Motif ID: Egr3
Z-value: 0.627
Transcription factors associated with Egr3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Egr3 | ENSMUSG00000033730.3 | Egr3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Egr3 | mm10_v2_chr14_+_70077375_70077445 | -0.09 | 4.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 11.5 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.7 | 2.1 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
0.6 | 1.7 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
0.5 | 2.4 | GO:0046684 | response to pyrethroid(GO:0046684) |
0.4 | 3.5 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.4 | 1.4 | GO:0061626 | pharyngeal arch artery morphogenesis(GO:0061626) |
0.3 | 1.6 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
0.3 | 2.1 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.3 | 0.9 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
0.3 | 1.7 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.3 | 0.8 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
0.2 | 1.4 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.1 | 2.8 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
0.1 | 1.2 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.1 | 0.3 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
0.1 | 0.5 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
0.1 | 0.8 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.1 | 1.5 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
0.1 | 0.5 | GO:0045054 | constitutive secretory pathway(GO:0045054) |
0.1 | 2.6 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.1 | 0.6 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
0.1 | 5.8 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
0.1 | 0.9 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.1 | 0.4 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.1 | 4.0 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.1 | 2.4 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
0.1 | 1.1 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
0.1 | 1.1 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
0.0 | 1.3 | GO:0072348 | sulfur compound transport(GO:0072348) |
0.0 | 0.1 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
0.0 | 2.0 | GO:0035640 | exploration behavior(GO:0035640) |
0.0 | 0.2 | GO:0000189 | MAPK import into nucleus(GO:0000189) response to epidermal growth factor(GO:0070849) |
0.0 | 0.5 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 1.0 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 1.0 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.0 | 0.4 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.0 | 0.1 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) |
0.0 | 1.7 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.0 | 0.4 | GO:0043486 | histone exchange(GO:0043486) |
0.0 | 1.0 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
0.0 | 0.2 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.0 | 0.3 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.0 | 0.6 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.1 | GO:0060613 | fat pad development(GO:0060613) |
0.0 | 0.5 | GO:0032456 | endocytic recycling(GO:0032456) |
0.0 | 0.5 | GO:0008214 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) |
0.0 | 0.0 | GO:0043046 | DNA methylation involved in gamete generation(GO:0043046) |
0.0 | 2.3 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
0.0 | 1.3 | GO:0098792 | xenophagy(GO:0098792) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 11.5 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.3 | 3.5 | GO:0031209 | SCAR complex(GO:0031209) |
0.2 | 1.0 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.2 | 1.4 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 2.4 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
0.1 | 0.4 | GO:0031417 | NatC complex(GO:0031417) |
0.1 | 0.5 | GO:1990745 | EARP complex(GO:1990745) |
0.1 | 0.9 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 1.5 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
0.1 | 0.3 | GO:0042583 | chromaffin granule(GO:0042583) |
0.0 | 0.9 | GO:0031430 | M band(GO:0031430) |
0.0 | 0.5 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 1.1 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 3.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.4 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 1.8 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 1.5 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.3 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.0 | 0.2 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 0.5 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 1.7 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
0.0 | 0.5 | GO:0031201 | SNARE complex(GO:0031201) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.8 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.4 | 12.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.3 | 5.8 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.2 | 1.5 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
0.2 | 2.5 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.1 | 1.0 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.1 | 1.7 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 6.8 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.1 | 1.4 | GO:0030957 | Tat protein binding(GO:0030957) |
0.1 | 2.4 | GO:0031402 | sodium ion binding(GO:0031402) |
0.1 | 1.1 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
0.1 | 2.9 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 1.7 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.1 | 1.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 2.6 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.1 | 2.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 1.3 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.1 | 0.9 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
0.1 | 3.5 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.1 | 0.3 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.1 | 0.2 | GO:2001069 | glycogen binding(GO:2001069) |
0.0 | 0.1 | GO:0004568 | chitinase activity(GO:0004568) |
0.0 | 1.4 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
0.0 | 0.3 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.0 | 0.8 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.5 | GO:0051723 | protein methylesterase activity(GO:0051723) |
0.0 | 0.6 | GO:0032183 | SUMO binding(GO:0032183) |
0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.3 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
0.0 | 2.3 | GO:0002020 | protease binding(GO:0002020) |
0.0 | 0.9 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.0 | 0.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.2 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.9 | GO:0051219 | phosphoprotein binding(GO:0051219) |