Motif ID: Foxc1

Z-value: 0.733


Transcription factors associated with Foxc1:

Gene SymbolEntrez IDGene Name
Foxc1 ENSMUSG00000050295.2 Foxc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxc1mm10_v2_chr13_+_31806627_318066500.262.7e-02Click!


Activity profile for motif Foxc1.

activity profile for motif Foxc1


Sorted Z-values histogram for motif Foxc1

Sorted Z-values for motif Foxc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxc1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45311538 4.992 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chrY_+_1010543 4.091 ENSMUST00000091197.3
Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr12_-_73047179 3.444 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr14_-_48662740 3.362 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr6_+_47244359 3.326 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chr1_+_72824482 2.945 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr1_-_71653162 2.675 ENSMUST00000055226.6
Fn1
fibronectin 1
chr10_+_77864623 2.498 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr1_+_107511489 2.483 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr17_-_70851710 2.397 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr1_+_107511416 2.385 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chrX_-_102252154 2.317 ENSMUST00000050551.3
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr7_-_75308373 2.233 ENSMUST00000085164.5
Sv2b
synaptic vesicle glycoprotein 2 b
chr9_+_72806874 2.216 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr16_-_21947536 2.142 ENSMUST00000023562.7
Tmem41a
transmembrane protein 41a
chr8_+_106870827 2.084 ENSMUST00000176144.1
ENSMUST00000175987.1
Has3

hyaluronan synthase 3

chr13_-_54766553 2.054 ENSMUST00000036825.7
Sncb
synuclein, beta
chr2_+_4976113 2.020 ENSMUST00000167607.1
ENSMUST00000115010.2
Ucma

upper zone of growth plate and cartilage matrix associated

chr16_-_46155077 1.938 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chrX_-_102251852 1.934 ENSMUST00000101336.3
ENSMUST00000136277.1
Cited1

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

chr1_+_84839833 1.766 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr19_+_60144682 1.751 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chr13_+_53525703 1.703 ENSMUST00000081132.4
Gm5449
predicted pseudogene 5449
chr17_-_36951338 1.574 ENSMUST00000173540.1
Ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr18_+_78349754 1.536 ENSMUST00000164064.1
Gm6133
predicted gene 6133
chr4_-_43030440 1.498 ENSMUST00000135660.1
Stoml2
stomatin (Epb7.2)-like 2
chr6_-_55175019 1.497 ENSMUST00000003569.5
Inmt
indolethylamine N-methyltransferase
chr2_-_126709567 1.420 ENSMUST00000099423.2
Gm10774
predicted pseudogene 10774
chr9_-_71592265 1.402 ENSMUST00000169573.1
ENSMUST00000166843.1
ENSMUST00000163998.1
Myzap
Gcom1

myocardial zonula adherens protein
GRINL1A complex locus

chr7_+_16309577 1.400 ENSMUST00000002152.6
Bbc3
BCL2 binding component 3
chr3_+_94377432 1.374 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr15_-_102667749 1.357 ENSMUST00000075630.3
Atp5g2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr17_-_36951636 1.355 ENSMUST00000040402.7
ENSMUST00000174711.1
Ppp1r11

protein phosphatase 1, regulatory (inhibitor) subunit 11

chr5_-_149636164 1.289 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr15_+_80623499 1.288 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr12_-_69198419 1.287 ENSMUST00000021356.5
Dnaaf2
dynein, axonemal assembly factor 2
chr3_+_95124476 1.253 ENSMUST00000131597.1
ENSMUST00000005769.6
ENSMUST00000107227.1
Tmod4


