Motif ID: E2f6

Z-value: 1.394


Transcription factors associated with E2f6:

Gene SymbolEntrez IDGene Name
E2f6 ENSMUSG00000057469.7 E2f6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f6mm10_v2_chr12_+_16810940_168109780.681.3e-10Click!


Activity profile for motif E2f6.

activity profile for motif E2f6


Sorted Z-values histogram for motif E2f6

Sorted Z-values for motif E2f6



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_60893430 31.674 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr15_-_98004695 24.445 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr15_-_98004634 23.797 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr2_+_71529085 20.915 ENSMUST00000152711.1
Dlx1
distal-less homeobox 1
chr17_-_35516780 13.420 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr13_+_48261427 12.975 ENSMUST00000021810.1
Id4
inhibitor of DNA binding 4
chr6_+_108660616 12.792 ENSMUST00000032194.4
Bhlhe40
basic helix-loop-helix family, member e40
chr7_-_38107490 11.938 ENSMUST00000108023.3
Ccne1
cyclin E1
chr19_-_45742873 11.479 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
Fgf8


fibroblast growth factor 8


chr7_+_102441685 11.100 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr9_+_65890237 10.826 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr4_-_137796350 10.567 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr1_+_74391479 10.535 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr13_-_29984219 10.407 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr2_-_172940299 10.253 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr2_-_71546745 10.145 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr1_-_172206775 9.997 ENSMUST00000013842.5
ENSMUST00000111247.1
Pea15a

phosphoprotein enriched in astrocytes 15A

chr6_+_108660772 9.993 ENSMUST00000163617.1
Bhlhe40
basic helix-loop-helix family, member e40
chr7_+_19094594 9.838 ENSMUST00000049454.5
Six5
sine oculis-related homeobox 5
chr12_-_56536895 9.794 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr11_+_70540260 9.757 ENSMUST00000018429.5
ENSMUST00000108557.3
ENSMUST00000108556.1
Pld2


phospholipase D2


chr2_+_71389239 9.527 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr8_-_105347885 9.360 ENSMUST00000014922.4
Fhod1
formin homology 2 domain containing 1
chr11_+_82388900 9.182 ENSMUST00000054245.4
ENSMUST00000092852.2
Tmem132e

transmembrane protein 132E

chr7_+_13278778 9.114 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr5_+_137350101 9.073 ENSMUST00000061244.8
Ephb4
Eph receptor B4
chr6_+_6863769 8.896 ENSMUST00000031768.6
Dlx6
distal-less homeobox 6
chr2_+_71528657 8.880 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr1_-_20820213 8.856 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr12_+_103314944 8.829 ENSMUST00000179363.1
Fam181a
family with sequence similarity 181, member A
chr17_-_32166879 8.699 ENSMUST00000087723.3
Notch3
notch 3
chrX_+_142681398 8.690 ENSMUST00000112889.1
ENSMUST00000101198.2
ENSMUST00000112891.1
ENSMUST00000087333.2
Tmem164



transmembrane protein 164



chr11_+_88718442 8.641 ENSMUST00000138007.1
C030037D09Rik
RIKEN cDNA C030037D09 gene
chrX_+_100729917 8.630 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr1_-_64737735 8.497 ENSMUST00000063982.5
ENSMUST00000116133.2
Fzd5

frizzled homolog 5 (Drosophila)

chr10_-_7212222 8.446 ENSMUST00000015346.5
Cnksr3
Cnksr family member 3
chr16_+_91225550 8.413 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr12_-_119238794 8.361 ENSMUST00000026360.8
Itgb8
integrin beta 8
chrX_-_141725181 8.328 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr1_-_172206684 8.176 ENSMUST00000155109.1
Pea15a
phosphoprotein enriched in astrocytes 15A
chr13_-_111808938 8.146 ENSMUST00000109267.2
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr2_-_147186389 8.103 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr13_-_71963713 8.087 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr2_-_91931774 8.030 ENSMUST00000069423.6
Mdk
midkine
chr19_+_38481057 8.027 ENSMUST00000182481.1
Plce1
phospholipase C, epsilon 1
chr11_-_102946688 7.782 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr10_+_94036001 7.780 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr10_+_108332173 7.682 ENSMUST00000095313.3
Pawr
PRKC, apoptosis, WT1, regulator
chr12_+_24708241 7.622 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr2_+_72476225 7.595 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr7_-_99353104 7.588 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr17_-_25570678 7.575 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr11_-_101785252 7.515 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr15_-_103366763 7.480 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr12_+_24708984 7.471 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr8_-_90348343 7.467 ENSMUST00000109621.3
Tox3
TOX high mobility group box family member 3
chr2_+_72476159 7.450 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr14_-_67715585 7.442 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr4_-_133753611 7.403 ENSMUST00000145664.2
ENSMUST00000105897.3
Arid1a

