Motif ID: Ets2

Z-value: 1.151


Transcription factors associated with Ets2:

Gene SymbolEntrez IDGene Name
Ets2 ENSMUSG00000022895.8 Ets2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets2mm10_v2_chr16_+_95702044_957020940.381.1e-03Click!


Activity profile for motif Ets2.

activity profile for motif Ets2


Sorted Z-values histogram for motif Ets2

Sorted Z-values for motif Ets2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ets2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_5725639 18.010 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr17_+_3397189 14.598 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr6_+_5725812 14.596 ENSMUST00000115554.1
ENSMUST00000153942.1
Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr15_-_66969616 12.737 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr9_-_29411736 10.814 ENSMUST00000115236.1
Ntm
neurotrimin
chr7_-_4546567 10.690 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr2_-_156392829 10.624 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr13_-_59823072 10.302 ENSMUST00000071703.4
Zcchc6
zinc finger, CCHC domain containing 6
chr1_-_56969864 9.827 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_56969827 9.787 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr3_-_80802789 9.014 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_+_128058962 8.388 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr3_+_82358056 7.931 ENSMUST00000091014.4
Map9
microtubule-associated protein 9
chr2_-_5714490 7.554 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chrX_+_163908982 7.499 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr5_-_44799643 7.377 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr11_+_70647258 7.163 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr5_+_117133567 6.785 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
Taok3


TAO kinase 3


chr7_+_44850393 6.628 ENSMUST00000136232.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr13_+_109632760 6.367 ENSMUST00000135275.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr10_-_53379816 6.331 ENSMUST00000095691.5
Cep85l
centrosomal protein 85-like
chr1_+_152954966 6.241 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr15_-_43869993 6.112 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr16_-_4880284 6.049 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr10_+_127165118 5.911 ENSMUST00000006914.9
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr5_+_111733924 5.588 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr14_-_31436028 5.424 ENSMUST00000091903.4
Sh3bp5
SH3-domain binding protein 5 (BTK-associated)
chrX_+_157818435 5.412 ENSMUST00000087157.4
Klhl34
kelch-like 34
chr2_-_7395879 5.349 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr9_-_110476637 5.326 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr11_+_83302817 5.281 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr10_+_85386813 5.133 ENSMUST00000105307.1
ENSMUST00000020231.3
Btbd11

BTB (POZ) domain containing 11

chr7_+_24112314 5.066 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chrX_+_170009659 5.046 ENSMUST00000179760.1
Gm21887
predicted gene, 21887
chr2_-_168734236 5.017 ENSMUST00000109175.2
Atp9a
ATPase, class II, type 9A
chrX_+_170009892 4.969 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr11_+_29692937 4.949 ENSMUST00000102843.3
ENSMUST00000102842.3
ENSMUST00000078830.4
ENSMUST00000170731.1
Rtn4



reticulon 4



chr17_+_55445550 4.897 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr10_-_122047293 4.859 ENSMUST00000020322.5
ENSMUST00000081688.6
Srgap1

SLIT-ROBO Rho GTPase activating protein 1

chr10_+_79669410 4.772 ENSMUST00000020552.5
Tpgs1
tubulin polyglutamylase complex subunit 1
chr19_-_57360668 4.642 ENSMUST00000181921.1
B230217O12Rik
RIKEN cDNA B230217O12 gene
chr12_+_102948843 4.612 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chr16_-_3872378 4.606 ENSMUST00000090522.4
Zfp597
zinc finger protein 597
chr12_+_102949450 4.592 ENSMUST00000179002.1
Unc79
unc-79 homolog (C. elegans)
chr1_+_185454803 4.590 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr11_+_83302641 4.589 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr1_-_183297008 4.527 ENSMUST00000057062.5
Brox
BRO1 domain and CAAX motif containing
chr11_-_67922136 4.486 ENSMUST00000021288.3
ENSMUST00000108677.1
Usp43

ubiquitin specific peptidase 43

chr2_+_91650169 4.473 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr2_+_91650116 4.380 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr8_-_85840877 4.379 ENSMUST00000034140.7
Itfg1
integrin alpha FG-GAP repeat containing 1
chr19_-_40402267 4.367 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
Sorbs1



sorbin and SH3 domain containing 1



chr9_+_32224246 4.319 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr3_-_33844255 4.297 ENSMUST00000029222.5
Ccdc39
coiled-coil domain containing 39
chr2_+_104886318 4.205 ENSMUST00000111114.1
Ccdc73
coiled-coil domain containing 73
chr19_-_59943647 4.190 ENSMUST00000171986.1
Rab11fip2
RAB11 family interacting protein 2 (class I)
chr6_+_52714219 4.185 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr10_-_128498676 4.113 ENSMUST00000026428.3
Myl6b
myosin, light polypeptide 6B
chr1_+_176814660 4.108 ENSMUST00000056773.8
ENSMUST00000027785.8
Sdccag8

serologically defined colon cancer antigen 8

chr12_+_83688123 4.063 ENSMUST00000041806.5
Psen1
presenilin 1
chr5_-_144223516 4.038 ENSMUST00000085701.6
Tecpr1
tectonin beta-propeller repeat containing 1
chr12_-_64965496 4.008 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr4_+_43562672 3.958 ENSMUST00000167751.1
ENSMUST00000132631.1
Creb3

cAMP responsive element binding protein 3

chr3_-_127409014 3.897 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
Ank2


ankyrin 2, brain


chr5_+_34543365 3.879 ENSMUST00000101316.3
Sh3bp2
SH3-domain binding protein 2
chr1_-_67038824 3.831 ENSMUST00000119559.1
ENSMUST00000149996.1
ENSMUST00000027149.5
ENSMUST00000113979.3
Lancl1



LanC (bacterial lantibiotic synthetase component C)-like 1



chr3_+_98382538 3.828 ENSMUST00000178372.1
Zfp697
zinc finger protein 697
chr8_+_113635550 3.779 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chrX_+_163909132 3.754 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr8_-_71723308 3.738 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr10_+_59221945 3.728 ENSMUST00000182161.1
Sowahc
sosondowah ankyrin repeat domain family member C
chr2_+_121357714 3.691 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr3_+_98382438 3.666 ENSMUST00000056096.8
Zfp697
zinc finger protein 697
chr16_-_44139630 3.661 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr1_+_34678176 3.651 ENSMUST00000159747.2
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr17_+_72836678 3.635 ENSMUST00000045174.5
Ypel5
yippee-like 5 (Drosophila)
chr11_+_87592145 3.629 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr8_-_25785154 3.628 ENSMUST00000038498.8
Bag4
BCL2-associated athanogene 4
chr4_-_124851152 3.613 ENSMUST00000185036.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr10_-_30655859 3.606 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr17_-_24936894 3.596 ENSMUST00000115228.2
ENSMUST00000117509.1
ENSMUST00000121723.1
ENSMUST00000119115.1
ENSMUST00000121787.1
ENSMUST00000088345.5
ENSMUST00000120035.1
Mapk8ip3






mitogen-activated protein kinase 8 interacting protein 3






chr11_+_117654211 3.593 ENSMUST00000026658.6
Tnrc6c
trinucleotide repeat containing 6C
chr3_-_10440054 3.579 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chr9_+_32116040 3.578 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr9_-_27030010 3.508 ENSMUST00000034470.9
Vps26b
vacuolar protein sorting 26 homolog B (yeast)
chr8_+_72219726 3.472 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr6_+_86849488 3.469 ENSMUST00000089519.6
ENSMUST00000113668.1
Aak1

AP2 associated kinase 1

chr7_+_30413744 3.464 ENSMUST00000032800.9
Tyrobp
TYRO protein tyrosine kinase binding protein
chr4_+_44012661 3.425 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
Clta


clathrin, light polypeptide (Lca)


chr8_+_113635787 3.394 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chr3_-_127409044 3.382 ENSMUST00000182704.1
Ank2
ankyrin 2, brain
chr2_+_130406478 3.356 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr12_-_4038905 3.325 ENSMUST00000111178.1
Efr3b
EFR3 homolog B (S. cerevisiae)
chr4_-_145194999 3.322 ENSMUST00000036579.7
Vps13d
vacuolar protein sorting 13 D (yeast)
chr2_-_73386396 3.318 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr11_-_75454656 3.317 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr3_-_127408937 3.313 ENSMUST00000183095.1
ENSMUST00000182610.1
Ank2

