Motif ID: Epas1_Bcl3
Z-value: 1.872
Transcription factors associated with Epas1_Bcl3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Bcl3 | ENSMUSG00000053175.10 | Bcl3 |
Epas1 | ENSMUSG00000024140.9 | Epas1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Epas1 | mm10_v2_chr17_+_86753900_86753914 | 0.32 | 6.7e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
7.4 | 22.3 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
5.8 | 40.3 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
4.7 | 18.9 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
4.6 | 27.7 | GO:0046880 | regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) |
4.3 | 13.0 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
3.3 | 13.2 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
3.2 | 19.3 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
3.2 | 9.5 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
2.7 | 8.0 | GO:0098528 | terpenoid catabolic process(GO:0016115) skeletal muscle fiber differentiation(GO:0098528) |
2.6 | 20.5 | GO:0097264 | self proteolysis(GO:0097264) |
2.5 | 15.2 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
2.2 | 15.5 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699) |
2.0 | 6.0 | GO:1901731 | calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731) |
1.7 | 8.7 | GO:0007256 | activation of JNKK activity(GO:0007256) |
1.7 | 18.9 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
1.7 | 5.0 | GO:0010958 | regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963) |
1.7 | 25.1 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
1.7 | 8.3 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
1.6 | 8.2 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) regulation of axon diameter(GO:0031133) interneuron migration(GO:1904936) |
1.6 | 3.2 | GO:0001803 | type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
1.6 | 9.4 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
1.5 | 13.9 | GO:0098907 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
1.5 | 7.6 | GO:0034436 | glycoprotein transport(GO:0034436) |
1.5 | 7.6 | GO:0001778 | plasma membrane repair(GO:0001778) |
1.5 | 26.8 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
1.4 | 6.9 | GO:0075136 | response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136) |
1.3 | 5.3 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
1.2 | 5.9 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
1.2 | 3.5 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
1.1 | 11.2 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
1.1 | 3.2 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
1.1 | 3.2 | GO:1900736 | regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) |
1.0 | 3.1 | GO:1901228 | regulation of osteoclast proliferation(GO:0090289) negative regulation of bone mineralization involved in bone maturation(GO:1900158) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
1.0 | 7.2 | GO:0061042 | vascular wound healing(GO:0061042) |
1.0 | 3.1 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
1.0 | 8.1 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
1.0 | 21.3 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
1.0 | 4.0 | GO:0097167 | circadian regulation of translation(GO:0097167) |
1.0 | 5.0 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
0.9 | 5.6 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
0.9 | 2.7 | GO:0003289 | atrial septum primum morphogenesis(GO:0003289) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
0.9 | 6.2 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.9 | 6.0 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.8 | 4.9 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
0.8 | 2.3 | GO:0031086 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
0.7 | 2.2 | GO:0030070 | insulin processing(GO:0030070) |
0.7 | 7.3 | GO:0071435 | potassium ion export(GO:0071435) |
0.7 | 3.6 | GO:0032423 | regulation of mismatch repair(GO:0032423) |
0.7 | 19.2 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.7 | 13.5 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
0.7 | 16.2 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
0.7 | 4.7 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.6 | 1.9 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
0.6 | 12.9 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.6 | 1.9 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
0.6 | 2.4 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
0.6 | 1.7 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.6 | 1.7 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
0.6 | 8.3 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.5 | 4.3 | GO:0035584 | calcium-mediated signaling using intracellular calcium source(GO:0035584) |
0.5 | 11.4 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.5 | 3.3 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
0.5 | 3.8 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
0.5 | 6.9 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.5 | 1.1 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
0.5 | 1.6 | GO:0002513 | tolerance induction to self antigen(GO:0002513) |
0.5 | 13.7 | GO:1901381 | positive regulation of potassium ion transmembrane transport(GO:1901381) |
0.5 | 6.5 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
0.5 | 6.0 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
0.5 | 1.9 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
0.5 | 10.7 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.5 | 5.6 | GO:0015732 | prostaglandin transport(GO:0015732) |
0.4 | 4.5 | GO:0007379 | segment specification(GO:0007379) |
0.4 | 8.1 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
0.4 | 5.0 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.4 | 2.4 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
0.4 | 2.8 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
0.4 | 3.4 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.4 | 3.6 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
