Motif ID: Dlx1
Z-value: 0.954
Transcription factors associated with Dlx1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Dlx1 | ENSMUSG00000041911.3 | Dlx1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Dlx1 | mm10_v2_chr2_+_71529085_71529110 | 0.47 | 3.8e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.6 | 22.4 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
2.1 | 6.2 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
2.1 | 8.2 | GO:0032788 | saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789) |
2.0 | 6.1 | GO:1904395 | regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
1.9 | 7.5 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
1.6 | 4.8 | GO:2000040 | regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
1.6 | 4.7 | GO:0008228 | opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
1.5 | 4.6 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
1.3 | 3.9 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
1.2 | 8.4 | GO:0019532 | oxalate transport(GO:0019532) |
1.1 | 3.2 | GO:0002554 | serotonin secretion by platelet(GO:0002554) interleukin-3 production(GO:0032632) beta selection(GO:0043366) |
1.0 | 3.1 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.9 | 6.6 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.9 | 5.4 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
0.8 | 2.4 | GO:0071492 | cellular response to UV-A(GO:0071492) |
0.8 | 4.0 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.8 | 2.3 | GO:2000314 | negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
0.7 | 9.4 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.7 | 2.0 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.6 | 4.2 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.6 | 1.7 | GO:0046110 | xanthine metabolic process(GO:0046110) |
0.6 | 2.2 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.5 | 2.6 | GO:0042167 | heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
0.5 | 1.5 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
0.5 | 2.8 | GO:0036233 | glycine import(GO:0036233) |
0.4 | 1.3 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
0.4 | 2.5 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
0.4 | 1.6 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
0.4 | 2.8 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.4 | 1.2 | GO:0072592 | oxygen metabolic process(GO:0072592) |
0.4 | 1.2 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
0.4 | 2.7 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
0.4 | 1.5 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.3 | 2.3 | GO:0015791 | polyol transport(GO:0015791) urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918) |
0.3 | 2.2 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
0.3 | 1.6 | GO:0015819 | lysine transport(GO:0015819) |
0.3 | 2.5 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.3 | 8.2 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.3 | 2.4 | GO:2000809 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809) |
0.3 | 2.6 | GO:0046541 | saliva secretion(GO:0046541) |
0.3 | 3.4 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
0.3 | 2.3 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
0.3 | 0.8 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.3 | 1.3 | GO:0030091 | protein repair(GO:0030091) |
0.3 | 0.8 | GO:0010898 | positive regulation of triglyceride catabolic process(GO:0010898) |
0.2 | 1.0 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
0.2 | 1.6 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
0.2 | 0.7 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.2 | 0.6 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
0.2 | 4.3 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.2 | 1.4 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.2 | 1.4 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.2 | 1.7 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.2 | 5.0 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.2 | 0.9 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.2 | 0.5 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.2 | 0.7 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.2 | 2.3 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
0.2 | 1.6 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
0.2 | 2.4 | GO:0048240 | sperm capacitation(GO:0048240) |
0.2 | 1.1 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) |
0.2 | 0.5 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.2 | 1.7 | GO:0051923 | sulfation(GO:0051923) |
0.2 | 1.1 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.1 | 11.4 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
0.1 | 4.8 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
0.1 | 2.9 | GO:0003417 | growth plate cartilage development(GO:0003417) |
0.1 | 0.4 | GO:0009193 | pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048) |
0.1 | 1.0 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
0.1 | 0.3 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.1 | 1.7 | GO:0034308 | primary alcohol metabolic process(GO:0034308) |
0.1 | 1.4 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
0.1 | 2.3 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.1 | 1.0 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.1 | 1.4 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 2.3 | GO:0006907 | pinocytosis(GO:0006907) |
0.1 | 0.5 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
0.1 | 0.8 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.1 | 1.1 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
0.1 | 1.0 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
0.1 | 1.1 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.1 | 0.4 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139) |
0.1 | 2.8 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
0.1 | 0.9 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.1 | 0.5 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
0.1 | 1.5 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.1 | 0.4 | GO:0071033 | nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
0.1 | 7.4 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.1 | 0.5 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.1 | 2.8 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
0.1 | 1.2 | GO:0006677 | glycosylceramide metabolic process(GO:0006677) |
0.1 | 1.0 | GO:0031017 | exocrine pancreas development(GO:0031017) |
0.1 | 0.5 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
0.1 | 0.6 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.1 | 0.3 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
0.1 | 0.4 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
0.1 | 0.9 | GO:0034383 | low-density lipoprotein particle clearance(GO:0034383) |
0.1 | 0.4 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.1 | 0.9 | GO:0006953 | acute-phase response(GO:0006953) |
0.1 | 1.6 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.1 | 0.4 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.1 | 0.7 | GO:0097186 | amelogenesis(GO:0097186) |
0.1 | 1.5 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
0.1 | 0.6 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.1 | 1.9 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
0.0 | 0.2 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
0.0 | 0.7 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.0 | 0.4 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.0 | 1.4 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 3.8 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
