Motif ID: Foxo6

Z-value: 0.643


Transcription factors associated with Foxo6:

Gene SymbolEntrez IDGene Name
Foxo6 ENSMUSG00000052135.8 Foxo6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxo6mm10_v2_chr4_-_120287349_120287349-0.801.9e-16Click!


Activity profile for motif Foxo6.

activity profile for motif Foxo6


Sorted Z-values histogram for motif Foxo6

Sorted Z-values for motif Foxo6



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxo6

PNG image of the network

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Top targets:


Showing 1 to 20 of 74 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_12027958 8.970 ENSMUST00000109654.1
 Grb10
growth factor receptor bound protein 10
chr4_+_134510999 7.339 ENSMUST00000105866.2
 Aunip
aurora kinase A and ninein interacting protein
chr5_+_110330697 6.523 ENSMUST00000112481.1
 Pole
polymerase (DNA directed), epsilon
chr10_-_93310963 6.039 ENSMUST00000151153.1
 Elk3
ELK3, member of ETS oncogene family
chr1_+_74391479 5.747 ENSMUST00000027367.7
 Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr6_-_23248264 5.723 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr17_-_31277327 5.561 ENSMUST00000024832.7
 Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr10_-_93311073 5.165 ENSMUST00000008542.5
 Elk3
ELK3, member of ETS oncogene family
chr14_-_47418407 4.925 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr2_-_84425258 4.860 ENSMUST00000074262.2
 Calcrl
calcitonin receptor-like
chrX_+_106920618 4.214 ENSMUST00000060576.7
 Lpar4
lysophosphatidic acid receptor 4
chr15_+_3270767 4.163 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr19_-_45742873 3.926 ENSMUST00000026241.5
ENSMUST00000026240.7
ENSMUST00000111928.1
 Fgf8


fibroblast growth factor 8


chr5_+_7179299 3.471 ENSMUST00000179460.1
 Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr12_-_91384403 3.401 ENSMUST00000141429.1
 Cep128
centrosomal protein 128
chr13_-_71963713 3.396 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr1_+_51987139 3.300 ENSMUST00000168302.1
 Stat4
signal transducer and activator of transcription 4
chr11_-_89639631 3.150 ENSMUST00000128717.1
 Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr5_-_99037035 2.899 ENSMUST00000031277.6
 Prkg2
protein kinase, cGMP-dependent, type II
chr5_-_117389029 2.894 ENSMUST00000111953.1
ENSMUST00000086461.6
 Rfc5

replication factor C (activator 1) 5


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.2 GO:0042060 wound healing(GO:0042060)
0.1 9.6 GO:0007051 spindle organization(GO:0007051)
1.0 9.0 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
1.1 6.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
1.0 5.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 5.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 5.6 GO:0035082 axoneme assembly(GO:0035082)
1.2 4.9 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.6 4.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 4.1 GO:0006910 phagocytosis, recognition(GO:0006910)
1.3 3.9 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.3 3.1 GO:0050957 equilibrioception(GO:0050957)
0.4 2.9 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3 2.9 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.3 2.8 GO:0097421 liver regeneration(GO:0097421)
0.0 2.7 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.8 2.5 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.3 2.4 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 2.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.8 2.3 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.7 GO:0000922 spindle pole(GO:0000922)
1.3 6.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 5.6 GO:0001520 outer dense fiber(GO:0001520)
0.1 5.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 5.0 GO:0005923 bicellular tight junction(GO:0005923)
0.3 4.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 4.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.5 2.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 2.4 GO:0045120 pronucleus(GO:0045120)
0.2 2.3 GO:0097431 mitotic spindle pole(GO:0097431) mitotic spindle midzone(GO:1990023)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.0 1.4 GO:0001772 immunological synapse(GO:0001772)
0.4 1.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.9 GO:0097228 sperm midpiece(GO:0097225) sperm principal piece(GO:0097228)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 11.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 10.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.4 9.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.6 5.7 GO:0008420 CTD phosphatase activity(GO:0008420)
1.2 4.9 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 4.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.7 4.2 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.3 4.2 GO:0008430 selenium binding(GO:0008430)
0.2 4.1 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 4.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.3 3.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.7 2.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.3 2.9 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.7 2.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 2.4 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 2.4 GO:0019843 rRNA binding(GO:0019843)
0.1 2.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 2.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.5 1.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.4 1.4 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)