Motif ID: Fos

Z-value: 1.038


Transcription factors associated with Fos:

Gene SymbolEntrez IDGene Name
Fos ENSMUSG00000021250.7 Fos

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosmm10_v2_chr12_+_85473883_854738960.371.8e-03Click!


Activity profile for motif Fos.

activity profile for motif Fos


Sorted Z-values histogram for motif Fos

Sorted Z-values for motif Fos



Network of associatons between targets according to the STRING database.



First level regulatory network of Fos

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_13573927 23.073 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr18_+_82910863 16.502 ENSMUST00000171238.1
Zfp516
zinc finger protein 516
chr13_+_15463837 16.297 ENSMUST00000110510.3
Gli3
GLI-Kruppel family member GLI3
chr2_+_20737306 13.218 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr10_-_42583628 12.307 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr6_+_135362931 11.808 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr17_+_78508063 11.698 ENSMUST00000024880.9
Vit
vitrin
chr7_-_126799163 11.452 ENSMUST00000032934.5
Aldoa
aldolase A, fructose-bisphosphate
chr2_+_30078584 11.450 ENSMUST00000045246.7
Pkn3
protein kinase N3
chr18_+_35118880 11.092 ENSMUST00000042345.6
Ctnna1
catenin (cadherin associated protein), alpha 1
chr7_-_126799134 10.873 ENSMUST00000087566.4
Aldoa
aldolase A, fructose-bisphosphate
chr2_+_91257323 10.652 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr7_+_128523576 10.584 ENSMUST00000033136.7
Bag3
BCL2-associated athanogene 3
chr6_+_53573364 10.463 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr7_+_27486910 10.277 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr10_+_88091070 10.275 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr2_+_52038005 9.996 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr8_-_61591130 9.486 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld

palladin, cytoskeletal associated protein

chr19_+_36409719 9.426 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr9_+_78615501 9.376 ENSMUST00000093812.4
Cd109
CD109 antigen

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 140 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.6 23.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
2.2 22.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.6 16.5 GO:0009409 response to cold(GO:0009409)
5.4 16.3 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.6 14.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
2.5 12.3 GO:0021764 amygdala development(GO:0021764)
0.1 11.2 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
2.8 11.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.6 10.9 GO:0032060 bleb assembly(GO:0032060)
0.5 10.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4 10.6 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
3.4 10.3 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.7 9.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
2.3 9.4 GO:0072675 osteoclast fusion(GO:0072675)
0.2 9.3 GO:0070527 platelet aggregation(GO:0070527)
0.9 8.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
2.9 8.7 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.2 8.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.4 8.7 GO:0006825 copper ion transport(GO:0006825)
0.1 8.6 GO:0045444 fat cell differentiation(GO:0045444)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 24.3 GO:0044295 axonal growth cone(GO:0044295)
5.8 23.1 GO:0045098 type III intermediate filament(GO:0045098)
1.6 22.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 17.8 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.4 15.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 15.4 GO:0044449 contractile fiber part(GO:0044449)
0.4 15.3 GO:0016592 mediator complex(GO:0016592)
0.7 11.7 GO:0005614 interstitial matrix(GO:0005614)
1.0 11.1 GO:0005915 zonula adherens(GO:0005915)
0.4 9.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 9.4 GO:0031519 PcG protein complex(GO:0031519)
0.4 8.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
2.7 8.2 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 7.7 GO:0005802 trans-Golgi network(GO:0005802)
2.5 7.6 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 7.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.4 7.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.8 7.3 GO:0042587 glycogen granule(GO:0042587)
0.5 7.1 GO:0031932 TORC2 complex(GO:0031932)
1.0 6.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 27.5 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 22.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
5.6 22.4 GO:1990254 keratin filament binding(GO:1990254)
3.7 22.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 19.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.9 15.6 GO:0017166 vinculin binding(GO:0017166)
0.2 14.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 14.2 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.7 13.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 12.6 GO:0008270 zinc ion binding(GO:0008270)
0.3 11.5 GO:0004697 protein kinase C activity(GO:0004697)
0.1 11.2 GO:0003924 GTPase activity(GO:0003924)
0.1 11.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.7 10.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.8 10.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 10.0 GO:0001671 ATPase activator activity(GO:0001671)
0.5 9.8 GO:0035497 cAMP response element binding(GO:0035497)
0.5 9.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 9.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.3 8.9 GO:0004407 histone deacetylase activity(GO:0004407)