Motif ID: Cdc5l

Z-value: 0.735


Transcription factors associated with Cdc5l:

Gene SymbolEntrez IDGene Name
Cdc5l ENSMUSG00000023932.8 Cdc5l

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cdc5lmm10_v2_chr17_-_45433682_45433709-0.019.1e-01Click!


Activity profile for motif Cdc5l.

activity profile for motif Cdc5l


Sorted Z-values histogram for motif Cdc5l

Sorted Z-values for motif Cdc5l



Network of associatons between targets according to the STRING database.



First level regulatory network of Cdc5l

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_31447383 14.860 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr18_-_22850738 9.752 ENSMUST00000092015.4
ENSMUST00000069215.6
 Nol4

nucleolar protein 4

chr12_+_29528382 9.159 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr2_+_65620829 8.844 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr9_-_112187766 8.111 ENSMUST00000111872.2
ENSMUST00000164754.2
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_107497762 6.321 ENSMUST00000152474.1
ENSMUST00000060553.7
 A830010M20Rik

RIKEN cDNA A830010M20 gene

chr9_-_112187898 6.090 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_+_107497718 5.945 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene
chr9_-_55919605 5.485 ENSMUST00000037408.8
 Scaper
S phase cyclin A-associated protein in the ER
chr5_+_66968416 5.438 ENSMUST00000038188.7
 Limch1
LIM and calponin homology domains 1
chr5_+_66968559 4.734 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr9_-_96752822 4.451 ENSMUST00000152594.1
 Zbtb38
zinc finger and BTB domain containing 38
chr1_+_143640664 4.356 ENSMUST00000038252.2
 B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_+_180111339 3.696 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr10_+_17723220 2.967 ENSMUST00000038107.7
 Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr19_+_26749726 2.700 ENSMUST00000175842.1
 Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_64975762 2.697 ENSMUST00000156765.1
 Grb14
growth factor receptor bound protein 14
chr6_+_86526271 2.405 ENSMUST00000180896.1
 1600020E01Rik
RIKEN cDNA 1600020E01 gene
chr7_+_130577334 2.186 ENSMUST00000059145.7
ENSMUST00000084513.4
 Tacc2

transforming, acidic coiled-coil containing protein 2

chr4_-_149126688 2.113 ENSMUST00000030815.2
 Cort
cortistatin
chr12_+_74297474 1.884 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr4_+_95967205 1.792 ENSMUST00000030306.7
 Hook1
hook homolog 1 (Drosophila)
chr1_-_30863256 1.673 ENSMUST00000088310.3
 Phf3
PHD finger protein 3
chrX_+_136822781 1.439 ENSMUST00000113085.1
 Plp1
proteolipid protein (myelin) 1
chrX_-_37104523 1.430 ENSMUST00000130324.1
 Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr10_-_127189981 1.096 ENSMUST00000019611.7
 Arhgef25
Rho guanine nucleotide exchange factor (GEF) 25
chr5_-_31220491 1.073 ENSMUST00000031032.7
 Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr11_-_50953745 1.026 ENSMUST00000162420.1
ENSMUST00000051159.2
 Prop1

paired like homeodomain factor 1

chr7_-_103741322 1.000 ENSMUST00000051346.2
 Olfr629
olfactory receptor 629
chrX_+_136822671 0.905 ENSMUST00000033800.6
 Plp1
proteolipid protein (myelin) 1
chr1_-_97761538 0.746 ENSMUST00000171129.1
 Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr17_-_78684262 0.613 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr19_-_5797410 0.581 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr2_+_106695594 0.510 ENSMUST00000016530.7
 Mpped2
metallophosphoesterase domain containing 2
chr1_+_17601893 0.334 ENSMUST00000088476.2
 Pi15
peptidase inhibitor 15
chr2_-_72986716 0.333 ENSMUST00000112062.1
 Gm11084
predicted gene 11084

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
1.9 14.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.7 3.0 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.3 1.0 GO:0060126 hypophysis morphogenesis(GO:0048850) somatotropin secreting cell differentiation(GO:0060126)
0.3 14.2 GO:0034605 cellular response to heat(GO:0034605)
0.3 4.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 2.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 3.7 GO:0007097 nuclear migration(GO:0007097)
0.2 2.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 2.1 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 2.2 GO:0030953 astral microtubule organization(GO:0030953)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 10.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 2.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 1.8 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 4.5 GO:0006275 regulation of DNA replication(GO:0006275)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 14.9 GO:0031045 dense core granule(GO:0031045)
0.6 8.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 1.8 GO:0070695 FHF complex(GO:0070695)
0.1 2.7 GO:0071564 npBAF complex(GO:0071564)
0.0 4.5 GO:0072562 blood microparticle(GO:0072562)
0.0 1.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.7 GO:0042641 actomyosin(GO:0042641)
0.0 9.6 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.6 9.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.6 2.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 4.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.5 14.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.4 3.0 GO:0050693 LBD domain binding(GO:0050693)
0.2 0.7 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 4.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 14.8 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 12.0 GO:0003779 actin binding(GO:0003779)
0.0 1.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 3.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.2 GO:0035257 nuclear hormone receptor binding(GO:0035257)