Motif ID: Ddit3

Z-value: 0.827


Transcription factors associated with Ddit3:

Gene SymbolEntrez IDGene Name
Ddit3 ENSMUSG00000025408.9 Ddit3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ddit3mm10_v2_chr10_+_127290774_1272908030.465.3e-05Click!


Activity profile for motif Ddit3.

activity profile for motif Ddit3


Sorted Z-values histogram for motif Ddit3

Sorted Z-values for motif Ddit3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ddit3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_109823585 12.882 ENSMUST00000161582.1
Nav3
neuron navigator 3
chr5_+_137553517 12.716 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b




actin-like 6B




chr19_-_59076069 10.464 ENSMUST00000047511.7
ENSMUST00000163821.1
4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr11_-_35798884 10.143 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr9_-_121495678 9.380 ENSMUST00000035120.4
Cck
cholecystokinin
chr15_-_66948419 9.092 ENSMUST00000167817.1
Ndrg1
N-myc downstream regulated gene 1
chr6_+_21215472 7.904 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr14_-_66868572 7.185 ENSMUST00000022629.8
Dpysl2
dihydropyrimidinase-like 2
chrX_+_103422010 7.160 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr10_+_112271123 6.065 ENSMUST00000092175.2
Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr15_-_43869993 5.929 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr15_-_59082026 5.737 ENSMUST00000080371.6
Mtss1
metastasis suppressor 1
chr18_+_37421418 5.562 ENSMUST00000053073.4
Pcdhb11
protocadherin beta 11
chr1_-_126492900 5.232 ENSMUST00000161954.1
Nckap5
NCK-associated protein 5
chr4_+_101550411 5.109 ENSMUST00000094953.4
ENSMUST00000106933.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chrX_+_166238901 5.042 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr6_+_86078070 5.012 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr3_+_9403049 5.001 ENSMUST00000180874.1
ENSMUST00000181331.1
ENSMUST00000181930.1
C030034L19Rik


RIKEN cDNA C030034L19 gene


chr13_+_42680565 4.864 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr8_-_99416397 4.807 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
Cdh8




cadherin 8




chr5_+_137288273 4.681 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr18_+_37307445 4.669 ENSMUST00000056712.2
Pcdhb4
protocadherin beta 4
chr7_+_126776939 4.612 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr8_+_12915879 4.571 ENSMUST00000110876.2
ENSMUST00000110879.2
Mcf2l

mcf.2 transforming sequence-like

chrX_-_162565514 4.535 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr9_-_44799179 4.499 ENSMUST00000114705.1
ENSMUST00000002100.7
Tmem25

transmembrane protein 25

chr1_-_126492683 4.481 ENSMUST00000162877.1
Nckap5
NCK-associated protein 5
chr18_+_37355271 4.293 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr7_-_126082406 4.291 ENSMUST00000073935.5
Gsg1l
GSG1-like
chr2_-_45117349 4.272 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr3_-_127409014 4.107 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
Ank2


ankyrin 2, brain


chr2_+_119351222 4.088 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chr3_-_127409044 3.967 ENSMUST00000182704.1
Ank2
ankyrin 2, brain
chr4_+_103619580 3.941 ENSMUST00000106827.1
Dab1
disabled 1
chr18_+_37333853 3.905 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr16_-_60605226 3.749 ENSMUST00000068860.6
Epha6
Eph receptor A6
chr3_-_127408986 3.582 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
Ank2


ankyrin 2, brain


chr6_+_115675983 3.524 ENSMUST00000068960.9
D830050J10Rik
RIKEN cDNA D830050J10 gene
chr3_-_127408937 3.517 ENSMUST00000183095.1
ENSMUST00000182610.1
Ank2

ankyrin 2, brain

chr2_+_181837854 3.489 ENSMUST00000029116.7
ENSMUST00000108754.1
Pcmtd2

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2

chr7_+_24112314 3.395 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr2_-_120850598 3.363 ENSMUST00000028740.4
Ttbk2
tau tubulin kinase 2
chr16_-_45724600 3.313 ENSMUST00000096057.4
Tagln3
transgelin 3
chr17_-_46890405 3.302 ENSMUST00000086675.3
A330017A19Rik
RIKEN cDNA A330017A19 gene
chr16_+_78301458 3.294 ENSMUST00000023572.7
Cxadr
coxsackie virus and adenovirus receptor
chr1_-_58586191 2.981 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr1_+_165461037 2.885 ENSMUST00000027853.5
Mpc2
mitochondrial pyruvate carrier 2
chr2_-_131328982 2.858 ENSMUST00000110194.1
Rnf24
ring finger protein 24
chr7_+_18884679 2.852 ENSMUST00000032573.6
Pglyrp1
peptidoglycan recognition protein 1
chr5_-_131538687 2.818 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr16_-_87432597 2.725 ENSMUST00000039449.7
Ltn1
listerin E3 ubiquitin protein ligase 1
chr2_-_130839683 2.681 ENSMUST00000119422.1
4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr15_-_83510793 2.626 ENSMUST00000154401.1
Ttll1
tubulin tyrosine ligase-like 1
chr15_-_83510861 2.584 ENSMUST00000109479.1
ENSMUST00000109480.1
ENSMUST00000016897.4
Ttll1


