Motif ID: Elf1_Elf2_Etv2_Elf4

Z-value: 2.317

Transcription factors associated with Elf1_Elf2_Etv2_Elf4:

Gene SymbolEntrez IDGene Name
Elf1 ENSMUSG00000036461.9 Elf1
Elf2 ENSMUSG00000037174.12 Elf2
Elf4 ENSMUSG00000031103.6 Elf4
Etv2 ENSMUSG00000006311.8 Etv2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf4mm10_v2_chrX_-_48454152_484541930.491.4e-05Click!
Elf2mm10_v2_chr3_-_51340628_51340681-0.353.2e-03Click!
Elf1mm10_v2_chr14_+_79481164_79481194-0.191.1e-01Click!


Activity profile for motif Elf1_Elf2_Etv2_Elf4.

activity profile for motif Elf1_Elf2_Etv2_Elf4


Sorted Z-values histogram for motif Elf1_Elf2_Etv2_Elf4

Sorted Z-values for motif Elf1_Elf2_Etv2_Elf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf1_Elf2_Etv2_Elf4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 24.420 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_+_5845243 22.880 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr7_-_127042420 21.170 ENSMUST00000032915.6
 Kif22
kinesin family member 22
chr11_-_94653964 20.841 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr19_+_6084983 20.416 ENSMUST00000025704.2
 Cdca5
cell division cycle associated 5
chr16_-_18811972 19.935 ENSMUST00000000028.7
ENSMUST00000115585.1
 Cdc45

cell division cycle 45

chr1_+_84839833 17.457 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr11_-_12037391 16.590 ENSMUST00000093321.5
 Grb10
growth factor receptor bound protein 10
chr2_-_5012716 16.482 ENSMUST00000027980.7
 Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr3_-_89418287 16.146 ENSMUST00000029679.3
 Cks1b
CDC28 protein kinase 1b
chr2_-_156839790 15.533 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
 Gm14230


predicted gene 14230


chr2_+_156840077 15.301 ENSMUST00000081335.6
ENSMUST00000073352.3
 Tgif2

TGFB-induced factor homeobox 2

chr19_-_9899450 15.237 ENSMUST00000025562.7
 Incenp
inner centromere protein
chrX_+_100625737 14.952 ENSMUST00000048962.3
 Kif4
kinesin family member 4
chr2_+_105682463 14.788 ENSMUST00000140173.1
ENSMUST00000135412.1
ENSMUST00000138365.1
ENSMUST00000145744.1
 Pax6



paired box gene 6



chr16_-_22161450 14.065 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr9_-_57836706 14.043 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
 Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr16_+_48994185 13.969 ENSMUST00000117994.1
ENSMUST00000048374.5
 C330027C09Rik

RIKEN cDNA C330027C09 gene

chr2_+_5845017 13.918 ENSMUST00000026927.3
ENSMUST00000179748.1
 Nudt5

nudix (nucleoside diphosphate linked moiety X)-type motif 5

chr4_-_118437331 13.907 ENSMUST00000006565.6
 Cdc20
cell division cycle 20

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,042 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 192.2 GO:0008380 RNA splicing(GO:0008380)
0.9 69.9 GO:0006413 translational initiation(GO:0006413)
1.7 64.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
2.1 63.0 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
2.3 56.3 GO:0006270 DNA replication initiation(GO:0006270)
1.6 56.2 GO:0051310 metaphase plate congression(GO:0051310)
2.6 51.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
1.4 47.0 GO:0006284 base-excision repair(GO:0006284)
1.6 42.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 40.4 GO:0006412 translation(GO:0006412)
0.7 40.0 GO:0051028 mRNA transport(GO:0051028)
0.3 38.1 GO:0008360 regulation of cell shape(GO:0008360)
5.9 35.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.3 33.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.7 33.0 GO:0002181 cytoplasmic translation(GO:0002181)
1.3 32.8 GO:0030488 tRNA methylation(GO:0030488)
0.9 32.7 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
4.4 31.0 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
2.6 31.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
3.6 28.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 378 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 228.0 GO:0005730 nucleolus(GO:0005730)
1.9 137.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.3 109.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 99.9 GO:0005654 nucleoplasm(GO:0005654)
0.0 98.8 GO:0005634 nucleus(GO:0005634)
2.0 97.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
1.1 70.7 GO:0072686 mitotic spindle(GO:0072686)
0.2 66.7 GO:0005667 transcription factor complex(GO:0005667)
0.7 66.3 GO:0005681 spliceosomal complex(GO:0005681)
0.2 59.2 GO:0000785 chromatin(GO:0000785)
4.1 49.6 GO:0005687 U4 snRNP(GO:0005687)
1.0 41.2 GO:0015934 large ribosomal subunit(GO:0015934)
2.7 40.4 GO:0042555 MCM complex(GO:0042555)
0.6 38.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
5.1 35.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
2.4 33.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.8 32.1 GO:0008180 COP9 signalosome(GO:0008180)
1.2 30.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.5 30.9 GO:0005814 centriole(GO:0005814)
0.6 30.8 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 594 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 195.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 148.7 GO:0044822 poly(A) RNA binding(GO:0044822)
1.0 84.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
1.2 78.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 66.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.2 61.7 GO:0019843 rRNA binding(GO:0019843)
7.2 57.8 GO:0003688 DNA replication origin binding(GO:0003688)
1.1 52.6 GO:0000049 tRNA binding(GO:0000049)
0.7 51.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.8 50.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
2.1 47.1 GO:0017025 TBP-class protein binding(GO:0017025)
3.0 45.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 43.4 GO:0000975 regulatory region DNA binding(GO:0000975)
0.8 40.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
5.0 40.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.6 38.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
4.2 38.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
4.2 37.6 GO:1990446 U1 snRNP binding(GO:1990446)
0.8 36.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 31.4 GO:0051015 actin filament binding(GO:0051015)