Motif ID: Foxd3

Z-value: 0.514


Transcription factors associated with Foxd3:

Gene SymbolEntrez IDGene Name
Foxd3 ENSMUSG00000067261.3 Foxd3



Activity profile for motif Foxd3.

activity profile for motif Foxd3


Sorted Z-values histogram for motif Foxd3

Sorted Z-values for motif Foxd3



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_93199348 2.712 ENSMUST00000064775.6
Adcyap1
adenylate cyclase activating polypeptide 1
chr3_+_102010138 2.525 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr17_+_29090969 2.399 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr14_-_70630149 2.250 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr5_+_148265202 2.175 ENSMUST00000110515.2
Mtus2
microtubule associated tumor suppressor candidate 2
chr5_+_148265307 1.817 ENSMUST00000110514.1
Mtus2
microtubule associated tumor suppressor candidate 2
chr5_+_148265265 1.802 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr4_-_36056726 1.793 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr1_+_6734827 1.600 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr6_-_144209471 1.507 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr6_-_144209558 1.416 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr8_-_87959560 1.352 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr11_+_98798653 1.296 ENSMUST00000037930.6
Msl1
male-specific lethal 1 homolog (Drosophila)
chr12_+_111971545 1.231 ENSMUST00000079009.5
Tdrd9
tudor domain containing 9
chr16_+_13986596 1.227 ENSMUST00000056521.5
ENSMUST00000118412.1
ENSMUST00000131608.1
2900011O08Rik


RIKEN cDNA 2900011O08 gene


chr17_+_28691419 1.172 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr10_-_11080956 1.164 ENSMUST00000105560.1
Grm1
glutamate receptor, metabotropic 1
chr6_-_3494587 1.131 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr1_-_126830786 1.118 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr6_+_77242715 1.101 ENSMUST00000161677.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr1_-_126830632 1.092 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr6_+_77242644 1.081 ENSMUST00000159616.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr14_-_93888732 0.915 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr2_-_120539852 0.910 ENSMUST00000171215.1
Zfp106
zinc finger protein 106
chr5_-_88675190 0.878 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr2_+_9882622 0.806 ENSMUST00000114919.1
4930412O13Rik
RIKEN cDNA 4930412O13 gene
chr6_+_38918969 0.757 ENSMUST00000003017.6
Tbxas1
thromboxane A synthase 1, platelet
chr11_+_83302817 0.746 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr9_+_54980880 0.734 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chrX_+_164373363 0.714 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr15_+_100154379 0.668 ENSMUST00000023768.6
ENSMUST00000108971.2
Dip2b

DIP2 disco-interacting protein 2 homolog B (Drosophila)

chrX_-_163761323 0.660 ENSMUST00000059320.2
Rnf138rt1
ring finger protein 138, retrogene 1
chr2_+_152669461 0.655 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
H13



histocompatibility 13



chr17_+_28691342 0.598 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
Mapk14



mitogen-activated protein kinase 14



chr10_-_19011948 0.582 ENSMUST00000105527.1
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr10_-_127030789 0.578 ENSMUST00000120547.1
ENSMUST00000152054.1
Tsfm

Ts translation elongation factor, mitochondrial

chr11_-_107189325 0.534 ENSMUST00000018577.7
ENSMUST00000106757.1
Nol11

nucleolar protein 11

chr13_+_16014457 0.532 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr2_+_125136692 0.532 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr14_-_52213379 0.523 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr9_+_105642957 0.510 ENSMUST00000065778.6
Pik3r4
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
chr10_-_127030813 0.500 ENSMUST00000040560.4
Tsfm
Ts translation elongation factor, mitochondrial
chr1_+_134415414 0.474 ENSMUST00000112237.1
Adipor1
adiponectin receptor 1
chr10_+_11609256 0.463 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr13_-_18031616 0.353 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr5_-_120612558 0.342 ENSMUST00000140554.1
ENSMUST00000031599.2
ENSMUST00000177800.1
1110008J03Rik


RIKEN cDNA 1110008J03 gene


chr9_-_20879718 0.279 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr3_+_106034661 0.268 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr2_+_181767040 0.259 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr4_+_108847827 0.235 ENSMUST00000102738.2
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr19_+_8953826 0.215 ENSMUST00000096239.5
Tut1
terminal uridylyl transferase 1, U6 snRNA-specific
chr9_+_36832684 0.181 ENSMUST00000034630.8
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr2_+_181767283 0.175 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr18_+_37513652 0.127 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr5_-_31295862 0.111 ENSMUST00000041266.7
ENSMUST00000172435.1
Fndc4

fibronectin type III domain containing 4

chr19_-_8713862 0.105 ENSMUST00000010239.4
Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr2_-_160619971 0.063 ENSMUST00000109473.1
Gm14221
predicted gene 14221

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
0.7 2.2 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.4 1.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.4 2.9 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 2.4 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.2 0.7 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 1.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 1.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 1.2 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.2 0.6 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 0.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.5 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 2.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 1.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 2.5 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.5 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 1.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.5 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 1.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 1.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.7 GO:0035904 aorta development(GO:0035904)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 2.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 1.3 GO:0072487 MSL complex(GO:0072487)
0.2 0.5 GO:0034455 t-UTP complex(GO:0034455)
0.2 0.5 GO:0043512 inhibin A complex(GO:0043512)
0.2 1.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2 1.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1 0.7 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 5.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.7 GO:0043195 terminal bouton(GO:0043195)
0.0 2.9 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.8 GO:0000922 spindle pole(GO:0000922)
0.0 3.1 GO:0030426 growth cone(GO:0030426)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.1 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0051525 NFAT protein binding(GO:0051525)
0.3 1.2 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)
0.2 2.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 2.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.9 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.5 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.7 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 2.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 2.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 2.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 5.8 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.8 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.7 GO:0030276 clathrin binding(GO:0030276)