongation helicase 1




chr16_+_10835046 2.399 ENSMUST00000037913.8
 Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr2_+_181319806 2.347 ENSMUST00000153112.1
 Rtel1
regulator of telomere elongation helicase 1
chr5_-_134946917 2.299 ENSMUST00000051401.2
 Cldn4
claudin 4
chr1_+_165788681 2.272 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
 Cd247



CD247 antigen



chr6_+_125552948 2.251 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr1_+_105990652 2.239 ENSMUST00000118196.1
 Zcchc2
zinc finger, CCHC domain containing 2
chr7_+_43444104 2.237 ENSMUST00000004729.3
 Etfb
electron transferring flavoprotein, beta polypeptide
chr11_-_20332689 2.228 ENSMUST00000109594.1
 Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chrX_+_95711641 2.056 ENSMUST00000150123.1
 Zc3h12b
zinc finger CCCH-type containing 12B
chr11_-_20332654 1.974 ENSMUST00000004634.6
 Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_-_153900198 1.874 ENSMUST00000123490.1
 5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr6_-_47813512 1.829 ENSMUST00000077290.7
 Pdia4
protein disulfide isomerase associated 4
chr18_-_84086379 1.742 ENSMUST00000060303.8
 Tshz1
teashirt zinc finger family member 1
chr9_-_13826946 1.662 ENSMUST00000147115.1
 Cep57
centrosomal protein 57
chr7_+_127211608 1.583 ENSMUST00000032910.6
 Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr17_+_79614900 1.559 ENSMUST00000040368.2
 Rmdn2
regulator of microtubule dynamics 2
chr1_+_105990384 1.490 ENSMUST00000119166.1
 Zcchc2
zinc finger, CCHC domain containing 2
chr3_-_110143937 1.438 ENSMUST00000051253.3
 Ntng1
netrin G1
chr7_+_3629985 1.432 ENSMUST00000008517.6
ENSMUST00000179769.1
 Prpf31

PRP31 pre-mRNA processing factor 31 homolog (yeast)

chr2_-_84715160 1.396 ENSMUST00000035840.5
 Zdhhc5
zinc finger, DHHC domain containing 5
chr1_+_165788746 1.387 ENSMUST00000161559.2
 Cd247
CD247 antigen
chrX_+_82948861 1.345 ENSMUST00000114000.1
 Dmd
dystrophin, muscular dystrophy
chr3_-_49757257 1.335 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr6_-_8259098 1.203 ENSMUST00000012627.4
 Rpa3
replication protein A3
chr10_+_88459569 1.186 ENSMUST00000020252.3
ENSMUST00000125612.1
 Sycp3

synaptonemal complex protein 3

chr17_-_34287770 1.176 ENSMUST00000174751.1
ENSMUST00000040655.6
 H2-Aa

histocompatibility 2, class II antigen A, alpha

chr3_+_96629919 1.137 ENSMUST00000048915.6
 Rbm8a
RNA binding motif protein 8a
chr10_+_80826656 1.057 ENSMUST00000060987.8
ENSMUST00000177850.1
ENSMUST00000180036.1
ENSMUST00000179172.1
 Oaz1



ornithine decarboxylase antizyme 1



chr2_-_18048347 1.051 ENSMUST00000066885.5
 Skida1
SKI/DACH domain containing 1
chr8_-_90908415 1.051 ENSMUST00000098517.1
 Gm6658
predicted gene 6658
chr4_-_41275091 1.042 ENSMUST00000030143.6
ENSMUST00000108068.1
 Ubap2

ubiquitin-associated protein 2

chrX_+_169879596 0.948 ENSMUST00000112105.1
ENSMUST00000078947.5
 Mid1

midline 1

chr19_-_12796108 0.853 ENSMUST00000038627.8
 Zfp91
zinc finger protein 91
chr18_+_61639542 0.833 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr2_-_129699833 0.803 ENSMUST00000028883.5
 Pdyn
prodynorphin
chr11_-_120572822 0.798 ENSMUST00000168360.1
 P4hb
prolyl 4-hydroxylase, beta polypeptide
chr11_+_62820469 0.787 ENSMUST00000108703.1
 Trim16
tripartite motif-containing 16
chr1_+_91250482 0.785 ENSMUST00000171112.1
 Ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr5_-_110839757 0.780 ENSMUST00000056937.5
 Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr10_-_99759658 0.639 ENSMUST00000056085.4
 Csl
citrate synthase like
chrX_-_59166080 0.637 ENSMUST00000119306.1
 Fgf13
fibroblast growth factor 13
chr1_+_91250311 0.611 ENSMUST00000059743.5
ENSMUST00000178627.1
ENSMUST00000171165.1
 Ube2f


ubiquitin-conjugating enzyme E2F (putative)


chr15_-_33405976 0.547 ENSMUST00000079057.6
 1700084J12Rik
RIKEN cDNA 1700084J12 gene
chr5_+_135168382 0.517 ENSMUST00000111187.3
ENSMUST00000111188.1
 Bcl7b

B cell CLL/lymphoma 7B

chr7_-_19715395 0.484 ENSMUST00000032555.9
ENSMUST00000093552.5
 Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr18_+_34736359 0.431 ENSMUST00000105038.2
 Gm3550
predicted gene 3550
chr7_+_100495987 0.402 ENSMUST00000133044.1
 Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr2_-_120539852 0.359 ENSMUST00000171215.1
 Zfp106
zinc finger protein 106
chr7_-_90475971 0.353 ENSMUST00000032843.7
 Tmem126b
transmembrane protein 126B
chr8_-_107439585 0.318 ENSMUST00000077208.4
 Rps26-ps1
ribosomal protein S26, pseudogene 1
chr7_+_101969796 0.273 ENSMUST00000084852.5
 Numa1
nuclear mitotic apparatus protein 1
chr14_-_99099701 0.236 ENSMUST00000042471.9
 Dis3
DIS3 mitotic control homolog (S. cerevisiae)
chr4_-_43000451 0.150 ENSMUST00000030164.7
 Vcp
valosin containing protein
chr5_+_145204523 0.121 ENSMUST00000085671.3
ENSMUST00000031601.7
 Zkscan5

zinc finger with KRAB and SCAN domains 5

chr2_+_9882622 0.110 ENSMUST00000114919.1
 4930412O13Rik
RIKEN cDNA 4930412O13 gene
chr5_+_135168283 0.099 ENSMUST00000031692.5
 Bcl7b
B cell CLL/lymphoma 7B
chr1_-_171287931 0.046 ENSMUST00000111306.3
ENSMUST00000065941.5
 Usp21

ubiquitin specific peptidase 21


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.0 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
4.3 21.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
3.9 15.8 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
3.8 11.5 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
3.6 14.5 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
3.4 10.3 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
2.8 8.5 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
2.7 8.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
2.7 8.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
2.1 38.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.0 8.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
1.8 5.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.5 6.0 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.4 6.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.3 4.0 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
1.3 9.2 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
1.3 5.0 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
1.1 14.7 GO:0021891 olfactory bulb interneuron development(GO:0021891)
1.1 3.3 GO:0019676 ammonia assimilation cycle(GO:0019676)
1.1 4.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
1.0 3.1 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.9 6.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.9 7.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.9 6.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.8 6.6 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174) mitotic DNA replication checkpoint(GO:0033314)
0.8 7.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.6 10.4 GO:0007530 sex determination(GO:0007530)
0.6 3.2 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.6 1.8 GO:1903334 positive regulation of protein folding(GO:1903334)
0.6 4.2 GO:0015808 L-alanine transport(GO:0015808)
0.6 1.7 GO:0060023 soft palate development(GO:0060023)
0.5 9.7 GO:0097062 dendritic spine maintenance(GO:0097062)
0.5 4.8 GO:0050957 equilibrioception(GO:0050957)
0.5 4.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.5 6.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.5 3.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.4 1.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 5.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 6.5 GO:0030953 astral microtubule organization(GO:0030953)
0.4 1.2 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.3 3.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.3 5.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.3 5.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 2.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.3 3.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.3 1.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.3 9.4 GO:0009395 phospholipid catabolic process(GO:0009395)
0.2 7.0 GO:0021884 forebrain neuron development(GO:0021884)
0.1 5.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.7 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 1.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 3.7 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 0.8 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 2.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.6 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 9.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.4 GO:0045116 protein neddylation(GO:0045116)
0.1 1.4 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 1.2 GO:0006298 mismatch repair(GO:0006298)
0.1 3.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 1.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 3.1 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 2.3 GO:0001889 liver development(GO:0001889)
0.0 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 5.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 4.8 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 5.1 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 8.1 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 29.9 GO:0097149 centralspindlin complex(GO:0097149)
2.1 16.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
1.2 7.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
1.2 7.0 GO:0001674 female germ cell nucleus(GO:0001674)
1.1 6.6 GO:0000796 condensin complex(GO:0000796)
1.1 5.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.9 3.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.9 7.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.8 3.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.7 5.5 GO:0033269 internode region of axon(GO:0033269)
0.6 2.2 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.5 7.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 2.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.4 5.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 1.2 GO:0000802 transverse filament(GO:0000802)
0.2 8.2 GO:0035371 microtubule plus-end(GO:0035371)
0.2 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 3.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 3.3 GO:0097386 glial cell projection(GO:0097386)
0.2 6.5 GO:0043034 costamere(GO:0043034)
0.2 1.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 15.3 GO:0016605 PML body(GO:0016605)
0.1 1.4 GO:0005687 U4 snRNP(GO:0005687)
0.1 4.8 GO:0032420 stereocilium(GO:0032420)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 8.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.3 GO:0000235 astral microtubule(GO:0000235)
0.1 10.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 16.4 GO:0016324 apical plasma membrane(GO:0016324)
0.1 9.4 GO:0042383 sarcolemma(GO:0042383)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 15.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 6.5 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 13.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 4.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 4.5 GO:0005813 centrosome(GO:0005813)
0.0 2.6 GO:0034399 nuclear periphery(GO:0034399)
0.0 4.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 5.2 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0008502 melatonin receptor activity(GO:0008502)
2.9 11.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
2.1 10.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
1.7 8.5 GO:0005113 patched binding(GO:0005113)
1.7 6.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.5 9.2 GO:0015265 urea channel activity(GO:0015265)
1.2 3.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.1 12.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
1.1 3.3 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
1.1 6.5 GO:0050786 RAGE receptor binding(GO:0050786)
1.0 6.0 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.8 6.2 GO:0048495 Roundabout binding(GO:0048495)
0.7 7.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.7 7.2 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.5 4.2 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.5 9.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 5.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 40.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.3 5.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 1.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 2.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 9.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 1.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.3 0.8 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 5.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 1.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 1.2 GO:0001515 opioid peptide activity(GO:0001515)
0.2 3.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 2.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 19.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 3.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 8.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 3.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 7.1 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 11.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 8.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 5.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 10.7 GO:0051015 actin filament binding(GO:0051015)
0.1 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 8.0 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 2.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 14.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 35.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 2.2 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.9 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 5.7 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.9 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 4.4 GO:0003682 chromatin binding(GO:0003682)
0.0 2.8 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 1.2 GO:0047485 protein N-terminus binding(GO:0047485)