Motif ID: Foxp1_Foxj2

Z-value: 1.430

Transcription factors associated with Foxp1_Foxj2:

Gene SymbolEntrez IDGene Name
Foxj2 ENSMUSG00000003154.9 Foxj2
Foxp1 ENSMUSG00000030067.11 Foxp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj2mm10_v2_chr6_+_122819888_1228199380.908.9e-26Click!
Foxp1mm10_v2_chr6_-_99266494_992665400.573.0e-07Click!


Activity profile for motif Foxp1_Foxj2.

activity profile for motif Foxp1_Foxj2


Sorted Z-values histogram for motif Foxp1_Foxj2

Sorted Z-values for motif Foxp1_Foxj2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp1_Foxj2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 42.318 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr8_+_66386292 21.392 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr2_+_136713444 20.422 ENSMUST00000028727.4
ENSMUST00000110098.3
 Snap25

synaptosomal-associated protein 25

chr19_-_34255325 16.851 ENSMUST00000039631.8
 Acta2
actin, alpha 2, smooth muscle, aorta
chr6_-_148444336 16.728 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr9_-_121495678 15.227 ENSMUST00000035120.4
 Cck
cholecystokinin
chr16_-_4880284 14.674 ENSMUST00000037843.6
 Ubald1
UBA-like domain containing 1
chr7_+_16310412 14.342 ENSMUST00000136781.1
 Bbc3
BCL2 binding component 3
chr4_-_151108244 14.183 ENSMUST00000131948.1
 Camta1
calmodulin binding transcription activator 1
chr15_-_66969616 14.154 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr1_+_66386968 13.942 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr15_-_58214882 13.185 ENSMUST00000022986.6
 Fbxo32
F-box protein 32
chr18_+_36952621 13.101 ENSMUST00000115661.2
 Pcdha2
protocadherin alpha 2
chr18_+_69344503 12.871 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr4_-_87806296 12.693 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr4_+_155734800 12.314 ENSMUST00000147721.1
ENSMUST00000127188.2
 Tmem240

transmembrane protein 240

chr4_+_101507947 12.217 ENSMUST00000149047.1
ENSMUST00000106929.3
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr6_-_58907120 12.189 ENSMUST00000059539.3
 Nap1l5
nucleosome assembly protein 1-like 5
chr2_+_68117713 12.078 ENSMUST00000112346.2
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr10_+_60106452 11.502 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 392 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.8 39.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6 26.4 GO:0006376 mRNA splice site selection(GO:0006376)
1.2 26.3 GO:0016082 synaptic vesicle priming(GO:0016082)
1.4 26.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
1.9 24.1 GO:0070842 aggresome assembly(GO:0070842)
3.9 23.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 22.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.0 21.8 GO:0048268 clathrin coat assembly(GO:0048268)
1.3 21.6 GO:0045792 negative regulation of cell size(GO:0045792)
2.1 21.4 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.3 21.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.6 21.1 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.7 20.9 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
6.9 20.6 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
1.7 18.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) regulation of membrane depolarization during action potential(GO:0098902) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
4.6 18.5 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.8 18.4 GO:0007379 segment specification(GO:0007379)
1.8 18.2 GO:0042118 endothelial cell activation(GO:0042118)
0.7 17.3 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.2 17.1 GO:0001578 microtubule bundle formation(GO:0001578)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 159 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 99.4 GO:0060076 excitatory synapse(GO:0060076)
0.1 47.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
1.2 33.8 GO:0043194 axon initial segment(GO:0043194)
1.0 31.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 26.7 GO:0045202 synapse(GO:0045202)
0.1 26.4 GO:0030425 dendrite(GO:0030425)
0.1 21.4 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
5.1 20.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.9 20.4 GO:0031931 TORC1 complex(GO:0031931)
0.3 20.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.6 19.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.6 19.4 GO:0035861 site of double-strand break(GO:0035861)
0.1 19.4 GO:0097060 synaptic membrane(GO:0097060)
0.3 18.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 17.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.4 17.6 GO:0031941 filamentous actin(GO:0031941)
0.4 17.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 15.7 GO:0000139 Golgi membrane(GO:0000139)
1.5 13.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
2.8 13.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 267 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 53.1 GO:0017124 SH3 domain binding(GO:0017124)
1.5 36.2 GO:0017075 syntaxin-1 binding(GO:0017075)
1.0 30.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 28.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
1.3 26.2 GO:0042287 MHC protein binding(GO:0042287)
0.6 20.6 GO:0045296 cadherin binding(GO:0045296)
3.4 20.4 GO:0032051 clathrin light chain binding(GO:0032051)
2.0 20.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 19.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.8 17.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 17.0 GO:0051117 ATPase binding(GO:0051117)
4.2 16.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 14.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
4.8 14.3 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.0 14.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.7 13.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
2.1 12.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
2.1 12.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.5 12.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.6 11.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)