Motif ID: E2f7
Z-value: 1.603
Transcription factors associated with E2f7:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
E2f7 | ENSMUSG00000020185.10 | E2f7 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
E2f7 | mm10_v2_chr10_+_110745433_110745572 | 0.81 | 9.9e-18 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.9 | 29.4 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
4.1 | 16.4 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
3.2 | 32.3 | GO:0009186 | deoxyribonucleoside diphosphate metabolic process(GO:0009186) |
2.3 | 11.5 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
2.0 | 15.6 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
1.9 | 17.1 | GO:1901970 | positive regulation of mitotic sister chromatid separation(GO:1901970) |
1.8 | 16.0 | GO:0090166 | Golgi disassembly(GO:0090166) |
1.5 | 10.3 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
1.4 | 4.2 | GO:0071139 | resolution of recombination intermediates(GO:0071139) |
1.3 | 6.3 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
1.2 | 3.7 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
1.2 | 3.7 | GO:0040009 | regulation of growth rate(GO:0040009) protein poly-ADP-ribosylation(GO:0070212) |
1.2 | 16.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
1.2 | 7.1 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
1.2 | 5.8 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
1.1 | 6.7 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
1.0 | 2.9 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
1.0 | 4.8 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
0.9 | 3.4 | GO:1904008 | response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009) |
0.8 | 2.5 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.8 | 3.3 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
0.8 | 9.0 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
0.8 | 2.4 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.8 | 3.1 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
0.7 | 10.3 | GO:0051382 | kinetochore assembly(GO:0051382) |
0.7 | 2.0 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
0.6 | 11.4 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224) |
0.6 | 2.9 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
0.6 | 13.2 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.5 | 9.2 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.4 | 5.7 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.4 | 5.2 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.4 | 1.6 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.4 | 3.4 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.4 | 7.8 | GO:0021924 | cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930) |
0.4 | 11.1 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.4 | 8.5 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
0.4 | 1.4 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
0.3 | 2.0 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.3 | 9.7 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.3 | 12.6 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.3 | 2.7 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.2 | 1.4 | GO:1903887 | motile primary cilium assembly(GO:1903887) protein localization to ciliary transition zone(GO:1904491) |
0.2 | 7.0 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.2 | 1.2 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.2 | 1.3 | GO:0009146 | purine nucleoside triphosphate catabolic process(GO:0009146) |
0.2 | 0.7 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.2 | 1.2 | GO:0034379 | very-low-density lipoprotein particle assembly(GO:0034379) |
0.2 | 6.3 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
0.1 | 2.2 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
0.1 | 7.3 | GO:0019915 | lipid storage(GO:0019915) |
0.1 | 2.0 | GO:0043486 | histone exchange(GO:0043486) |
0.1 | 4.4 | GO:0034605 | cellular response to heat(GO:0034605) |
0.1 | 5.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.1 | 2.1 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
0.1 | 2.2 | GO:0003351 | epithelial cilium movement(GO:0003351) |
0.1 | 0.6 | GO:0071499 | response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499) |
0.1 | 4.5 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
0.1 | 0.6 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
0.1 | 1.3 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) protein heterotrimerization(GO:0070208) |
0.0 | 5.1 | GO:0030010 | establishment of cell polarity(GO:0030010) |
0.0 | 1.2 | GO:0006611 | protein export from nucleus(GO:0006611) |
0.0 | 24.1 | GO:0006915 | apoptotic process(GO:0006915) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.5 | 32.3 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
3.2 | 25.3 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
2.7 | 29.4 | GO:0005915 | zonula adherens(GO:0005915) |
2.2 | 6.7 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
1.6 | 4.8 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
1.3 | 18.6 | GO:0042555 | MCM complex(GO:0042555) |
0.7 | 2.7 | GO:0032021 | NELF complex(GO:0032021) |
0.7 | 9.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.6 | 3.1 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476) |
0.6 | 2.9 | GO:0001651 | dense fibrillar component(GO:0001651) granular component(GO:0001652) |
0.6 | 7.0 | GO:0000124 | SAGA complex(GO:0000124) |
0.5 | 2.0 | GO:0072588 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA telomerase RNP complex(GO:0090661) |
0.5 | 3.4 | GO:0005638 | lamin filament(GO:0005638) |
0.5 | 16.5 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.5 | 36.9 | GO:0072686 | mitotic spindle(GO:0072686) |
0.3 | 3.7 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.3 | 3.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.2 | 1.3 | GO:0090543 | Flemming body(GO:0090543) |
0.2 | 4.4 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.2 | 12.8 | GO:0000922 | spindle pole(GO:0000922) |
0.1 | 1.7 | GO:0001527 | microfibril(GO:0001527) |
0.1 | 0.5 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
0.1 | 5.3 | GO:0000786 | nucleosome(GO:0000786) |
0.1 | 7.3 | GO:0005811 | lipid particle(GO:0005811) |
0.1 | 1.4 | GO:0036038 | MKS complex(GO:0036038) |
0.1 | 28.6 | GO:0005667 | transcription factor complex(GO:0005667) |
0.1 | 0.8 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 4.5 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 5.7 | GO:0000776 | kinetochore(GO:0000776) |
0.0 | 0.9 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 1.6 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 1.2 | GO:0005814 | centriole(GO:0005814) |
0.0 | 12.3 | GO:0005730 | nucleolus(GO:0005730) |
0.0 | 3.3 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 0.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.5 | 32.3 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
2.9 | 11.5 | GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
2.8 | 22.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
2.7 | 32.1 | GO:0070097 | delta-catenin binding(GO:0070097) |
2.6 | 15.6 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
2.0 | 7.8 | GO:0043515 | kinetochore binding(GO:0043515) |
1.4 | 8.7 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
1.3 | 1.3 | GO:0036222 | XTP diphosphatase activity(GO:0036222) |
1.1 | 3.4 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
1.0 | 19.2 | GO:0035173 | histone kinase activity(GO:0035173) |
1.0 | 4.8 | GO:0070883 | importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883) |
1.0 | 6.7 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
0.8 | 8.5 | GO:0030957 | Tat protein binding(GO:0030957) |
0.7 | 3.7 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.7 | 12.7 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.6 | 3.7 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.6 | 2.4 | GO:0019808 | polyamine binding(GO:0019808) |
0.5 | 2.0 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.4 | 2.9 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.3 | 2.9 | GO:0001224 | RNA polymerase II transcription cofactor binding(GO:0001224) |
0.3 | 1.3 | GO:0051425 | PTB domain binding(GO:0051425) |
0.3 | 9.6 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.2 | 1.4 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.2 | 2.1 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.2 | 2.5 | GO:0048038 | quinone binding(GO:0048038) |
0.2 | 14.2 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.2 | 1.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.2 | 7.3 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
0.2 | 13.0 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.2 | 0.5 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.1 | 3.4 | GO:0043274 | phospholipase binding(GO:0043274) |
0.1 | 7.1 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.1 | 0.5 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.1 | 5.3 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.1 | 17.6 | GO:0001047 | core promoter binding(GO:0001047) |
0.1 | 0.8 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.1 | 8.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.1 | 4.4 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
0.1 | 9.6 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 3.3 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.0 | 6.6 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 9.0 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.0 | 1.2 | GO:0004772 | sterol O-acyltransferase activity(GO:0004772) |
0.0 | 2.0 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 7.1 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 1.0 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 4.5 | GO:0022832 | voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832) |
0.0 | 1.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 7.0 | GO:0003682 | chromatin binding(GO:0003682) |