Motif ID: Ebf3

Z-value: 1.209


Transcription factors associated with Ebf3:

Gene SymbolEntrez IDGene Name
Ebf3 ENSMUSG00000010476.7 Ebf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ebf3mm10_v2_chr7_-_137314394_137314445-0.103.9e-01Click!


Activity profile for motif Ebf3.

activity profile for motif Ebf3


Sorted Z-values histogram for motif Ebf3

Sorted Z-values for motif Ebf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ebf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66812593 23.212 ENSMUST00000100572.3
 Sla
src-like adaptor
chr5_+_117781017 16.165 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr1_-_56969827 14.522 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr1_-_56969864 14.360 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr11_-_98329641 12.010 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr7_+_123982799 11.344 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr11_+_104231390 10.926 ENSMUST00000106992.3
 Mapt
microtubule-associated protein tau
chr11_+_104231573 10.874 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
 Mapt


microtubule-associated protein tau


chr11_+_104231515 10.457 ENSMUST00000106993.3
 Mapt
microtubule-associated protein tau
chr2_+_55437100 10.445 ENSMUST00000112633.2
ENSMUST00000112632.1
 Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr11_+_104231465 9.964 ENSMUST00000145227.1
 Mapt
microtubule-associated protein tau
chr18_-_31447383 9.625 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr4_-_129121234 9.537 ENSMUST00000030572.3
 Hpca
hippocalcin
chr6_-_32588192 9.320 ENSMUST00000115096.2
 Plxna4
plexin A4
chr4_-_129121699 9.060 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
 Hpca


hippocalcin


chr1_-_173367638 9.018 ENSMUST00000005470.4
ENSMUST00000111220.1
 Cadm3

cell adhesion molecule 3

chr7_-_4546567 8.743 ENSMUST00000065957.5
 Syt5
synaptotagmin V
chr1_-_154725920 8.383 ENSMUST00000004214.8
 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr5_-_139129662 8.301 ENSMUST00000026973.7
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr1_-_193370225 8.019 ENSMUST00000169907.1
 Camk1g
calcium/calmodulin-dependent protein kinase I gamma

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 140 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 42.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
1.8 28.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
6.2 18.6 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
4.0 16.2 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
1.3 16.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.6 15.7 GO:0010107 potassium ion import(GO:0010107)
1.6 12.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
4.0 12.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 10.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
1.2 9.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
2.3 9.3 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 9.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.7 8.4 GO:0090273 regulation of somatostatin secretion(GO:0090273)
1.3 7.9 GO:0072318 clathrin coat disassembly(GO:0072318)
1.2 7.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.2 7.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.3 6.7 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
1.6 6.5 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.8 6.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 6.3 GO:0050832 defense response to fungus(GO:0050832)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.2 42.2 GO:0045298 tubulin complex(GO:0045298)
0.0 31.5 GO:0005768 endosome(GO:0005768)
0.2 23.3 GO:0000118 histone deacetylase complex(GO:0000118)
1.9 18.6 GO:0044327 dendritic spine head(GO:0044327)
1.2 18.4 GO:0031045 dense core granule(GO:0031045)
0.4 17.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.5 16.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.2 16.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 13.5 GO:0030315 T-tubule(GO:0030315)
0.2 12.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.8 10.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 10.0 GO:0030425 dendrite(GO:0030425)
0.8 9.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 9.0 GO:0031941 filamentous actin(GO:0031941)
0.2 7.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 7.3 GO:0005913 cell-cell adherens junction(GO:0005913)
2.2 6.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 6.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.3 6.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 6.0 GO:0060077 inhibitory synapse(GO:0060077)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 36.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.4 16.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
5.4 16.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.5 16.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
3.1 15.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.0 13.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 9.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.7 9.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 8.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 8.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 8.3 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.4 7.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
1.2 7.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.4 7.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 7.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 6.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.5 6.6 GO:0031005 filamin binding(GO:0031005)
1.3 6.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.1 6.3 GO:0005042 netrin receptor activity(GO:0005042)
0.8 6.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)