Motif ID: Esrrb_Esrra
Z-value: 1.056
Transcription factors associated with Esrrb_Esrra:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Esrra | ENSMUSG00000024955.7 | Esrra |
| Esrrb | ENSMUSG00000021255.11 | Esrrb |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Esrrb | mm10_v2_chr12_+_86421628_86421662 | 0.10 | 4.1e-01 | Click! |
| Esrra | mm10_v2_chr19_-_6921804_6921834 | 0.06 | 6.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 9.2 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
| 1.5 | 4.6 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 1.3 | 3.8 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) hematopoietic stem cell migration(GO:0035701) regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510) |
| 1.2 | 3.6 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 1.1 | 3.3 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 1.0 | 2.9 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 0.9 | 8.4 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.9 | 2.7 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 0.9 | 2.7 | GO:1901731 | calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731) |
| 0.8 | 2.4 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.7 | 8.6 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.7 | 4.0 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.6 | 1.9 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
| 0.6 | 1.9 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 0.6 | 8.5 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.6 | 2.4 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.6 | 2.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.6 | 3.5 | GO:0046549 | retinal cone cell development(GO:0046549) |
| 0.6 | 3.4 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.5 | 2.2 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
| 0.5 | 1.1 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
| 0.5 | 3.2 | GO:0046103 | inosine biosynthetic process(GO:0046103) |
| 0.5 | 2.1 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
| 0.5 | 4.7 | GO:0014832 | urinary bladder smooth muscle contraction(GO:0014832) |
| 0.5 | 5.5 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.5 | 1.9 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.5 | 1.4 | GO:0019043 | establishment of viral latency(GO:0019043) |
| 0.5 | 2.4 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
| 0.4 | 1.3 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
| 0.4 | 3.8 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.4 | 1.2 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) |
| 0.4 | 1.2 | GO:0060785 | regulation of apoptosis involved in tissue homeostasis(GO:0060785) |
| 0.4 | 1.1 | GO:0032513 | negative regulation of protein phosphatase type 2B activity(GO:0032513) |
| 0.4 | 9.9 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
| 0.4 | 1.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.4 | 2.5 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.3 | 1.0 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.3 | 1.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.3 | 1.0 | GO:0042822 | vitamin B6 metabolic process(GO:0042816) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) |
| 0.3 | 1.6 | GO:0019659 | glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
| 0.3 | 1.6 | GO:0090234 | cellular response to testosterone stimulus(GO:0071394) regulation of kinetochore assembly(GO:0090234) |
| 0.3 | 0.9 | GO:0071544 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544) |
| 0.3 | 2.2 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.3 | 0.3 | GO:2000823 | regulation of androgen receptor activity(GO:2000823) |
| 0.3 | 3.9 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.3 | 3.7 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.3 | 1.3 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
| 0.3 | 1.3 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.3 | 5.2 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.3 | 1.0 | GO:1990379 | lipid transport across blood brain barrier(GO:1990379) |
| 0.2 | 1.4 | GO:0021636 | trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) |
| 0.2 | 3.3 | GO:0030238 | male sex determination(GO:0030238) |
| 0.2 | 0.5 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
| 0.2 | 0.9 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.2 | 4.8 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.2 | 0.6 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.2 | 1.4 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.2 | 0.6 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.2 | 0.6 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 0.2 | 1.2 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
| 0.2 | 1.4 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.2 | 1.7 | GO:0002536 | respiratory burst involved in inflammatory response(GO:0002536) |
| 0.2 | 0.9 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.2 | 1.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.2 | 0.5 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
| 0.2 | 1.7 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.2 | 8.4 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.2 | 2.4 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.2 | 0.5 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.2 | 1.0 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.2 | 1.5 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.2 | 1.0 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.2 | 0.6 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
| 0.2 | 2.9 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.2 | 0.5 | GO:0002901 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 0.2 | 3.5 | GO:0001990 | regulation of systemic arterial blood pressure by hormone(GO:0001990) |
| 0.2 | 0.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.2 | 0.6 | GO:0021886 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 0.1 | 1.3 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.1 | 3.1 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 1.0 | GO:0051204 | protein insertion into mitochondrial membrane(GO:0051204) |
| 0.1 | 0.6 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.1 | 1.0 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 0.6 | GO:1902953 | positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) |
| 0.1 | 2.9 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 2.2 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.1 | 0.8 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
| 0.1 | 0.4 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.1 | 0.4 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.1 | 11.4 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
| 0.1 | 2.4 | GO:0007614 | short-term memory(GO:0007614) |
| 0.1 | 0.4 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