tubulin tyrosine ligase-like 1


chr5_-_36695969 2.543 ENSMUST00000031091.9
ENSMUST00000140063.1
D5Ertd579e

DNA segment, Chr 5, ERATO Doi 579, expressed

chr1_+_34121250 2.513 ENSMUST00000183006.1
Dst
dystonin
chr9_-_20644726 2.372 ENSMUST00000148631.1
ENSMUST00000131128.1
ENSMUST00000151861.1
ENSMUST00000131343.1
ENSMUST00000086458.3
Fbxl12




F-box and leucine-rich repeat protein 12




chrX_-_37104523 2.335 ENSMUST00000130324.1
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr5_-_74531619 2.320 ENSMUST00000113542.2
ENSMUST00000072857.6
ENSMUST00000121330.1
ENSMUST00000151474.1
Scfd2



Sec1 family domain containing 2



chr15_-_93595877 2.251 ENSMUST00000048982.4
Prickle1
prickle homolog 1 (Drosophila)
chr14_+_66868850 2.234 ENSMUST00000100453.1
Gm5464
predicted gene 5464
chr12_+_10390756 2.197 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr1_-_165460430 2.186 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chr6_+_125494419 2.140 ENSMUST00000181266.1
Gm26728
predicted gene, 26728
chr11_+_60728398 2.032 ENSMUST00000018743.4
Mief2
mitochondrial elongation factor 2
chr2_-_32961592 2.008 ENSMUST00000133832.1
ENSMUST00000124492.1
ENSMUST00000145578.1
ENSMUST00000127321.1
ENSMUST00000113200.1
Lrsam1




leucine rich repeat and sterile alpha motif containing 1




chr18_+_38993126 1.988 ENSMUST00000097593.2
Arhgap26
Rho GTPase activating protein 26
chr7_+_120677579 1.983 ENSMUST00000060175.6
BC030336
cDNA sequence BC030336
chr2_+_23069210 1.950 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr15_+_32244801 1.943 ENSMUST00000067458.6
Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr3_+_108186332 1.822 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
Amigo1



adhesion molecule with Ig like domain 1



chr11_-_79296906 1.822 ENSMUST00000068448.2
Gm9964
predicted gene 9964
chr7_-_31150981 1.766 ENSMUST00000085636.6
ENSMUST00000001280.7
Gramd1a

GRAM domain containing 1A

chr2_-_126876117 1.692 ENSMUST00000028843.5
Trpm7
transient receptor potential cation channel, subfamily M, member 7
chr2_-_148443543 1.658 ENSMUST00000099269.3
Cd93
CD93 antigen
chr16_+_36041184 1.585 ENSMUST00000042203.8
Wdr5b
WD repeat domain 5B
chr14_+_63606491 1.579 ENSMUST00000119973.2
Xkr6
X Kell blood group precursor related family member 6 homolog
chr16_-_15594507 1.578 ENSMUST00000115776.1
ENSMUST00000115777.3
Ube2v2

ubiquitin-conjugating enzyme E2 variant 2

chr1_+_87326997 1.526 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr1_+_87327008 1.514 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr9_-_45906369 1.457 ENSMUST00000161187.1
Rnf214
ring finger protein 214
chr8_+_25720054 1.391 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr11_+_70214105 1.382 ENSMUST00000094055.3
ENSMUST00000136328.1
ENSMUST00000126296.1
ENSMUST00000153993.2
Slc16a11



solute carrier family 16 (monocarboxylic acid transporters), member 11



chr11_-_116199040 1.364 ENSMUST00000066587.5
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr11_-_61930197 1.343 ENSMUST00000108710.1
Akap10
A kinase (PRKA) anchor protein 10
chr14_-_47568427 1.276 ENSMUST00000042988.6
Atg14
autophagy related 14
chr16_+_96145391 1.251 ENSMUST00000023913.8
ENSMUST00000135448.1
Wrb

