Motif ID: Cebpb

Z-value: 1.011


Transcription factors associated with Cebpb:

Gene SymbolEntrez IDGene Name
Cebpb ENSMUSG00000056501.3 Cebpb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpbmm10_v2_chr2_+_167688915_1676889730.563.5e-07Click!


Activity profile for motif Cebpb.

activity profile for motif Cebpb


Sorted Z-values histogram for motif Cebpb

Sorted Z-values for motif Cebpb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_75152274 12.879 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr8_+_75093591 9.469 ENSMUST00000005548.6
Hmox1
heme oxygenase (decycling) 1
chr11_-_75422586 9.193 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr15_-_37459327 8.726 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr14_+_65971049 8.298 ENSMUST00000128539.1
Clu
clusterin
chr11_-_75422524 8.200 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr14_+_65970610 8.166 ENSMUST00000127387.1
Clu
clusterin
chr14_+_65970804 7.716 ENSMUST00000138191.1
Clu
clusterin
chr18_-_38601268 7.680 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr19_-_15924928 7.463 ENSMUST00000025542.3
Psat1
phosphoserine aminotransferase 1
chr14_+_65971164 7.414 ENSMUST00000144619.1
Clu
clusterin
chr2_+_25180737 7.271 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr19_-_50678642 7.007 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr12_-_56535047 6.865 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr4_-_148087961 6.046 ENSMUST00000030865.8
Agtrap
angiotensin II, type I receptor-associated protein
chr15_-_37458523 5.975 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr3_+_66219909 5.840 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr17_+_86963077 5.688 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr7_+_27447978 5.501 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr18_+_4994600 5.317 ENSMUST00000140448.1
Svil
supervillin
chr17_+_86963279 4.903 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr14_+_50944499 4.782 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr5_+_63812447 4.744 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr2_+_118111876 4.651 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr8_-_33929798 4.643 ENSMUST00000033995.7
ENSMUST00000033994.8
ENSMUST00000053251.5
Rbpms


RNA binding protein gene with multiple splicing


chr12_+_24572276 4.333 ENSMUST00000085553.5
Grhl1
grainyhead-like 1 (Drosophila)
chr3_+_19957037 4.291 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr7_+_126862431 4.284 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chr9_+_78615501 4.029 ENSMUST00000093812.4
Cd109
CD109 antigen
chrX_-_57338598 3.997 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr4_-_151044564 3.791 ENSMUST00000103204.4
Per3
period circadian clock 3
chr11_+_53519725 3.752 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
Sept8


septin 8


chr3_-_57575760 3.690 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr8_-_45410539 3.666 ENSMUST00000034056.4
ENSMUST00000167106.1
Tlr3

toll-like receptor 3

chr1_-_71653162 3.640 ENSMUST00000055226.6
Fn1
fibronectin 1
chr19_+_12460749 3.410 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr14_-_122451109 3.275 ENSMUST00000081580.2
Gm5089
predicted gene 5089
chr1_+_134182404 3.233 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr10_+_97482350 3.215 ENSMUST00000163448.2
Dcn
decorin
chr12_+_74297474 3.160 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr6_+_141249161 3.107 ENSMUST00000043259.7
Pde3a
phosphodiesterase 3A, cGMP inhibited
chr6_-_23248264 3.042 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_+_136172367 3.036 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr8_-_92355764 3.023 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr9_-_71771535 3.017 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
Cgnl1


cingulin-like 1


chr3_+_109123104 2.972 ENSMUST00000029477.6
Slc25a24
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24
chr7_+_126861947 2.818 ENSMUST00000037248.3
Hirip3
HIRA interacting protein 3
chr9_-_71163224 2.767 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr1_+_169655493 2.755 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr5_-_99037035 2.690 ENSMUST00000031277.6
Prkg2
protein kinase, cGMP-dependent, type II
chr12_+_88953399 2.684 ENSMUST00000057634.7
Nrxn3
neurexin III
chr11_+_110997487 2.461 ENSMUST00000106635.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr5_-_148399901 2.447 ENSMUST00000048116.8
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr3_+_87906842 2.427 ENSMUST00000159492.1
Hdgf
hepatoma-derived growth factor
chr14_+_47001336 2.393 ENSMUST00000125113.1
Samd4
sterile alpha motif domain containing 4
chr1_-_191183244 2.333 ENSMUST00000027941.8
Atf3
activating transcription factor 3
chr6_+_117907795 2.327 ENSMUST00000167657.1
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr4_+_150237694 2.256 ENSMUST00000141931.1
Eno1
enolase 1, alpha non-neuron
chr15_+_87625214 2.241 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr3_+_96104498 2.168 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
Otud7b