| 0.1 | 0.4 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.1 | 0.4 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
| 0.1 | 1.4 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 1.6 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.1 | 0.6 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.1 | 0.9 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.1 | 2.9 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.1 | 0.6 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 0.1 | 0.3 | GO:2000612 | regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of somatic stem cell population maintenance(GO:1904672) negative regulation of somatic stem cell population maintenance(GO:1904673) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612) |
| 0.1 | 4.1 | GO:0051966 | regulation of synaptic transmission, glutamatergic(GO:0051966) |
| 0.1 | 0.4 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.1 | 5.3 | GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068) |
| 0.1 | 0.7 | GO:0061000 | negative regulation of dendritic spine development(GO:0061000) |
| 0.1 | 2.4 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.1 | 5.7 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.1 | 0.3 | GO:2000813 | negative regulation of barbed-end actin filament capping(GO:2000813) |
| 0.1 | 0.3 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) UDP metabolic process(GO:0046048) dUDP metabolic process(GO:0046077) |
| 0.1 | 0.7 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.1 | 0.4 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
| 0.1 | 0.3 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 0.1 | 2.5 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.1 | 2.1 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 2.9 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.1 | 0.2 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
| 0.1 | 1.7 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 0.3 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.1 | 0.6 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.1 | 1.2 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 2.6 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.1 | 0.5 | GO:1900107 | regulation of nodal signaling pathway(GO:1900107) |
| 0.1 | 1.4 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 0.1 | 2.1 | GO:0031103 | axon regeneration(GO:0031103) |
| 0.1 | 1.6 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.1 | 1.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.1 | 3.8 | GO:0042073 | intraciliary transport(GO:0042073) |
| 0.1 | 0.2 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
| 0.1 | 0.5 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.1 | 1.5 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.1 | 5.0 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.1 | 3.8 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.1 | 0.3 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 0.1 | 1.2 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.1 | 0.3 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.1 | 1.1 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.1 | 0.2 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
| 0.1 | 0.8 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 0.2 | GO:0034214 | protein hexamerization(GO:0034214) |
| 0.1 | 0.5 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.1 | 0.6 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.1 | 1.7 | GO:0014066 | regulation of phosphatidylinositol 3-kinase signaling(GO:0014066) |
| 0.1 | 0.6 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.1 | 0.4 | GO:0046607 | positive regulation of centrosome cycle(GO:0046607) |
| 0.1 | 0.4 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.1 | 0.4 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
| 0.1 | 0.7 | GO:0010388 | cullin deneddylation(GO:0010388) |
| 0.1 | 0.5 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
| 0.1 | 0.6 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) long-chain fatty acid import(GO:0044539) |
| 0.1 | 0.2 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.0 | 0.4 | GO:0023021 | termination of signal transduction(GO:0023021) |
| 0.0 | 2.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 2.0 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.9 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.0 | 0.4 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.0 | 0.2 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.2 | GO:0072488 | nitrogen utilization(GO:0019740) ammonium transmembrane transport(GO:0072488) |
| 0.0 | 0.4 | GO:0032225 | regulation of synaptic transmission, dopaminergic(GO:0032225) |
| 0.0 | 0.5 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 1.2 | GO:0045471 | response to ethanol(GO:0045471) |
| 0.0 | 0.2 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.0 | 0.3 | GO:0018377 | N-terminal protein lipidation(GO:0006498) N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
| 0.0 | 3.0 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 1.3 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 1.1 | GO:0010043 | response to zinc ion(GO:0010043) |
| 0.0 | 1.1 | GO:0008542 | visual learning(GO:0008542) |
| 0.0 | 1.1 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.0 | 0.3 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.3 | GO:0048149 | adult feeding behavior(GO:0008343) behavioral response to ethanol(GO:0048149) |
| 0.0 | 0.4 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.7 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.0 | 0.4 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) |
| 0.0 | 0.2 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
| 0.0 | 0.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.3 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 1.4 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.0 | 1.0 | GO:0030865 | cortical cytoskeleton organization(GO:0030865) |
| 0.0 | 5.1 | GO:0050808 | synapse organization(GO:0050808) |
| 0.0 | 0.3 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 0.4 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.0 | 0.4 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.0 | 0.5 | GO:0097284 | hepatocyte apoptotic process(GO:0097284) |
| 0.0 | 0.2 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.0 | 1.0 | GO:0001706 | endoderm formation(GO:0001706) |
| 0.0 | 0.6 | GO:0051974 | negative regulation of telomerase activity(GO:0051974) |
| 0.0 | 0.9 | GO:0048701 | embryonic cranial skeleton morphogenesis(GO:0048701) |
| 0.0 | 0.8 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.0 | 2.7 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.1 | GO:1903795 | regulation of inorganic anion transmembrane transport(GO:1903795) |
| 0.0 | 0.2 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.0 | 0.2 | GO:0035814 | negative regulation of renal sodium excretion(GO:0035814) |