AT rich interactive domain 1A (SWI-like)

chr6_+_42350000 7.393 ENSMUST00000164375.1
Zyx
zyxin
chr11_+_102604370 7.329 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr9_-_21798502 7.311 ENSMUST00000034717.5
Kank2
KN motif and ankyrin repeat domains 2
chr2_-_91931696 7.311 ENSMUST00000090602.5
Mdk
midkine
chr17_+_56303321 7.280 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr3_-_98339921 7.265 ENSMUST00000065793.5
Phgdh
3-phosphoglycerate dehydrogenase
chr1_+_74771886 7.257 ENSMUST00000006716.6
Wnt6
wingless-related MMTV integration site 6
chrX_+_96096034 7.255 ENSMUST00000117399.1
Msn
moesin
chr4_-_11386757 7.175 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chrX_-_52613913 7.169 ENSMUST00000069360.7
Gpc3
glypican 3
chr12_+_3807017 7.101 ENSMUST00000020991.8
ENSMUST00000172509.1
Dnmt3a

DNA methyltransferase 3A

chr8_-_90348126 7.086 ENSMUST00000176034.1
ENSMUST00000176616.1
Tox3

TOX high mobility group box family member 3

chr12_-_46818749 7.071 ENSMUST00000021438.6
Nova1
neuro-oncological ventral antigen 1
chr13_-_63565520 7.044 ENSMUST00000021921.5
Ptch1
patched homolog 1
chr18_-_39490649 6.991 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr11_+_98907801 6.870 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chr3_+_137864487 6.858 ENSMUST00000041045.7
H2afz
H2A histone family, member Z
chr1_+_59482133 6.844 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr12_+_69168808 6.819 ENSMUST00000110621.1
Lrr1
leucine rich repeat protein 1
chr11_-_88718165 6.773 ENSMUST00000107908.1
Msi2
musashi RNA-binding protein 2
chrX_-_162159717 6.765 ENSMUST00000087085.3
Nhs
Nance-Horan syndrome (human)
chrX_-_143393893 6.750 ENSMUST00000166406.2
Chrdl1
chordin-like 1
chr13_-_100775844 6.698 ENSMUST00000075550.3
Cenph
centromere protein H
chr7_-_133123312 6.590 ENSMUST00000124096.1
ENSMUST00000171022.1
ENSMUST00000163601.1
ENSMUST00000165534.1
ENSMUST00000033269.8
Fgfr2
Ctbp2



fibroblast growth factor receptor 2
C-terminal binding protein 2



chrX_-_48034842 6.491 ENSMUST00000039026.7
Apln
apelin
chr5_+_33721724 6.487 ENSMUST00000067150.7
ENSMUST00000169212.2
ENSMUST00000114411.2
ENSMUST00000164207.3
Fgfr3



fibroblast growth factor receptor 3



chr2_-_91931675 6.486 ENSMUST00000111309.1
Mdk
midkine
chr8_+_12395287 6.463 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chrX_-_52613936 6.449 ENSMUST00000114857.1
Gpc3
glypican 3
chrX_+_141475385 6.448 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr4_+_126556935 6.388 ENSMUST00000048391.8
Clspn
claspin
chr19_-_40271506 6.366 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr14_+_51984857 6.334 ENSMUST00000100639.4
ENSMUST00000182909.1
ENSMUST00000182760.1
ENSMUST00000182061.1
ENSMUST00000182193.1
Arhgef40




Rho guanine nucleotide exchange factor (GEF) 40




chr1_-_163313661 6.327 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr11_-_94601862 6.270 ENSMUST00000103164.3
Acsf2
acyl-CoA synthetase family member 2
chr6_+_42349826 6.234 ENSMUST00000070635.6
Zyx
zyxin
chr6_-_125313844 6.207 ENSMUST00000032489.7
Ltbr
lymphotoxin B receptor
chr13_+_15463837 6.072 ENSMUST00000110510.3
Gli3
GLI-Kruppel family member GLI3
chr17_+_56040350 6.042 ENSMUST00000002914.8
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr17_-_70851189 6.030 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr4_+_126556994 5.945 ENSMUST00000147675.1
Clspn
claspin
chr19_-_58454435 5.935 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr7_+_144838590 5.921 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr17_-_56830916 5.906 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chrX_+_100730178 5.832 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr4_+_11191726 5.783 ENSMUST00000029866.9
ENSMUST00000108324.3
Ccne2

cyclin E2

chr3_-_8667033 5.775 ENSMUST00000042412.3
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr2_-_64097994 5.741 ENSMUST00000131615.2
Fign
fidgetin
chr1_-_128103016 5.669 ENSMUST00000097597.2
Zranb3
zinc finger, RAN-binding domain containing 3
chr2_-_165473187 5.654 ENSMUST00000029208.8
ENSMUST00000109279.2
Slc13a3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr17_+_56303396 5.607 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr9_+_118926453 5.580 ENSMUST00000073109.5
Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr6_-_72235559 5.559 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr2_+_31950257 5.558 ENSMUST00000001920.7
Aif1l
allograft inflammatory factor 1-like
chr2_+_125247190 5.531 ENSMUST00000082122.7
Dut
deoxyuridine triphosphatase
chr1_-_133424377 5.529 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr2_+_84839395 5.477 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr5_+_137350371 5.393 ENSMUST00000166239.1
ENSMUST00000111054.1
Ephb4

Eph receptor B4

chr3_+_90541146 5.385 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100a16


