Motif ID: Cebpb

Z-value: 1.011


Transcription factors associated with Cebpb:

Gene SymbolEntrez IDGene Name
Cebpb ENSMUSG00000056501.3 Cebpb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpbmm10_v2_chr2_+_167688915_1676889730.563.5e-07Click!


Activity profile for motif Cebpb.

activity profile for motif Cebpb


Sorted Z-values histogram for motif Cebpb

Sorted Z-values for motif Cebpb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpb

PNG image of the network

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Top targets:


Showing 1 to 20 of 164 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_75152274 12.879 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr8_+_75093591 9.469 ENSMUST00000005548.6
Hmox1
heme oxygenase (decycling) 1
chr11_-_75422586 9.193 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr15_-_37459327 8.726 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr14_+_65971049 8.298 ENSMUST00000128539.1
Clu
clusterin
chr11_-_75422524 8.200 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr14_+_65970610 8.166 ENSMUST00000127387.1
Clu
clusterin
chr14_+_65970804 7.716 ENSMUST00000138191.1
Clu
clusterin
chr18_-_38601268 7.680 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr19_-_15924928 7.463 ENSMUST00000025542.3
Psat1
phosphoserine aminotransferase 1
chr14_+_65971164 7.414 ENSMUST00000144619.1
Clu
clusterin
chr2_+_25180737 7.271 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr19_-_50678642 7.007 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr12_-_56535047 6.865 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr4_-_148087961 6.046 ENSMUST00000030865.8
Agtrap
angiotensin II, type I receptor-associated protein
chr15_-_37458523 5.975 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr3_+_66219909 5.840 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr17_+_86963077 5.688 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr7_+_27447978 5.501 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr18_+_4994600 5.317 ENSMUST00000140448.1
Svil
supervillin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 98 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.3 31.6 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
2.2 17.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 14.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
4.3 12.9 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.6 10.6 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
3.2 9.5 GO:1904706 response to cisplatin(GO:0072718) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 7.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.7 7.3 GO:0014807 regulation of somitogenesis(GO:0014807)
2.3 6.9 GO:0021759 globus pallidus development(GO:0021759)
1.3 6.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 6.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
1.9 5.8 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
1.4 5.5 GO:0042167 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.5 4.9 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
1.6 4.8 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
1.6 4.7 GO:0010752 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752) negative regulation of plasminogen activation(GO:0010757)
0.2 4.6 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.7 4.3 GO:0002934 desmosome organization(GO:0002934)
0.3 4.3 GO:0046688 response to copper ion(GO:0046688)
1.0 4.0 GO:0072675 osteoclast fusion(GO:0072675)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.5 31.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
1.2 17.4 GO:0043203 axon hillock(GO:0043203)
0.0 14.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 12.9 GO:0005902 microvillus(GO:0005902)
0.0 11.2 GO:0005925 focal adhesion(GO:0005925)
0.1 9.7 GO:0005901 caveola(GO:0005901)
0.1 9.3 GO:0005884 actin filament(GO:0005884)
2.8 8.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 5.3 GO:0043034 costamere(GO:0043034)
0.0 5.0 GO:0005938 cell cortex(GO:0005938)
0.0 4.9 GO:0031965 nuclear membrane(GO:0031965)
0.1 4.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 4.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.8 GO:0005581 collagen trimer(GO:0005581)
0.0 3.8 GO:0030027 lamellipodium(GO:0030027)
0.0 3.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.4 GO:0000776 kinetochore(GO:0000776)
0.2 3.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 2.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 31.6 GO:0051787 misfolded protein binding(GO:0051787)
0.5 21.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 14.7 GO:0043014 alpha-tubulin binding(GO:0043014)
2.6 12.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.8 10.6 GO:0005522 profilin binding(GO:0005522)
2.4 9.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 7.5 GO:0008483 transaminase activity(GO:0008483)
0.6 6.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 6.0 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
1.2 5.8 GO:0001849 complement component C1q binding(GO:0001849)
1.4 5.5 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 5.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 5.3 GO:0051015 actin filament binding(GO:0051015)
1.2 4.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
1.6 4.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.6 4.7 GO:0070052 collagen V binding(GO:0070052)
0.2 4.6 GO:0008143 poly(A) binding(GO:0008143)
0.9 4.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 4.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 3.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)