| 0.0 | 0.5 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 1.0 | GO:0030317 | sperm motility(GO:0030317) |
| 0.0 | 0.2 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.0 | 0.6 | GO:2000398 | regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398) |
| 0.0 | 0.2 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.3 | GO:1990173 | protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
| 0.0 | 3.0 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.0 | 0.2 | GO:0018126 | protein hydroxylation(GO:0018126) |
| 0.0 | 0.4 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.2 | GO:0050433 | regulation of catecholamine secretion(GO:0050433) |
| 0.0 | 1.6 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.2 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.0 | 0.6 | GO:0030262 | cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262) |
| 0.0 | 0.2 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.0 | 0.0 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.5 | GO:0043153 | photoperiodism(GO:0009648) entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 0.5 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.0 | 0.5 | GO:0042026 | protein refolding(GO:0042026) |
| 0.0 | 0.4 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.1 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.0 | 0.9 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) |
| 0.0 | 0.7 | GO:0031114 | negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114) |
| 0.0 | 0.5 | GO:0003016 | respiratory system process(GO:0003016) |
| 0.0 | 0.1 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 0.0 | 0.1 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.0 | 0.3 | GO:0002385 | organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385) |
| 0.0 | 0.1 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
| 0.0 | 0.2 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 1.7 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.0 | 0.5 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 0.0 | 1.8 | GO:0046330 | positive regulation of JNK cascade(GO:0046330) |
| 0.0 | 0.1 | GO:0043113 | receptor clustering(GO:0043113) |
| 0.0 | 0.1 | GO:1903301 | fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.0 | 1.2 | GO:0050670 | regulation of lymphocyte proliferation(GO:0050670) |
| 0.0 | 0.1 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.0 | 0.3 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 0.3 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.1 | GO:0090190 | positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.0 | 1.7 | GO:0045444 | fat cell differentiation(GO:0045444) |
| 0.0 | 0.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.5 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
| 0.0 | 0.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.0 | 0.4 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 0.0 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.0 | 0.2 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.0 | 0.4 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.2 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.3 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 1.0 | 4.1 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.8 | 13.6 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.7 | 2.7 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.5 | 3.8 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
| 0.5 | 3.0 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.5 | 11.8 | GO:0045259 | proton-transporting ATP synthase complex(GO:0045259) |
| 0.5 | 1.9 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.5 | 2.7 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.4 | 4.0 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.4 | 3.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.4 | 5.3 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.4 | 3.2 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.3 | 4.7 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.3 | 3.0 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.3 | 0.8 | GO:0005940 | septin ring(GO:0005940) |
| 0.3 | 3.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.3 | 1.1 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.2 | 0.5 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.2 | 4.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.2 | 1.1 | GO:1990761 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
| 0.2 | 1.5 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.2 | 0.2 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.2 | 0.6 | GO:0070449 | elongin complex(GO:0070449) |
| 0.2 | 1.0 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.2 | 3.8 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.2 | 0.6 | GO:1990879 | CST complex(GO:1990879) |
| 0.2 | 1.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.2 | 0.6 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
| 0.2 | 1.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.2 | 1.8 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.2 | 9.2 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.2 | 1.1 | GO:0038037 | G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) |
| 0.2 | 1.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.2 | 2.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 0.4 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.1 | 3.6 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.1 | 2.2 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.1 | 0.4 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.1 | 1.7 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 3.4 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.1 | 1.1 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 1.0 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 1.3 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.1 | 0.6 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 7.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.1 | 2.1 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 0.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.1 | 1.1 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 3.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.2 | GO:0031983 | vesicle lumen(GO:0031983) |
| 0.1 | 0.8 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.1 | 2.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.1 | 0.5 | GO:0032009 | early phagosome(GO:0032009) |
| 0.1 | 14.6 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.1 | 1.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 0.9 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 0.3 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.1 | 3.3 | GO:0005924 | cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055) |
