Motif ID: Bhlhe40

Z-value: 0.524


Transcription factors associated with Bhlhe40:

Gene SymbolEntrez IDGene Name
Bhlhe40 ENSMUSG00000030103.5 Bhlhe40

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe40mm10_v2_chr6_+_108660616_108660682-0.532.7e-06Click!


Activity profile for motif Bhlhe40.

activity profile for motif Bhlhe40


Sorted Z-values histogram for motif Bhlhe40

Sorted Z-values for motif Bhlhe40



Network of associatons between targets according to the STRING database.



First level regulatory network of Bhlhe40

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 99 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_121707189 2.901 ENSMUST00000065310.2
 1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr4_-_148038769 2.615 ENSMUST00000030879.5
ENSMUST00000137724.1
 Clcn6

chloride channel 6

chr4_+_148039097 2.200 ENSMUST00000141283.1
 Mthfr
5,10-methylenetetrahydrofolate reductase
chr11_+_97450136 2.034 ENSMUST00000107601.1
 Arhgap23
Rho GTPase activating protein 23
chr4_+_148039035 1.963 ENSMUST00000097788.4
 Mthfr
5,10-methylenetetrahydrofolate reductase
chr10_-_80139347 1.574 ENSMUST00000105369.1
 Dos
downstream of Stk11
chr3_-_10440054 1.551 ENSMUST00000099223.4
ENSMUST00000029047.6
 Snx16

sorting nexin 16

chr5_+_65199691 1.510 ENSMUST00000041892.8
 Wdr19
WD repeat domain 19
chr8_+_85037151 1.507 ENSMUST00000166592.1
 Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr1_+_5083105 1.498 ENSMUST00000044369.7
 Atp6v1h
ATPase, H+ transporting, lysosomal V1 subunit H
chr16_-_44139003 1.489 ENSMUST00000124102.1
 Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr5_-_123572976 1.470 ENSMUST00000031388.8
 Vps33a
vacuolar protein sorting 33A (yeast)
chrX_-_136203637 1.466 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
 Tceal5


transcription elongation factor A (SII)-like 5


chr8_+_85036906 1.419 ENSMUST00000093360.4
 Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr16_-_44139630 1.397 ENSMUST00000137557.1
ENSMUST00000147025.1
 Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr4_+_134468320 1.391 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
 Stmn1


stathmin 1


chrX_+_153832225 1.377 ENSMUST00000148708.1
ENSMUST00000123264.1
ENSMUST00000049999.8
 Spin2c


spindlin family, member 2C


chr16_+_8830093 1.354 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr16_-_92466081 1.309 ENSMUST00000060005.8
 Rcan1
regulator of calcineurin 1
chr1_-_75219245 1.259 ENSMUST00000079464.6
 Tuba4a
tubulin, alpha 4A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.4 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
1.0 4.2 GO:0070829 heterochromatin maintenance(GO:0070829)
0.3 2.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 2.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 2.3 GO:0097352 autophagosome maturation(GO:0097352)
0.1 1.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 1.6 GO:0097178 ruffle assembly(GO:0097178)
0.0 1.6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.4 1.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.1 1.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 1.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 0.9 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.9 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.8 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.8 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.8 GO:0009303 rRNA transcription(GO:0009303)
0.2 0.7 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.2 0.6 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.6 GO:0001675 acrosome assembly(GO:0001675)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 5.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 4.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.0 GO:0034399 nuclear periphery(GO:0034399)
0.3 1.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 1.5 GO:0033263 CORVET complex(GO:0033263)
0.2 1.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 0.8 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.7 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.6 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.5 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.4 4.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 2.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 2.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.6 GO:0005123 death receptor binding(GO:0005123)
0.2 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.1 1.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.1 GO:0019187 beta-1,4-mannosyltransferase activity(GO:0019187)
0.0 1.1 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.3 0.9 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.3 0.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3 0.8 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 0.8 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)