OTU domain containing 7B



chr5_-_99037342 2.167 ENSMUST00000161490.1
Prkg2
protein kinase, cGMP-dependent, type II
chr4_-_133967235 2.131 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_-_20332654 2.128 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr18_-_52529692 2.083 ENSMUST00000025409.7
Lox
lysyl oxidase
chr12_-_51971289 2.070 ENSMUST00000040583.5
Heatr5a
HEAT repeat containing 5A
chr13_-_49309217 2.043 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr11_+_6415443 2.033 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr2_-_25470031 1.979 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr19_-_34877880 1.917 ENSMUST00000112460.1
Pank1
pantothenate kinase 1
chr11_+_62077018 1.873 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr2_-_25469742 1.816 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chrX_-_134600976 1.792 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr7_-_45830776 1.789 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr18_-_52529847 1.744 ENSMUST00000171470.1
Lox
lysyl oxidase
chr2_+_119047129 1.715 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr2_+_119047116 1.715 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr19_-_3929723 1.693 ENSMUST00000051803.6
Aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr4_+_133176336 1.649 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr8_+_46471041 1.648 ENSMUST00000034046.5
Acsl1
acyl-CoA synthetase long-chain family member 1
chr5_+_31054766 1.648 ENSMUST00000013773.5
ENSMUST00000114646.1
Cad

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chr8_+_94037198 1.617 ENSMUST00000109556.2
ENSMUST00000093301.2
ENSMUST00000060632.7
Ogfod1


2-oxoglutarate and iron-dependent oxygenase domain containing 1


chr12_-_65172560 1.580 ENSMUST00000052201.8
Mis18bp1
MIS18 binding protein 1
chr13_+_63014934 1.557 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr15_+_59648644 1.557 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr5_+_31054821 1.555 ENSMUST00000174367.1
ENSMUST00000170329.1
ENSMUST00000031049.6
Cad


carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase


chr17_+_57358682 1.551 ENSMUST00000086763.5
ENSMUST00000004850.7
Emr1

EGF-like module containing, mucin-like, hormone receptor-like sequence 1

chr13_-_117025505 1.521 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr14_+_99298652 1.475 ENSMUST00000005279.6
Klf5
Kruppel-like factor 5
chr1_+_36307745 1.470 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr4_+_55350043 1.460 ENSMUST00000030134.8
Rad23b
RAD23b homolog (S. cerevisiae)
chr3_+_87906321 1.432 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr1_-_87573825 1.432 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr11_+_97685903 1.409 ENSMUST00000107583.2
Cisd3
CDGSH iron sulfur domain 3
chr2_+_116900152 1.407 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr11_-_83649349 1.398 ENSMUST00000001008.5
Ccl3
chemokine (C-C motif) ligand 3
chr7_-_127273919 1.397 ENSMUST00000082428.3
Sephs2
selenophosphate synthetase 2
chr15_+_59648350 1.380 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr4_-_43558386 1.363 ENSMUST00000130353.1
Tln1
talin 1
chr18_-_36726730 1.352 ENSMUST00000061829.6
Cd14
CD14 antigen
chr19_+_34290653 1.188 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr18_-_34931993 1.161 ENSMUST00000025218.7
Etf1
eukaryotic translation termination factor 1
chr4_+_115057410 1.131 ENSMUST00000136946.1
Tal1
T cell acute lymphocytic leukemia 1
chr7_+_90426312 1.116 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr17_+_48346401 1.103 ENSMUST00000024791.8
Trem2
triggering receptor expressed on myeloid cells 2
chr13_+_51100810 1.095 ENSMUST00000095797.5
Spin1
spindlin 1
chr19_+_6401675 1.069 ENSMUST00000113471.1
ENSMUST00000113469.2
Rasgrp2

RAS, guanyl releasing protein 2

chr3_+_146404844 1.049 ENSMUST00000106149.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr12_+_37241633 0.954 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr3_+_146404978 0.954 ENSMUST00000129978.1
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr17_+_32284772 0.948 ENSMUST00000181112.1
Gm26549
predicted gene, 26549
chr4_-_133967893 0.882 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr10_-_121626316 0.879 ENSMUST00000039810.7
Xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr2_+_155751117 0.871 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr4_+_152039315 0.870 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr13_+_31625802 0.830 ENSMUST00000042054.2
Foxf2
forkhead box F2
chr11_-_101551837 0.830 ENSMUST00000017290.4
Brca1
breast cancer 1
chr12_+_76837408 0.801 ENSMUST00000041008.9
Fntb
farnesyltransferase, CAAX box, beta
chr14_-_98169542 0.792 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr11_-_87826023 0.790 ENSMUST00000103177.3
Lpo
lactoperoxidase
chr3_+_123446913 0.732 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr14_-_18893376 0.717 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr18_-_64516547 0.644 ENSMUST00000025483.9
Nars
asparaginyl-tRNA synthetase
chr7_-_45434590 0.644 ENSMUST00000107771.3
ENSMUST00000141761.1
Ruvbl2