0.4 | 1.4 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
0.3 | 11.6 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
0.3 | 6.2 | GO:0010107 | potassium ion import(GO:0010107) |
0.3 | 1.6 | GO:0021856 | cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375) |
0.3 | 0.6 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.3 | 13.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.3 | 9.9 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
0.3 | 2.1 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
0.3 | 28.2 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
0.3 | 1.4 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
0.3 | 19.4 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.3 | 0.8 | GO:0036015 | response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
0.3 | 6.5 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
0.3 | 8.8 | GO:0034605 | cellular response to heat(GO:0034605) |
0.2 | 4.4 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
0.2 | 6.0 | GO:0072348 | sulfur compound transport(GO:0072348) |
0.2 | 1.8 | GO:0006265 | DNA topological change(GO:0006265) |
0.2 | 5.1 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
0.2 | 1.3 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263) |
0.2 | 0.9 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
0.2 | 2.8 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.2 | 1.0 | GO:0045605 | negative regulation of epidermal cell differentiation(GO:0045605) |
0.2 | 5.2 | GO:0060074 | synapse maturation(GO:0060074) |
0.2 | 0.8 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.2 | 0.7 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
0.2 | 7.0 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.2 | 4.7 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
0.2 | 1.0 | GO:0051341 | regulation of oxidoreductase activity(GO:0051341) |
0.2 | 11.5 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.2 | 6.8 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.2 | 0.6 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
0.2 | 1.6 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
0.2 | 3.8 | GO:0034340 | response to type I interferon(GO:0034340) |
0.1 | 2.1 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
0.1 | 1.3 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 2.7 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.1 | 5.7 | GO:0007623 | circadian rhythm(GO:0007623) |
0.1 | 15.1 | GO:0006165 | nucleoside diphosphate phosphorylation(GO:0006165) |
0.1 | 2.0 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
0.1 | 4.6 | GO:0097178 | ruffle assembly(GO:0097178) |
0.1 | 1.0 | GO:0036506 | maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.1 | 1.0 | GO:0031053 | primary miRNA processing(GO:0031053) |
0.1 | 3.0 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
0.1 | 0.8 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.1 | 3.4 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
0.1 | 1.6 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.1 | 0.5 | GO:0019236 | response to pheromone(GO:0019236) |
0.1 | 2.9 | GO:0010955 | negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318) |
0.1 | 0.5 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.1 | 2.5 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
0.1 | 7.5 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
0.1 | 16.8 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
0.1 | 1.8 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.1 | 5.8 | GO:0051298 | centrosome duplication(GO:0051298) |
0.1 | 0.6 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
0.1 | 2.0 | GO:0019228 | neuronal action potential(GO:0019228) |
0.1 | 1.0 | GO:0030953 | astral microtubule organization(GO:0030953) |
0.1 | 1.5 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.1 | 0.2 | GO:1902950 | regulation of dendritic spine maintenance(GO:1902950) positive regulation of dendritic spine maintenance(GO:1902952) |
0.1 | 2.3 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.1 | 4.1 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
0.1 | 3.5 | GO:0022900 | electron transport chain(GO:0022900) |
0.1 | 1.9 | GO:0008542 | visual learning(GO:0008542) |
0.1 | 5.8 | GO:0098792 | xenophagy(GO:0098792) |
0.1 | 6.3 | GO:0051291 | protein heterooligomerization(GO:0051291) |
0.0 | 0.7 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
0.0 | 1.5 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 3.2 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
0.0 | 2.4 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
0.0 | 0.2 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.0 | 0.3 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.0 | 0.2 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
0.0 | 2.2 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.0 | 2.7 | GO:0048515 | spermatid differentiation(GO:0048515) |
0.0 | 0.3 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.0 | 0.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.0 | 3.4 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
0.0 | 0.2 | GO:0043046 | DNA methylation involved in gamete generation(GO:0043046) |
0.0 | 0.7 | GO:0006754 | ATP biosynthetic process(GO:0006754) |
0.0 | 0.0 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
0.0 | 0.3 | GO:0032402 | melanosome transport(GO:0032402) |
0.0 | 0.1 | GO:0032264 | IMP salvage(GO:0032264) |
0.0 | 0.3 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 0.4 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
0.0 | 0.1 | GO:0021684 | cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.0 | 6.2 | GO:0030036 | actin cytoskeleton organization(GO:0030036) |
0.0 | 3.5 | GO:0006397 | mRNA processing(GO:0006397) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
9.2 | 27.7 | GO:0043512 | inhibin A complex(GO:0043512) |
4.3 | 21.7 | GO:0030314 | junctional membrane complex(GO:0030314) |
3.0 | 11.9 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
2.8 | 19.4 | GO:0038037 | G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) |
