Motif ID: Elf3

Z-value: 1.138


Transcription factors associated with Elf3:

Gene SymbolEntrez IDGene Name
Elf3 ENSMUSG00000003051.7 Elf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.651.3e-09Click!


Activity profile for motif Elf3.

activity profile for motif Elf3


Sorted Z-values histogram for motif Elf3

Sorted Z-values for motif Elf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_35049966 13.005 ENSMUST00000007257.9
 Clic1
chloride intracellular channel 1
chr14_-_70207637 12.485 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr11_-_55419898 11.339 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr11_+_115163333 11.062 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr6_-_146502141 10.926 ENSMUST00000079573.6
ENSMUST00000139732.1
 Itpr2

inositol 1,4,5-triphosphate receptor 2

chr15_+_79516396 9.415 ENSMUST00000010974.7
 Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr18_+_56432116 8.987 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr11_+_78324200 8.583 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr19_-_50678642 8.534 ENSMUST00000072685.6
ENSMUST00000164039.2
 Sorcs1

VPS10 domain receptor protein SORCS 1

chr12_-_65172560 8.275 ENSMUST00000052201.8
 Mis18bp1
MIS18 binding protein 1
chr10_-_83648713 8.073 ENSMUST00000020500.7
 Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr19_-_50678485 7.978 ENSMUST00000111756.3
 Sorcs1
VPS10 domain receptor protein SORCS 1
chr19_+_25406661 7.886 ENSMUST00000146647.1
 Kank1
KN motif and ankyrin repeat domains 1
chr6_+_15720654 7.618 ENSMUST00000101663.3
 Mdfic
MyoD family inhibitor domain containing
chr7_+_101378183 7.489 ENSMUST00000084895.5
 Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_-_102250086 7.294 ENSMUST00000106923.1
ENSMUST00000098230.4
 Rhog

ras homolog gene family, member G

chr16_+_62854299 7.036 ENSMUST00000023629.8
 Pros1
protein S (alpha)
chr19_+_16435616 6.687 ENSMUST00000025602.2
 Gna14
guanine nucleotide binding protein, alpha 14
chr14_-_54577578 6.668 ENSMUST00000054487.8
 Ajuba
ajuba LIM protein
chr6_+_15721087 6.648 ENSMUST00000120512.1
 Mdfic
MyoD family inhibitor domain containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 136 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 20.1 GO:0050434 positive regulation of viral transcription(GO:0050434)
2.3 16.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.4 14.8 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 13.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 12.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
3.1 12.4 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
3.8 11.4 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.4 11.3 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
3.7 11.1 GO:0042939 renal sodium ion transport(GO:0003096) glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 10.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
1.3 9.4 GO:0006621 protein retention in ER lumen(GO:0006621)
1.5 8.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.9 8.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.7 8.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.0 7.9 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
2.4 7.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.4 7.3 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.8 7.0 GO:0042730 fibrinolysis(GO:0042730)
1.7 6.9 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
1.3 6.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 32.5 GO:0005925 focal adhesion(GO:0005925)
0.8 16.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 13.1 GO:0034707 chloride channel complex(GO:0034707)
0.5 12.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 11.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
2.8 11.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
2.2 11.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 10.9 GO:0072562 blood microparticle(GO:0072562)
1.4 10.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 9.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 9.0 GO:0005730 nucleolus(GO:0005730)
3.0 8.9 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.8 8.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 8.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 8.2 GO:0000790 nuclear chromatin(GO:0000790)
2.6 7.9 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 7.7 GO:0031985 Golgi cisterna(GO:0031985)
0.1 7.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 7.1 GO:0005884 actin filament(GO:0005884)
0.0 6.8 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 98 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 22.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.0 17.6 GO:0017166 vinculin binding(GO:0017166)
5.5 16.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.3 14.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 12.9 GO:0030165 PDZ domain binding(GO:0030165)
0.2 12.7 GO:0005254 chloride channel activity(GO:0005254)
0.3 11.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.7 11.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.2 11.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 10.6 GO:0005525 GTP binding(GO:0005525)
2.4 9.4 GO:0046923 ER retention sequence binding(GO:0046923)
1.4 8.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.0 7.9 GO:0035877 death effector domain binding(GO:0035877)
1.7 6.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.6 6.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 6.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.5 5.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 5.9 GO:0005522 profilin binding(GO:0005522)
1.0 5.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 5.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)