tropomodulin 4


chr11_-_98625661 1.247 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr6_-_29212240 1.230 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr17_+_45686322 1.217 ENSMUST00000024734.7
Mrpl14
mitochondrial ribosomal protein L14
chr9_-_106891401 1.213 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr3_+_94377505 1.205 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr6_+_86371489 1.200 ENSMUST00000089558.5
Snrpg
small nuclear ribonucleoprotein polypeptide G
chr11_-_78550777 1.191 ENSMUST00000103242.4
Tmem97
transmembrane protein 97
chr6_-_42324554 1.175 ENSMUST00000095974.3
Fam131b
family with sequence similarity 131, member B
chr15_+_78597047 1.168 ENSMUST00000043069.5
Cyth4
cytohesin 4
chr5_-_97111565 1.143 ENSMUST00000112969.3
Paqr3
progestin and adipoQ receptor family member III
chr2_-_156839790 1.105 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr3_-_87263703 1.097 ENSMUST00000146512.1
Fcrls
Fc receptor-like S, scavenger receptor
chr4_-_40948196 1.095 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chr6_-_42324640 1.076 ENSMUST00000031891.8
ENSMUST00000143278.1
Fam131b

family with sequence similarity 131, member B

chr11_+_69935796 1.047 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr3_+_90079540 1.030 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
Tpm3


tropomyosin 3, gamma


chr1_+_189728264 1.027 ENSMUST00000097442.2
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr11_+_32300069 1.024 ENSMUST00000020535.1
Hbq1a
hemoglobin, theta 1A
chr18_-_33463615 1.013 ENSMUST00000051087.8
Nrep
neuronal regeneration related protein
chr3_-_87263518 0.998 ENSMUST00000090986.4
Fcrls
Fc receptor-like S, scavenger receptor
chr2_-_79908389 0.993 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr15_-_102257449 0.968 ENSMUST00000043172.8
Rarg
retinoic acid receptor, gamma
chr7_+_44816088 0.953 ENSMUST00000057195.9
ENSMUST00000107891.1
Nup62

nucleoporin 62

chr15_+_80255184 0.948 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr11_+_6415443 0.943 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr7_-_127026479 0.933 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr9_-_67049143 0.928 ENSMUST00000113687.1
ENSMUST00000113693.1
ENSMUST00000113701.1
ENSMUST00000034928.5
ENSMUST00000113685.3
ENSMUST00000030185.4
ENSMUST00000050905.9
ENSMUST00000113705.1
ENSMUST00000113697.1
ENSMUST00000113707.2
Tpm1









tropomyosin 1, alpha









chr15_-_76656905 0.919 ENSMUST00000176274.1
Cyhr1
cysteine and histidine rich 1
chr16_-_59632520 0.905 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr3_-_95282076 0.881 ENSMUST00000015855.7
Prune
prune homolog (Drosophila)
chr3_-_89998656 0.875 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr2_-_12301914 0.872 ENSMUST00000028106.4
Itga8
integrin alpha 8
chr7_-_142656018 0.865 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr15_-_102257306 0.864 ENSMUST00000135466.1
Rarg
retinoic acid receptor, gamma
chr11_+_3202612 0.851 ENSMUST00000110049.1
Eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr14_+_113314602 0.821 ENSMUST00000072359.6
Tpm3-rs7
tropomyosin 3, related sequence 7
chr8_-_25840440 0.820 ENSMUST00000110609.1
Ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr3_+_124321031 0.819 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr15_-_58034289 0.768 ENSMUST00000100655.3
9130401M01Rik
RIKEN cDNA 9130401M01 gene
chr11_-_102296618 0.764 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr2_-_172370506 0.756 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr11_+_73160403 0.723 ENSMUST00000006104.3
P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
chr1_-_87394721 0.720 ENSMUST00000113212.3
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr19_+_7268296 0.706 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr11_+_68968107 0.702 ENSMUST00000102606.3
ENSMUST00000018884.5
Slc25a35

solute carrier family 25, member 35

chr3_+_37312514 0.696 ENSMUST00000057975.7
ENSMUST00000108121.3
Bbs12

Bardet-Biedl syndrome 12 (human)

chr6_+_68161415 0.688 ENSMUST00000168090.1
Igkv1-115
immunoglobulin kappa variable 1-115
chr2_-_79908428 0.684 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr2_+_151542483 0.675 ENSMUST00000044011.5
Fkbp1a
FK506 binding protein 1a
chr5_+_8046077 0.660 ENSMUST00000088786.4
Sri
sorcin
chr13_-_18382041 0.659 ENSMUST00000139064.2
ENSMUST00000175703.2
Pou6f2

