Motif ID: Erg

Z-value: 1.526


Transcription factors associated with Erg:

Gene SymbolEntrez IDGene Name
Erg ENSMUSG00000040732.12 Erg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ergmm10_v2_chr16_-_95459245_954593840.458.9e-05Click!


Activity profile for motif Erg.

activity profile for motif Erg


Sorted Z-values histogram for motif Erg

Sorted Z-values for motif Erg



Network of associatons between targets according to the STRING database.



First level regulatory network of Erg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_38713235 24.355 ENSMUST00000023487.4
 Arhgap31
Rho GTPase activating protein 31
chr5_+_75152274 19.141 ENSMUST00000000476.8
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr12_+_75308308 18.582 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr9_-_54661870 17.718 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr2_+_30078584 17.640 ENSMUST00000045246.7
 Pkn3
protein kinase N3
chr14_-_25769033 15.675 ENSMUST00000069180.7
 Zcchc24
zinc finger, CCHC domain containing 24
chr9_-_54661666 14.741 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr11_-_101785252 14.124 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr10_-_78591945 13.875 ENSMUST00000040580.6
 Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr11_-_55419898 13.280 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr10_-_58675631 12.459 ENSMUST00000003312.4
 Edar
ectodysplasin-A receptor
chr2_-_101883010 12.196 ENSMUST00000154525.1
 Prr5l
proline rich 5 like
chr10_+_79988584 12.008 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr11_+_90030295 11.868 ENSMUST00000092788.3
 Tmem100
transmembrane protein 100
chr2_+_27677234 11.359 ENSMUST00000166775.1
 Rxra
retinoid X receptor alpha
chr12_-_56536895 11.243 ENSMUST00000001536.8
 Nkx2-1
NK2 homeobox 1
chr2_+_27677201 10.671 ENSMUST00000077257.5
 Rxra
retinoid X receptor alpha
chr2_-_101797650 10.617 ENSMUST00000141814.1
ENSMUST00000171088.1
ENSMUST00000043845.7
 Prr5l


proline rich 5 like


chr11_-_48816936 10.600 ENSMUST00000140800.1
 Trim41
tripartite motif-containing 41
chr2_-_156839790 10.486 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
 Gm14230


predicted gene 14230



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 219 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 32.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.8 30.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
7.6 22.8 GO:0038203 TORC2 signaling(GO:0038203)
4.4 22.0 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.7 20.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
6.4 19.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 18.9 GO:0010631 epithelial cell migration(GO:0010631)
2.5 14.9 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 14.8 GO:0014013 regulation of gliogenesis(GO:0014013)
1.7 13.9 GO:0016081 synaptic vesicle docking(GO:0016081)
0.4 13.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
1.9 13.3 GO:0007296 vitellogenesis(GO:0007296)
0.7 13.1 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.4 12.7 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
1.4 12.5 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.1 12.2 GO:0042572 retinol metabolic process(GO:0042572)
0.8 12.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
2.0 11.9 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
1.4 11.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
3.7 11.2 GO:0021759 globus pallidus development(GO:0021759)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 112 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 38.1 GO:0005730 nucleolus(GO:0005730)
0.2 34.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.7 33.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 31.0 GO:0030027 lamellipodium(GO:0030027)
0.3 23.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
1.6 22.8 GO:0031932 TORC2 complex(GO:0031932)
2.4 21.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 20.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 20.3 GO:0005902 microvillus(GO:0005902)
0.2 19.4 GO:0005884 actin filament(GO:0005884)
0.7 19.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
1.5 16.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.7 13.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 13.5 GO:0000922 spindle pole(GO:0000922)
3.3 13.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.7 13.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
2.4 12.0 GO:0032426 stereocilium tip(GO:0032426)
0.0 11.9 GO:0005667 transcription factor complex(GO:0005667)
0.4 10.5 GO:0005921 gap junction(GO:0005921)
0.1 10.5 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 145 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 33.0 GO:0051015 actin filament binding(GO:0051015)
3.0 32.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 32.1 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 29.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.3 22.1 GO:0017166 vinculin binding(GO:0017166)
3.7 22.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 21.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.8 18.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.3 18.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 17.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
1.0 16.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 16.4 GO:0008270 zinc ion binding(GO:0008270)
0.2 15.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.9 14.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.5 13.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 13.4 GO:0070888 E-box binding(GO:0070888)
4.4 13.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 12.4 GO:0050840 extracellular matrix binding(GO:0050840)
1.7 12.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 12.1 GO:0003779 actin binding(GO:0003779)