RuvB-like protein 2

chr9_-_103230262 0.634 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
Trf

Gm20425
transferrin

predicted gene 20425
chr14_-_68655804 0.629 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28

a disintegrin and metallopeptidase domain 28

chr1_+_178405881 0.619 ENSMUST00000027775.7
Efcab2
EF-hand calcium binding domain 2
chr13_+_63015167 0.607 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr14_-_54870913 0.605 ENSMUST00000146642.1
Homez
homeodomain leucine zipper-encoding gene
chrX_+_134601271 0.594 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chr10_-_62507737 0.593 ENSMUST00000020271.6
Srgn
serglycin
chr5_+_93093428 0.561 ENSMUST00000074733.7
Sept11
septin 11
chrX_+_134601179 0.542 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chr13_+_49682191 0.506 ENSMUST00000172254.1
Iars
isoleucine-tRNA synthetase
chr6_-_117907753 0.504 ENSMUST00000035534.4
4933440N22Rik
RIKEN cDNA 4933440N22 gene
chr15_-_101850778 0.503 ENSMUST00000023790.3
Krt1
keratin 1
chr11_-_46166397 0.449 ENSMUST00000020679.2
Nipal4
NIPA-like domain containing 4
chr4_-_108833544 0.436 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr16_-_21995478 0.412 ENSMUST00000074230.4
ENSMUST00000060673.6
Liph

lipase, member H

chr17_+_48346465 0.382 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr11_+_100320596 0.375 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr9_-_103230415 0.362 ENSMUST00000035158.9
Trf
transferrin
chr12_-_84194007 0.317 ENSMUST00000110294.1
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr11_-_33203588 0.306 ENSMUST00000037746.6
Tlx3
T cell leukemia, homeobox 3
chr11_+_49250512 0.304 ENSMUST00000101293.4
Mgat1
mannoside acetylglucosaminyltransferase 1
chr13_+_49682100 0.256 ENSMUST00000165316.1
ENSMUST00000047363.7
Iars

isoleucine-tRNA synthetase

chr11_-_78984831 0.248 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chr11_+_78037959 0.226 ENSMUST00000073660.6
Flot2
flotillin 2
chr11_+_99041237 0.221 ENSMUST00000017637.6
Igfbp4
insulin-like growth factor binding protein 4
chr15_-_96460838 0.218 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chr5_+_145140362 0.204 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chr5_+_115279666 0.173 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr10_+_80930071 0.169 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chr4_+_103119286 0.166 ENSMUST00000106857.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr11_+_49250583 0.165 ENSMUST00000129588.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chr4_-_133967953 0.113 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr1_+_82316452 0.101 ENSMUST00000027322.7
Rhbdd1
rhomboid domain containing 1
chr10_-_67096931 0.096 ENSMUST00000020023.7
Reep3
receptor accessory protein 3
chr7_+_45434876 0.074 ENSMUST00000107766.1
Gys1
glycogen synthase 1, muscle
chr14_+_49066495 0.047 ENSMUST00000037473.4
Ap5m1
adaptor-related protein complex 5, mu 1 subunit
chr6_+_54326955 0.044 ENSMUST00000059138.4
Prr15
proline rich 15
chr7_+_45434833 0.031 ENSMUST00000003964.8
Gys1
glycogen synthase 1, muscle
chr2_-_156180135 0.022 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
Rbm39




