Motif ID: Creb3l2

Z-value: 0.797


Transcription factors associated with Creb3l2:

Gene SymbolEntrez IDGene Name
Creb3l2 ENSMUSG00000038648.5 Creb3l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3l2mm10_v2_chr6_-_37442095_374421540.413.7e-04Click!


Activity profile for motif Creb3l2.

activity profile for motif Creb3l2


Sorted Z-values histogram for motif Creb3l2

Sorted Z-values for motif Creb3l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb3l2

PNG image of the network

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Top targets:


Showing 1 to 20 of 138 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_43239816 10.096 ENSMUST00000034512.5
 Oaf
OAF homolog (Drosophila)
chr7_+_19094594 7.983 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr2_-_105399286 7.893 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr11_+_100415722 7.348 ENSMUST00000107400.2
 Fkbp10
FK506 binding protein 10
chr11_+_100415697 7.223 ENSMUST00000001595.3
 Fkbp10
FK506 binding protein 10
chr7_-_25250720 7.126 ENSMUST00000116343.2
ENSMUST00000045847.8
 Erf

Ets2 repressor factor

chr10_+_20148920 6.636 ENSMUST00000116259.3
 Map7
microtubule-associated protein 7
chr11_-_94653964 6.496 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr15_+_34238026 6.457 ENSMUST00000022867.3
 Laptm4b
lysosomal-associated protein transmembrane 4B
chr6_+_56832059 6.386 ENSMUST00000031795.7
 Fkbp9
FK506 binding protein 9
chr3_-_20155069 6.312 ENSMUST00000184552.1
ENSMUST00000178328.1
 Gyg

glycogenin

chr2_-_92370999 6.190 ENSMUST00000176810.1
ENSMUST00000090582.4
 Gyltl1b

glycosyltransferase-like 1B

chr2_+_84840612 6.053 ENSMUST00000111625.1
 Slc43a1
solute carrier family 43, member 1
chr15_+_79516396 5.434 ENSMUST00000010974.7
 Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr8_+_14911663 5.345 ENSMUST00000084207.5
ENSMUST00000161162.1
ENSMUST00000110800.2
 Arhgef10


Rho guanine nucleotide exchange factor (GEF) 10


chr12_+_17544873 5.166 ENSMUST00000171737.1
 Odc1
ornithine decarboxylase, structural 1
chr5_-_135251209 5.061 ENSMUST00000062572.2
 Fzd9
frizzled homolog 9 (Drosophila)
chr16_-_78376758 4.916 ENSMUST00000023570.7
 Btg3
B cell translocation gene 3
chr2_-_92371039 4.867 ENSMUST00000068586.6
 Gyltl1b
glycosyltransferase-like 1B
chr7_+_79392305 4.561 ENSMUST00000117227.1
ENSMUST00000118959.1
ENSMUST00000036865.6
 Fanci


Fanconi anemia, complementation group I



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 78 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 21.0 GO:0061077 chaperone-mediated protein folding(GO:0061077)
1.1 15.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.7 11.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.7 8.0 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 7.9 GO:0043010 camera-type eye development(GO:0043010)
1.0 7.2 GO:0006621 protein retention in ER lumen(GO:0006621)
1.4 7.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 7.1 GO:0015804 neutral amino acid transport(GO:0015804)
1.3 6.5 GO:0072429 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
1.4 5.6 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 5.3 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
1.7 5.2 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 5.1 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.3 4.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 4.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.4 4.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.8 4.0 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 3.9 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 3.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 3.6 GO:0007050 cell cycle arrest(GO:0007050)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 28.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 15.8 GO:0005794 Golgi apparatus(GO:0005794)
0.0 9.0 GO:0005874 microtubule(GO:0005874)
0.0 7.8 GO:0005813 centrosome(GO:0005813)
0.0 6.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
1.3 6.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 5.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 5.3 GO:0015934 large ribosomal subunit(GO:0015934)
0.2 5.1 GO:0031527 filopodium membrane(GO:0031527)
0.4 4.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
1.0 4.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.8 3.9 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 3.8 GO:0031594 neuromuscular junction(GO:0031594)
0.5 3.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 3.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.5 3.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 2.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 2.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.2 GO:0014704 intercalated disc(GO:0014704)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 21.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
3.0 15.1 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.0 12.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 8.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.8 7.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 7.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 7.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 6.5 GO:0004519 endonuclease activity(GO:0004519)
0.5 6.3 GO:0005536 glucose binding(GO:0005536)
1.4 5.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 5.3 GO:0019894 kinesin binding(GO:0019894)
0.1 5.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 5.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 4.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 4.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 4.5 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 4.3 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
1.2 3.6 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.4 3.5 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116) steroid hormone binding(GO:1990239)
0.0 3.5 GO:0003924 GTPase activity(GO:0003924)