Motif ID: Figla

Z-value: 0.695


Transcription factors associated with Figla:

Gene SymbolEntrez IDGene Name
Figla ENSMUSG00000030001.3 Figla



Activity profile for motif Figla.

activity profile for motif Figla


Sorted Z-values histogram for motif Figla

Sorted Z-values for motif Figla



Network of associatons between targets according to the STRING database.



First level regulatory network of Figla

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_164769892 9.355 ENSMUST00000088248.6
ENSMUST00000001439.6
 Ube2c

ubiquitin-conjugating enzyme E2C

chr7_+_19094594 9.164 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr15_+_25622525 8.148 ENSMUST00000110457.1
ENSMUST00000137601.1
 Myo10

myosin X

chr12_+_109459843 7.868 ENSMUST00000173812.1
 Dlk1
delta-like 1 homolog (Drosophila)
chr1_-_119053339 7.535 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
 Gli2


GLI-Kruppel family member GLI2


chr7_-_144939823 7.319 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr14_-_20181773 6.725 ENSMUST00000024011.8
 Kcnk5
potassium channel, subfamily K, member 5
chr11_+_117809653 6.648 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
 Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr13_-_100786402 6.413 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
 Ccnb1


cyclin B1


chr5_+_123749696 6.142 ENSMUST00000031366.7
 Kntc1
kinetochore associated 1
chr2_+_168081004 6.016 ENSMUST00000052125.6
 Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr6_+_29694204 5.842 ENSMUST00000046750.7
ENSMUST00000115250.3
 Tspan33

tetraspanin 33

chr10_-_127341583 5.424 ENSMUST00000026474.3
 Gli1
GLI-Kruppel family member GLI1
chr2_-_122611238 5.349 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chrX_+_100730178 5.210 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr11_+_101316917 5.135 ENSMUST00000151385.1
 Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr10_+_26229707 5.086 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr15_-_78773452 5.032 ENSMUST00000018313.5
 Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_+_99864476 4.955 ENSMUST00000092694.3
 Gm11559
predicted gene 11559
chr14_+_27039001 4.902 ENSMUST00000035336.3
 Il17rd
interleukin 17 receptor D

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.4 GO:0051301 cell division(GO:0051301)
3.2 13.0 GO:0060032 notochord regression(GO:0060032)
0.1 11.0 GO:0048706 embryonic skeletal system development(GO:0048706)
1.9 9.4 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.8 9.2 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.6 8.3 GO:0048733 sebaceous gland development(GO:0048733)
0.1 8.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 7.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
2.5 7.6 GO:0036292 DNA rewinding(GO:0036292)
1.0 7.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 7.3 GO:0050873 brown fat cell differentiation(GO:0050873)
1.8 7.1 GO:0051311 spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311)
1.6 6.4 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.1 6.2 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.2 5.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
1.8 5.3 GO:0006601 creatine biosynthetic process(GO:0006601)
0.5 5.1 GO:0090527 actin filament reorganization(GO:0090527)
0.6 5.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 4.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 4.6 GO:0000910 cytokinesis(GO:0000910)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 13.0 GO:0097542 ciliary tip(GO:0097542)
0.4 10.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 9.0 GO:0005730 nucleolus(GO:0005730)
0.1 8.5 GO:0031594 neuromuscular junction(GO:0031594)
0.1 8.1 GO:0016459 myosin complex(GO:0016459)
0.1 8.0 GO:0030496 midbody(GO:0030496)
0.0 8.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 7.8 GO:0005938 cell cortex(GO:0005938)
0.2 7.6 GO:0043596 nuclear replication fork(GO:0043596)
0.2 7.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.8 7.1 GO:0072687 meiotic spindle(GO:0072687)
1.6 6.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.6 6.2 GO:0008537 proteasome activator complex(GO:0008537)
2.0 6.1 GO:1990423 RZZ complex(GO:1990423)
0.8 5.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 5.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 5.5 GO:0000790 nuclear chromatin(GO:0000790)
0.0 5.2 GO:0005884 actin filament(GO:0005884)
0.0 5.2 GO:0031225 anchored component of membrane(GO:0031225)
0.2 5.1 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 14.7 GO:0005525 GTP binding(GO:0005525)
0.1 11.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 9.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.4 8.4 GO:0070064 proline-rich region binding(GO:0070064)
0.2 8.1 GO:0030507 spectrin binding(GO:0030507)
0.6 7.6 GO:0036310 annealing helicase activity(GO:0036310)
1.3 6.4 GO:0005113 patched binding(GO:0005113)
0.8 6.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 6.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 5.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.5 5.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 5.2 GO:0003729 mRNA binding(GO:0003729)
1.7 5.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.6 4.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 4.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 4.8 GO:0005109 frizzled binding(GO:0005109)
0.3 4.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 4.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 4.2 GO:0002039 p53 binding(GO:0002039)