RNA binding motif protein 39




chr13_-_60936550 0.018 ENSMUST00000021880.9
Ctla2a
cytotoxic T lymphocyte-associated protein 2 alpha
chr10_+_80249441 0.007 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 31.6 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
4.3 12.9 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
3.2 9.5 GO:1904706 response to cisplatin(GO:0072718) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
2.3 6.9 GO:0021759 globus pallidus development(GO:0021759)
2.2 17.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
1.9 5.8 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
1.6 4.8 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
1.6 4.7 GO:0010752 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752) negative regulation of plasminogen activation(GO:0010757)
1.4 5.5 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.3 6.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.2 3.7 GO:0045349 regulation of dendritic cell cytokine production(GO:0002730) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-beta biosynthetic process(GO:0045359)
1.2 3.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161)
1.0 4.0 GO:0072675 osteoclast fusion(GO:0072675)
1.0 2.9 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.8 3.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.8 3.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.8 3.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.8 3.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.7 1.5 GO:0032499 detection of peptidoglycan(GO:0032499)
0.7 4.3 GO:0002934 desmosome organization(GO:0002934)
0.7 7.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.6 3.0 GO:0015867 ATP transport(GO:0015867)
0.6 2.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.6 10.6 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.5 3.7 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.5 3.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 1.5 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.5 4.9 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.4 2.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.4 3.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 2.4 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.4 1.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.4 2.8 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.4 6.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.4 1.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.4 3.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 1.4 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.3 1.4 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.3 3.8 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.3 2.1 GO:0015808 L-alanine transport(GO:0015808)
0.3 1.8 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.3 0.9 GO:0051031 tRNA transport(GO:0051031)
0.3 0.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 4.3 GO:0046688 response to copper ion(GO:0046688)
0.3 0.8 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 0.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 0.8 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.3 2.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 4.6 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.2 3.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 0.6 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.6 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 1.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 1.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.2 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 14.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.2 1.6 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 1.6 GO:0006449 regulation of translational termination(GO:0006449)
0.2 1.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 1.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 1.0 GO:0097460 ferrous iron import into cell(GO:0097460)
0.1 1.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 3.1 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.2 GO:1900426 positive regulation of defense response to bacterium(GO:1900426)
0.1 2.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 7.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 0.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 2.0 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 2.2 GO:0043171 peptide catabolic process(GO:0043171)
0.1 2.5 GO:0010107 potassium ion import(GO:0010107)
0.1 1.7 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 1.6 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) megakaryocyte development(GO:0035855)
0.1 0.2 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 2.8 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 1.5 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 1.1 GO:0007143 female meiotic division(GO:0007143)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 2.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.8 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.9 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.7 GO:0031638 zymogen activation(GO:0031638)
0.0 2.4 GO:0045727 positive regulation of translation(GO:0045727)
0.0 2.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 2.3 GO:0071229 cellular response to acid chemical(GO:0071229)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 31.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
2.8 8.3 GO:0005577 fibrinogen complex(GO:0005577)
1.2 17.4 GO:0043203 axon hillock(GO:0043203)
0.4 1.1 GO:0033193 Lsd1/2 complex(GO:0033193)
0.4 1.5 GO:0071942 XPC complex(GO:0071942)
0.3 0.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 3.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 12.9 GO:0005902 microvillus(GO:0005902)
0.1 4.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 5.3 GO:0043034 costamere(GO:0043034)
0.1 1.6 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0097433 dense body(GO:0097433)
0.1 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 0.6 GO:0042629 mast cell granule(GO:0042629)
0.1 0.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 9.7 GO:0005901 caveola(GO:0005901)
0.1 2.0 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.8 GO:0005581 collagen trimer(GO:0005581)
0.1 9.3 GO:0005884 actin filament(GO:0005884)
0.0 4.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 2.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 14.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.8 GO:0030027 lamellipodium(GO:0030027)
0.0 3.4 GO:0000776 kinetochore(GO:0000776)
0.0 1.9 GO:0030118 clathrin coat(GO:0030118)
0.0 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 11.2 GO:0005925 focal adhesion(GO:0005925)
0.0 5.0 GO:0005938 cell cortex(GO:0005938)
0.0 0.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 4.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.3 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.1 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 12.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
2.4 9.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.6 4.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.6 4.7 GO:0070052 collagen V binding(GO:0070052)
1.4 5.5 GO:0004074 biliverdin reductase activity(GO:0004074)
1.4 31.6 GO:0051787 misfolded protein binding(GO:0051787)
1.3 3.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
1.2 4.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
1.2 5.8 GO:0001849 complement component C1q binding(GO:0001849)
0.9 3.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.9 4.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.8 10.6 GO:0005522 profilin binding(GO:0005522)
0.8 3.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.7 3.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.6 2.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.6 3.6 GO:0045340 mercury ion binding(GO:0045340)
0.6 6.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.5 1.6 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.5 2.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.5 14.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.5 21.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 2.8 GO:0015265 urea channel activity(GO:0015265)
0.4 2.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.4 0.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.4 1.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 2.4 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.3 2.0 GO:0016936 galactoside binding(GO:0016936)
0.3 1.7 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3 7.5 GO:0008483 transaminase activity(GO:0008483)
0.3 2.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.3 0.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 0.8 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.3 2.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 4.6 GO:0008143 poly(A) binding(GO:0008143)
0.2 0.6 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 2.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 1.0 GO:0008199 ferric iron binding(GO:0008199)
0.2 1.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 1.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 6.0 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 2.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 3.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 2.4 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 1.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 2.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 3.1 GO:0030552 cAMP binding(GO:0030552)
0.1 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.8 GO:0005518 collagen binding(GO:0005518)
0.1 0.9 GO:0042556 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 4.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 3.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 5.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 5.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.9 GO:0015932 nucleobase-containing compound transmembrane transporter activity(GO:0015932)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)