Motif ID: Gata4

Z-value: 0.689


Transcription factors associated with Gata4:

Gene SymbolEntrez IDGene Name
Gata4 ENSMUSG00000021944.9 Gata4



Activity profile for motif Gata4.

activity profile for motif Gata4


Sorted Z-values histogram for motif Gata4

Sorted Z-values for motif Gata4



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata4

PNG image of the network

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Top targets:


Showing 1 to 20 of 149 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_13751297 7.339 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_102010138 5.936 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr1_+_45311538 5.070 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr1_-_56969864 4.982 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr1_-_56969827 4.726 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr6_+_103510874 3.968 ENSMUST00000066905.6
 Chl1
cell adhesion molecule with homology to L1CAM
chr1_+_177444653 3.952 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr11_+_32276400 3.857 ENSMUST00000020531.2
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr10_-_62342674 3.758 ENSMUST00000143179.1
ENSMUST00000130422.1
 Hk1

hexokinase 1

chr11_+_32276893 3.528 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr16_-_34263179 3.505 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr16_-_34262830 3.358 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr2_+_65845833 3.307 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr1_-_132367879 3.173 ENSMUST00000142609.1
 Tmcc2
transmembrane and coiled-coil domains 2
chr6_-_55681257 3.037 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr2_-_52558539 3.013 ENSMUST00000102760.3
ENSMUST00000102761.2
 Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr5_-_73191848 2.910 ENSMUST00000176910.1
 Fryl
furry homolog-like (Drosophila)
chr4_-_87806276 2.890 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_+_4559742 2.881 ENSMUST00000176828.1
 Frmd4a
FERM domain containing 4A
chr18_+_36952621 2.874 ENSMUST00000115661.2
 Pcdha2
protocadherin alpha 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 12.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.2 9.7 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.6 9.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.5 7.4 GO:0015671 oxygen transport(GO:0015671)
0.1 7.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 6.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 5.9 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.6 5.8 GO:0007379 segment specification(GO:0007379)
0.1 5.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
1.0 5.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 4.4 GO:0001541 ovarian follicle development(GO:0001541)
0.1 4.0 GO:0035640 exploration behavior(GO:0035640)
0.1 4.0 GO:0021766 hippocampus development(GO:0021766)
0.8 3.8 GO:0010359 regulation of anion channel activity(GO:0010359)
0.2 3.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 3.6 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 3.6 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.2 3.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.4 3.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2 3.0 GO:0021542 dentate gyrus development(GO:0021542)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 16.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.9 7.4 GO:0005833 hemoglobin complex(GO:0005833)
0.1 7.1 GO:0016363 nuclear matrix(GO:0016363)
0.1 5.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 5.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.4 5.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 4.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 4.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 3.8 GO:0097228 sperm principal piece(GO:0097228)
0.1 3.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.2 GO:0016605 PML body(GO:0016605)
0.2 2.6 GO:0031143 pseudopodium(GO:0031143)
0.2 2.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.5 GO:0030427 site of polarized growth(GO:0030427)
0.5 2.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.4 2.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 2.2 GO:0030425 dendrite(GO:0030425)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 15.4 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 11.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 10.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 8.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
1.5 7.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 5.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.3 5.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 4.8 GO:0002020 protease binding(GO:0002020)
0.9 4.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 4.4 GO:0017124 SH3 domain binding(GO:0017124)
0.8 3.8 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 3.7 GO:0005096 GTPase activator activity(GO:0005096)
0.4 3.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 3.6 GO:0008565 protein transporter activity(GO:0008565)
0.1 3.3 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 2.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 2.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.3 GO:0016594 glycine binding(GO:0016594)
0.1 2.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 2.1 GO:0050733 RS domain binding(GO:0050733)