Motif ID: Gata6

Z-value: 0.323


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103853199 1.746 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr6_-_23248264 1.537 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr10_-_86732409 1.529 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr11_+_67586675 1.279 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr2_+_65930117 1.239 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr4_+_13751297 1.222 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_86078070 1.131 ENSMUST00000032069.5
Add2
adducin 2 (beta)
chr1_+_45311538 0.937 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr10_-_62342674 0.895 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr8_+_45628176 0.891 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627709 0.862 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr9_+_66350465 0.849 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr19_+_4711153 0.836 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr6_+_58833689 0.831 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr3_-_154330543 0.816 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr11_+_4883186 0.797 ENSMUST00000139737.1
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr2_+_68104671 0.783 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr6_+_58831748 0.717 ENSMUST00000126292.1
ENSMUST00000031823.5
Herc3

hect domain and RLD 3

chr1_+_152954966 0.701 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr16_-_34262945 0.686 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr8_+_45627946 0.682 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr11_-_102365111 0.643 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr5_+_76840597 0.588 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik


RIKEN cDNA C530008M17 gene


chr5_-_73191848 0.575 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr4_-_46404224 0.544 ENSMUST00000107764.2
Hemgn
hemogen
chr12_+_95692212 0.539 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr2_-_7396192 0.517 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr5_+_121777929 0.516 ENSMUST00000160821.1
Atxn2
ataxin 2
chr8_-_64205970 0.484 ENSMUST00000066166.4
Tll1
tolloid-like
chr2_+_80617045 0.425 ENSMUST00000028384.4
Dusp19
dual specificity phosphatase 19
chr7_+_119900099 0.419 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr2_-_7081207 0.400 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr16_-_46010212 0.398 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr6_-_38124568 0.388 ENSMUST00000040259.4
Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr2_-_7395879 0.384 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr8_-_122699066 0.380 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr17_+_34604819 0.367 ENSMUST00000173242.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr15_-_83170168 0.367 ENSMUST00000162834.1
Cyb5r3
cytochrome b5 reductase 3
chr6_-_127109517 0.361 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr9_-_29963112 0.359 ENSMUST00000075069.4
Ntm
neurotrimin
chr7_-_99238564 0.342 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr15_-_83170498 0.334 ENSMUST00000162178.1
Cyb5r3
cytochrome b5 reductase 3
chr5_-_30461902 0.284 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
Otof



otoferlin



chr2_-_59948155 0.280 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr11_+_4986824 0.277 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr2_-_7081256 0.276 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr17_-_33713372 0.274 ENSMUST00000173392.1
March2
membrane-associated ring finger (C3HC4) 2
chr2_-_33087169 0.217 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr9_-_65827544 0.211 ENSMUST00000159109.1
Zfp609
zinc finger protein 609
chr6_-_136875794 0.206 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr3_-_20242173 0.205 ENSMUST00000001921.1
Cpa3
carboxypeptidase A3, mast cell
chr10_+_53337686 0.200 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chr10_+_40883469 0.194 ENSMUST00000019975.7
Wasf1
WAS protein family, member 1
chr11_+_95712673 0.190 ENSMUST00000107717.1
Zfp652
zinc finger protein 652
chr1_+_179803376 0.187 ENSMUST00000097454.2
Gm10518
predicted gene 10518
chr2_+_143915273 0.185 ENSMUST00000103172.3
Dstn
destrin
chr6_-_7983424 0.184 ENSMUST00000178598.1
Gm9825
predicted gene 9825
chr1_-_173333503 0.164 ENSMUST00000038227.4
Darc
Duffy blood group, chemokine receptor
chr2_-_33086366 0.160 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr1_-_25829511 0.147 ENSMUST00000135518.1
ENSMUST00000151309.1
Bai3

brain-specific angiogenesis inhibitor 3

chr7_-_119895446 0.125 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr9_+_44379490 0.112 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr16_+_58670208 0.103 ENSMUST00000060077.5
Cpox
coproporphyrinogen oxidase
chr6_-_122609964 0.101 ENSMUST00000032211.4
Gdf3
growth differentiation factor 3
chr16_+_36041184 0.097 ENSMUST00000042203.8
Wdr5b
WD repeat domain 5B
chr17_+_71204647 0.091 ENSMUST00000126681.1
Lpin2
lipin 2
chr9_-_106887000 0.085 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr11_-_70220969 0.067 ENSMUST00000060010.2
Slc16a13
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr2_-_7395968 0.061 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2
chr11_-_103697898 0.059 ENSMUST00000021329.7
Gosr2
golgi SNAP receptor complex member 2
chr2_+_125859134 0.049 ENSMUST00000028636.6
ENSMUST00000125084.1
Galk2

galactokinase 2

chr10_+_52417532 0.030 ENSMUST00000023830.8
Nus1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
chr13_-_91388079 0.028 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chr2_+_172370658 0.024 ENSMUST00000151511.1
ENSMUST00000116375.1
Cstf1

cleavage stimulation factor, 3' pre-RNA, subunit 1

chr15_+_18818895 0.018 ENSMUST00000166873.2
Cdh10
cadherin 10
chr16_+_44943737 0.015 ENSMUST00000114622.3
ENSMUST00000166731.1
Cd200r3

CD200 receptor 3

chr11_+_87581041 0.011 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
Sept4


septin 4


chr10_-_34207551 0.011 ENSMUST00000048010.7
Dse
dermatan sulfate epimerase
chr11_-_53707269 0.005 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50

RAD50 homolog (S. cerevisiae)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0015671 oxygen transport(GO:0015671)
0.3 1.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.9 GO:0010359 regulation of anion channel activity(GO:0010359)
0.2 0.7 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.7 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 2.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 2.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 1.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0046339 glycerol metabolic process(GO:0006071) diacylglycerol metabolic process(GO:0046339)
0.0 0.6 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.0 0.2 GO:0033574 response to testosterone(GO:0033574) adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.8 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.0 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.8 GO:0008091 spectrin(GO:0008091)
0.1 1.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 0.9 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.7 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.8 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.0 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)