Motif ID: Foxc2

Z-value: 0.411


Transcription factors associated with Foxc2:

Gene SymbolEntrez IDGene Name
Foxc2 ENSMUSG00000046714.6 Foxc2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxc2mm10_v2_chr8_+_121116163_121116177-0.218.3e-02Click!


Activity profile for motif Foxc2.

activity profile for motif Foxc2


Sorted Z-values histogram for motif Foxc2

Sorted Z-values for motif Foxc2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxc2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 6.323 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr9_+_53850243 3.988 ENSMUST00000048485.5
Sln
sarcolipin
chr4_-_87806296 3.469 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr2_-_62483637 3.412 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr4_+_48049080 3.371 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr1_+_177444653 2.884 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr11_+_32000452 2.773 ENSMUST00000020537.2
ENSMUST00000109409.1
Nsg2

neuron specific gene family member 2

chr3_-_123672321 2.386 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr16_-_74411292 2.338 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr4_+_97777606 1.830 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr17_+_3532554 1.830 ENSMUST00000168560.1
Cldn20
claudin 20
chr11_+_32000496 1.733 ENSMUST00000093219.3
Nsg2
neuron specific gene family member 2
chr2_-_45110336 1.599 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr1_+_179546303 1.468 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr1_-_97977233 1.467 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr2_-_65529275 1.411 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chrX_+_163911401 1.271 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr12_-_108003414 1.263 ENSMUST00000109887.1
ENSMUST00000109891.2
Bcl11b

B cell leukemia/lymphoma 11B

chr4_-_87806276 1.238 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr17_+_70522083 1.187 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr13_+_42681513 1.167 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr8_+_66386292 1.138 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr19_+_44992127 1.124 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr2_-_73312701 1.116 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr3_-_146781351 1.098 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr4_+_102741287 1.053 ENSMUST00000097948.2
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_+_44849581 1.047 ENSMUST00000150335.1
ENSMUST00000107882.1
Akt1s1

AKT1 substrate 1 (proline-rich)

chr13_+_40859768 1.021 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr16_+_43363855 0.990 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr16_-_4880284 0.989 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr5_-_111761697 0.943 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr8_+_45658666 0.929 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr12_-_108003594 0.921 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr19_-_42086338 0.919 ENSMUST00000051772.8
Morn4
MORN repeat containing 4
chr2_-_77519565 0.900 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr1_+_43445736 0.859 ENSMUST00000086421.5
ENSMUST00000114744.1
Nck2

non-catalytic region of tyrosine kinase adaptor protein 2

chr7_+_44849216 0.855 ENSMUST00000054343.8
Akt1s1
AKT1 substrate 1 (proline-rich)
chr1_-_179546261 0.835 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr16_-_34263179 0.834 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr8_+_45658731 0.830 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr2_-_7395879 0.821 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr3_+_136670076 0.810 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr16_+_43364145 0.807 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr8_-_64205970 0.801 ENSMUST00000066166.4
Tll1
tolloid-like
chr14_+_61607455 0.785 ENSMUST00000051184.8
Kcnrg
potassium channel regulator
chr12_-_31950535 0.776 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chr12_-_31950210 0.751 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr18_-_54990124 0.741 ENSMUST00000064763.5
Zfp608
zinc finger protein 608
chr17_+_70522149 0.694 ENSMUST00000140728.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr16_-_34262945 0.682 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr10_+_60106452 0.675 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr6_+_8520008 0.674 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1

glucocorticoid induced transcript 1

chr9_-_101198999 0.665 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr7_-_44849075 0.660 ENSMUST00000047085.8
Tbc1d17
TBC1 domain family, member 17
chr7_+_82175156 0.655 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr4_-_118409219 0.649 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr7_+_24271568 0.649 ENSMUST00000032696.6
Zfp93
zinc finger protein 93
chr7_+_44848991 0.632 ENSMUST00000107885.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr11_-_101466222 0.622 ENSMUST00000040430.7
Vat1
vesicle amine transport protein 1 homolog (T californica)
chr12_-_31950170 0.597 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr13_-_30974023 0.575 ENSMUST00000021785.6
Exoc2
exocyst complex component 2
chr6_+_17491216 0.571 ENSMUST00000080469.5
Met
met proto-oncogene
chr8_+_93810832 0.559 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr10_-_41303171 0.556 ENSMUST00000043814.3
Fig4
FIG4 homolog (S. cerevisiae)
chr6_+_92940572 0.498 ENSMUST00000181145.1
ENSMUST00000181840.1
9530026P05Rik

RIKEN cDNA 9530026P05 gene

chr16_-_22657165 0.490 ENSMUST00000089925.3
Dgkg
diacylglycerol kinase, gamma
chr10_-_96409038 0.458 ENSMUST00000179683.1
Gm20091
predicted gene, 20091
chr3_+_94837533 0.457 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr7_+_27591513 0.457 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr14_-_24486994 0.442 ENSMUST00000026322.7
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr13_-_12464925 0.418 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr3_+_76075583 0.406 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr11_+_77765588 0.401 ENSMUST00000164315.1
Myo18a
myosin XVIIIA
chr4_+_148591482 0.389 ENSMUST00000006611.8
Srm
spermidine synthase
chr10_-_68278713 0.366 ENSMUST00000020106.7
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr3_+_68584154 0.365 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr5_-_122989086 0.362 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr5_+_25247344 0.348 ENSMUST00000114950.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr5_-_122989260 0.345 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr8_-_84237042 0.334 ENSMUST00000039480.5
Zswim4
zinc finger SWIM-type containing 4
chr12_-_101958148 0.331 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3



