Motif ID: Ctcfl_Ctcf

Z-value: 1.147

Transcription factors associated with Ctcfl_Ctcf:

Gene SymbolEntrez IDGene Name
Ctcf ENSMUSG00000005698.9 Ctcf
Ctcfl ENSMUSG00000070495.5 Ctcfl

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ctcfmm10_v2_chr8_+_105636509_105636589-0.104.2e-01Click!
Ctcflmm10_v2_chr2_-_173119402_1731195250.037.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Ctcfl_Ctcf

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_137741601 15.677 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr5_-_137741102 15.372 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr2_+_65620829 13.492 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr18_+_36952621 13.187 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr9_+_34486125 12.667 ENSMUST00000115148.2
ENSMUST00000183580.1
Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr5_-_123132651 12.254 ENSMUST00000031401.5
Rhof
ras homolog gene family, member f
chr3_-_89160155 12.146 ENSMUST00000029686.3
Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr2_-_32353283 12.001 ENSMUST00000091089.5
ENSMUST00000113350.1
Dnm1

dynamin 1

chr19_+_6418731 11.963 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
Nrxn2


neurexin II


chr2_+_157914618 11.746 ENSMUST00000109523.1
Vstm2l
V-set and transmembrane domain containing 2-like
chr18_-_43393346 11.599 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr2_-_32353247 11.502 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
Dnm1


dynamin 1


chr13_-_54055650 11.289 ENSMUST00000021932.5
Drd1a
dopamine receptor D1A
chr8_-_84937347 11.019 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr5_+_135806859 10.834 ENSMUST00000126232.1
Srrm3
serine/arginine repetitive matrix 3
chr17_-_25433775 10.611 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
Cacna1h


calcium channel, voltage-dependent, T type, alpha 1H subunit


chr7_+_16310412 10.523 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr6_-_136173492 10.331 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr11_+_116918844 10.299 ENSMUST00000103027.3
Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr8_-_110168204 10.015 ENSMUST00000003754.6
Calb2
calbindin 2

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 209 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 40.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
3.0 23.9 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
4.8 19.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.3 18.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
3.3 16.6 GO:0046684 response to pyrethroid(GO:0046684)
0.2 15.5 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.2 15.2 GO:0035725 sodium ion transmembrane transport(GO:0035725)
3.4 13.5 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 13.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
2.5 12.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.6 12.0 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.8 11.6 GO:0051764 actin crosslink formation(GO:0051764)
0.4 11.5 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
2.8 11.0 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
3.5 10.6 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.6 10.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049) detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 10.3 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
1.5 10.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
2.9 8.7 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.2 8.6 GO:0050919 negative chemotaxis(GO:0050919)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 108 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.5 40.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
3.5 35.1 GO:0045298 tubulin complex(GO:0045298)
0.2 34.2 GO:0070382 exocytic vesicle(GO:0070382)
0.3 32.5 GO:0043198 dendritic shaft(GO:0043198)
1.9 28.4 GO:0043196 varicosity(GO:0043196)
0.1 23.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 17.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 12.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
2.4 12.1 GO:0044316 cone cell pedicle(GO:0044316)
0.1 12.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 11.5 GO:0042734 presynaptic membrane(GO:0042734)
0.3 10.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.9 10.3 GO:0043083 synaptic cleft(GO:0043083)
0.2 10.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.3 8.3 GO:0060077 inhibitory synapse(GO:0060077)
1.6 8.2 GO:0005683 U7 snRNP(GO:0005683)
0.5 8.1 GO:0031512 motile primary cilium(GO:0031512)
0.8 7.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 7.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 7.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 40.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.5 35.1 GO:0034185 apolipoprotein binding(GO:0034185)
3.4 33.8 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.6 25.0 GO:0001540 beta-amyloid binding(GO:0001540)
4.2 20.9 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 17.8 GO:0051117 ATPase binding(GO:0051117)
0.3 16.5 GO:0019894 kinesin binding(GO:0019894)
0.2 12.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
2.9 11.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 11.2 GO:0030165 PDZ domain binding(GO:0030165)
3.7 11.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
2.7 10.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 10.4 GO:0005246 calcium channel regulator activity(GO:0005246)
2.1 10.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.3 9.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
1.0 8.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
2.7 8.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.4 7.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
2.4 7.1 GO:0032450 oligo-1,6-glucosidase activity(GO:0004574) maltose alpha-glucosidase activity(GO:0032450)
0.4 7.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)