2.5 | 15.2 | GO:0008091 | spectrin(GO:0008091) |
2.2 | 44.7 | GO:0032279 | asymmetric synapse(GO:0032279) |
1.9 | 9.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
1.5 | 9.3 | GO:0032009 | early phagosome(GO:0032009) |
1.5 | 6.0 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
1.5 | 7.4 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
1.3 | 6.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
1.3 | 11.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
1.0 | 5.1 | GO:0044316 | cone cell pedicle(GO:0044316) |
1.0 | 15.5 | GO:0031143 | pseudopodium(GO:0031143) |
0.8 | 6.9 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.7 | 2.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.7 | 13.9 | GO:0031430 | M band(GO:0031430) |
0.6 | 8.4 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.6 | 2.8 | GO:0042583 | chromaffin granule(GO:0042583) |
0.5 | 1.1 | GO:0031523 | Myb complex(GO:0031523) |
0.5 | 7.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.5 | 6.3 | GO:0097449 | astrocyte projection(GO:0097449) |
0.5 | 14.2 | GO:0033268 | node of Ranvier(GO:0033268) |
0.4 | 6.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.4 | 14.2 | GO:0097440 | apical dendrite(GO:0097440) |
0.4 | 1.8 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.3 | 11.2 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.3 | 1.0 | GO:1903095 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
0.3 | 5.6 | GO:0032433 | filopodium tip(GO:0032433) |
0.3 | 22.6 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.3 | 8.3 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.3 | 62.4 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.2 | 12.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.2 | 6.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.2 | 32.7 | GO:0043197 | dendritic spine(GO:0043197) |
0.2 | 0.6 | GO:0071953 | elastic fiber(GO:0071953) |
0.2 | 1.5 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.2 | 0.7 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
0.2 | 31.4 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.2 | 3.4 | GO:0071564 | npBAF complex(GO:0071564) |
0.2 | 10.1 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
0.2 | 2.2 | GO:0031932 | TORC2 complex(GO:0031932) |
0.2 | 18.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.1 | 1.0 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.1 | 8.7 | GO:0055037 | recycling endosome(GO:0055037) |
0.1 | 3.6 | GO:0097060 | synaptic membrane(GO:0097060) |
0.1 | 7.3 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.1 | 3.5 | GO:0030315 | T-tubule(GO:0030315) |
0.1 | 7.1 | GO:0043204 | perikaryon(GO:0043204) |
0.1 | 3.3 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.1 | 14.7 | GO:0000139 | Golgi membrane(GO:0000139) |
0.1 | 10.6 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.1 | 7.6 | GO:0030016 | myofibril(GO:0030016) |
0.1 | 0.2 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.1 | 4.7 | GO:0072562 | blood microparticle(GO:0072562) |
0.1 | 6.9 | GO:0043679 | axon terminus(GO:0043679) |
0.1 | 1.7 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.1 | 5.0 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.1 | 0.7 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.1 | 15.8 | GO:0043025 | neuronal cell body(GO:0043025) |
0.1 | 3.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.1 | 2.1 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 1.5 | GO:0034451 | centriolar satellite(GO:0034451) |
0.1 | 35.9 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.0 | 0.4 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.0 | 3.2 | GO:0036477 | somatodendritic compartment(GO:0036477) |
0.0 | 1.7 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 0.9 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 10.3 | GO:0045202 | synapse(GO:0045202) |
0.0 | 1.9 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 2.0 | GO:0009986 | cell surface(GO:0009986) |
0.0 | 1.9 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 1.0 | GO:0005924 | cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055) |
0.0 | 0.9 | GO:0005844 | polysome(GO:0005844) |
0.0 | 2.1 | GO:0016605 | PML body(GO:0016605) |
0.0 | 2.9 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 5.1 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.0 | 0.8 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.3 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 47.1 | GO:0016021 | integral component of membrane(GO:0016021) |
0.0 | 0.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 2.9 | GO:0005929 | cilium(GO:0005929) |
0.0 | 6.0 | GO:0005813 | centrosome(GO:0005813) |
0.0 | 2.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
7.2 | 21.7 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763) |
5.2 | 15.5 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
4.7 | 18.9 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
4.1 | 24.8 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
3.2 | 19.3 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
3.2 | 9.5 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
3.1 | 27.7 | GO:0034711 | inhibin binding(GO:0034711) |
2.6 | 13.2 | GO:0055100 | adiponectin binding(GO:0055100) |
2.5 | 7.6 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437) |
2.2 | 13.5 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
2.1 | 12.9 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
2.0 | 11.7 | GO:0032051 | clathrin light chain binding(GO:0032051) |
1.9 | 40.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
1.6 | 6.5 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) |
1.6 | 6.3 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988) |
1.5 | 7.6 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
1.5 | 8.8 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
1.5 | 7.3 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
1.4 | 11.5 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
1.4 | 4.2 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