| 0.1 | 0.2 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 3.5 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 0.5 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 1.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 0.5 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 4.9 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 0.8 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.1 | 4.4 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 3.0 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 2.0 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 0.2 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.2 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.0 | 1.2 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 0.4 | GO:0042599 | lamellar body(GO:0042599) |
| 0.0 | 0.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.4 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 0.4 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.0 | 0.4 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 3.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 1.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.1 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.0 | 0.3 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.6 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
| 0.0 | 0.5 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.3 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 0.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 1.6 | GO:0000152 | nuclear ubiquitin ligase complex(GO:0000152) |
| 0.0 | 0.9 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 0.1 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.0 | 0.9 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 1.4 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.3 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.0 | 0.8 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 2.2 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 1.0 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 1.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.9 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.8 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 1.4 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 2.9 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 0.6 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 2.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.5 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 1.3 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.8 | GO:0044439 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
| 0.0 | 6.9 | GO:0098794 | postsynapse(GO:0098794) |
| 0.0 | 0.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 1.4 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 53.6 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.0 | 0.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.0 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.3 | GO:0044432 | endoplasmic reticulum part(GO:0044432) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 12.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 1.9 | 5.7 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 1.5 | 4.6 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 1.4 | 8.5 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 1.2 | 5.0 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 1.1 | 7.7 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
| 1.0 | 2.9 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.8 | 4.1 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.8 | 4.7 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) mercury ion binding(GO:0045340) |
| 0.7 | 3.5 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.6 | 1.9 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.6 | 9.8 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.6 | 9.6 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.6 | 2.8 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.5 | 2.7 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.5 | 4.1 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.5 | 1.5 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.5 | 5.7 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.4 | 1.3 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
| 0.4 | 2.1 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.4 | 1.2 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
| 0.4 | 2.9 | GO:0032795 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
| 0.4 | 1.2 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 0.4 | 2.7 | GO:0015288 | porin activity(GO:0015288) |
| 0.4 | 1.4 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.4 | 1.1 | GO:0031755 | endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755) |
| 0.3 | 1.4 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.3 | 1.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.3 | 1.0 | GO:0031403 | lithium ion binding(GO:0031403) |
| 0.3 | 5.3 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.3 | 2.0 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.3 | 4.4 | GO:0008430 | selenium binding(GO:0008430) |
| 0.3 | 3.8 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) receptor agonist activity(GO:0048018) |
| 0.3 | 3.6 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.3 | 1.2 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 1.1 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) |
| 0.3 | 3.3 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.3 | 1.1 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.3 | 6.2 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.3 | 1.6 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.3 | 1.1 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.2 | 2.4 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.2 | 4.4 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.2 | 3.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.2 | 2.2 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.2 | 0.6 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
| 0.2 | 3.9 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.2 | 2.5 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.2 | 5.5 | GO:0005112 | Notch binding(GO:0005112) |
| 0.2 | 1.5 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.2 | 0.5 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618) |
| 0.2 | 3.0 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.2 | 0.9 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
| 0.2 | 0.5 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.2 | 0.5 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.2 | 0.5 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.2 | 0.6 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.1 | 2.4 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.1 | 0.4 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