S100 calcium binding protein A16


chr2_+_164562579 5.347 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr6_-_53820764 5.250 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chrX_-_48454152 5.225 ENSMUST00000114958.1
Elf4
E74-like factor 4 (ets domain transcription factor)
chr17_-_24960620 5.181 ENSMUST00000024981.7
Hn1l
hematological and neurological expressed 1-like
chr3_-_154330543 5.091 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr2_-_36104060 5.074 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr3_-_87174518 5.027 ENSMUST00000041732.8
Kirrel
kin of IRRE like (Drosophila)
chr12_+_3807076 4.959 ENSMUST00000174817.1
Dnmt3a
DNA methyltransferase 3A
chr19_-_58454580 4.957 ENSMUST00000129100.1
ENSMUST00000123957.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr10_+_128232065 4.938 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless




timeless circadian clock 1




chr18_+_60911757 4.923 ENSMUST00000040359.5
Arsi
arylsulfatase i
chr19_-_58455161 4.923 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr15_-_94404258 4.879 ENSMUST00000035342.4
ENSMUST00000155907.1
Adamts20

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20

chr6_-_23248264 4.835 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr2_-_125723387 4.818 ENSMUST00000042246.7
Shc4
SHC (Src homology 2 domain containing) family, member 4
chr2_-_68472138 4.817 ENSMUST00000102715.3
Stk39
serine/threonine kinase 39
chr9_+_44134562 4.785 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr4_+_125490688 4.777 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr8_-_80057989 4.759 ENSMUST00000079038.2
Hhip
Hedgehog-interacting protein
chr11_-_76027726 4.754 ENSMUST00000021207.6
Fam101b
family with sequence similarity 101, member B
chr5_+_115845229 4.743 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr6_+_29735667 4.727 ENSMUST00000001812.4
Smo
smoothened homolog (Drosophila)
chr17_-_10840285 4.725 ENSMUST00000041463.6
Pacrg
PARK2 co-regulated
chr5_+_137787769 4.715 ENSMUST00000035852.7
Zcwpw1
zinc finger, CW type with PWWP domain 1
chr11_-_116335384 4.648 ENSMUST00000036215.7
Foxj1
forkhead box J1
chr2_-_137116624 4.630 ENSMUST00000028735.7
Jag1
jagged 1
chr12_+_3891728 4.613 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a

DNA methyltransferase 3A

chr1_-_9700209 4.596 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr4_-_133967296 4.577 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr16_-_10313940 4.569 ENSMUST00000078357.4
Emp2
epithelial membrane protein 2
chr11_+_119022962 4.553 ENSMUST00000026662.7
Cbx2
chromobox 2
chr11_-_69880971 4.502 ENSMUST00000050555.3
Kctd11
potassium channel tetramerisation domain containing 11
chr1_+_164249023 4.485 ENSMUST00000044021.5
Slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr2_-_156839790 4.484 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr5_-_36398090 4.483 ENSMUST00000037370.7
ENSMUST00000070720.6
Sorcs2

sortilin-related VPS10 domain containing receptor 2

chr11_+_88068242 4.451 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr13_+_112987802 4.449 ENSMUST00000038404.4
Ccno
cyclin O
chr8_+_94532990 4.428 ENSMUST00000048653.2
ENSMUST00000109537.1
Cpne2

copine II

chr4_+_141242850 4.399 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr11_-_88718078 4.399 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr3_+_137864573 4.398 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chrX_+_164269371 4.385 ENSMUST00000145412.1
ENSMUST00000033749.7
Pir

pirin

chr1_+_164249052 4.377 ENSMUST00000159230.1
Slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr5_+_110286306 4.371 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr5_-_28467093 4.363 ENSMUST00000002708.3
Shh
sonic hedgehog
chr16_-_18811615 4.324 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr5_-_138171248 4.324 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr3_+_121723515 4.323 ENSMUST00000029771.8
F3
coagulation factor III
chr4_+_8691303 4.321 ENSMUST00000051558.3
Chd7
chromodomain helicase DNA binding protein 7
chr14_-_98169542 4.310 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr4_+_8690399 4.305 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr9_+_92457369 4.271 ENSMUST00000034941.7
Plscr4
phospholipid scramblase 4
chr18_+_35118880 4.270 ENSMUST00000042345.6
Ctnna1
catenin (cadherin associated protein), alpha 1
chr14_+_51984826 4.261 ENSMUST00000093813.5
Arhgef40
Rho guanine nucleotide exchange factor (GEF) 40
chr5_+_117319258 4.260 ENSMUST00000111967.1
Vsig10
V-set and immunoglobulin domain containing 10
chr9_-_100546053 4.259 ENSMUST00000116522.1
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr7_-_127026479 4.239 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr10_+_20148920 4.235 ENSMUST00000116259.3
Map7
microtubule-associated protein 7
chr15_-_78529617 4.221 ENSMUST00000023075.8
C1qtnf6
C1q and tumor necrosis factor related protein 6
chr7_-_49636847 4.212 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr12_+_8771317 4.201 ENSMUST00000020911.7
Sdc1
syndecan 1
chr6_+_113531675 4.179 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr14_-_47276790 4.171 ENSMUST00000111792.1
ENSMUST00000111791.1
ENSMUST00000111790.1
Wdhd1