ankyrin 2, brain

chr8_+_85060055 3.300 ENSMUST00000095220.3
Fbxw9
F-box and WD-40 domain protein 9
chr10_+_115384951 3.299 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr7_+_110018301 3.291 ENSMUST00000084731.3
Ipo7
importin 7
chr2_+_174076296 3.275 ENSMUST00000155000.1
ENSMUST00000134876.1
ENSMUST00000147038.1
Stx16


syntaxin 16


chr2_-_120970706 3.272 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr11_+_70764209 3.256 ENSMUST00000060444.5
Zfp3
zinc finger protein 3
chr5_-_143180721 3.230 ENSMUST00000164068.1
ENSMUST00000049861.4
ENSMUST00000165318.1
Rbak


RB-associated KRAB repressor


chrX_+_152178945 3.228 ENSMUST00000096275.4
Iqsec2
IQ motif and Sec7 domain 2
chr11_-_48817332 3.196 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41
chr5_-_99252839 3.138 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr10_+_70440643 3.114 ENSMUST00000105436.2
Fam13c
family with sequence similarity 13, member C
chr3_-_127408986 3.050 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
Ank2


ankyrin 2, brain


chr14_+_27238018 3.049 ENSMUST00000049206.5
Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr9_+_32224457 3.012 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr11_+_6200029 2.977 ENSMUST00000181545.1
A730071L15Rik
RIKEN cDNA A730071L15Rik gene
chr17_-_24936969 2.962 ENSMUST00000178969.1
ENSMUST00000115229.3
Mapk8ip3

mitogen-activated protein kinase 8 interacting protein 3

chr11_-_23498025 2.943 ENSMUST00000020529.6
Ahsa2
AHA1, activator of heat shock protein ATPase 2
chr17_+_29268788 2.941 ENSMUST00000064709.5
ENSMUST00000120346.1
BC004004

cDNA sequence BC004004

chr19_+_57361009 2.917 ENSMUST00000036407.4
Fam160b1
family with sequence similarity 160, member B1
chr9_+_56418624 2.914 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chrX_-_107816238 2.906 ENSMUST00000120722.1
2610002M06Rik
RIKEN cDNA 2610002M06 gene
chrX_-_75416533 2.904 ENSMUST00000033542.4
Mtcp1
mature T cell proliferation 1
chr2_+_127008711 2.903 ENSMUST00000110394.1
ENSMUST00000002063.8
Ap4e1

adaptor-related protein complex AP-4, epsilon 1

chr16_-_94526830 2.891 ENSMUST00000023615.6
Dscr3
Down syndrome critical region gene 3
chr11_-_20112876 2.883 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2
chr8_+_110079758 2.867 ENSMUST00000058804.8
Zfp612
zinc finger protein 612
chr7_-_127876777 2.859 ENSMUST00000106262.1
ENSMUST00000106263.1
ENSMUST00000054415.5
Zfp668


zinc finger protein 668


chr7_-_105399991 2.848 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr16_+_78301458 2.829 ENSMUST00000023572.7
Cxadr
coxsackie virus and adenovirus receptor
chr19_+_47854970 2.807 ENSMUST00000026050.7
Gsto1
glutathione S-transferase omega 1
chr4_+_149485215 2.801 ENSMUST00000124413.1
ENSMUST00000141293.1
Lzic

leucine zipper and CTNNBIP1 domain containing

chr7_-_110614761 2.790 ENSMUST00000166020.1
ENSMUST00000171218.1
ENSMUST00000033058.7
ENSMUST00000164759.1
Sbf2



SET binding factor 2



chrX_-_12762069 2.786 ENSMUST00000096495.4
ENSMUST00000076016.5
Med14

mediator complex subunit 14

chr2_-_148443543 2.784 ENSMUST00000099269.3
Cd93
CD93 antigen
chr1_+_43933980 2.779 ENSMUST00000087933.3
Tpp2
tripeptidyl peptidase II
chrY_+_90784738 2.748 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr19_-_7217549 2.738 ENSMUST00000039758.4
Cox8a
cytochrome c oxidase subunit VIIIa
chr2_+_168230597 2.734 ENSMUST00000099071.3
Mocs3
molybdenum cofactor synthesis 3
chr14_-_18239053 2.733 ENSMUST00000090543.5
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr5_+_29735991 2.716 ENSMUST00000012734.5
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr5_+_138085083 2.682 ENSMUST00000019660.4
ENSMUST00000066617.5
ENSMUST00000110963.1
Zkscan1