| 0.1 | 0.7 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.1 | 3.8 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.1 | 2.1 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.1 | 1.2 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 0.4 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 0.1 | 0.9 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.1 | 1.0 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
| 0.1 | 1.5 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) acylglycerol lipase activity(GO:0047372) |
| 0.1 | 0.2 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 2.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 2.5 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) |
| 0.1 | 1.1 | GO:0048185 | activin binding(GO:0048185) |
| 0.1 | 1.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 0.5 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 2.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.0 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 2.2 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 0.3 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.1 | 0.3 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.1 | 2.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 1.0 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 0.4 | GO:0035586 | purinergic receptor activity(GO:0035586) |
| 0.1 | 2.2 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.1 | 2.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 0.4 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.1 | 0.6 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
| 0.1 | 2.1 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.1 | 2.9 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 0.4 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.1 | 1.3 | GO:0031628 | opioid receptor binding(GO:0031628) |
| 0.1 | 2.3 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
| 0.1 | 0.5 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
| 0.1 | 0.7 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.1 | 0.6 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
| 0.1 | 6.9 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
| 0.1 | 1.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 1.9 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
| 0.1 | 0.8 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.1 | 1.5 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 0.4 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.1 | 2.1 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 4.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.5 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.1 | 0.3 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.1 | 2.5 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 0.1 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.1 | 0.8 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.1 | 0.3 | GO:0004104 | choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 0.1 | 0.4 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.1 | 0.6 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.1 | 14.4 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.1 | 1.0 | GO:0023026 | MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026) |
| 0.1 | 0.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 0.7 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 0.6 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.1 | 0.2 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.0 | 0.1 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.0 | 0.2 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
| 0.0 | 0.5 | GO:0034943 | acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409) |
| 0.0 | 0.4 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.6 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 2.0 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.3 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.2 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.0 | 0.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 0.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 7.8 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 1.1 | GO:0000217 | DNA secondary structure binding(GO:0000217) |
| 0.0 | 0.1 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.0 | 0.2 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.0 | 1.2 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 1.8 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.8 | GO:0045309 | protein phosphorylated amino acid binding(GO:0045309) |
| 0.0 | 1.1 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.2 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 0.2 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.0 | 0.1 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.0 | 0.3 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 0.0 | 1.0 | GO:0035591 | signaling adaptor activity(GO:0035591) |
| 0.0 | 0.9 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.4 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 1.9 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.1 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.1 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 0.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.2 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 1.3 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 1.4 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.0 | 0.1 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.0 | 0.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.2 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 0.5 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.7 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.2 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.0 | 0.8 | GO:0035496 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062) |
| 0.0 | 0.5 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.3 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 4.1 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 0.1 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 1.7 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.3 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 1.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 1.1 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.9 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.7 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 3.3 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.7 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.1 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.0 | 0.5 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 0.4 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
| 0.0 | 0.3 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.4 | GO:0051117 | ATPase binding(GO:0051117) |
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