Motif ID: Emx1_Emx2

Z-value: 0.534

Transcription factors associated with Emx1_Emx2:

Gene SymbolEntrez IDGene Name
Emx1 ENSMUSG00000033726.8 Emx1
Emx2 ENSMUSG00000043969.4 Emx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Emx1mm10_v2_chr6_+_85187438_851875100.541.7e-06Click!
Emx2mm10_v2_chr19_+_59458372_59458450-0.181.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Emx1_Emx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_82505749 7.340 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr4_-_82505274 6.788 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr4_-_82505707 6.090 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr4_+_118961578 3.668 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr1_-_158356258 3.484 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr17_-_36032682 2.802 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr11_-_42000284 2.371 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr10_+_90071095 2.360 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_20728219 2.309 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr16_-_63864114 2.242 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr10_+_81257277 2.167 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
Matk


megakaryocyte-associated tyrosine kinase


chr16_-_97170707 2.128 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr3_+_127633134 2.047 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr2_-_156392829 1.966 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr7_-_103827922 1.862 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr16_+_11406618 1.696 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr1_+_32172711 1.580 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr7_+_126781483 1.540 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr2_-_157566319 1.475 ENSMUST00000109528.2
ENSMUST00000088494.2
Blcap

bladder cancer associated protein homolog (human)

chr8_-_21906412 1.430 ENSMUST00000051965.4
Defb11
defensin beta 11
chr2_-_160619971 1.422 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr5_-_118244861 1.365 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr8_-_125898291 1.208 ENSMUST00000047239.6
Pcnxl2
pecanex-like 2 (Drosophila)
chr15_+_99006056 1.134 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr6_-_57535422 1.114 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr17_-_32822200 1.105 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr8_+_69300776 1.087 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr10_+_69787431 1.076 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr15_-_33687840 1.014 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr12_-_90969768 0.971 ENSMUST00000181184.1
4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr10_+_81183000 0.955 ENSMUST00000178422.1
Dapk3
death-associated protein kinase 3
chr13_+_16014457 0.879 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr4_+_126609818 0.861 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr10_+_79996479 0.839 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr9_-_15301555 0.821 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr8_+_45507768 0.801 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr1_+_93685574 0.783 ENSMUST00000027499.6
Bok
BCL2-related ovarian killer protein
chr7_+_43672003 0.746 ENSMUST00000038332.8
Ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr15_-_102510681 0.733 ENSMUST00000171565.1
Map3k12
mitogen-activated protein kinase kinase kinase 12
chr10_-_49783259 0.718 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr4_+_110397661 0.712 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr14_+_55560010 0.710 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr12_-_98577940 0.699 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr16_-_26371828 0.695 ENSMUST00000023154.2
Cldn1
claudin 1
chr3_+_146852359 0.680 ENSMUST00000038090.5
ENSMUST00000170055.1
Ttll7

tubulin tyrosine ligase-like family, member 7

chr8_+_72219726 0.673 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr3_+_32436376 0.656 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_-_40085823 0.656 ENSMUST00000181756.1
Gm16894
predicted gene, 16894
chr9_+_34904913 0.650 ENSMUST00000045091.6
Kirrel3
kin of IRRE like 3 (Drosophila)
chr11_+_121237216 0.649 ENSMUST00000103015.3
Narf
nuclear prelamin A recognition factor
chr12_-_84617326 0.648 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr7_-_97738222 0.644 ENSMUST00000084986.6
Aqp11
aquaporin 11
chr1_+_163779575 0.644 ENSMUST00000027877.6
ENSMUST00000077642.5
Kifap3

kinesin-associated protein 3

chr6_+_129533183 0.622 ENSMUST00000032264.6
Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr6_+_79818031 0.621 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chr13_-_97747399 0.619 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr13_-_23934156 0.618 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr4_+_110397764 0.613 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr9_+_56418624 0.584 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chr7_-_30534180 0.584 ENSMUST00000044338.4
Arhgap33
Rho GTPase activating protein 33
chr6_-_144209448 0.583 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr6_-_129533267 0.575 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr1_-_144177259 0.560 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr5_+_135009152 0.551 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chr6_-_144209558 0.544 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr15_+_99295087 0.529 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr10_+_102158858 0.520 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr18_-_6241486 0.517 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr8_+_34054622 0.506 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr6_-_144209471 0.504 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chrX_+_8271133 0.494 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr1_-_184999549 0.490 ENSMUST00000027929.4
Mark1
MAP/microtubule affinity-regulating kinase 1
chr7_+_39588931 0.490 ENSMUST00000178791.1
ENSMUST00000098511.3
Gm2058

predicted gene 2058

chr17_-_47043039 0.480 ENSMUST00000075152.5
Gm4945
predicted gene 4945
chr3_+_32436151 0.478 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr14_+_58893465 0.460 ENSMUST00000079960.1
Rpl13-ps3
ribosomal protein L13, pseudogene 3
chr2_+_175469985 0.456 ENSMUST00000109042.3
ENSMUST00000109002.2
ENSMUST00000109043.2
ENSMUST00000143490.1
Gm8923



