Motif ID: Bcl6b

Z-value: 0.473


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.301.2e-02Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_64046925 4.520 ENSMUST00000107377.3
 Tnc
tenascin C
chr16_-_74411292 4.468 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr16_-_74411776 3.891 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr9_+_40269430 3.024 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chr1_-_173942445 2.999 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr3_+_55242526 2.590 ENSMUST00000054237.7
ENSMUST00000167204.1
 Dclk1

doublecortin-like kinase 1

chr8_+_13907748 2.491 ENSMUST00000043520.3
 Fbxo25
F-box protein 25
chr19_-_5797410 2.370 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr10_-_95417099 2.294 ENSMUST00000135822.1
 Socs2
suppressor of cytokine signaling 2
chrX_+_151344171 2.111 ENSMUST00000073364.5
 Fam120c
family with sequence similarity 120, member C
chr2_-_65567465 2.065 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr13_-_98815408 2.042 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
 Fcho2



FCH domain only 2



chr2_-_65567505 1.977 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr10_-_95416850 1.904 ENSMUST00000020215.9
 Socs2
suppressor of cytokine signaling 2
chr2_+_119594288 1.798 ENSMUST00000147425.1
ENSMUST00000153581.1
 1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr3_-_96240317 1.630 ENSMUST00000078756.5
 Hist2h2aa2
histone cluster 2, H2aa2
chr10_+_57794335 1.609 ENSMUST00000151623.1
ENSMUST00000020022.7
 Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr6_+_149309391 1.523 ENSMUST00000130664.1
ENSMUST00000046689.6
 2810474O19Rik

RIKEN cDNA 2810474O19 gene

chr16_-_34262830 1.498 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr6_+_149309444 1.465 ENSMUST00000100765.4
 2810474O19Rik
RIKEN cDNA 2810474O19 gene
chr16_-_34263179 1.445 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr18_+_37320374 1.442 ENSMUST00000078271.2
 Pcdhb5
protocadherin beta 5
chr10_+_81633694 1.438 ENSMUST00000140345.1
ENSMUST00000126323.1
 Ankrd24

ankyrin repeat domain 24

chr11_+_70764209 1.285 ENSMUST00000060444.5
 Zfp3
zinc finger protein 3
chr5_-_123140135 1.274 ENSMUST00000160099.1
 AI480526
expressed sequence AI480526
chr5_-_150665560 1.257 ENSMUST00000118316.1
 N4bp2l2
NEDD4 binding protein 2-like 2
chr12_-_40134175 1.214 ENSMUST00000078481.7
ENSMUST00000002640.5
 Scin

scinderin

chr5_-_150665315 1.079 ENSMUST00000141857.1
 N4bp2l2
NEDD4 binding protein 2-like 2
chr12_-_98577940 1.078 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr8_+_12915879 1.062 ENSMUST00000110876.2
ENSMUST00000110879.2
 Mcf2l

mcf.2 transforming sequence-like

chr16_-_34262945 1.050 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr9_-_112232449 0.961 ENSMUST00000035085.5
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr2_-_180824596 0.884 ENSMUST00000148700.1
 Gm14340
predicted gene 14340
chr9_+_107296682 0.742 ENSMUST00000168260.1
 Cish
cytokine inducible SH2-containing protein
chr18_+_33794915 0.718 ENSMUST00000179138.1
 2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr3_+_95588960 0.656 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
 Golph3l


golgi phosphoprotein 3-like


chr7_+_43579577 0.628 ENSMUST00000058104.7
 Zfp719
zinc finger protein 719
chr9_+_107296843 0.628 ENSMUST00000167072.1
 Cish
cytokine inducible SH2-containing protein
chr18_+_42275353 0.535 ENSMUST00000046972.7
ENSMUST00000091920.5
 Rbm27

RNA binding motif protein 27

chr3_+_95588990 0.530 ENSMUST00000177399.1
 Golph3l
golgi phosphoprotein 3-like
chr3_+_95588928 0.508 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
 Golph3l


golgi phosphoprotein 3-like


chr11_+_95712673 0.457 ENSMUST00000107717.1
 Zfp652
zinc finger protein 652
chr8_+_25601591 0.420 ENSMUST00000155861.1
 Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr7_-_16221993 0.412 ENSMUST00000118795.1
ENSMUST00000119102.1
ENSMUST00000094816.2
ENSMUST00000163968.1
ENSMUST00000121123.1
 Dhx34




DEAH (Asp-Glu-Ala-His) box polypeptide 34




chr11_+_93098404 0.383 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
 Car10



carbonic anhydrase 10



chr1_+_82316452 0.355 ENSMUST00000027322.7
 Rhbdd1
rhomboid domain containing 1
chrX_+_153359613 0.352 ENSMUST00000039545.4
 Klf8
Kruppel-like factor 8
chr10_-_86705485 0.351 ENSMUST00000020238.7
 Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr2_+_175283298 0.328 ENSMUST00000098998.3
 Gm14440
predicted gene 14440
chr11_+_58432559 0.308 ENSMUST00000108825.1
 Gm12253
predicted gene 12253
chrX_+_74429671 0.247 ENSMUST00000114127.1
ENSMUST00000064407.3
ENSMUST00000156707.1
 Ikbkg


inhibitor of kappaB kinase gamma


chr8_+_27042555 0.169 ENSMUST00000033875.8
ENSMUST00000098851.4
 Prosc

proline synthetase co-transcribed

chr18_+_33794882 0.165 ENSMUST00000146010.2
 2410004N09Rik
RIKEN cDNA 2410004N09 gene
chrX_+_48623737 0.153 ENSMUST00000114936.1
 Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr17_-_45592569 0.152 ENSMUST00000163492.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr9_-_90255927 0.151 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr13_-_76018524 0.147 ENSMUST00000050997.1
ENSMUST00000179078.1
ENSMUST00000167271.1
 Rfesd


Rieske (Fe-S) domain containing


chr3_+_84925476 0.143 ENSMUST00000107675.1
 Fbxw7
F-box and WD-40 domain protein 7
chr4_+_3574872 0.141 ENSMUST00000052712.5
 Tgs1
trimethylguanosine synthase homolog (S. cerevisiae)
chr6_+_124916863 0.141 ENSMUST00000069553.2
 A230083G16Rik
RIKEN cDNA A230083G16 gene
chr1_+_191717834 0.110 ENSMUST00000110855.1
ENSMUST00000133076.1
 Lpgat1

lysophosphatidylglycerol acyltransferase 1

chr18_-_78123324 0.106 ENSMUST00000160292.1
ENSMUST00000091813.5
 Slc14a1

solute carrier family 14 (urea transporter), member 1

chr4_+_149485260 0.103 ENSMUST00000030842.7
 Lzic
leucine zipper and CTNNBIP1 domain containing
chr15_-_54919961 0.102 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
 Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr4_+_155562348 0.092 ENSMUST00000030939.7
 Nadk
NAD kinase
chr6_-_128355826 0.086 ENSMUST00000001562.6
 Tulp3
tubby-like protein 3
chr9_+_121938099 0.062 ENSMUST00000063103.4
 1700048O20Rik
RIKEN cDNA 1700048O20 gene
chr17_-_45592485 0.050 ENSMUST00000166119.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr7_+_119900099 0.026 ENSMUST00000106516.1
 Lyrm1
LYR motif containing 1
chr1_+_139454747 0.019 ENSMUST00000053364.8
ENSMUST00000097554.3
 Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr2_-_155729359 0.014 ENSMUST00000040833.4
 Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr6_+_106769120 0.007 ENSMUST00000113247.1
ENSMUST00000113249.1
ENSMUST00000057578.9
ENSMUST00000113248.1
 Trnt1



tRNA nucleotidyl transferase, CCA-adding, 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.1 4.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.8 4.0 GO:0046684 response to pyrethroid(GO:0046684)
0.8 2.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.6 2.4 GO:0035063 nuclear speck organization(GO:0035063)
0.5 4.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.4 3.0 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.2 1.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 4.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 1.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 3.0 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 2.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 2.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 1.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 1.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.0 1.7 GO:0007030 Golgi organization(GO:0007030)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 4.5 GO:0005614 interstitial matrix(GO:0005614)
0.3 8.4 GO:0030673 axolemma(GO:0030673)
0.1 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 2.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.3 GO:0016607 nuclear speck(GO:0016607)
0.0 5.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 8.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.9 4.5 GO:0045545 syndecan binding(GO:0045545)
0.8 4.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 3.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 4.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 1.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 2.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 2.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.0 4.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 3.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)