WD repeat and HMG-box DNA binding protein 1


chr2_-_160912292 4.127 ENSMUST00000109454.1
ENSMUST00000057169.4
Emilin3

elastin microfibril interfacer 3

chr18_-_13972617 4.111 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr14_+_122475397 4.089 ENSMUST00000075888.5
Zic2
zinc finger protein of the cerebellum 2
chr3_-_27710413 4.082 ENSMUST00000046157.4
Fndc3b
fibronectin type III domain containing 3B
chr11_-_115808068 4.074 ENSMUST00000132780.1
Caskin2
CASK-interacting protein 2
chr14_+_20929416 4.070 ENSMUST00000022369.7
Vcl
vinculin
chr2_+_27886416 4.017 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr2_-_157204483 4.015 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chrX_-_52165252 4.014 ENSMUST00000033450.2
Gpc4
glypican 4
chr8_-_111876661 3.998 ENSMUST00000034431.1
Tmem170
transmembrane protein 170
chr11_-_114795888 3.983 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chrX_+_71556874 3.964 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chrX_-_23365044 3.948 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr6_+_134929118 3.928 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr18_-_78206408 3.916 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr9_+_109095427 3.916 ENSMUST00000072093.6
Plxnb1
plexin B1
chr4_-_133968611 3.915 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr2_-_102186322 3.913 ENSMUST00000111222.1
ENSMUST00000058790.5
Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr11_-_74723829 3.883 ENSMUST00000102520.2
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
13.3 39.9 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
7.3 21.8 GO:0030421 defecation(GO:0030421)
6.8 13.6 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
5.5 16.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
5.2 62.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
4.4 17.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
4.4 4.4 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
3.8 11.5 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
3.8 7.6 GO:0072197 renal vesicle induction(GO:0072034) ureter morphogenesis(GO:0072197)
3.5 3.5 GO:0021593 rhombomere morphogenesis(GO:0021593)
3.4 13.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
3.3 9.8 GO:0021759 globus pallidus development(GO:0021759)
3.2 6.5 GO:0061144 alveolar secondary septum development(GO:0061144)
3.2 9.6 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
3.1 12.5 GO:0015888 thiamine transport(GO:0015888)
2.9 8.6 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221) ventricular compact myocardium morphogenesis(GO:0003223)
2.8 13.9 GO:0006348 chromatin silencing at telomere(GO:0006348)
2.7 13.7 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
2.7 8.1 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
2.7 8.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
2.6 5.3 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
2.6 7.8 GO:0061743 motor learning(GO:0061743)
2.6 10.3 GO:0003360 brainstem development(GO:0003360)
2.6 7.7 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
2.5 12.5 GO:0030916 otic vesicle formation(GO:0030916)
2.4 7.3 GO:0006566 threonine metabolic process(GO:0006566)
2.4 2.4 GO:0072554 blood vessel lumenization(GO:0072554)
2.3 18.8 GO:0044027 hypermethylation of CpG island(GO:0044027)
2.3 14.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
2.3 9.3 GO:0009957 epidermal cell fate specification(GO:0009957)
2.1 2.1 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
2.1 10.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
2.1 2.1 GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
2.0 6.1 GO:0060364 frontal suture morphogenesis(GO:0060364)
2.0 6.1 GO:0045659 eosinophil differentiation(GO:0030222) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.0 30.0 GO:0007530 sex determination(GO:0007530)
2.0 31.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
1.9 5.8 GO:0035907 dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
1.9 5.7 GO:0036292 DNA rewinding(GO:0036292)
1.8 7.3 GO:0003150 muscular septum morphogenesis(GO:0003150)
1.8 7.3 GO:0061113 pancreas morphogenesis(GO:0061113)
1.8 1.8 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
1.8 7.2 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
1.8 12.4 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
1.8 8.8 GO:0001705 ectoderm formation(GO:0001705)
1.7 5.2 GO:0001866 NK T cell proliferation(GO:0001866)
1.7 8.6 GO:2000680 regulation of rubidium ion transport(GO:2000680)
1.7 5.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.6 4.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.6 4.7 GO:1905005 regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
1.5 4.6 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.5 12.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.5 6.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
1.4 4.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.4 8.6 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.4 5.7 GO:0006842 tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746)
1.4 1.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
1.3 4.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.3 40.0 GO:0006270 DNA replication initiation(GO:0006270)
1.3 3.8 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
1.3 8.9 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
1.3 5.0 GO:0010288 response to lead ion(GO:0010288)
1.2 6.2 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
1.2 7.4 GO:0006344 maintenance of chromatin silencing(GO:0006344)
1.2 3.7 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.2 9.8 GO:0001675 acrosome assembly(GO:0001675)
1.2 12.1 GO:0090527 actin filament reorganization(GO:0090527)
1.2 6.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.2 5.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.2 4.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.2 12.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
1.1 3.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.1 4.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
1.1 7.8 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
1.1 4.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
1.1 3.3 GO:0086017 renin secretion into blood stream(GO:0002001) cell communication by chemical coupling(GO:0010643) Purkinje myocyte action potential(GO:0086017) regulation of renin secretion into blood stream(GO:1900133)
1.1 3.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.1 6.5 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
1.1 1.1 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
1.1 3.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.1 4.3 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
1.1 3.2 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.1 11.6 GO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
1.1 28.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
1.0 2.1 GO:2000224 testosterone biosynthetic process(GO:0061370) regulation of testosterone biosynthetic process(GO:2000224)
1.0 4.2 GO:0070829 heterochromatin maintenance(GO:0070829)
1.0 4.1 GO:1900145 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.0 3.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.0 4.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.0 1.0 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
1.0 3.9 GO:1904426 positive regulation of GTP binding(GO:1904426) regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
1.0 9.7 GO:0060235 lens induction in camera-type eye(GO:0060235)
1.0 8.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.0 4.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.0 2.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.9 11.3 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.9 2.8 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.9 12.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.9 2.7 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.9 2.7 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.9 4.5 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.9 7.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.9 2.7 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.9 10.8 GO:0019985 translesion synthesis(GO:0019985)
0.9 3.5 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.9 5.3 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.9 3.4 GO:0015871 choline transport(GO:0015871)
0.8 20.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.8 4.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.8 7.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.8 2.5 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.8 4.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.8 6.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.8 3.9 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.8 3.9 GO:1902570 protein localization to nucleolus(GO:1902570)
