Motif ID: Creb1

Z-value: 1.500


Transcription factors associated with Creb1:

Gene SymbolEntrez IDGene Name
Creb1 ENSMUSG00000025958.8 Creb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1mm10_v2_chr1_+_64532790_64532815-0.244.1e-02Click!


Activity profile for motif Creb1.

activity profile for motif Creb1


Sorted Z-values histogram for motif Creb1

Sorted Z-values for motif Creb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_6084983 13.514 ENSMUST00000025704.2
 Cdca5
cell division cycle associated 5
chr12_-_56535047 12.850 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr7_-_38107490 10.951 ENSMUST00000108023.3
 Ccne1
cyclin E1
chr15_-_76710486 10.753 ENSMUST00000036852.7
 Recql4
RecQ protein-like 4
chr11_+_43528759 8.830 ENSMUST00000050574.6
 Ccnjl
cyclin J-like
chr13_-_29984219 8.270 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr2_+_156840966 7.883 ENSMUST00000109564.1
 Tgif2
TGFB-induced factor homeobox 2
chr6_+_113531675 7.263 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr10_+_121033960 6.916 ENSMUST00000020439.4
ENSMUST00000175867.1
 Wif1

Wnt inhibitory factor 1

chr9_+_122951051 6.627 ENSMUST00000040717.5
 Kif15
kinesin family member 15
chr7_-_30664986 6.356 ENSMUST00000019697.8
 Haus5
HAUS augmin-like complex, subunit 5
chr8_+_57511833 6.248 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr4_-_58553553 6.081 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
 Lpar1


lysophosphatidic acid receptor 1


chr2_-_127788854 6.053 ENSMUST00000028857.7
ENSMUST00000110357.1
 Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr7_-_137314394 5.784 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr7_-_118533298 5.639 ENSMUST00000098090.3
ENSMUST00000032887.3
 Coq7

demethyl-Q 7

chr11_-_106160101 5.565 ENSMUST00000045923.3
 Limd2
LIM domain containing 2
chr12_+_52097737 5.523 ENSMUST00000040090.9
 Nubpl
nucleotide binding protein-like
chr10_-_30200492 5.455 ENSMUST00000099985.4
 Cenpw
centromere protein W
chr3_+_135212557 5.445 ENSMUST00000062893.7
 Cenpe
centromere protein E

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 169 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.6 14.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.4 14.4 GO:0006270 DNA replication initiation(GO:0006270)
4.5 13.5 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 13.5 GO:0006364 rRNA processing(GO:0006364)
0.5 13.0 GO:0030488 tRNA methylation(GO:0030488)
4.3 12.8 GO:0021759 globus pallidus development(GO:0021759)
1.1 12.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
1.8 10.8 GO:0045875 DNA strand renaturation(GO:0000733) negative regulation of sister chromatid cohesion(GO:0045875)
0.5 9.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.7 9.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
1.3 8.9 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 8.5 GO:0051297 centrosome organization(GO:0051297)
0.1 8.4 GO:0098792 xenophagy(GO:0098792)
1.7 8.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.7 8.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.5 7.5 GO:0034501 protein localization to kinetochore(GO:0034501)
1.1 7.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 7.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 6.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 6.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 21.6 GO:0005667 transcription factor complex(GO:0005667)
0.3 18.4 GO:0005871 kinesin complex(GO:0005871)
0.1 17.0 GO:0000776 kinetochore(GO:0000776)
0.1 13.9 GO:0043198 dendritic shaft(GO:0043198)
1.5 13.5 GO:0008278 cohesin complex(GO:0008278)
0.2 13.4 GO:0000793 condensed chromosome(GO:0000793)
0.0 13.2 GO:0005730 nucleolus(GO:0005730)
0.2 10.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.6 9.4 GO:0042405 nuclear inclusion body(GO:0042405)
3.0 9.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 8.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.3 8.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.6 8.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.5 8.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.3 7.9 GO:0097546 ciliary base(GO:0097546)
0.1 7.9 GO:0005811 lipid particle(GO:0005811)
0.1 7.8 GO:0005643 nuclear pore(GO:0005643)
0.1 7.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
1.3 7.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.1 6.9 GO:0005663 DNA replication factor C complex(GO:0005663)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 128 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 30.2 GO:0044822 poly(A) RNA binding(GO:0044822)
0.3 22.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.3 18.4 GO:0003777 microtubule motor activity(GO:0003777)
2.4 14.5 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 13.8 GO:0003682 chromatin binding(GO:0003682)
0.1 13.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 13.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.1 13.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
2.2 10.8 GO:0000405 bubble DNA binding(GO:0000405)
0.0 9.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 9.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.3 9.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.6 8.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 7.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 7.0 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.6 6.9 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 6.9 GO:0017147 Wnt-protein binding(GO:0017147)
2.1 6.4 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
1.0 6.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.5 6.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)