Motif ID: Cebpa_Cebpg

Z-value: 0.672

Transcription factors associated with Cebpa_Cebpg:

Gene SymbolEntrez IDGene Name
Cebpa ENSMUSG00000034957.9 Cebpa
Cebpg ENSMUSG00000056216.8 Cebpg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpgmm10_v2_chr7_-_35056467_35056556-0.551.1e-06Click!
Cebpamm10_v2_chr7_+_35119285_351193010.483.0e-05Click!


Activity profile for motif Cebpa_Cebpg.

activity profile for motif Cebpa_Cebpg


Sorted Z-values histogram for motif Cebpa_Cebpg

Sorted Z-values for motif Cebpa_Cebpg



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpa_Cebpg

PNG image of the network

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Top targets:


Showing 1 to 20 of 135 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_65970610 8.469 ENSMUST00000127387.1
 Clu
clusterin
chr14_+_65971049 8.456 ENSMUST00000128539.1
 Clu
clusterin
chr14_+_65971164 7.616 ENSMUST00000144619.1
 Clu
clusterin
chr3_+_66219909 6.586 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr4_+_136143497 6.355 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr9_+_37367354 6.014 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr3_+_19957037 5.806 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
 Cp


ceruloplasmin


chr14_+_65970804 5.484 ENSMUST00000138191.1
 Clu
clusterin
chr15_-_88978958 4.584 ENSMUST00000042594.6
ENSMUST00000109368.1
 Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr7_-_79149042 4.207 ENSMUST00000032825.8
ENSMUST00000107409.3
 Mfge8

milk fat globule-EGF factor 8 protein

chr9_+_94669876 3.093 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr7_+_27447978 3.009 ENSMUST00000037399.9
ENSMUST00000108358.1
 Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr12_+_74297474 2.883 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr5_+_63812447 2.769 ENSMUST00000081747.3
 0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr5_-_51567717 2.763 ENSMUST00000127135.1
ENSMUST00000151104.1
 Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

chr1_+_169655493 2.589 ENSMUST00000027997.3
 Rgs5
regulator of G-protein signaling 5
chr11_-_110095937 2.106 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr1_+_134182404 2.093 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
 Chi3l1



chitinase 3-like 1



chr9_+_78615501 2.088 ENSMUST00000093812.4
 Cd109
CD109 antigen
chr13_-_117025505 2.087 ENSMUST00000022239.6
 Parp8
poly (ADP-ribose) polymerase family, member 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.0 30.0 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
2.2 6.6 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 6.4 GO:0071398 cellular response to fatty acid(GO:0071398)
0.3 5.8 GO:0046688 response to copper ion(GO:0046688)
0.0 5.0 GO:0007050 cell cycle arrest(GO:0007050)
0.9 4.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
1.1 4.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.4 3.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.6 3.0 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.9 2.8 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.7 2.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 2.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.3 2.3 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.5 2.1 GO:0072675 osteoclast fusion(GO:0072675)
0.3 1.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 1.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.8 GO:0046039 GTP metabolic process(GO:0046039)
0.5 1.6 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.5 GO:0033622 integrin activation(GO:0033622)
0.2 1.4 GO:0032264 IMP salvage(GO:0032264)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.3 30.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.1 7.9 GO:0055037 recycling endosome(GO:0055037)
0.2 5.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 5.5 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 2.8 GO:0097440 apical dendrite(GO:0097440)
0.0 2.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.9 GO:0030673 axolemma(GO:0030673)
0.0 1.6 GO:0030054 cell junction(GO:0030054)
0.4 1.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.5 GO:0005884 actin filament(GO:0005884)
0.3 0.9 GO:1990075 stereocilia ankle link complex(GO:0002142) periciliary membrane compartment(GO:1990075)
0.2 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.7 GO:0043596 nuclear replication fork(GO:0043596)
0.2 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 30.0 GO:0051787 misfolded protein binding(GO:0051787)
1.3 6.6 GO:0001849 complement component C1q binding(GO:0001849)
0.2 6.4 GO:0005504 fatty acid binding(GO:0005504)
1.2 5.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 4.7 GO:0008565 protein transporter activity(GO:0008565)
0.5 4.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.4 3.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.8 3.0 GO:0004074 biliverdin reductase activity(GO:0004074)
0.3 2.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 2.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 2.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 2.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 1.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.9 GO:0008483 transaminase activity(GO:0008483)
0.1 1.8 GO:0005522 profilin binding(GO:0005522)
0.0 1.7 GO:0015399 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 1.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.4 1.5 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)