Motif ID: Foxa2_Foxa1
Z-value: 1.985


Transcription factors associated with Foxa2_Foxa1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Foxa1 | ENSMUSG00000035451.6 | Foxa1 |
Foxa2 | ENSMUSG00000037025.5 | Foxa2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Foxa2 | mm10_v2_chr2_-_148046896_148046991 | 0.45 | 7.9e-05 | Click! |
Foxa1 | mm10_v2_chr12_-_57546121_57546141 | 0.34 | 3.5e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 141 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 50.6 | GO:0042060 | wound healing(GO:0042060) |
15.7 | 47.2 | GO:0021759 | globus pallidus development(GO:0021759) |
1.4 | 46.5 | GO:0006270 | DNA replication initiation(GO:0006270) |
2.7 | 42.9 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
14.1 | 42.2 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
3.3 | 36.4 | GO:0042473 | outer ear morphogenesis(GO:0042473) |
9.0 | 36.1 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
1.3 | 35.8 | GO:0007638 | mechanosensory behavior(GO:0007638) |
3.2 | 35.0 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
8.5 | 34.1 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
3.0 | 30.0 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
4.8 | 28.9 | GO:0032488 | Cdc42 protein signal transduction(GO:0032488) |
9.1 | 27.2 | GO:1902524 | negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
3.2 | 25.6 | GO:0048625 | myoblast fate commitment(GO:0048625) |
4.6 | 23.2 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
7.4 | 22.3 | GO:0060023 | soft palate development(GO:0060023) |
7.1 | 21.2 | GO:0072076 | hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
1.0 | 20.8 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
2.0 | 20.1 | GO:0071763 | nuclear membrane organization(GO:0071763) |
1.7 | 19.2 | GO:0060539 | diaphragm development(GO:0060539) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 68 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 103.1 | GO:0031012 | extracellular matrix(GO:0031012) |
0.0 | 72.9 | GO:0005654 | nucleoplasm(GO:0005654) |
0.2 | 68.7 | GO:0005667 | transcription factor complex(GO:0005667) |
0.5 | 41.2 | GO:0005902 | microvillus(GO:0005902) |
1.3 | 40.1 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.4 | 35.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.3 | 34.1 | GO:0043198 | dendritic shaft(GO:0043198) |
7.5 | 30.0 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.7 | 27.8 | GO:0005719 | nuclear euchromatin(GO:0005719) |
2.8 | 25.6 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.1 | 22.6 | GO:0030426 | growth cone(GO:0030426) |
0.1 | 20.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
2.1 | 18.5 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 18.3 | GO:0043296 | apical junction complex(GO:0043296) |
0.1 | 15.5 | GO:0016324 | apical plasma membrane(GO:0016324) |
1.0 | 14.6 | GO:0042555 | MCM complex(GO:0042555) |
1.4 | 14.2 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
3.5 | 14.1 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
0.2 | 13.6 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.3 | 11.8 | GO:0030904 | retromer complex(GO:0030904) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 103 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 87.8 | GO:0001159 | core promoter proximal region DNA binding(GO:0001159) |
12.6 | 50.5 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
3.9 | 47.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
7.2 | 43.3 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
8.4 | 42.2 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
1.6 | 35.6 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.7 | 33.5 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
1.2 | 29.0 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 26.4 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
2.1 | 21.2 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.9 | 20.1 | GO:0005521 | lamin binding(GO:0005521) |
0.9 | 18.4 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.7 | 17.5 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
1.0 | 16.6 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
3.3 | 16.5 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 16.5 | GO:0051015 | actin filament binding(GO:0051015) |
1.6 | 16.0 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
3.2 | 15.9 | GO:0015186 | L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186) |
0.7 | 14.7 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.3 | 14.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |