Motif ID: Gata2_Gata1
Z-value: 1.215
Transcription factors associated with Gata2_Gata1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Gata1 | ENSMUSG00000031162.8 | Gata1 |
| Gata2 | ENSMUSG00000015053.8 | Gata2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Gata2 | mm10_v2_chr6_+_88198656_88198675 | 0.79 | 5.9e-16 | Click! |
| Gata1 | mm10_v2_chrX_-_7967817_7967910 | 0.78 | 2.7e-15 | Click! |
Top targets:
Showing 1 to 20 of 154 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 75 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 15.8 | 79.0 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.3 | 33.3 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 2.4 | 23.5 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 3.6 | 21.5 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
| 7.1 | 21.4 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
| 2.0 | 19.7 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.3 | 18.5 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
| 5.2 | 15.6 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913) |
| 2.5 | 14.9 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 1.0 | 14.1 | GO:0034377 | plasma lipoprotein particle assembly(GO:0034377) |
| 1.5 | 13.4 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 1.9 | 13.2 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 1.8 | 12.6 | GO:0060586 | multicellular organismal iron ion homeostasis(GO:0060586) |
| 0.8 | 11.6 | GO:0046697 | decidualization(GO:0046697) |
| 2.3 | 11.3 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.5 | 10.9 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.5 | 10.8 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 1.1 | 10.6 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 1.0 | 10.3 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
| 3.3 | 9.9 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 43 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.9 | 79.0 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 1.8 | 29.0 | GO:0005614 | interstitial matrix(GO:0005614) |
| 4.3 | 21.5 | GO:0005861 | troponin complex(GO:0005861) |
| 3.1 | 18.5 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.0 | 17.3 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.1 | 15.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 13.6 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.7 | 11.7 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.2 | 11.3 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 11.3 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 1.0 | 9.9 | GO:0098533 | ATPase dependent transmembrane transport complex(GO:0098533) |
| 0.0 | 9.8 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 9.6 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.1 | 9.1 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.3 | 8.6 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.3 | 7.7 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.5 | 6.7 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.5 | 5.7 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.0 | 5.3 | GO:0005694 | chromosome(GO:0005694) |
| 0.3 | 5.0 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 68 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 15.8 | 79.0 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.0 | 38.7 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 1.2 | 32.8 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.9 | 23.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 7.2 | 21.5 | GO:0030172 | troponin C binding(GO:0030172) |
| 1.0 | 21.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 16.2 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.4 | 15.6 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 4.5 | 13.4 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 12.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.9 | 11.3 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 10.9 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 2.1 | 10.6 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 1.7 | 10.3 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 3.3 | 9.8 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.6 | 9.8 | GO:0016594 | glycine binding(GO:0016594) |
| 0.8 | 9.3 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 2.3 | 9.0 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
| 0.9 | 8.8 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.2 | 8.8 | GO:0001540 | beta-amyloid binding(GO:0001540) |
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