Motif ID: Ets1

Z-value: 0.849


Transcription factors associated with Ets1:

Gene SymbolEntrez IDGene Name
Ets1 ENSMUSG00000032035.9 Ets1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets1mm10_v2_chr9_+_32696005_32696121-0.524.2e-06Click!


Activity profile for motif Ets1.

activity profile for motif Ets1


Sorted Z-values histogram for motif Ets1

Sorted Z-values for motif Ets1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_5725639 9.856 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr6_+_5725812 8.161 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr15_-_66969616 8.096 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr8_-_71723308 6.989 ENSMUST00000125092.1
 Fcho1
FCH domain only 1
chr14_-_19977249 6.388 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr3_-_89245159 6.259 ENSMUST00000090924.6
 Trim46
tripartite motif-containing 46
chr3_-_89245005 5.856 ENSMUST00000107464.1
 Trim46
tripartite motif-containing 46
chr3_+_82358056 5.403 ENSMUST00000091014.4
 Map9
microtubule-associated protein 9
chr2_-_156312470 5.363 ENSMUST00000079125.6
 Scand1
SCAN domain-containing 1
chr7_+_44850393 5.245 ENSMUST00000136232.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr15_-_66812593 5.111 ENSMUST00000100572.3
 Sla
src-like adaptor
chr2_-_156392829 5.049 ENSMUST00000088578.2
 2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr7_-_4546567 5.028 ENSMUST00000065957.5
 Syt5
synaptotagmin V
chr7_-_127876777 4.877 ENSMUST00000106262.1
ENSMUST00000106263.1
ENSMUST00000054415.5
 Zfp668


zinc finger protein 668


chr14_-_19977040 4.823 ENSMUST00000159028.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr14_-_19977151 4.758 ENSMUST00000055100.7
ENSMUST00000162425.1
 Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr10_+_3366125 4.683 ENSMUST00000043374.5
 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr11_+_87592145 4.682 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
 Mtmr4


myotubularin related protein 4


chr3_+_98382438 4.589 ENSMUST00000056096.8
 Zfp697
zinc finger protein 697
chr14_-_31436028 4.534 ENSMUST00000091903.4
 Sh3bp5
SH3-domain binding protein 5 (BTK-associated)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 409 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 14.8 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.4 11.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.3 9.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
2.3 9.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.7 7.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.3 7.3 GO:0048268 clathrin coat assembly(GO:0048268)
1.0 6.8 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4 6.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.7 6.5 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.6 6.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.3 6.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
2.0 5.9 GO:0021649 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.1 5.8 GO:0003281 ventricular septum development(GO:0003281)
0.1 5.7 GO:0008542 visual learning(GO:0008542)
0.2 5.6 GO:0002076 osteoblast development(GO:0002076)
0.3 5.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 5.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.6 5.2 GO:0071569 protein ufmylation(GO:0071569)
0.4 5.2 GO:0000012 single strand break repair(GO:0000012)
1.3 5.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 189 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 21.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.6 17.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 15.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 10.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 9.6 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.9 9.2 GO:0071439 clathrin complex(GO:0071439)
0.1 9.0 GO:0030018 Z disc(GO:0030018)
0.2 8.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 8.3 GO:0031430 M band(GO:0031430)
0.3 7.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 7.4 GO:0005776 autophagosome(GO:0005776)
0.4 7.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.4 6.7 GO:0032279 asymmetric synapse(GO:0032279)
0.5 5.7 GO:0031931 TORC1 complex(GO:0031931)
0.0 5.7 GO:0031225 anchored component of membrane(GO:0031225)
0.9 5.4 GO:0000235 astral microtubule(GO:0000235)
0.0 5.4 GO:0043209 myelin sheath(GO:0043209)
0.4 5.2 GO:0031209 SCAR complex(GO:0031209)
1.3 5.0 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.4 5.0 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 254 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.6 18.0 GO:0045503 dynein light chain binding(GO:0045503)
0.9 15.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 13.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.3 13.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 12.5 GO:0008565 protein transporter activity(GO:0008565)
0.2 12.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.7 10.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 9.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 9.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 9.1 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) phospholipase C activity(GO:0004629) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.2 8.8 GO:0030276 clathrin binding(GO:0030276)
0.1 7.5 GO:0043130 ubiquitin binding(GO:0043130)
0.2 7.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 7.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.4 7.0 GO:0071253 connexin binding(GO:0071253)
0.3 6.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.8 5.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 5.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.1 5.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.6 5.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)