predicted gene 8923



chr7_-_5413145 0.453 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr8_+_93810832 0.445 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr18_-_73754457 0.444 ENSMUST00000041138.2
Elac1
elaC homolog 1 (E. coli)
chr14_-_57133585 0.441 ENSMUST00000039380.8
Gjb6
gap junction protein, beta 6
chr2_+_175372436 0.437 ENSMUST00000131676.1
ENSMUST00000109048.2
ENSMUST00000109047.2
Gm4723


predicted gene 4723


chr13_-_97747373 0.436 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr7_+_129591859 0.434 ENSMUST00000084519.5
Wdr11
WD repeat domain 11
chr17_-_45599603 0.420 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr4_+_32657107 0.399 ENSMUST00000071642.4
ENSMUST00000178134.1
Mdn1

midasin homolog (yeast)

chr4_-_64276595 0.399 ENSMUST00000141162.1
Gm11217
predicted gene 11217
chr4_+_83417715 0.390 ENSMUST00000030206.3
ENSMUST00000071544.4
Snapc3

small nuclear RNA activating complex, polypeptide 3

chr3_-_151749877 0.384 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr3_-_37125943 0.384 ENSMUST00000029275.5
Il2
interleukin 2
chr2_-_175703646 0.381 ENSMUST00000109027.2
ENSMUST00000179061.1
ENSMUST00000131041.1
Gm4245


predicted gene 4245


chrX_-_150814265 0.373 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr17_+_29274078 0.370 ENSMUST00000149405.2
BC004004
cDNA sequence BC004004
chr8_-_85432841 0.366 ENSMUST00000047749.5
4921524J17Rik
RIKEN cDNA 4921524J17 gene
chr8_-_8690493 0.363 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chr2_-_34826071 0.362 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr17_-_45686899 0.358 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr9_+_72958785 0.358 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr17_+_46772635 0.357 ENSMUST00000071430.5
2310039H08Rik
RIKEN cDNA 2310039H08 gene
chr2_+_144594054 0.356 ENSMUST00000136628.1
Gm561
predicted gene 561
chr2_-_37647199 0.352 ENSMUST00000028279.3
Strbp
spermatid perinuclear RNA binding protein
chr12_-_12940600 0.349 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr17_+_45734506 0.347 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr4_-_155645408 0.346 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chr8_+_85432686 0.342 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr5_-_139345149 0.342 ENSMUST00000049630.6
Cox19
cytochrome c oxidase assembly protein 19
chr16_-_59553970 0.336 ENSMUST00000139989.1
Crybg3
beta-gamma crystallin domain containing 3
chrX_+_106027300 0.335 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr5_-_121502980 0.328 ENSMUST00000079368.3
Adam1b
a disintegrin and metallopeptidase domain 1b
chr11_+_72689997 0.319 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr15_+_80711292 0.314 ENSMUST00000067689.7
Tnrc6b
trinucleotide repeat containing 6b
chr12_-_87388317 0.309 ENSMUST00000021424.4
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
chr17_+_14943184 0.299 ENSMUST00000052691.8
ENSMUST00000164837.2
ENSMUST00000174004.1
1600012H06Rik


RIKEN cDNA 1600012H06 gene


chrX_+_106027259 0.298 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr2_-_34826187 0.292 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2


F-box and WD-40 domain protein 2


chr3_-_130730375 0.285 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr2_-_5676046 0.284 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr16_+_21794320 0.276 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chrX_-_160994665 0.274 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr4_-_150914401 0.270 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr18_-_6241470 0.266 ENSMUST00000163210.1
Kif5b
kinesin family member 5B
chr9_-_124304718 0.259 ENSMUST00000071300.6
2010315B03Rik
RIKEN cDNA 2010315B03 gene
chr9_+_108648720 0.254 ENSMUST00000098384.2
Gm10621
predicted gene 10621
chr12_+_36314160 0.247 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr3_+_121531603 0.230 ENSMUST00000180804.1
A530020G20Rik
RIKEN cDNA A530020G20 gene
chr4_+_41966058 0.228 ENSMUST00000108026.2
Gm20938
predicted gene, 20938
chr2_+_36230426 0.228 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr6_+_124304646 0.221 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr9_-_53667429 0.217 ENSMUST00000166367.1
ENSMUST00000034529.7
Cul5

cullin 5

chrX_-_74393003 0.214 ENSMUST00000015427.6
Fam3a
family with sequence similarity 3, member A
chr3_-_146495115 0.211 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr1_-_23909687 0.210 ENSMUST00000129254.1
Smap1
small ArfGAP 1
chrX_-_102505359 0.194 ENSMUST00000087916.4
Hdac8
histone deacetylase 8
chr6_+_17749170 0.194 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chrM_+_2743 0.192 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr14_+_53324632 0.190 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr13_-_99516537 0.189 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr7_+_126976338 0.181 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr1_-_37496095 0.178 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr2_-_12419456 0.177 ENSMUST00000154899.1
ENSMUST00000028105.6
Fam188a