0.8 3.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.8 7.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.8 4.6 GO:0070836 caveola assembly(GO:0070836)
0.8 3.8 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.8 3.8 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.8 2.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.7 2.2 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.7 2.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.7 2.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.7 2.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.7 3.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.7 7.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.7 4.1 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.7 0.7 GO:0003149 membranous septum morphogenesis(GO:0003149)
0.7 8.8 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.7 3.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.7 1.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.7 13.8 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.7 3.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.6 10.4 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.6 0.6 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.6 3.9 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.6 1.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.6 1.9 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.6 6.3 GO:0048664 neuron fate determination(GO:0048664)
0.6 3.8 GO:0043586 tongue development(GO:0043586)
0.6 1.2 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.6 2.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.6 6.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.6 0.6 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.6 4.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.6 3.5 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.6 8.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.6 1.7 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.6 11.9 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.6 1.1 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.6 3.9 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.6 5.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.6 1.7 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.6 0.6 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.5 3.8 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.5 1.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.5 5.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.5 3.2 GO:0060736 prostate gland growth(GO:0060736)
0.5 2.1 GO:0034214 protein hexamerization(GO:0034214)
0.5 7.3 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.5 9.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.5 2.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.5 1.5 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.5 1.5 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.5 2.9 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.5 22.5 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.5 13.6 GO:0046677 response to antibiotic(GO:0046677)
0.5 6.3 GO:0001709 cell fate determination(GO:0001709)
0.5 1.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.5 4.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.5 3.2 GO:0097237 cellular response to toxic substance(GO:0097237)
0.5 6.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.4 1.8 GO:0009414 response to water deprivation(GO:0009414)
0.4 4.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.4 3.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.4 2.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 2.6 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.4 7.0 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.4 4.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4 3.0 GO:0018158 protein oxidation(GO:0018158)
0.4 2.2 GO:0060430 lung saccule development(GO:0060430)
0.4 0.9 GO:0042045 epithelial fluid transport(GO:0042045)
0.4 0.9 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.4 0.8 GO:2000018 regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020)
0.4 1.7 GO:0072235 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.4 3.3 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.4 1.2 GO:0019079 viral genome replication(GO:0019079)
0.4 6.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.4 1.2 GO:1905154 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154)
0.4 3.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 1.6 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.4 2.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.4 2.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.4 1.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.4 1.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.4 1.5 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.4 1.5 GO:0071139 resolution of recombination intermediates(GO:0071139)
0.4 2.9 GO:0046541 saliva secretion(GO:0046541)
0.4 4.7 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.4 1.8 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.4 1.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.4 0.7 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799)
0.4 1.8 GO:0042711 maternal behavior(GO:0042711)
0.4 10.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 1.8 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 1.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.3 2.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.3 3.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.3 1.0 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.3 1.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 7.2 GO:0015701 bicarbonate transport(GO:0015701)
0.3 3.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.3 1.7 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.3 4.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.3 3.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.3 0.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.3 0.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 1.7 GO:0001840 neural plate development(GO:0001840)
0.3 1.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.3 4.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.3 1.0 GO:0006116 NADH oxidation(GO:0006116)
0.3 1.9 GO:0007296 vitellogenesis(GO:0007296)
0.3 0.6 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.3 0.6 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534)
0.3 2.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3 3.7 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.3 1.2 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.3 2.1 GO:0008343 adult feeding behavior(GO:0008343)
0.3 0.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.3 2.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 1.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.3 6.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.3 0.3 GO:0097274 urea homeostasis(GO:0097274)
0.3 1.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.3 0.8 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.3 3.8 GO:0051602 response to electrical stimulus(GO:0051602)
0.3 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.3 7.5 GO:0048844 artery morphogenesis(GO:0048844)
0.3 1.3 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.3 1.9 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.3 2.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.3 8.1 GO:0007588 excretion(GO:0007588)
0.3 0.5 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.3 2.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 0.8 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.3 2.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.2 2.2 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.2 2.0 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.2 2.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.7 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.2 0.7 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.2 1.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 1.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 0.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2 0.7 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 2.5 GO:0010225 response to UV-C(GO:0010225)
0.2 1.8 GO:0006013 mannose metabolic process(GO:0006013)
0.2 2.0 GO:1903960 negative regulation of anion transmembrane transport(GO:1903960)
0.2 1.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2 0.9 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 5.3 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.2 1.1 GO:0019236 response to pheromone(GO:0019236)
0.2 13.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.2 0.6 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.2 1.3 GO:0001996 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993) positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of heart rate by epinephrine(GO:0003065) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.2 0.8 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.2 0.8 GO:0097298 regulation of nucleus size(GO:0097298)
