Motif ID: Foxg1

Z-value: 0.426


Transcription factors associated with Foxg1:

Gene SymbolEntrez IDGene Name
Foxg1 ENSMUSG00000020950.9 Foxg1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxg1mm10_v2_chr12_+_49382791_49382883-0.717.0e-12Click!


Activity profile for motif Foxg1.

activity profile for motif Foxg1


Sorted Z-values histogram for motif Foxg1

Sorted Z-values for motif Foxg1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxg1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_120476469 12.071 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr4_+_154960915 6.902 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr10_+_22158566 4.047 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr1_-_72874877 3.621 ENSMUST00000027377.8
 Igfbp5
insulin-like growth factor binding protein 5
chr12_-_10900296 3.383 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr13_-_3918157 2.640 ENSMUST00000091853.4
 Net1
neuroepithelial cell transforming gene 1
chr9_+_91378636 2.563 ENSMUST00000066384.5
 Zic4
zinc finger protein of the cerebellum 4
chr7_-_115824699 2.557 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr18_-_34007206 2.511 ENSMUST00000025234.5
 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr13_-_71963713 2.045 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr2_-_57124003 1.523 ENSMUST00000112629.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr11_-_89538556 1.343 ENSMUST00000169201.1
 Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr11_+_3488275 1.142 ENSMUST00000064265.6
 Pla2g3
phospholipase A2, group III
chr9_+_64121501 1.075 ENSMUST00000118215.1
 Lctl
lactase-like
chr1_-_84284423 1.066 ENSMUST00000176720.1
 Pid1
phosphotyrosine interaction domain containing 1
chr4_-_108833544 0.878 ENSMUST00000102740.1
ENSMUST00000102741.1
 Btf3l4

basic transcription factor 3-like 4

chr15_-_85581809 0.822 ENSMUST00000023015.7
 Wnt7b
wingless-related MMTV integration site 7B
chr18_+_73859366 0.766 ENSMUST00000120033.1
ENSMUST00000179472.1
ENSMUST00000119239.1
 Mro


maestro


chr3_-_95015214 0.724 ENSMUST00000128438.1
ENSMUST00000149747.1
ENSMUST00000019482.1
 Zfp687


zinc finger protein 687


chr13_+_34162953 0.722 ENSMUST00000124996.1
ENSMUST00000147632.1
 Psmg4

proteasome (prosome, macropain) assembly chaperone 4

chr10_-_24836165 0.708 ENSMUST00000020169.7
 Enpp3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr2_-_164389095 0.668 ENSMUST00000167427.1
 Slpi
secretory leukocyte peptidase inhibitor
chr5_-_134314678 0.635 ENSMUST00000174354.1
ENSMUST00000174155.1
ENSMUST00000174513.1
ENSMUST00000174772.1
ENSMUST00000173341.1
ENSMUST00000111261.4
ENSMUST00000082057.3
ENSMUST00000059042.7
 Gtf2i







general transcription factor II I







chr6_-_72345144 0.626 ENSMUST00000070345.3
 Usp39
ubiquitin specific peptidase 39
chr11_-_28583995 0.619 ENSMUST00000146385.2
 Ccdc85a
coiled-coil domain containing 85A
chr3_-_95015416 0.581 ENSMUST00000132195.1
 Zfp687
zinc finger protein 687
chr5_+_34369909 0.560 ENSMUST00000180376.1
 Fam193a
family with sequence similarity 193, member A
chr16_-_90284412 0.546 ENSMUST00000039280.7
 Scaf4
SR-related CTD-associated factor 4
chr2_+_174330006 0.543 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
 Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr16_-_90284300 0.522 ENSMUST00000163419.1
 Scaf4
SR-related CTD-associated factor 4
chr6_-_129717132 0.511 ENSMUST00000088046.1
 Klri1
killer cell lectin-like receptor family I member 1
chr12_-_104751900 0.498 ENSMUST00000041987.6
 Dicer1
dicer 1, ribonuclease type III
chr19_+_11770415 0.391 ENSMUST00000167199.1
 Mrpl16
mitochondrial ribosomal protein L16
chr14_-_24245913 0.380 ENSMUST00000073687.6
ENSMUST00000090398.4
 Dlg5

discs, large homolog 5 (Drosophila)

chr16_-_28929658 0.230 ENSMUST00000100023.1
 Mb21d2
Mab-21 domain containing 2
chr11_+_72607221 0.208 ENSMUST00000021148.6
ENSMUST00000138247.1
 Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr1_-_180813534 0.197 ENSMUST00000159789.1
ENSMUST00000081026.4
 H3f3a

H3 histone, family 3A

chr5_-_121191365 0.194 ENSMUST00000100770.2
ENSMUST00000054547.7
 Ptpn11

protein tyrosine phosphatase, non-receptor type 11

chr4_-_108833608 0.163 ENSMUST00000102742.4
 Btf3l4
basic transcription factor 3-like 4
chr1_-_180813591 0.147 ENSMUST00000162118.1
ENSMUST00000159685.1
ENSMUST00000161308.1
 H3f3a


H3 histone, family 3A


chr18_+_11839220 0.128 ENSMUST00000171109.1
ENSMUST00000046948.8
 Cables1

CDK5 and Abl enzyme substrate 1

chr9_-_60649793 0.093 ENSMUST00000053171.7
 Lrrc49
leucine rich repeat containing 49
chr9_+_106170918 0.074 ENSMUST00000020490.5
 Wdr82
WD repeat domain containing 82
chr6_-_12109583 0.016 ENSMUST00000080891.5
 Gm6578
predicted gene 6578
chr5_+_145204523 0.004 ENSMUST00000085671.3
ENSMUST00000031601.7
 Zkscan5

zinc finger with KRAB and SCAN domains 5

chr5_-_142906702 0.001 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
 Actb


actin, beta



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
1.3 12.1 GO:0060613 fat pad development(GO:0060613)
0.5 3.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4 1.5 GO:0051866 general adaptation syndrome(GO:0051866)
0.4 1.1 GO:0090298 positive regulation of fat cell proliferation(GO:0070346) negative regulation of mitochondrial DNA replication(GO:0090298)
0.3 1.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.3 0.8 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.2 2.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 0.5 GO:0071335 hair follicle cell proliferation(GO:0071335)
0.2 2.6 GO:0051451 myoblast migration(GO:0051451)
0.2 4.0 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 1.3 GO:0050957 equilibrioception(GO:0050957)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.2 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.7 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.7 GO:0019731 antibacterial humoral response(GO:0019731)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.9 3.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 12.1 GO:0000785 chromatin(GO:0000785)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 12.1 GO:0003680 AT DNA binding(GO:0003680)
0.5 4.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.5 3.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.8 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 0.7 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 2.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 1.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 5.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)