Motif ID: Foxd1

Z-value: 1.581


Transcription factors associated with Foxd1:

Gene SymbolEntrez IDGene Name
Foxd1 ENSMUSG00000078302.3 Foxd1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxd1mm10_v2_chr13_+_98354234_98354250-0.565.9e-07Click!


Activity profile for motif Foxd1.

activity profile for motif Foxd1


Sorted Z-values histogram for motif Foxd1

Sorted Z-values for motif Foxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144892813 22.565 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr8_-_84773381 20.813 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr4_+_144893077 18.265 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_144893127 16.137 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr18_+_69344503 15.942 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr13_-_93499803 14.082 ENSMUST00000065537.7
 Jmy
junction-mediating and regulatory protein
chr11_+_3332426 13.444 ENSMUST00000136474.1
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr8_+_65618009 12.062 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
 March1


membrane-associated ring finger (C3HC4) 1


chr12_-_100725028 11.345 ENSMUST00000043599.6
 Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr18_-_43059418 10.871 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr10_-_8518801 10.787 ENSMUST00000061601.7
 Ust
uronyl-2-sulfotransferase
chr16_-_74411292 10.397 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr16_-_4880284 10.145 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr11_+_3330781 9.778 ENSMUST00000136536.1
ENSMUST00000093399.4
 Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr10_+_29211637 9.654 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr14_-_18239053 9.570 ENSMUST00000090543.5
 Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr11_+_3330401 9.462 ENSMUST00000045153.4
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr7_+_126776939 9.171 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr5_+_3928033 7.848 ENSMUST00000143365.1
 Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr19_+_23141183 7.662 ENSMUST00000036884.1
 Klf9
Kruppel-like factor 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.2 57.0 GO:0042572 retinol metabolic process(GO:0042572)
4.7 32.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.5 20.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.6 15.9 GO:0042118 endothelial cell activation(GO:0042118)
0.8 14.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
3.5 14.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.8 12.5 GO:0045792 negative regulation of cell size(GO:0045792)
4.0 12.1 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.6 12.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
3.8 11.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
3.7 11.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
1.6 10.9 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
3.5 10.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 9.6 GO:2000505 regulation of energy homeostasis(GO:2000505)
1.8 9.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.8 8.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.7 8.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 8.0 GO:0030010 establishment of cell polarity(GO:0030010)
1.5 7.7 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.2 7.6 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 63.6 GO:0016021 integral component of membrane(GO:0016021)
0.1 28.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 16.0 GO:0000790 nuclear chromatin(GO:0000790)
0.4 14.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
3.6 14.2 GO:0044307 dendritic branch(GO:0044307)
0.0 13.0 GO:0031252 cell leading edge(GO:0031252)
0.7 12.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.1 12.5 GO:0031931 TORC1 complex(GO:0031931)
4.0 12.1 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.4 12.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 11.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 10.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 10.4 GO:0030673 axolemma(GO:0030673)
0.2 10.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 9.9 GO:0016607 nuclear speck(GO:0016607)
0.6 8.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 8.7 GO:0005769 early endosome(GO:0005769)
0.3 6.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 6.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 6.6 GO:0097060 synaptic membrane(GO:0097060)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.1 57.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
10.9 32.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.9 19.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
4.0 15.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 14.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 13.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
2.2 13.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
2.4 12.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
1.2 11.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 11.7 GO:0003713 transcription coactivator activity(GO:0003713)
3.8 11.3 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.8 10.9 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
1.2 10.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 8.9 GO:0042287 MHC protein binding(GO:0042287)
0.4 8.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 7.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 7.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 7.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
1.1 6.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.3 6.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)