Motif ID: Emx1_Emx2

Z-value: 0.534

Transcription factors associated with Emx1_Emx2:

Gene SymbolEntrez IDGene Name
Emx1 ENSMUSG00000033726.8 Emx1
Emx2 ENSMUSG00000043969.4 Emx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Emx1mm10_v2_chr6_+_85187438_851875100.541.7e-06Click!
Emx2mm10_v2_chr19_+_59458372_59458450-0.181.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Emx1_Emx2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 173 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_82505749 7.340 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr4_-_82505274 6.788 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr4_-_82505707 6.090 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr4_+_118961578 3.668 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr1_-_158356258 3.484 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr17_-_36032682 2.802 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr11_-_42000284 2.371 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr10_+_90071095 2.360 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_20728219 2.309 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr16_-_63864114 2.242 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr10_+_81257277 2.167 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
Matk


megakaryocyte-associated tyrosine kinase


chr16_-_97170707 2.128 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr3_+_127633134 2.047 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr2_-_156392829 1.966 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr7_-_103827922 1.862 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr16_+_11406618 1.696 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr1_+_32172711 1.580 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr7_+_126781483 1.540 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr2_-_157566319 1.475 ENSMUST00000109528.2
ENSMUST00000088494.2
Blcap

bladder cancer associated protein homolog (human)

chr8_-_21906412 1.430 ENSMUST00000051965.4
Defb11
defensin beta 11

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.1 20.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 3.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 3.5 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.9 2.8 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.3 2.4 GO:0071420 cellular response to histamine(GO:0071420)
0.2 2.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 2.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.7 2.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 2.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.7 2.1 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 2.0 GO:0048469 cell maturation(GO:0048469)
0.4 1.5 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 1.4 GO:0042742 defense response to bacterium(GO:0042742)
0.3 1.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 1.3 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.4 1.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.3 1.0 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 20.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 2.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 2.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.3 GO:0030426 growth cone(GO:0030426)
0.5 1.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.4 1.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 0.9 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 0.6 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 20.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.2 3.7 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.4 2.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 2.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 2.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.5 1.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.1 1.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 0.8 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.1 0.8 GO:0051400 BH domain binding(GO:0051400)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)