0.0 | 1.7 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.2 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.0 | 1.4 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.5 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
0.0 | 0.2 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
0.0 | 0.7 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
0.0 | 0.3 | GO:0006361 | transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363) |
0.0 | 0.5 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
0.0 | 0.4 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.0 | 0.9 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
0.0 | 0.6 | GO:0072520 | seminiferous tubule development(GO:0072520) |
0.0 | 1.2 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
0.0 | 0.4 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.0 | 2.5 | GO:0019882 | antigen processing and presentation(GO:0019882) |
0.0 | 0.9 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.3 | GO:0045019 | negative regulation of nitric oxide biosynthetic process(GO:0045019) visceral serous pericardium development(GO:0061032) negative regulation of nitric oxide metabolic process(GO:1904406) |
0.0 | 1.6 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
0.0 | 0.0 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
0.0 | 1.2 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.0 | 0.8 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
0.0 | 0.2 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) |
0.0 | 0.3 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.0 | 2.9 | GO:0042493 | response to drug(GO:0042493) |
0.0 | 0.1 | GO:0040031 | snRNA modification(GO:0040031) |
0.0 | 1.1 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 1.0 | GO:0007019 | microtubule depolymerization(GO:0007019) |
0.0 | 0.2 | GO:0009060 | aerobic respiration(GO:0009060) |
0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.8 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.0 | 0.5 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
0.0 | 0.6 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
0.0 | 0.4 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.0 | 0.8 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.0 | 0.8 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 0.4 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.0 | 0.2 | GO:0010107 | potassium ion import(GO:0010107) |
0.0 | 0.7 | GO:0006400 | tRNA modification(GO:0006400) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 22.4 | GO:0043205 | fibril(GO:0043205) |
0.8 | 3.2 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.7 | 2.9 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.5 | 8.9 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.5 | 2.4 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.5 | 8.2 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.4 | 9.4 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.3 | 1.0 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.3 | 1.2 | GO:0071438 | NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438) |
0.3 | 2.8 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.3 | 1.3 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.2 | 1.6 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.2 | 1.3 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.2 | 1.3 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.2 | 0.9 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.2 | 1.0 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.2 | 0.5 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
0.2 | 1.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.2 | 2.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 1.5 | GO:0034709 | methylosome(GO:0034709) |
0.1 | 0.9 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.1 | 12.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.1 | 0.5 | GO:0032133 | chromosome passenger complex(GO:0032133) |
0.1 | 3.3 | GO:0043034 | costamere(GO:0043034) |
0.1 | 2.2 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.1 | 1.4 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.1 | 1.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.1 | 0.6 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.1 | 0.4 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.1 | 0.1 | GO:0071920 | cleavage body(GO:0071920) |
0.1 | 1.0 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 1.8 | GO:0032590 | dendrite membrane(GO:0032590) |
0.1 | 1.5 | GO:0000776 | kinetochore(GO:0000776) |
0.1 | 0.4 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.1 | 0.6 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 0.4 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.1 | 0.8 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 0.4 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 3.1 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 11.2 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 6.4 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 7.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.6 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.9 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.8 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 1.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.3 | GO:0042629 | mast cell granule(GO:0042629) |
0.0 | 0.5 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.0 | 0.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 2.3 | GO:0005856 | cytoskeleton(GO:0005856) |
0.0 | 5.8 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 0.4 | GO:0031932 | TORC2 complex(GO:0031932) |
0.0 | 2.3 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
0.0 | 0.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.3 | GO:0005688 | U6 snRNP(GO:0005688) |
0.0 | 3.7 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 0.5 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 0.4 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.0 | 1.6 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.0 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.0 | 0.5 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 0.7 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 3.9 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.7 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 7.3 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
0.0 | 2.5 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 1.3 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 1.0 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.4 | GO:0005865 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 0.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.8 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 3.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 1.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 1.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.8 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 2.1 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 0.9 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.6 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 8.4 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.6 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 1.3 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
0.0 | 5.4 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.0 | 0.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.9 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 1.0 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
0.0 | 3.3 | GO:0005576 | extracellular region(GO:0005576) |
0.0 | 17.9 | GO:0070062 | extracellular exosome(GO:0070062) |
0.0 | 0.5 | GO:0030133 | transport vesicle(GO:0030133) |