POU domain, class 6, transcription factor 2

chr17_-_57011271 0.642 ENSMUST00000002733.6
Gtf2f1
general transcription factor IIF, polypeptide 1
chr1_-_131097535 0.616 ENSMUST00000016672.4
Mapkapk2
MAP kinase-activated protein kinase 2
chr2_+_163994960 0.606 ENSMUST00000018470.3
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr2_-_103485068 0.605 ENSMUST00000111168.3
Cat
catalase
chr15_-_66948419 0.604 ENSMUST00000167817.1
Ndrg1
N-myc downstream regulated gene 1
chr13_+_37826225 0.592 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr5_+_98854434 0.582 ENSMUST00000031278.4
Bmp3
bone morphogenetic protein 3
chr1_+_34439851 0.576 ENSMUST00000027303.7
Imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr18_+_53245618 0.569 ENSMUST00000165032.1
Snx24
sorting nexing 24
chr12_+_105336922 0.567 ENSMUST00000180503.1
2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr8_-_41417042 0.567 ENSMUST00000033999.6
Frg1
FSHD region gene 1
chr18_+_33464163 0.551 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr13_-_107414742 0.537 ENSMUST00000061241.6
Apoo-ps
apolipoprotein O, pseudogene
chr16_+_20674111 0.526 ENSMUST00000151679.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr12_-_113422730 0.518 ENSMUST00000177715.1
ENSMUST00000103426.1
Ighm

immunoglobulin heavy constant mu

chr6_-_99096196 0.518 ENSMUST00000175886.1
Foxp1
forkhead box P1
chr2_+_30807826 0.512 ENSMUST00000041830.3
ENSMUST00000152374.1
Ntmt1

N-terminal Xaa-Pro-Lys N-methyltransferase 1

chr14_+_52016849 0.503 ENSMUST00000100638.2
Tmem253
transmembrane protein 253
chr15_-_97814830 0.476 ENSMUST00000121514.1
Hdac7
histone deacetylase 7
chr11_-_45944910 0.475 ENSMUST00000129820.1
Lsm11
U7 snRNP-specific Sm-like protein LSM11
chr8_-_105933832 0.449 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr1_-_74284636 0.442 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr11_-_96829483 0.442 ENSMUST00000167149.1
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr4_-_59783800 0.436 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chr1_+_163994866 0.422 ENSMUST00000111490.1
ENSMUST00000045694.7
Mettl18

methyltransferase like 18

chr6_+_55203381 0.398 ENSMUST00000053094.7
Fam188b
family with sequence similarity 188, member B
chr3_+_154597197 0.397 ENSMUST00000155385.1
ENSMUST00000029850.8
Cryz

crystallin, zeta

chr3_+_145987835 0.386 ENSMUST00000039517.6
Syde2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr15_+_6422240 0.377 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr2_-_181365306 0.372 ENSMUST00000108808.1
ENSMUST00000170190.1
ENSMUST00000127988.1
Arfrp1


ADP-ribosylation factor related protein 1


chr5_-_100038869 0.366 ENSMUST00000153442.1
Hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like
chr2_+_172370658 0.350 ENSMUST00000151511.1
ENSMUST00000116375.1
Cstf1

cleavage stimulation factor, 3' pre-RNA, subunit 1

chr2_+_35622010 0.342 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr8_+_69088646 0.342 ENSMUST00000006435.7
Atp6v1b2
ATPase, H+ transporting, lysosomal V1 subunit B2
chr1_+_74284930 0.333 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr1_+_75236439 0.318 ENSMUST00000082158.6
ENSMUST00000055223.7
Dnajb2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr4_+_117550326 0.317 ENSMUST00000037127.8
Eri3
exoribonuclease 3
chr1_+_120602405 0.313 ENSMUST00000079721.7
En1
engrailed 1
chr3_-_141982224 0.313 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr9_+_110419750 0.308 ENSMUST00000035061.6
Ngp
neutrophilic granule protein
chr4_+_100478806 0.298 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chr11_-_96829959 0.292 ENSMUST00000081775.5
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr7_-_89941084 0.277 ENSMUST00000075010.4
ENSMUST00000153470.1
l7Rn6

