Motif ID: Cbfb

Z-value: 0.372


Transcription factors associated with Cbfb:

Gene SymbolEntrez IDGene Name
Cbfb ENSMUSG00000031885.7 Cbfb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cbfbmm10_v2_chr8_+_105170668_1051706860.181.4e-01Click!


Activity profile for motif Cbfb.

activity profile for motif Cbfb


Sorted Z-values histogram for motif Cbfb

Sorted Z-values for motif Cbfb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cbfb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_27260327 2.445 ENSMUST00000033880.5
 Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr15_-_66801577 2.279 ENSMUST00000168589.1
 Sla
src-like adaptor
chr19_-_50678642 1.409 ENSMUST00000072685.6
ENSMUST00000164039.2
 Sorcs1

VPS10 domain receptor protein SORCS 1

chr19_-_50678485 1.303 ENSMUST00000111756.3
 Sorcs1
VPS10 domain receptor protein SORCS 1
chr14_+_101729907 1.249 ENSMUST00000100337.3
 Lmo7
LIM domain only 7
chr4_-_6990774 1.128 ENSMUST00000039987.3
 Tox
thymocyte selection-associated high mobility group box
chr14_-_101729690 0.841 ENSMUST00000066461.3
 Gm9922
predicted gene 9922
chr2_+_72297895 0.770 ENSMUST00000144111.1
 Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr7_-_90129339 0.685 ENSMUST00000181189.1
 2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr9_-_48480540 0.541 ENSMUST00000034524.3
 Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr5_+_104435112 0.497 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
 Spp1





secreted phosphoprotein 1





chr5_+_24364804 0.433 ENSMUST00000030834.4
ENSMUST00000115090.1
 Nos3

nitric oxide synthase 3, endothelial cell

chr15_+_99393219 0.418 ENSMUST00000159209.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6
chr11_-_83649349 0.408 ENSMUST00000001008.5
 Ccl3
chemokine (C-C motif) ligand 3
chr3_+_121291725 0.364 ENSMUST00000039442.7
 Alg14
asparagine-linked glycosylation 14
chr2_+_164948219 0.345 ENSMUST00000017881.2
 Mmp9
matrix metallopeptidase 9
chr15_+_99392948 0.278 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
 Tmbim6


transmembrane BAX inhibitor motif containing 6


chr12_+_95692212 0.274 ENSMUST00000057324.3
 Flrt2
fibronectin leucine rich transmembrane protein 2
chr15_+_99393574 0.218 ENSMUST00000162624.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6
chr15_+_99393610 0.214 ENSMUST00000159531.1
 Tmbim6
transmembrane BAX inhibitor motif containing 6
chr4_+_108847827 0.202 ENSMUST00000102738.2
 Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr1_-_16656843 0.188 ENSMUST00000115352.3
 Tceb1
transcription elongation factor B (SIII), polypeptide 1
chr17_-_64331817 0.134 ENSMUST00000172733.1
ENSMUST00000172818.1
 Pja2

praja 2, RING-H2 motif containing

chr1_-_63176653 0.127 ENSMUST00000027111.8
ENSMUST00000168099.2
 Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr1_+_63176818 0.093 ENSMUST00000129339.1
 Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr4_+_10874498 0.082 ENSMUST00000080517.7
ENSMUST00000101504.2
 2610301B20Rik

RIKEN cDNA 2610301B20 gene

chr14_+_64950037 0.054 ENSMUST00000043914.5
 Ints9
integrator complex subunit 9
chr4_-_117891994 0.042 ENSMUST00000030265.3
 Dph2
DPH2 homolog (S. cerevisiae)
chr1_-_174921813 0.041 ENSMUST00000055294.3
 Grem2
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.2 1.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.4 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915) positive regulation of receptor binding(GO:1900122)
0.0 0.5 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 2.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.0 1.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)