ataxin 3



chr3_+_94837702 0.320 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz


pogo transposable element with ZNF domain


chr7_+_27195781 0.316 ENSMUST00000108379.1
ENSMUST00000179391.1
BC024978

cDNA sequence BC024978

chr2_+_91730127 0.310 ENSMUST00000099712.3
ENSMUST00000111317.2
ENSMUST00000111316.2
ENSMUST00000045705.7
Ambra1



autophagy/beclin 1 regulator 1



chr7_-_34655500 0.308 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr4_+_114680769 0.301 ENSMUST00000146346.1
Gm12829
predicted gene 12829
chr11_+_29463735 0.289 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr5_-_115098295 0.285 ENSMUST00000100848.2
Gm10401
predicted gene 10401
chr9_-_21291124 0.279 ENSMUST00000086374.6
Cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr9_+_70679016 0.269 ENSMUST00000144537.1
Adam10
a disintegrin and metallopeptidase domain 10
chr5_-_122988533 0.268 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b

lysine (K)-specific demethylase 2B

chr9_+_70678950 0.265 ENSMUST00000067880.6
Adam10
a disintegrin and metallopeptidase domain 10
chr6_-_137571007 0.251 ENSMUST00000100841.2
Eps8
epidermal growth factor receptor pathway substrate 8
chr6_+_14901440 0.229 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr2_-_177267036 0.223 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr17_+_46161111 0.222 ENSMUST00000166563.1
Gtpbp2
GTP binding protein 2
chr2_+_143915273 0.221 ENSMUST00000103172.3
Dstn
destrin
chr4_+_102430047 0.192 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr9_+_70207342 0.182 ENSMUST00000034745.7
Myo1e
myosin IE
chr1_-_156036473 0.165 ENSMUST00000097527.3
ENSMUST00000027738.7
Tor1aip1

torsin A interacting protein 1

chr4_-_82885148 0.160 ENSMUST00000048430.3
Cer1
cerberus 1 homolog (Xenopus laevis)
chr17_+_46161021 0.154 ENSMUST00000024748.7
ENSMUST00000172170.1
Gtpbp2

GTP binding protein 2

chr12_-_54695885 0.147 ENSMUST00000067272.8
Eapp
E2F-associated phosphoprotein
chr18_+_61105561 0.128 ENSMUST00000025523.6
Csf1r
colony stimulating factor 1 receptor
chr5_+_32458974 0.106 ENSMUST00000015100.8
Ppp1cb
protein phosphatase 1, catalytic subunit, beta isoform
chr2_+_76675265 0.101 ENSMUST00000111920.1
Plekha3
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
chr3_-_65529355 0.096 ENSMUST00000099076.3
4931440P22Rik
RIKEN cDNA 4931440P22 gene
chr9_-_105521147 0.072 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr3_-_106167564 0.069 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr12_-_54695829 0.067 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
Eapp



E2F-associated phosphoprotein



chr6_+_34709610 0.049 ENSMUST00000031775.6
Cald1
caldesmon 1
chr1_+_156035705 0.049 ENSMUST00000111754.2
ENSMUST00000133152.1
Tor1aip2

torsin A interacting protein 2

chr1_+_9848270 0.039 ENSMUST00000171265.1
Sgk3
serum/glucocorticoid regulated kinase 3
chr1_-_156035891 0.021 ENSMUST00000126448.1
Tor1aip1
torsin A interacting protein 1
chr11_+_78465697 0.020 ENSMUST00000001126.3
Slc46a1
solute carrier family 46, member 1
chr11_-_107348130 0.018 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chrX_+_119927196 0.002 ENSMUST00000040961.2
ENSMUST00000113366.1
Pabpc5

poly(A) binding protein, cytoplasmic 5


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.0 4.0 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.8 2.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.5 1.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.5 3.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.5 4.7 GO:0007379 segment specification(GO:0007379)
0.5 6.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 2.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 1.4 GO:0046684 response to pyrethroid(GO:0046684)
0.3 0.8 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.3 1.6 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.9 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.2 4.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 1.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.0 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 1.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 0.6 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 2.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 1.5 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.9 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.6 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.5 GO:0042117 monocyte activation(GO:0042117)
0.1 1.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.6 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.4 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 2.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.1 0.5 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.2 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.6 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.4 GO:0060613 fat pad development(GO:0060613)
0.0 2.9 GO:0021766 hippocampus development(GO:0021766)
0.0 1.1 GO:0097320 membrane tubulation(GO:0097320)
0.0 1.4 GO:0060074 synapse maturation(GO:0060074)
0.0 0.2 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 2.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 1.3 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0001553 luteinization(GO:0001553)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0031931 TORC1 complex(GO:0031931)
0.2 4.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.8 GO:0005955 calcineurin complex(GO:0005955)
0.1 4.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.1 2.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 6.3 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.9 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.5 1.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 1.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 1.5 GO:0071253 connexin binding(GO:0071253)
0.3 2.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 3.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.4 GO:0031402 sodium ion binding(GO:0031402)
0.1 1.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.1 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.2 GO:0016015 morphogen activity(GO:0016015)
0.1 3.4 GO:0005179 hormone activity(GO:0005179)
0.0 1.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)