Motif ID: Dmc1

Z-value: 0.983


Transcription factors associated with Dmc1:

Gene SymbolEntrez IDGene Name
Dmc1 ENSMUSG00000022429.10 Dmc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dmc1mm10_v2_chr15_-_79605084_79605114-0.161.7e-01Click!


Activity profile for motif Dmc1.

activity profile for motif Dmc1


Sorted Z-values histogram for motif Dmc1

Sorted Z-values for motif Dmc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Dmc1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_66386292 5.602 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr1_-_38821215 5.501 ENSMUST00000039612.4
 Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr2_+_14229390 5.324 ENSMUST00000028045.2
 Mrc1
mannose receptor, C type 1
chr16_-_43979050 4.826 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr14_+_75955003 4.550 ENSMUST00000050120.2
 Kctd4
potassium channel tetramerisation domain containing 4
chr1_-_173942445 4.258 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr2_-_104257400 4.241 ENSMUST00000141159.1
 D430041D05Rik
RIKEN cDNA D430041D05 gene
chr18_-_82406777 3.905 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr18_+_61105561 3.737 ENSMUST00000025523.6
 Csf1r
colony stimulating factor 1 receptor
chr1_-_79440039 3.717 ENSMUST00000049972.4
 Scg2
secretogranin II
chr4_-_141598206 3.678 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
 Fblim1


filamin binding LIM protein 1


chr18_+_37484955 3.574 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr7_-_14562171 3.518 ENSMUST00000181796.1
 Vmn1r90
vomeronasal 1 receptor 90
chr10_+_69534208 3.457 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
 Ank3





ankyrin 3, epithelial





chr5_+_37185897 3.436 ENSMUST00000094840.3
 Gm1043
predicted gene 1043
chr4_+_118961578 3.401 ENSMUST00000058651.4
 Lao1
L-amino acid oxidase 1
chr2_+_130405256 3.392 ENSMUST00000110281.1
ENSMUST00000028898.3
 1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr15_-_43869993 3.285 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chrX_+_155262443 3.228 ENSMUST00000026324.9
 Acot9
acyl-CoA thioesterase 9
chr16_+_72663143 3.116 ENSMUST00000023600.7
 Robo1
roundabout homolog 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 189 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 6.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.5 5.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 5.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 5.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 5.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
1.3 5.0 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 4.8 GO:0018345 protein palmitoylation(GO:0018345)
0.9 4.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 4.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 4.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
1.3 3.9 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.1 3.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 3.3 GO:0030500 regulation of bone mineralization(GO:0030500)
1.0 3.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 3.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.6 3.0 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.3 3.0 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.6 2.9 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.4 2.9 GO:0097460 ferrous iron import into cell(GO:0097460)
0.3 2.9 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 6.7 GO:0010008 endosome membrane(GO:0010008)
0.2 6.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 5.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.7 5.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 4.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 4.0 GO:0008021 synaptic vesicle(GO:0008021)
0.2 3.7 GO:0031045 dense core granule(GO:0031045)
0.1 3.7 GO:0031672 A band(GO:0031672)
0.0 3.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 3.1 GO:0030673 axolemma(GO:0030673)
0.1 3.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 2.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 2.7 GO:0009986 cell surface(GO:0009986)
0.1 2.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 2.0 GO:0070688 MLL5-L complex(GO:0070688)
0.1 2.0 GO:0031941 filamentous actin(GO:0031941)
0.2 1.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.4 1.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.8 GO:0044294 dendritic growth cone(GO:0044294)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 146 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 7.5 GO:0031005 filamin binding(GO:0031005)
0.4 5.9 GO:0005537 mannose binding(GO:0005537)
0.2 5.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 5.6 GO:0042287 MHC protein binding(GO:0042287)
0.2 4.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 4.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 4.2 GO:0003779 actin binding(GO:0003779)
0.1 4.1 GO:0070888 E-box binding(GO:0070888)
0.1 4.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 4.1 GO:0019208 phosphatase regulator activity(GO:0019208)
1.3 3.9 GO:0004966 galanin receptor activity(GO:0004966)
0.2 3.7 GO:0042056 chemoattractant activity(GO:0042056)
1.1 3.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 3.4 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.3 GO:0005178 integrin binding(GO:0005178)
1.1 3.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 3.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.6 3.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)