lethal, Chr 7, Rinchik 6

chr10_+_45577811 0.267 ENSMUST00000037044.6
Hace1
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr4_+_98923810 0.266 ENSMUST00000030289.2
Usp1
ubiquitin specific peptidase 1
chr19_+_53944870 0.261 ENSMUST00000025932.7
Shoc2
soc-2 (suppressor of clear) homolog (C. elegans)
chr13_+_65512678 0.261 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chrY_+_90843934 0.254 ENSMUST00000178550.1
Gm21742
predicted gene, 21742
chr15_+_88819584 0.239 ENSMUST00000024042.3
Creld2
cysteine-rich with EGF-like domains 2
chr14_-_31128924 0.238 ENSMUST00000064032.4
ENSMUST00000049732.5
ENSMUST00000090205.3
Smim4


small itegral membrane protein 4


chr10_-_14705459 0.237 ENSMUST00000149485.1
ENSMUST00000154132.1
Vta1

Vps20-associated 1 homolog (S. cerevisiae)

chrX_-_101222426 0.230 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr3_+_95160449 0.226 ENSMUST00000090823.1
ENSMUST00000090821.3
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr17_+_46254017 0.215 ENSMUST00000095262.4
Lrrc73
leucine rich repeat containing 73
chr7_+_19228334 0.210 ENSMUST00000063976.8
Opa3
optic atrophy 3
chr6_-_88045190 0.207 ENSMUST00000113596.1
ENSMUST00000113600.3
Rab7

RAB7, member RAS oncogene family

chr17_-_45686214 0.204 ENSMUST00000113523.2
Tmem63b
transmembrane protein 63b
chr9_-_83146601 0.201 ENSMUST00000162246.2
ENSMUST00000161796.2
Hmgn3

high mobility group nucleosomal binding domain 3

chr4_+_40948401 0.196 ENSMUST00000030128.5
Chmp5
charged multivesicular body protein 5
chr3_-_96197580 0.186 ENSMUST00000016087.3
Bola1
bolA-like 1 (E. coli)
chr11_+_101082565 0.182 ENSMUST00000001806.3
ENSMUST00000107308.3
Coasy

Coenzyme A synthase

chr4_+_98923845 0.175 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chr4_-_116627478 0.162 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp

nuclear autoantigenic sperm protein (histone-binding)

chr12_-_87443800 0.161 ENSMUST00000162961.1
Alkbh1
alkB, alkylation repair homolog 1 (E. coli)
chr3_+_61364507 0.150 ENSMUST00000049064.2
Rap2b
RAP2B, member of RAS oncogene family
chr7_+_83584910 0.128 ENSMUST00000039317.7
ENSMUST00000164944.1
Tmc3

transmembrane channel-like gene family 3

chr16_+_18248961 0.127 ENSMUST00000100099.3
Trmt2a
TRM2 tRNA methyltransferase 2A
chr11_-_96829904 0.106 ENSMUST00000107657.1
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr15_+_82016369 0.097 ENSMUST00000069530.6
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr4_-_42084291 0.094 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr5_+_119834663 0.094 ENSMUST00000018407.6
Tbx5
T-box 5
chr7_-_44892358 0.091 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr4_+_11123950 0.090 ENSMUST00000142297.1
Gm11827
predicted gene 11827
chr9_-_86880647 0.089 ENSMUST00000167014.1
Snap91
synaptosomal-associated protein 91
chr13_-_8871751 0.088 ENSMUST00000175958.1
Wdr37
WD repeat domain 37
chrX_+_101449078 0.074 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr13_-_34077992 0.071 ENSMUST00000056427.8
Tubb2a
tubulin, beta 2A class IIA
chr17_-_83631892 0.068 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr3_+_94837533 0.067 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr9_-_21037775 0.061 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr11_-_4594750 0.059 ENSMUST00000109943.3
Mtmr3
myotubularin related protein 3
chr16_+_18248866 0.047 ENSMUST00000115640.1
ENSMUST00000140206.1
Trmt2a

