Motif ID: Bcl6

Z-value: 0.682


Transcription factors associated with Bcl6:

Gene SymbolEntrez IDGene Name
Bcl6 ENSMUSG00000022508.5 Bcl6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6mm10_v2_chr16_-_23988852_239888520.621.2e-08Click!


Activity profile for motif Bcl6.

activity profile for motif Bcl6


Sorted Z-values histogram for motif Bcl6

Sorted Z-values for motif Bcl6



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 7.384 ENSMUST00000107377.3
 Tnc
tenascin C
chr3_-_80802789 5.398 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr3_-_152982240 5.301 ENSMUST00000044278.5
 St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr1_-_169747634 5.189 ENSMUST00000027991.5
ENSMUST00000111357.1
 Rgs4

regulator of G-protein signaling 4

chr11_+_101245996 4.525 ENSMUST00000129680.1
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr10_+_100015817 4.433 ENSMUST00000130190.1
ENSMUST00000020129.7
 Kitl

kit ligand

chr15_-_54919961 4.181 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
 Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chrX_-_61185558 3.239 ENSMUST00000166381.1
 Cdr1
cerebellar degeneration related antigen 1
chr15_-_8710409 3.238 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr10_+_58813359 3.226 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr15_-_8710734 3.225 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_+_37484955 3.210 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr15_-_54920115 3.182 ENSMUST00000171545.1
 Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr6_+_115134899 3.108 ENSMUST00000009538.5
ENSMUST00000169345.1
 Syn2

synapsin II

chr1_-_175491130 3.096 ENSMUST00000027812.5
 Rgs7
regulator of G protein signaling 7
chr4_+_144892813 3.093 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr9_+_20868628 2.868 ENSMUST00000043911.7
 A230050P20Rik
RIKEN cDNA A230050P20 gene
chr19_+_34217588 2.844 ENSMUST00000119603.1
 Stambpl1
STAM binding protein like 1
chr8_-_124569696 2.793 ENSMUST00000063278.6
 Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr9_+_50752758 2.777 ENSMUST00000034562.7
 Cryab
crystallin, alpha B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 7.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.1 7.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.7 7.2 GO:0042572 retinol metabolic process(GO:0042572)
1.6 6.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 5.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 5.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 5.0 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.5 4.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
1.1 4.4 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 4.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.4 3.4 GO:0032264 IMP salvage(GO:0032264)
0.8 3.3 GO:0042938 dipeptide transport(GO:0042938)
0.5 3.3 GO:1900451 rhythmic synaptic transmission(GO:0060024) terminal button organization(GO:0072553) positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of protein localization to synapse(GO:1902474) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 3.3 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 3.1 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.9 2.8 GO:0002034 ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) establishment of blood-nerve barrier(GO:0008065) regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963) response to muscle activity involved in regulation of muscle adaptation(GO:0014873) regulation of membrane hyperpolarization(GO:1902630)
0.5 2.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.7 2.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 2.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 2.3 GO:0006376 mRNA splice site selection(GO:0006376)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.5 8.2 GO:0005614 interstitial matrix(GO:0005614)
0.4 6.5 GO:0043205 fibril(GO:0043205)
0.3 5.4 GO:0032279 asymmetric synapse(GO:0032279)
0.2 5.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.5 GO:0072562 blood microparticle(GO:0072562)
0.0 3.3 GO:0043235 receptor complex(GO:0043235)
0.2 3.1 GO:0044292 dendrite terminus(GO:0044292)
0.1 3.1 GO:0031201 SNARE complex(GO:0031201)
0.9 2.8 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.6 GO:0031672 A band(GO:0031672)
0.0 2.3 GO:0005903 brush border(GO:0005903)
0.1 2.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.4 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)
0.1 1.6 GO:0005915 zonula adherens(GO:0005915)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 1.5 GO:0044316 cone cell pedicle(GO:0044316)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 7.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
1.2 7.4 GO:0045545 syndecan binding(GO:0045545)
1.0 7.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.3 6.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.9 5.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.8 5.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 5.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 4.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.7 4.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.5 3.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.7 3.3 GO:0042895 antibiotic transporter activity(GO:0042895)
0.5 3.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 3.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 3.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.2 3.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 3.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 2.8 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.2 2.8 GO:0048018 receptor agonist activity(GO:0048018)
0.7 2.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)