0.2 1.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 3.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 1.6 GO:0001569 patterning of blood vessels(GO:0001569)
0.2 7.5 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.2 1.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 4.3 GO:0006379 mRNA cleavage(GO:0006379)
0.2 1.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 1.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 1.9 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.2 3.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 0.7 GO:0060459 left lung development(GO:0060459) endodermal digestive tract morphogenesis(GO:0061031)
0.2 4.8 GO:0001573 ganglioside metabolic process(GO:0001573)
0.2 2.3 GO:0051382 kinetochore assembly(GO:0051382)
0.2 1.9 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.3 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.2 1.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 1.9 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2 1.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 0.3 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.2 0.2 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.2 0.5 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286)
0.2 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.2 2.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 0.5 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.2 3.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 2.4 GO:0031297 replication fork processing(GO:0031297)
0.2 0.5 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 1.3 GO:0031053 primary miRNA processing(GO:0031053)
0.2 2.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 1.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.7 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 1.0 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.1 0.4 GO:0090370 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375) negative regulation of cholesterol efflux(GO:0090370)
0.1 2.1 GO:0030261 chromosome condensation(GO:0030261)
0.1 1.3 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.7 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.1 2.5 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 2.8 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 10.6 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.1 0.5 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.1 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 1.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 2.6 GO:0051084 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
0.1 12.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 1.7 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 4.1 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1 1.5 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.2 GO:0036166 phenotypic switching(GO:0036166)
0.1 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.3 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 0.4 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.1 1.6 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.1 0.9 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.1 1.2 GO:0046782 regulation of viral transcription(GO:0046782)
0.1 2.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.1 2.6 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.2 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.9 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.3 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.3 GO:0048665 neuron fate specification(GO:0048665)
0.1 2.5 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.5 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.8 GO:0030728 ovulation(GO:0030728)
0.1 1.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.9 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 2.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 4.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 3.2 GO:0009168 purine nucleoside monophosphate biosynthetic process(GO:0009127) purine ribonucleoside monophosphate biosynthetic process(GO:0009168)
0.1 1.0 GO:0032479 regulation of type I interferon production(GO:0032479) interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648)
0.1 1.0 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 1.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 2.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.5 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 3.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 1.0 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 2.7 GO:0001885 endothelial cell development(GO:0001885)
0.1 0.1 GO:0046851 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.1 1.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.7 GO:0099625 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 1.9 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 2.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 1.4 GO:0001947 heart looping(GO:0001947)
0.1 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 1.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.8 GO:0050892 intestinal absorption(GO:0050892)
0.1 0.5 GO:0099515 actin filament-based transport(GO:0099515)
0.1 0.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 1.3 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.8 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.5 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 7.3 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.3 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.5 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 1.5 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 1.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 3.2 GO:0048864 stem cell development(GO:0048864)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 2.1 GO:0048863 stem cell differentiation(GO:0048863)
0.0 0.6 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.2 GO:0015675 nickel cation transport(GO:0015675)
0.0 0.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 3.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 1.9 GO:0007601 visual perception(GO:0007601)
0.0 1.2 GO:0048066 developmental pigmentation(GO:0048066)
0.0 0.5 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 1.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 2.2 GO:0045137 development of primary sexual characteristics(GO:0045137)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.5 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.8 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.0 GO:0044065 regulation of respiratory gaseous exchange by neurological system process(GO:0002087) regulation of respiratory system process(GO:0044065)
0.0 0.5 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.6 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0035272 exocrine system development(GO:0035272)
0.0 0.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.6 GO:0009267 cellular response to starvation(GO:0009267)
0.0 1.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.6 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 26.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
4.0 52.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
3.3 9.8 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
2.4 7.3 GO:0033186 CAF-1 complex(GO:0033186)
2.0 5.9 GO:0000785 chromatin(GO:0000785)
2.0 11.8 GO:0044294 dendritic growth cone(GO:0044294)
1.9 7.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.7 11.9 GO:0001740 Barr body(GO:0001740)
1.6 7.8 GO:0044301 climbing fiber(GO:0044301)
1.4 4.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.3 6.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
1.3 3.8 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
1.2 18.0 GO:0042555 MCM complex(GO:0042555)
1.1 10.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
1.1 3.4 GO:0014802 terminal cisterna(GO:0014802)
1.1 3.4 GO:0018444 translation release factor complex(GO:0018444)
1.0 6.1 GO:0005663 DNA replication factor C complex(GO:0005663)
1.0 3.9 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.9 5.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.9 2.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.9 4.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.8 5.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.8 2.5 GO:0005787 signal peptidase complex(GO:0005787)
0.8 4.1 GO:0030056 hemidesmosome(GO:0030056)
0.8 5.6 GO:0097452 GAIT complex(GO:0097452)
0.8 17.8 GO:0001741 XY body(GO:0001741)
0.8 15.8 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.7 10.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.7 2.1 GO:0005899 insulin receptor complex(GO:0005899)