zinc finger with KRAB and SCAN domains 1


chr4_-_118409219 2.677 ENSMUST00000075406.5
Szt2
seizure threshold 2
chrX_-_103981242 2.674 ENSMUST00000121153.1
ENSMUST00000070705.4
Rlim

ring finger protein, LIM domain interacting

chr3_+_95160449 2.669 ENSMUST00000090823.1
ENSMUST00000090821.3
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr2_+_91202885 2.650 ENSMUST00000150403.1
ENSMUST00000002172.7
ENSMUST00000155418.1
Acp2


acid phosphatase 2, lysosomal


chr9_-_103219823 2.638 ENSMUST00000168142.1
Trf
transferrin
chr8_+_39005880 2.612 ENSMUST00000169034.1
Tusc3
tumor suppressor candidate 3
chr5_+_29735940 2.607 ENSMUST00000114839.1
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr4_+_44012638 2.603 ENSMUST00000107847.3
ENSMUST00000170241.1
Clta

clathrin, light polypeptide (Lca)

chr16_+_78301673 2.597 ENSMUST00000114229.2
Cxadr
coxsackie virus and adenovirus receptor
chr12_+_76533540 2.584 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr7_+_12834743 2.575 ENSMUST00000004614.8
Zfp110
zinc finger protein 110
chr9_-_79793378 2.566 ENSMUST00000034878.5
Tmem30a
transmembrane protein 30A
chr16_+_3872368 2.565 ENSMUST00000151988.1
Naa60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr3_+_129532386 2.562 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chrX_+_7722214 2.548 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
Wdr45





WD repeat domain 45





chr4_-_3574844 2.540 ENSMUST00000029891.5
Tmem68
transmembrane protein 68
chr7_-_143740316 2.519 ENSMUST00000119499.1
Osbpl5
oxysterol binding protein-like 5
chr4_+_45972233 2.509 ENSMUST00000102929.1
Tdrd7
tudor domain containing 7
chr5_+_122391878 2.501 ENSMUST00000102525.4
Arpc3
actin related protein 2/3 complex, subunit 3
chr18_+_30272747 2.495 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
Pik3c3


phosphoinositide-3-kinase, class 3


chr19_+_4231899 2.494 ENSMUST00000025773.3
Pold4
polymerase (DNA-directed), delta 4
chr13_+_119462752 2.488 ENSMUST00000026519.8
4833420G17Rik
RIKEN cDNA 4833420G17 gene
chr16_-_11176056 2.468 ENSMUST00000142389.1
ENSMUST00000138185.1
Zc3h7a

zinc finger CCCH type containing 7 A

chr11_-_68871848 2.468 ENSMUST00000101017.2
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr15_-_79141197 2.465 ENSMUST00000169604.1
1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr1_+_87755870 2.457 ENSMUST00000144047.1
ENSMUST00000027512.6
ENSMUST00000113186.1
ENSMUST00000113190.2
Atg16l1



autophagy related 16-like 1 (S. cerevisiae)



chr16_-_44139003 2.444 ENSMUST00000124102.1
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr11_-_118401826 2.442 ENSMUST00000106290.3
ENSMUST00000043722.3
Lgals3bp

lectin, galactoside-binding, soluble, 3 binding protein

chr1_-_190911728 2.434 ENSMUST00000159066.1
ENSMUST00000061611.8
Rps6kc1

ribosomal protein S6 kinase polypeptide 1

chr9_+_57589442 2.406 ENSMUST00000053230.6
Ulk3
unc-51-like kinase 3
chr6_+_52713729 2.397 ENSMUST00000080723.4
ENSMUST00000149588.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr9_-_79793507 2.396 ENSMUST00000120690.1
Tmem30a
transmembrane protein 30A
chr2_-_120353094 2.393 ENSMUST00000028752.7
ENSMUST00000102501.3
Vps39

vacuolar protein sorting 39 (yeast)

chr15_+_78430086 2.388 ENSMUST00000162808.1
Kctd17
potassium channel tetramerisation domain containing 17
chr15_+_9140527 2.380 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2
chr11_-_23497867 2.366 ENSMUST00000128559.1
ENSMUST00000147157.1
ENSMUST00000109539.1
Ahsa2