1.2 | 6.2 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
1.2 | 3.5 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
1.2 | 3.5 | GO:0004568 | chitinase activity(GO:0004568) |
1.1 | 18.2 | GO:0001223 | transcription coactivator binding(GO:0001223) |
1.1 | 3.2 | GO:0019770 | IgG receptor activity(GO:0019770) |
1.0 | 9.4 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
1.0 | 5.1 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
1.0 | 4.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.9 | 8.0 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.8 | 5.0 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.8 | 8.5 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.8 | 4.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.8 | 6.9 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.7 | 6.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.7 | 19.0 | GO:0005272 | sodium channel activity(GO:0005272) |
0.7 | 5.1 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
0.7 | 6.5 | GO:0034046 | poly(G) binding(GO:0034046) |
0.7 | 13.2 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.7 | 23.8 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.6 | 1.9 | GO:0019863 | IgE binding(GO:0019863) |
0.6 | 19.0 | GO:0030552 | cAMP binding(GO:0030552) |
0.6 | 35.0 | GO:0030507 | spectrin binding(GO:0030507) |
0.6 | 7.4 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.6 | 2.4 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
0.6 | 6.0 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.6 | 32.0 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.6 | 11.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.5 | 2.1 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
0.5 | 6.9 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.5 | 2.4 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.5 | 6.3 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.5 | 3.8 | GO:0048495 | Roundabout binding(GO:0048495) |
0.5 | 21.9 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.4 | 3.4 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.4 | 18.4 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.4 | 3.3 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.4 | 8.3 | GO:0031489 | myosin V binding(GO:0031489) |
0.4 | 8.3 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.3 | 1.7 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
0.3 | 3.1 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
0.3 | 5.3 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.3 | 5.0 | GO:0031005 | filamin binding(GO:0031005) |
0.3 | 1.8 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.3 | 9.3 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
0.2 | 2.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.2 | 1.0 | GO:0070878 | primary miRNA binding(GO:0070878) |
0.2 | 3.6 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
0.2 | 5.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.2 | 0.6 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.2 | 1.5 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.2 | 8.7 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.2 | 1.3 | GO:0036122 | BMP binding(GO:0036122) |
0.2 | 2.7 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
0.2 | 5.9 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.2 | 1.9 | GO:0070411 | I-SMAD binding(GO:0070411) |
0.1 | 0.7 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) |
0.1 | 2.6 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 1.6 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
0.1 | 14.2 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.1 | 1.4 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
0.1 | 7.3 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.1 | 0.2 | GO:0036004 | GAF domain binding(GO:0036004) |
0.1 | 1.3 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
0.1 | 1.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.1 | 2.9 | GO:0005112 | Notch binding(GO:0005112) |
0.1 | 0.4 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
0.1 | 3.1 | GO:0045182 | translation regulator activity(GO:0045182) |
0.1 | 1.5 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.1 | 7.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.1 | 1.9 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.1 | 0.8 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.1 | 7.0 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.1 | 2.3 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
0.1 | 1.9 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 1.0 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
0.1 | 0.3 | GO:0048185 | activin binding(GO:0048185) |
0.1 | 4.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 3.1 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.1 | 0.9 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
0.1 | 0.3 | GO:0031685 | adenosine receptor binding(GO:0031685) |
0.1 | 8.7 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
0.1 | 0.8 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 0.5 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
0.1 | 2.5 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 2.7 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 5.0 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
0.0 | 0.6 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.0 | 0.7 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 0.2 | GO:0045545 | syndecan binding(GO:0045545) |
0.0 | 5.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 1.7 | GO:0035250 | UDP-galactosyltransferase activity(GO:0035250) |
0.0 | 0.5 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.0 | 0.2 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 2.8 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 1.6 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
0.0 | 1.4 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.0 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.0 | 0.3 | GO:0034945 | dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595) |