tryptophan rich basic protein

chr11_+_116198853 1.243 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr8_-_47533439 1.242 ENSMUST00000039061.8
Trappc11
trafficking protein particle complex 11
chr16_+_24721842 1.239 ENSMUST00000115314.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr8_+_94386438 1.219 ENSMUST00000161576.1
Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr5_-_129887442 1.201 ENSMUST00000094280.3
Chchd2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr6_+_71322775 1.132 ENSMUST00000065248.7
Cd8b1
CD8 antigen, beta chain 1
chr11_+_54303798 1.102 ENSMUST00000093106.5
Acsl6
acyl-CoA synthetase long-chain family member 6
chr8_-_22476809 1.063 ENSMUST00000163774.1
ENSMUST00000033935.8
Smim19

small integral membrane protein 19

chr11_-_120643643 1.054 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
Pycr1




pyrroline-5-carboxylate reductase 1




chr1_+_174501796 1.041 ENSMUST00000030039.7
Fmn2
formin 2
chr7_-_75309262 1.034 ENSMUST00000165175.1
Sv2b
synaptic vesicle glycoprotein 2 b
chr6_+_88724667 0.960 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr8_-_35495487 0.951 ENSMUST00000033927.6
Eri1
exoribonuclease 1
chr2_-_164071089 0.903 ENSMUST00000018466.3
Tomm34
translocase of outer mitochondrial membrane 34
chr2_-_164071124 0.814 ENSMUST00000109384.3
Tomm34
translocase of outer mitochondrial membrane 34
chr18_+_40258361 0.777 ENSMUST00000091927.4
Kctd16
potassium channel tetramerisation domain containing 16
chr14_-_75787031 0.765 ENSMUST00000022580.6
Slc25a30
solute carrier family 25, member 30
chr8_+_94386486 0.722 ENSMUST00000034220.7
Herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr17_-_15564322 0.712 ENSMUST00000147532.1
Prdm9
PR domain containing 9
chr4_-_101844023 0.691 ENSMUST00000106919.1
B020004J07Rik
RIKEN cDNA B020004J07 gene
chr16_-_4939579 0.664 ENSMUST00000181498.1
Gm16861
predicted gene, 16861
chr5_+_31526989 0.647 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
Slc4a1ap


solute carrier family 4 (anion exchanger), member 1, adaptor protein


chr11_+_51763682 0.620 ENSMUST00000020653.5
Sar1b
SAR1 gene homolog B (S. cerevisiae)
chr10_+_79996479 0.615 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr1_-_39651165 0.604 ENSMUST00000053355.4
Creg2
cellular repressor of E1A-stimulated genes 2
chr8_-_67818284 0.590 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr3_-_53657339 0.588 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr5_+_32458974 0.564 ENSMUST00000015100.8
Ppp1cb
protein phosphatase 1, catalytic subunit, beta isoform
chr18_+_42275353 0.564 ENSMUST00000046972.7
ENSMUST00000091920.5
Rbm27

RNA binding motif protein 27

chr5_-_31526693 0.550 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
Supt7l


suppressor of Ty 7-like


chr14_+_65970804 0.534 ENSMUST00000138191.1
Clu
clusterin
chr6_+_89643982 0.520 ENSMUST00000000828.6
ENSMUST00000101171.1
Txnrd3

thioredoxin reductase 3

chr8_-_64693027 0.511 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr16_+_35983307 0.509 ENSMUST00000004054.6
Kpna1
karyopherin (importin) alpha 1
chr13_+_24614608 0.495 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr5_-_43981757 0.484 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr11_+_69846374 0.478 ENSMUST00000108632.1
Plscr3
phospholipid scramblase 3
chr11_-_59163696 0.424 ENSMUST00000137433.1
ENSMUST00000054523.5
Iba57

IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)

chr6_+_38534823 0.417 ENSMUST00000019833.4
1110001J03Rik
RIKEN cDNA 1110001J03 gene
chr11_-_96075655 0.407 ENSMUST00000090541.5
Atp5g1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr12_-_69681795 0.380 ENSMUST00000183277.1
ENSMUST00000035773.7
Sos2

son of sevenless homolog 2 (Drosophila)

chr13_-_104816908 0.361 ENSMUST00000022228.6
Cwc27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr10_+_84917616 0.316 ENSMUST00000038523.7
ENSMUST00000095385.3
Ric8b

resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)