0.7 10.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.7 2.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.6 3.9 GO:0000235 astral microtubule(GO:0000235)
0.6 3.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.6 10.7 GO:0071564 npBAF complex(GO:0071564)
0.6 4.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.6 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.6 7.8 GO:0097470 ribbon synapse(GO:0097470)
0.6 12.5 GO:0030894 replisome(GO:0030894)
0.6 1.7 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.6 3.4 GO:0000796 condensin complex(GO:0000796)
0.5 20.9 GO:0005657 replication fork(GO:0005657)
0.5 7.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 3.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.5 4.3 GO:0005916 fascia adherens(GO:0005916)
0.4 4.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.4 2.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 20.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 1.3 GO:0034457 Mpp10 complex(GO:0034457)
0.4 1.2 GO:1990423 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.4 4.3 GO:0005915 zonula adherens(GO:0005915) flotillin complex(GO:0016600)
0.4 6.2 GO:0005614 interstitial matrix(GO:0005614)
0.4 1.9 GO:0001652 granular component(GO:0001652)
0.4 4.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 4.6 GO:0005922 connexon complex(GO:0005922)
0.4 3.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 3.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 1.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.3 1.5 GO:0030689 Noc complex(GO:0030689)
0.3 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.3 4.5 GO:0002080 acrosomal membrane(GO:0002080)
0.3 1.9 GO:0005638 lamin filament(GO:0005638)
0.3 3.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.3 36.6 GO:0005884 actin filament(GO:0005884)
0.3 1.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.3 2.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 7.4 GO:0051233 spindle midzone(GO:0051233)
0.2 1.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 1.2 GO:0098536 deuterosome(GO:0098536)
0.2 3.8 GO:0016580 Sin3 complex(GO:0016580)
0.2 15.9 GO:0031526 brush border membrane(GO:0031526)
0.2 3.0 GO:0031011 Ino80 complex(GO:0031011)
0.2 14.7 GO:0005844 polysome(GO:0005844)
0.2 0.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 1.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 2.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 1.9 GO:0034709 methylosome(GO:0034709)
0.2 1.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 2.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 14.6 GO:0032432 actin filament bundle(GO:0032432)
0.2 2.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 0.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.9 GO:0000974 Prp19 complex(GO:0000974)
0.2 1.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 2.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 1.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 6.3 GO:0016592 mediator complex(GO:0016592)
0.2 3.2 GO:0045120 pronucleus(GO:0045120)
0.2 0.8 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 0.9 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 1.8 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.0 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.8 GO:0000938 GARP complex(GO:0000938)
0.1 1.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.5 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.3 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 3.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.0 GO:0001650 fibrillar center(GO:0001650)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 6.6 GO:0005581 collagen trimer(GO:0005581)
0.1 6.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.3 GO:0071014 U2-type post-mRNA release spliceosomal complex(GO:0071008) post-mRNA release spliceosomal complex(GO:0071014)
0.1 2.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 43.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 2.4 GO:1990391 DNA repair complex(GO:1990391)
0.1 1.1 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.6 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.7 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 10.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 3.9 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 6.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 4.1 GO:0005902 microvillus(GO:0005902)
0.1 2.8 GO:0001772 immunological synapse(GO:0001772)
0.1 1.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.3 GO:0097413 Lewy body(GO:0097413)
0.1 4.0 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.1 1.4 GO:0032279 asymmetric synapse(GO:0032279)
0.1 17.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.3 GO:0005605 basal lamina(GO:0005605)
0.1 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 3.4 GO:0031985 Golgi cisterna(GO:0031985)
0.1 3.5 GO:0070160 occluding junction(GO:0070160)
0.1 1.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.4 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.1 0.9 GO:0032993 protein-DNA complex(GO:0032993)
0.1 2.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.1 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.4 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 2.9 GO:0005903 brush border(GO:0005903)
0.1 1.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 34.6 GO:0005730 nucleolus(GO:0005730)
0.0 0.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0070161 adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.0 0.1 GO:0070449 elongin complex(GO:0070449)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 2.6 GO:0000502 proteasome complex(GO:0000502)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 2.4 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 1.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 2.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.5 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 4.4 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 60.6 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 26.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
4.3 12.9 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
4.2 12.5 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
3.9 11.8 GO:0097108 hedgehog family protein binding(GO:0097108)
3.8 22.8 GO:0043426 MRF binding(GO:0043426)
3.4 13.7 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
3.3 49.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
3.2 9.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
2.6 10.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
2.4 7.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
2.4 19.1 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
2.3 9.1 GO:0005113 patched binding(GO:0005113)
2.1 14.6 GO:0034056 estrogen response element binding(GO:0034056)
2.1 12.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.9 5.8 GO:0035939 microsatellite binding(GO:0035939)
1.9 5.7 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
1.7 6.7 GO:0043515 kinetochore binding(GO:0043515)
1.7 13.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.6 9.8 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
1.5 9.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.5 5.9 GO:0048408 epidermal growth factor binding(GO:0048408)
1.4 14.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.4 4.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
1.4 12.7 GO:0008420 CTD phosphatase activity(GO:0008420)
1.4 12.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.3 4.0 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
1.3 3.8 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
1.2 4.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.1 3.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.1 36.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.0 22.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.0 10.3 GO:0070700 BMP receptor binding(GO:0070700)
1.0 5.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.9 10.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.9 4.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.9 0.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.9 7.0 GO:0043495 protein anchor(GO:0043495)
0.9 3.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.8 9.3 GO:0030957 Tat protein binding(GO:0030957)
0.8 12.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.8 5.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.8 4.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.8 4.7 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.8 3.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.8 3.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.7 2.2 GO:0070052 collagen V binding(GO:0070052)
0.7 2.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 5.8 GO:0046790 virion binding(GO:0046790)
0.7 4.3 GO:0017166 vinculin binding(GO:0017166)
0.7 4.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.7 22.3 GO:0071837 HMG box domain binding(GO:0071837)