AHA1, activator of heat shock protein ATPase 2


chr14_+_55591708 2.361 ENSMUST00000019443.8
Rnf31
ring finger protein 31
chr16_+_17405981 2.351 ENSMUST00000023449.8
Snap29
synaptosomal-associated protein 29
chr16_-_44139196 2.345 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr10_-_9901079 2.332 ENSMUST00000141722.1
Stxbp5
syntaxin binding protein 5 (tomosyn)
chr11_+_117654798 2.274 ENSMUST00000106344.1
Tnrc6c
trinucleotide repeat containing 6C
chr7_+_35802593 2.258 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr7_+_24907618 2.253 ENSMUST00000151121.1
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr7_-_31042078 2.221 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
Fxyd5






FXYD domain-containing ion transport regulator 5






chr15_-_12592556 2.213 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr14_+_65969714 2.207 ENSMUST00000153460.1
Clu
clusterin
chr13_+_80886095 2.207 ENSMUST00000161441.1
Arrdc3
arrestin domain containing 3
chr2_-_91183818 2.198 ENSMUST00000075269.3
ENSMUST00000111371.1
ENSMUST00000111372.1
ENSMUST00000111381.2
ENSMUST00000077941.6
ENSMUST00000066473.5
Madd





MAP-kinase activating death domain





chr8_+_39005827 2.186 ENSMUST00000167992.1
Tusc3
tumor suppressor candidate 3
chr11_+_62551167 2.167 ENSMUST00000019649.3
Ubb
ubiquitin B
chr9_-_44965519 2.154 ENSMUST00000125642.1
ENSMUST00000117506.1
ENSMUST00000117549.1
Ube4a


ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)


chr16_+_56075399 2.153 ENSMUST00000089362.2
ENSMUST00000089360.3
ENSMUST00000049128.6
Senp7


SUMO1/sentrin specific peptidase 7


chr7_+_24902912 2.120 ENSMUST00000117796.1
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr11_-_83302586 2.113 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr7_+_129591859 2.109 ENSMUST00000084519.5
Wdr11
WD repeat domain 11
chr1_-_161131428 2.108 ENSMUST00000111611.1
Klhl20
kelch-like 20
chr1_+_85650008 2.104 ENSMUST00000054279.8
ENSMUST00000147552.1
ENSMUST00000153574.1
ENSMUST00000150967.1
Sp100



