Motif ID: Etv3_Erf_Fev_Elk4_Elk1_Elk3

Z-value: 0.829

Transcription factors associated with Etv3_Erf_Fev_Elk4_Elk1_Elk3:

Gene SymbolEntrez IDGene Name
Elk1 ENSMUSG00000009406.7 Elk1
Elk3 ENSMUSG00000008398.8 Elk3
Elk4 ENSMUSG00000026436.9 Elk4
Erf ENSMUSG00000040857.9 Erf
Etv3 ENSMUSG00000003382.12 Etv3
Fev ENSMUSG00000055197.4 Fev

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elk1mm10_v2_chrX_-_20950597_209506130.792.6e-16Click!
Erfmm10_v2_chr7_-_25250720_25250761-0.564.6e-07Click!
Elk4mm10_v2_chr1_+_132007606_1320076340.397.4e-04Click!
Elk3mm10_v2_chr10_-_93310963_93310989-0.353.3e-03Click!
Etv3mm10_v2_chr3_+_87525572_875256430.244.8e-02Click!


Activity profile for motif Etv3_Erf_Fev_Elk4_Elk1_Elk3.

activity profile for motif Etv3_Erf_Fev_Elk4_Elk1_Elk3


Sorted Z-values histogram for motif Etv3_Erf_Fev_Elk4_Elk1_Elk3

Sorted Z-values for motif Etv3_Erf_Fev_Elk4_Elk1_Elk3



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv3_Erf_Fev_Elk4_Elk1_Elk3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_163602331 9.098 ENSMUST00000152135.1
 Ttpal
tocopherol (alpha) transfer protein-like
chr2_-_156392829 8.873 ENSMUST00000088578.2
 2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr8_-_69791170 7.494 ENSMUST00000131784.1
 Zfp866
zinc finger protein 866
chr9_-_18473559 7.226 ENSMUST00000034647.4
 Zfp558
zinc finger protein 558
chr5_-_3803081 7.099 ENSMUST00000043551.6
 Ankib1
ankyrin repeat and IBR domain containing 1
chr7_-_4546567 6.840 ENSMUST00000065957.5
 Syt5
synaptotagmin V
chr7_+_122067164 6.838 ENSMUST00000033158.4
 Ubfd1
ubiquitin family domain containing 1
chr6_+_8259288 6.530 ENSMUST00000159335.1
 Gm16039
predicted gene 16039
chr2_-_156312470 6.498 ENSMUST00000079125.6
 Scand1
SCAN domain-containing 1
chr12_-_84970814 6.159 ENSMUST00000165886.1
ENSMUST00000167448.1
ENSMUST00000043169.7
 Arel1


apoptosis resistant E3 ubiquitin protein ligase 1


chr11_+_6200029 6.147 ENSMUST00000181545.1
 A730071L15Rik
RIKEN cDNA A730071L15Rik gene
chr6_+_86849488 6.120 ENSMUST00000089519.6
ENSMUST00000113668.1
 Aak1

AP2 associated kinase 1

chr1_+_118389058 6.021 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
 Clasp1



CLIP associating protein 1



chr11_+_54522872 5.989 ENSMUST00000108895.1
ENSMUST00000101206.3
 Rapgef6

Rap guanine nucleotide exchange factor (GEF) 6

chr3_-_89160155 5.936 ENSMUST00000029686.3
 Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr2_-_73312701 5.931 ENSMUST00000058615.9
 Cir1
corepressor interacting with RBPJ, 1
chr12_-_64965496 5.917 ENSMUST00000021331.7
 Klhl28
kelch-like 28
chr2_+_168230597 5.860 ENSMUST00000099071.3
 Mocs3
molybdenum cofactor synthesis 3
chr16_-_87432597 5.809 ENSMUST00000039449.7
 Ltn1
listerin E3 ubiquitin protein ligase 1
chr11_+_87592145 5.641 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
 Mtmr4


myotubularin related protein 4



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 412 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.9 14.7 GO:0006266 DNA ligation(GO:0006266)
0.3 13.4 GO:0036465 synaptic vesicle recycling(GO:0036465)
1.6 13.1 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 12.2 GO:0003281 ventricular septum development(GO:0003281)
0.8 12.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.5 10.4 GO:0030033 microvillus assembly(GO:0030033)
0.5 9.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
3.2 9.5 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.6 9.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.4 8.4 GO:0002076 osteoblast development(GO:0002076)
2.0 8.0 GO:0044565 dendritic cell proliferation(GO:0044565)
0.6 7.8 GO:0030157 pancreatic juice secretion(GO:0030157)
0.3 7.8 GO:0006829 zinc II ion transport(GO:0006829)
2.5 7.6 GO:0019085 early viral transcription(GO:0019085)
1.9 7.6 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.7 7.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.2 7.3 GO:0048278 vesicle docking(GO:0048278)
0.2 7.2 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.2 7.1 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 188 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 21.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.5 17.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.3 16.5 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 16.0 GO:0005794 Golgi apparatus(GO:0005794)
0.1 14.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
1.9 13.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
2.6 12.9 GO:1990745 EARP complex(GO:1990745)
0.2 12.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.5 12.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.1 11.2 GO:0071439 clathrin complex(GO:0071439)
0.9 10.3 GO:0031931 TORC1 complex(GO:0031931)
0.1 9.9 GO:0005769 early endosome(GO:0005769)
0.1 9.7 GO:0005802 trans-Golgi network(GO:0005802)
0.1 9.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.8 9.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 9.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
1.2 7.5 GO:0097427 microtubule bundle(GO:0097427)
0.8 7.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 7.3 GO:0016324 apical plasma membrane(GO:0016324)
0.5 6.9 GO:0017119 Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 276 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 31.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 22.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 19.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.3 18.0 GO:0030276 clathrin binding(GO:0030276)
0.7 14.6 GO:0070628 proteasome binding(GO:0070628)
0.2 14.1 GO:0019905 syntaxin binding(GO:0019905)
0.1 12.7 GO:0017124 SH3 domain binding(GO:0017124)
2.5 12.3 GO:0071253 connexin binding(GO:0071253)
0.3 11.0 GO:0070063 RNA polymerase binding(GO:0070063)
0.7 10.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 9.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 8.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 8.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.2 7.7 GO:0050681 androgen receptor binding(GO:0050681)
0.3 7.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 7.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.3 7.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 7.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 7.0 GO:0008432 JUN kinase binding(GO:0008432)
0.4 6.7 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)