Motif ID: Ep300

Z-value: 0.559


Transcription factors associated with Ep300:

Gene SymbolEntrez IDGene Name
Ep300 ENSMUSG00000055024.6 Ep300

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ep300mm10_v2_chr15_+_81586206_81586250-0.103.9e-01Click!


Activity profile for motif Ep300.

activity profile for motif Ep300


Sorted Z-values histogram for motif Ep300

Sorted Z-values for motif Ep300



Network of associatons between targets according to the STRING database.



First level regulatory network of Ep300

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_98348404 5.579 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr9_-_29411736 4.165 ENSMUST00000115236.1
Ntm
neurotrimin
chr6_+_99692679 3.380 ENSMUST00000101122.1
Gpr27
G protein-coupled receptor 27
chr19_+_23758819 3.340 ENSMUST00000025830.7
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr8_-_84800344 3.189 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr1_-_21961581 3.026 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr11_+_97415527 2.820 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr6_-_136173492 2.530 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr1_-_21961942 2.520 ENSMUST00000115300.1
Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr18_+_51117754 2.428 ENSMUST00000116639.2
Prr16
proline rich 16
chr17_+_55445550 2.373 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr5_+_130448801 2.351 ENSMUST00000111288.2
Caln1
calneuron 1
chr9_-_29412204 2.250 ENSMUST00000115237.1
Ntm
neurotrimin
chr7_+_96522342 2.209 ENSMUST00000129737.1
Tenm4
teneurin transmembrane protein 4
chr1_-_83408190 2.188 ENSMUST00000160953.1
Sphkap
SPHK1 interactor, AKAP domain containing
chr4_+_125490688 2.076 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr6_+_65671590 1.954 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr10_+_58813359 1.905 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr1_-_87573825 1.885 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr16_-_52452465 1.823 ENSMUST00000170035.1
ENSMUST00000164728.1
Alcam

activated leukocyte cell adhesion molecule


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.8 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 6.3 GO:0071805 potassium ion transmembrane transport(GO:0071805)
1.9 5.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 4.7 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
1.1 3.4 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.2 3.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 3.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.4 2.9 GO:0005513 detection of calcium ion(GO:0005513)
0.3 2.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 2.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 2.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 2.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.6 2.2 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 2.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 2.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 2.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3 2.0 GO:0061042 vascular wound healing(GO:0061042)
0.2 1.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4 1.8 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 1.8 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 6.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.4 GO:0008021 synaptic vesicle(GO:0008021)
0.2 3.1 GO:0042101 T cell receptor complex(GO:0042101)
0.2 2.5 GO:0043083 synaptic cleft(GO:0043083)
0.1 2.5 GO:0097440 apical dendrite(GO:0097440)
0.2 2.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 2.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.8 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.8 GO:0030018 Z disc(GO:0030018)
0.0 1.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 1.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.5 1.4 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.0 1.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.4 GO:0030139 endocytic vesicle(GO:0030139)
0.2 1.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 5.6 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.2 5.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 3.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 3.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 3.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 2.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 2.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.5 2.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 2.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 2.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 2.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.4 2.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 2.0 GO:0008201 heparin binding(GO:0008201)
0.0 1.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.7 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)