nuclear antigen Sp100



chr5_-_143269958 2.102 ENSMUST00000161448.1
Zfp316
zinc finger protein 316
chr7_+_44836286 2.097 ENSMUST00000033015.7
Il4i1
interleukin 4 induced 1
chr1_-_182341585 2.094 ENSMUST00000051431.4
Fbxo28
F-box protein 28
chr7_+_80269632 2.089 ENSMUST00000032749.5
Vps33b
vacuolar protein sorting 33B (yeast)
chr4_+_103313806 2.081 ENSMUST00000035780.3
Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0019085 early viral transcription(GO:0019085)
1.6 6.6 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
1.5 13.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.4 5.4 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
1.3 2.7 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
1.3 4.0 GO:0019043 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043)
1.3 6.4 GO:0030259 lipid glycosylation(GO:0030259)
1.3 12.7 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
1.2 19.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.1 3.3 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
1.1 7.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.0 4.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.0 2.9 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
1.0 2.9 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.9 9.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.9 3.6 GO:0090365 regulation of mRNA modification(GO:0090365)
0.8 0.8 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.8 2.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.8 3.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.8 5.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.8 4.1 GO:0015871 choline transport(GO:0015871) regulation of resting membrane potential(GO:0060075)
0.7 2.2 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.7 2.2 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.7 4.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.7 38.1 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.7 2.8 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.7 2.7 GO:0018307 enzyme active site formation(GO:0018307)
0.6 5.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.6 1.9 GO:0070488 neutrophil aggregation(GO:0070488)
0.6 1.9 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.6 3.1 GO:0042117 monocyte activation(GO:0042117)
0.6 2.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.6 4.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.5 2.2 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.5 2.7 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.5 4.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.5 2.6 GO:0048102 autophagic cell death(GO:0048102)
0.5 1.6 GO:0006624 vacuolar protein processing(GO:0006624)
0.5 2.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.5 9.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.5 6.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.5 22.2 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.5 2.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 1.7 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.4 1.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.4 1.3 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.4 6.7 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.4 2.5 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.4 4.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.4 1.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.4 1.5 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.4 2.2 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.4 2.9 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.4 13.2 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.4 5.9 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.4 2.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 1.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.4 1.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 11.2 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.4 6.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.3 1.0 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.3 1.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 2.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 1.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 1.6 GO:0070166 enamel mineralization(GO:0070166)
0.3 2.6 GO:0097460 ferrous iron import into cell(GO:0097460)
0.3 3.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.3 4.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.3 5.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 3.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.3 1.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.3 1.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 2.5 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.3 1.5 GO:0015867 ATP transport(GO:0015867)
0.3 2.0 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.3 1.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 1.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 5.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 1.0 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.2 1.4 GO:1990564 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 2.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 2.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 1.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.2 4.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 2.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 5.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 3.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.2 4.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.2 1.7 GO:0030049 muscle filament sliding(GO:0030049)
0.2 0.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 38.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.2 0.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.7 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 2.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 7.9 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.2 0.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 6.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.8 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 1.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.2 5.3 GO:0007032 endosome organization(GO:0007032)
0.1 2.7 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 7.9 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 1.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.2 GO:0046415 urate metabolic process(GO:0046415)
0.1 2.1 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 1.5 GO:0006829 zinc II ion transport(GO:0006829)
0.1 2.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 2.5 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 2.0 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.1 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 8.2 GO:0060976 coronary vasculature development(GO:0060976)
0.1 1.4 GO:0070995 NADPH oxidation(GO:0070995)
0.1 1.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.3 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 2.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.5 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 2.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 5.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 1.8 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 1.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 0.9 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.1 0.9 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 1.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 2.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.6 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.1 0.8 GO:0006903 vesicle targeting(GO:0006903)
0.1 2.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 0.4 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.1 1.0 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 3.2 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 8.3 GO:0030010 establishment of cell polarity(GO:0030010)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.1 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.1 2.5 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.3 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 2.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.0 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 2.7 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 0.2 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.1 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 4.3 GO:0031123 RNA 3'-end processing(GO:0031123)
0.1 6.0 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.4 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 2.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.6 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 1.0 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.7 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 3.3 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 1.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 1.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.8 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 6.3 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 1.8 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 7.7 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 3.7 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.3 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 3.1 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.9 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 1.7 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.9 GO:0031589 cell-substrate adhesion(GO:0031589)