chrX_+_94724569 0.313 ENSMUST00000101388.2
Zxdb
zinc finger, X-linked, duplicated B
chr1_-_195131536 0.285 ENSMUST00000075451.6
Cr1l
complement component (3b/4b) receptor 1-like
chr14_+_65971049 0.275 ENSMUST00000128539.1
Clu
clusterin
chr5_-_148399901 0.226 ENSMUST00000048116.8
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_+_166379097 0.217 ENSMUST00000027846.7
Tada1
transcriptional adaptor 1
chr7_-_42727017 0.211 ENSMUST00000166837.1
Gm17067
predicted gene 17067
chr14_-_79868398 0.207 ENSMUST00000179430.1
Gm10845
predicted gene 10845
chr10_+_127195240 0.195 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene
chr6_-_86793522 0.182 ENSMUST00000001187.8
Anxa4
annexin A4
chr1_+_173673651 0.166 ENSMUST00000085876.4
Pydc3
pyrin domain containing 3
chr13_-_113618549 0.117 ENSMUST00000109241.3
Snx18
sorting nexin 18
chr11_+_110997487 0.106 ENSMUST00000106635.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chrM_+_2743 0.096 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr9_-_108428484 0.079 ENSMUST00000076592.2
Ccdc36
coiled-coil domain containing 36
chr7_-_132852606 0.069 ENSMUST00000120425.1
Mettl10
methyltransferase like 10
chr9_-_70141484 0.028 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
1.9 5.7 GO:0034334 adherens junction maintenance(GO:0034334)
1.7 15.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.3 3.9 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
1.1 3.3 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
1.0 16.6 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.9 2.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.9 4.6 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.9 9.1 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.9 5.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.8 4.7 GO:0019695 choline metabolic process(GO:0019695)
0.8 6.1 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.8 2.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.7 2.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.7 5.0 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.7 4.3 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.6 5.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.5 1.6 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.5 2.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.5 2.9 GO:0098543 detection of bacterium(GO:0016045) negative regulation of natural killer cell activation(GO:0032815) detection of other organism(GO:0098543)
0.4 1.7 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.4 1.9 GO:0030242 pexophagy(GO:0030242)
0.4 7.8 GO:0045475 locomotor rhythm(GO:0045475)
0.3 1.0 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.3 1.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.3 1.9 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3 1.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 3.4 GO:1990403 embryonic brain development(GO:1990403)
0.2 0.7 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 4.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 5.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 2.0 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.2 2.2 GO:0042572 retinol metabolic process(GO:0042572)
0.2 1.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 0.5 GO:0030070 insulin processing(GO:0030070)
0.2 4.8 GO:0009409 response to cold(GO:0009409)
0.2 4.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 1.3 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.2 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 1.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 2.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.0 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 4.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.7 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.1 3.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 1.8 GO:0007413 axonal fasciculation(GO:0007413)
0.1 3.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 11.8 GO:0006338 chromatin remodeling(GO:0006338)
0.1 1.2 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 1.2 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 2.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 4.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.2 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.3 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.6 GO:0043583 ear development(GO:0043583) inner ear development(GO:0048839)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.7 GO:0098792 xenophagy(GO:0098792)
0.0 0.5 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 2.9 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.7 9.4 GO:0043203 axon hillock(GO:0043203)
0.6 1.9 GO:1990037 Lewy body core(GO:1990037)
0.6 12.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.6 15.2 GO:0031430 M band(GO:0031430)
0.6 2.5 GO:0031673 H zone(GO:0031673)
0.5 1.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.5 5.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.4 4.8 GO:0043083 synaptic cleft(GO:0043083)
0.4 1.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.4 1.2 GO:1990879 CST complex(GO:1990879)
0.4 15.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 9.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 4.3 GO:0032279 asymmetric synapse(GO:0032279)
0.2 4.7 GO:0005605 basal lamina(GO:0005605)
0.2 3.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.2 GO:0043196 varicosity(GO:0043196)
0.1 1.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 3.4 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 2.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 4.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 7.2 GO:0030426 growth cone(GO:0030426)
0.0 0.8 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 7.9 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 4.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.3 GO:0043209 myelin sheath(GO:0043209)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.4 GO:0045202 synapse(GO:0045202)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 7.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.2 4.7 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.7 2.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.7 2.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.7 3.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.7 3.3 GO:0086080 connexin binding(GO:0071253) protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.6 1.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.5 15.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 9.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 1.7 GO:0001849 complement component C1q binding(GO:0001849)
0.3 1.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.3 4.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.3 1.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 9.1 GO:0045296 cadherin binding(GO:0045296)
0.2 4.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.2 6.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.6 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.2 5.7 GO:0003785 actin monomer binding(GO:0003785)
0.2 3.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 5.0 GO:0030507 spectrin binding(GO:0030507)
0.1 4.1 GO:0005112 Notch binding(GO:0005112)
0.1 8.6 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 0.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 4.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 2.2 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.1 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 3.9 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 7.2 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 1.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 5.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) cobalt ion binding(GO:0050897)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 2.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.7 GO:0017022 myosin binding(GO:0017022)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.7 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)