family with sequence similarity 188, member A

chr2_+_69789647 0.176 ENSMUST00000112266.1
Phospho2
phosphatase, orphan 2
chr15_-_36496722 0.163 ENSMUST00000057486.7
Ankrd46
ankyrin repeat domain 46
chr5_-_28210022 0.161 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr3_-_49757257 0.157 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chrX_-_134111852 0.151 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr10_-_25297055 0.149 ENSMUST00000177124.1
Akap7
A kinase (PRKA) anchor protein 7
chr10_-_76110956 0.143 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr2_-_12419387 0.141 ENSMUST00000124515.1
Fam188a
family with sequence similarity 188, member A
chr7_-_84679346 0.136 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr10_+_128322443 0.136 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr6_+_37870786 0.129 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr4_-_134245579 0.110 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr4_+_102589687 0.102 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr13_+_94976435 0.097 ENSMUST00000160409.1
ENSMUST00000159647.1
ENSMUST00000167155.1
Wdr41


WD repeat domain 41


chr7_-_142661858 0.090 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr8_+_31089471 0.084 ENSMUST00000036631.7
ENSMUST00000170204.1
Dusp26

dual specificity phosphatase 26 (putative)

chr14_-_18893376 0.077 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr7_-_42706369 0.071 ENSMUST00000180131.1
Gm17067
predicted gene 17067
chr3_+_88716838 0.067 ENSMUST00000029692.8
ENSMUST00000171645.1
Rit1

Ras-like without CAAX 1

chr1_-_97761538 0.066 ENSMUST00000171129.1
Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr2_-_155930190 0.058 ENSMUST00000109636.4
ENSMUST00000109631.1
Uqcc1

ubiquinol-cytochrome c reductase complex assembly factor 1

chr5_+_121749196 0.051 ENSMUST00000161064.1
Atxn2
ataxin 2
chr15_+_16778101 0.051 ENSMUST00000026432.6
Cdh9
cadherin 9
chr11_+_17257558 0.046 ENSMUST00000000594.2
ENSMUST00000156784.1
C1d

C1D nuclear receptor co-repressor

chr6_-_89595647 0.039 ENSMUST00000032172.8
ENSMUST00000113550.3
Chchd6

coiled-coil-helix-coiled-coil-helix domain containing 6

chrM_+_11734 0.037 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr12_+_80463095 0.028 ENSMUST00000038185.8
Exd2
exonuclease 3'-5' domain containing 2
chr13_+_23763660 0.024 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr4_-_94603239 0.022 ENSMUST00000107107.2
Plaa
phospholipase A2, activating protein
chr2_-_73580288 0.020 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr4_-_149099802 0.016 ENSMUST00000103217.4
Pex14
peroxisomal biogenesis factor 14
chr11_+_6560183 0.006 ENSMUST00000109722.2
Ccm2
cerebral cavernous malformation 2
chr11_+_5788480 0.004 ENSMUST00000109845.1
ENSMUST00000020769.7
ENSMUST00000102928.4
Dbnl


drebrin-like



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 20.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.9 2.8 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.7 2.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.7 2.1 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.4 1.5 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.4 1.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.3 1.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 0.7 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.3 1.0 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.3 2.4 GO:0071420 cellular response to histamine(GO:0071420)
0.2 2.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 0.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.6 GO:0051542 elastin biosynthetic process(GO:0051542)
0.2 0.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 2.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 0.8 GO:0035617 stress granule disassembly(GO:0035617)
0.2 0.9 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.7 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 0.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.3 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation(GO:0018307) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) glyoxal catabolic process(GO:1903190) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) positive regulation of androgen receptor activity(GO:2000825)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 1.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.2 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 3.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.8 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.2 GO:0071455 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.1 3.5 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 1.3 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.4 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 2.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 2.0 GO:0048469 cell maturation(GO:0048469)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.4 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.4 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.2 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 0.2 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 20.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 1.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3 0.9 GO:0043512 inhibin A complex(GO:0043512)
0.2 2.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.6 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.1 2.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 2.3 GO:0030426 growth cone(GO:0030426)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.6 20.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 1.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.4 2.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 2.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 0.8 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
0.2 0.6 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 2.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.7 GO:0052630 CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.1 0.3 GO:0044388 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) small protein activating enzyme binding(GO:0044388) cupric ion binding(GO:1903135) cuprous ion binding(GO:1903136) glyoxalase (glycolic acid-forming) activity(GO:1990422)
0.1 1.6 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.1 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.8 GO:0051400 BH domain binding(GO:0051400)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.8 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 0.6 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.4 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)