0.0 0.2 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.6 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0005899 insulin receptor complex(GO:0005899)
1.4 4.1 GO:0070765 gamma-secretase complex(GO:0070765)
1.3 7.9 GO:0000235 astral microtubule(GO:0000235)
1.2 11.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.2 11.6 GO:0071439 clathrin complex(GO:0071439)
1.1 29.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.8 6.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.8 2.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.8 2.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.7 10.7 GO:0031045 dense core granule(GO:0031045)
0.7 2.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.6 1.9 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.6 6.6 GO:0031931 TORC1 complex(GO:0031931)
0.6 3.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.6 2.4 GO:0071797 LUBAC complex(GO:0071797)
0.6 13.6 GO:0031430 M band(GO:0031430)
0.5 2.9 GO:0070847 core mediator complex(GO:0070847)
0.5 2.4 GO:0030897 HOPS complex(GO:0030897)
0.5 2.8 GO:0005774 vacuolar membrane(GO:0005774)
0.4 9.0 GO:0032279 asymmetric synapse(GO:0032279)
0.4 3.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 5.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 4.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 4.7 GO:0032584 growth cone membrane(GO:0032584)
0.4 12.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.4 2.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4 2.8 GO:0070695 FHF complex(GO:0070695)
0.4 15.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.4 2.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.4 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 2.5 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.4 2.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3 1.3 GO:0019815 B cell receptor complex(GO:0019815)
0.3 2.6 GO:0097433 dense body(GO:0097433) HFE-transferrin receptor complex(GO:1990712)
0.3 4.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 0.6 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.3 19.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 2.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.3 6.6 GO:0030673 axolemma(GO:0030673)
0.3 17.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 2.5 GO:0005869 dynactin complex(GO:0005869)
0.2 1.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.2 2.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 3.5 GO:0000421 autophagosome membrane(GO:0000421)
0.2 4.1 GO:0034451 centriolar satellite(GO:0034451)
0.2 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.8 GO:0097441 basilar dendrite(GO:0097441)
0.1 6.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.4 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.3 GO:0038201 TOR complex(GO:0038201)
0.1 1.8 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 2.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 1.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 11.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 5.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 12.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 10.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.4 GO:0014704 intercalated disc(GO:0014704)
0.1 1.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.4 GO:0072487 MSL complex(GO:0072487)
0.1 0.3 GO:0005745 m-AAA complex(GO:0005745)
0.1 6.5 GO:0055037 recycling endosome(GO:0055037)
0.1 0.9 GO:0001527 microfibril(GO:0001527)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.4 GO:0030904 retromer complex(GO:0030904)
0.1 1.3 GO:0005605 basal lamina(GO:0005605)
0.1 13.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.9 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 4.3 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 4.0 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 4.1 GO:0031514 motile cilium(GO:0031514)
0.0 1.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 4.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 2.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.5 GO:0005770 late endosome(GO:0005770)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 2.8 GO:0043209 myelin sheath(GO:0043209)
0.0 2.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 4.5 GO:0005768 endosome(GO:0005768)
0.0 1.9 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 1.2 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 32.6 GO:0045503 dynein light chain binding(GO:0045503)
1.9 9.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
1.5 9.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.1 5.4 GO:0086080 connexin binding(GO:0071253) protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.0 4.9 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.9 2.8 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.9 3.7 GO:0004111 creatine kinase activity(GO:0004111)
0.8 2.3 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.7 2.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.7 2.8 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.7 6.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.6 2.5 GO:0070012 oligopeptidase activity(GO:0070012)
0.6 2.8 GO:0001849 complement component C1q binding(GO:0001849)
0.5 2.7 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.5 3.3 GO:0070728 leucine binding(GO:0070728)
0.5 2.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.5 19.0 GO:0045296 cadherin binding(GO:0045296)
0.5 1.5 GO:0015217 ADP transmembrane transporter activity(GO:0015217) coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.5 7.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.5 2.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.5 13.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 2.1 GO:0019961 interferon binding(GO:0019961)
0.4 22.6 GO:0030276 clathrin binding(GO:0030276)
0.4 2.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.4 1.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 2.8 GO:0030274 LIM domain binding(GO:0030274)
0.4 11.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.4 4.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 6.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.4 2.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.4 1.9 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.4 1.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 1.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 9.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 1.9 GO:0050786 arachidonic acid binding(GO:0050544) RAGE receptor binding(GO:0050786)
0.3 1.9 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.3 1.9 GO:0016936 galactoside binding(GO:0016936)
0.3 6.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.3 3.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 0.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 5.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.3 27.8 GO:0008565 protein transporter activity(GO:0008565)
0.2 1.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 5.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 2.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 4.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 0.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 8.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 1.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 4.7 GO:0051787 misfolded protein binding(GO:0051787)
0.2 2.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 22.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 2.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 1.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 2.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 4.1 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 2.6 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.2 1.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 7.1 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.1 1.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 5.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.4 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 2.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 1.4 GO:0070628 proteasome binding(GO:0070628)
0.1 3.7 GO:0045502 dynein binding(GO:0045502)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 4.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.7 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 3.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.2 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 5.9 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.6 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 2.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 6.7 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 3.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 5.8 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.4 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.1 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.9 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 7.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 13.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 5.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 8.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 6.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.8 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 3.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 2.0 GO:0008083 growth factor activity(GO:0008083)
0.0 2.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.8 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0005507 copper ion binding(GO:0005507)
0.0 1.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)