0.7 1.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.7 0.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.7 4.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.7 3.9 GO:0015265 urea channel activity(GO:0015265)
0.6 7.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.6 4.4 GO:1990188 euchromatin binding(GO:1990188)
0.6 6.9 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.6 2.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.6 17.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.6 4.9 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.6 7.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.6 2.3 GO:0004111 creatine kinase activity(GO:0004111)
0.6 4.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.6 6.3 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.6 14.8 GO:0008432 JUN kinase binding(GO:0008432)
0.6 11.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.6 9.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.6 2.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.5 3.3 GO:0043237 laminin-1 binding(GO:0043237)
0.5 1.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.5 4.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 2.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.5 3.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 2.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 1.6 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.5 2.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.5 1.5 GO:0030362 protein phosphatase type 4 regulator activity(GO:0030362)
0.5 1.5 GO:0030620 U2 snRNA binding(GO:0030620)
0.5 5.0 GO:0050692 DBD domain binding(GO:0050692)
0.5 6.4 GO:0030547 receptor inhibitor activity(GO:0030547)
0.5 4.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 5.1 GO:0005243 gap junction channel activity(GO:0005243)
0.4 3.8 GO:0034711 inhibin binding(GO:0034711)
0.4 4.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.4 2.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.4 3.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.4 3.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 2.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.4 5.9 GO:0031005 filamin binding(GO:0031005)
0.4 19.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 2.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.4 40.0 GO:0005178 integrin binding(GO:0005178)
0.4 1.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.4 1.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.4 2.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 4.4 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 6.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 3.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.4 1.1 GO:0051425 PTB domain binding(GO:0051425)
0.3 5.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.3 4.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.3 6.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 7.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 2.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.3 0.6 GO:0043398 HLH domain binding(GO:0043398)
0.3 8.0 GO:0070888 E-box binding(GO:0070888)
0.3 5.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3 14.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 5.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 0.9 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.3 12.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.3 2.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 2.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 6.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 0.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 7.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 3.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 12.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 3.8 GO:0015026 coreceptor activity(GO:0015026)
0.3 10.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 2.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.3 6.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.3 3.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 3.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 2.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 4.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.3 7.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 1.4 GO:0070697 activin receptor binding(GO:0070697)
0.3 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 5.7 GO:0005112 Notch binding(GO:0005112)
0.3 1.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.3 1.8 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.3 3.1 GO:0031996 thioesterase binding(GO:0031996)
0.3 2.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 2.7 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 3.9 GO:0001968 fibronectin binding(GO:0001968)
0.2 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 1.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.2 14.1 GO:0003678 DNA helicase activity(GO:0003678)
0.2 0.7 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.2 13.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 7.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 2.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 1.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 3.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2 1.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 4.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 2.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.8 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.2 1.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.2 GO:0008494 translation activator activity(GO:0008494)
0.2 2.5 GO:0048038 quinone binding(GO:0048038)
0.2 8.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.2 14.1 GO:0008083 growth factor activity(GO:0008083)
0.2 3.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.2 2.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 10.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.2 15.7 GO:0001047 core promoter binding(GO:0001047)
0.2 3.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 0.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 5.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 3.4 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2 47.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.2 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 0.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 6.0 GO:0005109 frizzled binding(GO:0005109)
0.2 7.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 0.3 GO:0031493 nucleosomal histone binding(GO:0031493)
0.2 5.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 4.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 0.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 1.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.3 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.1 2.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 2.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 6.4 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.1 GO:0008483 transaminase activity(GO:0008483)
0.1 2.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 2.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.3 GO:0019002 GMP binding(GO:0019002)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 11.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 2.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 1.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.2 GO:0005537 mannose binding(GO:0005537)
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 15.0 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1 1.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 3.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 3.4 GO:0005179 hormone activity(GO:0005179)
0.1 3.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 2.3 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 2.6 GO:0035064 methylated histone binding(GO:0035064)
0.1 2.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 4.8 GO:0042393 histone binding(GO:0042393)
0.1 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.6 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.9 GO:0005521 lamin binding(GO:0005521)
0.1 2.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.5 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.1 GO:0019956 chemokine binding(GO:0019956)
0.1 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 2.7 GO:0005125 cytokine activity(GO:0005125)
0.0 7.8 GO:0003729 mRNA binding(GO:0003729)
0.0 1.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.5 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 3.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.5 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 5.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.1 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)