TRM2 tRNA methyltransferase 2A

chr7_-_51862216 0.042 ENSMUST00000169357.1
Fancf
Fanconi anemia, complementation group F
chr2_+_73312601 0.038 ENSMUST00000090811.4
ENSMUST00000112050.1
Scrn3

secernin 3

chr3_+_154597352 0.031 ENSMUST00000140644.1
ENSMUST00000144764.1
ENSMUST00000155232.1
Cryz


crystallin, zeta


chr2_+_127208358 0.020 ENSMUST00000103220.3
Snrnp200
small nuclear ribonucleoprotein 200 (U5)
chr9_-_103222063 0.019 ENSMUST00000170904.1
Trf
transferrin
chr9_-_51278540 0.011 ENSMUST00000114427.3
Gm684
predicted gene 684
chr5_-_97111589 0.009 ENSMUST00000069453.2
ENSMUST00000112968.1
Paqr3

progestin and adipoQ receptor family member III


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
1.1 4.3 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
1.0 5.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.9 2.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161)
0.8 3.4 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.7 2.1 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.7 3.3 GO:0071205 clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205)
0.5 1.5 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.5 1.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.4 1.2 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.4 2.6 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.4 1.4 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.3 1.3 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.3 0.9 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.3 4.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 0.7 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.2 1.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 2.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 0.8 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.2 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 1.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 3.8 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.2 0.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.2 0.9 GO:0046909 intermembrane transport(GO:0046909)
0.1 2.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.7 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 1.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.6 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 0.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.3 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 1.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 2.4 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 0.6 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.0 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1 0.6 GO:0009650 UV protection(GO:0009650)
0.1 0.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.9 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.2 GO:0061724 lipophagy(GO:0061724)
0.0 1.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 1.5 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 1.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 2.0 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.3 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.7 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.9 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 4.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.8 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.0 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.2 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 1.2 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 2.3 GO:0098792 xenophagy(GO:0098792)
0.0 2.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.7 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.5 GO:0009308 amine metabolic process(GO:0009308) response to toxic substance(GO:0009636)
0.0 0.5 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.6 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 1.8 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.5 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005577 fibrinogen complex(GO:0005577)
0.4 5.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 0.9 GO:1990037 Lewy body core(GO:1990037)
0.3 0.8 GO:0042585 germinal vesicle(GO:0042585)
0.2 3.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 2.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.0 GO:0044613 nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.5 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 1.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.8 GO:0048188 MLL3/4 complex(GO:0044666) Set1C/COMPASS complex(GO:0048188)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.1 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.4 GO:0032420 stereocilium(GO:0032420)
0.1 4.4 GO:0016234 inclusion body(GO:0016234)
0.1 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) alveolar lamellar body(GO:0097208)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 1.8 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 4.1 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 2.6 GO:0008142 oxysterol binding(GO:0008142)
0.5 4.3 GO:0050693 LBD domain binding(GO:0050693)
0.5 1.5 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.4 2.7 GO:0045340 mercury ion binding(GO:0045340)
0.4 2.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 5.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 2.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 1.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 0.9 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 1.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.0 GO:0051425 PTB domain binding(GO:0051425)
0.2 0.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 0.6 GO:0030519 snoRNP binding(GO:0030519)
0.2 0.9 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 0.5 GO:0071209 U7 snRNA binding(GO:0071209)
0.2 0.6 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
0.2 1.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.7 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.4 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.8 GO:1990188 euchromatin binding(GO:1990188)
0.1 4.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.6 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815)
0.1 2.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 4.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.7 GO:0048185 activin binding(GO:0048185)
0.1 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 4.0 GO:0002020 protease binding(GO:0002020)
0.0 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 2.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 5.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.2 GO:0008083 growth factor activity(GO:0008083)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 1.4 GO:0051117 ATPase binding(GO:0051117)
0.0 1.1 GO:0051087 chaperone binding(GO:0051087)