0.0 | 1.2 | GO:0005925 | focal adhesion(GO:0005925) |
0.0 | 0.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.7 | 23.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
2.0 | 6.1 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
1.8 | 5.4 | GO:0008502 | melatonin receptor activity(GO:0008502) |
1.6 | 4.8 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
1.3 | 4.0 | GO:0019770 | IgG receptor activity(GO:0019770) |
1.0 | 4.0 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.9 | 4.7 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.8 | 8.4 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.7 | 2.8 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.7 | 2.6 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
0.6 | 1.7 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.5 | 1.6 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.5 | 4.2 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
0.5 | 1.4 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.5 | 2.8 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
0.5 | 3.7 | GO:0042609 | CD4 receptor binding(GO:0042609) |
0.5 | 8.2 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.4 | 1.7 | GO:0030151 | molybdenum ion binding(GO:0030151) |
0.4 | 1.2 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.4 | 3.2 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.4 | 2.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.4 | 6.2 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.4 | 1.5 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
0.4 | 2.3 | GO:0015265 | urea channel activity(GO:0015265) |
0.4 | 2.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.4 | 2.5 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.3 | 1.4 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.3 | 11.2 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.3 | 2.2 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.3 | 7.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.3 | 4.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.3 | 1.4 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.3 | 2.0 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.3 | 2.2 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
0.3 | 3.1 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.3 | 5.6 | GO:0043747 | protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790) |
0.3 | 1.0 | GO:0035877 | death effector domain binding(GO:0035877) |
0.2 | 9.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.2 | 1.6 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
0.2 | 10.6 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.2 | 1.3 | GO:0034452 | dynactin binding(GO:0034452) |
0.2 | 1.2 | GO:0009374 | biotin binding(GO:0009374) |
0.2 | 0.9 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
0.2 | 0.5 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
0.2 | 3.4 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.2 | 1.2 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.2 | 0.7 | GO:0051378 | primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378) |
0.2 | 2.0 | GO:0015279 | store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.2 | 0.6 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.1 | 0.4 | GO:0008521 | acetyl-CoA transporter activity(GO:0008521) |
0.1 | 0.7 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.1 | 0.8 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.1 | 0.4 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.1 | 1.3 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.1 | 2.3 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.1 | 1.0 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.1 | 0.9 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
0.1 | 3.9 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.1 | 1.4 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.1 | 2.1 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.1 | 1.8 | GO:0016594 | glycine binding(GO:0016594) |
0.1 | 0.4 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.1 | 0.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.1 | 1.8 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
0.1 | 0.8 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.1 | 2.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.1 | 1.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.1 | 1.6 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
0.1 | 0.4 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.1 | 0.5 | GO:0035174 | histone serine kinase activity(GO:0035174) |
0.1 | 1.7 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.1 | 1.9 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.1 | 0.4 | GO:0000150 | recombinase activity(GO:0000150) crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.1 | 1.2 | GO:0017161 | JUN kinase phosphatase activity(GO:0008579) phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
0.1 | 2.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 1.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 0.6 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 0.4 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
0.1 | 0.9 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 1.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 1.4 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
0.0 | 0.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 1.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.4 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.0 | 0.4 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.0 | 0.6 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 0.3 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
0.0 | 5.9 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 2.9 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.0 | 1.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 0.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 1.1 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 3.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 1.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 1.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.4 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
0.0 | 2.8 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 7.8 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 8.8 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.4 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.0 | 1.6 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
0.0 | 0.2 | GO:0002135 | CTP binding(GO:0002135) sulfonylurea receptor binding(GO:0017098) |
0.0 | 3.6 | GO:0000982 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) |
0.0 | 1.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.5 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.5 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 4.5 | GO:0008168 | methyltransferase activity(GO:0008168) |
0.0 | 0.3 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 1.3 | GO:0016782 | transferase activity, transferring sulfur-containing groups(GO:0016782) |
0.0 | 0.2 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
0.0 | 2.8 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 2.0 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
0.0 | 0.6 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
0.0 | 0.3 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.8 | GO:0046921 | alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
0.0 | 0.8 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.1 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
0.0 | 0.2 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |