Motif ID: Gata6

Z-value: 0.323


Transcription factors associated with Gata6:

Gene SymbolEntrez IDGene Name
Gata6 ENSMUSG00000005836.8 Gata6



Activity profile for motif Gata6.

activity profile for motif Gata6


Sorted Z-values histogram for motif Gata6

Sorted Z-values for motif Gata6



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata6

PNG image of the network

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Top targets:


Showing 1 to 20 of 79 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 1.746 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr6_-_23248264 1.537 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr10_-_86732409 1.529 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr11_+_67586675 1.279 ENSMUST00000108680.1
 Gas7
growth arrest specific 7
chr2_+_65930117 1.239 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr4_+_13751297 1.222 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_86078070 1.131 ENSMUST00000032069.5
 Add2
adducin 2 (beta)
chr1_+_45311538 0.937 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr10_-_62342674 0.895 ENSMUST00000143179.1
ENSMUST00000130422.1
 Hk1

hexokinase 1

chr8_+_45628176 0.891 ENSMUST00000130850.1
 Sorbs2
sorbin and SH3 domain containing 2
chr8_+_45627709 0.862 ENSMUST00000134321.1
ENSMUST00000135336.1
 Sorbs2

sorbin and SH3 domain containing 2

chr9_+_66350465 0.849 ENSMUST00000042824.6
 Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr19_+_4711153 0.836 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr6_+_58833689 0.831 ENSMUST00000041401.8
 Herc3
hect domain and RLD 3
chr3_-_154330543 0.816 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr11_+_4883186 0.797 ENSMUST00000139737.1
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr2_+_68104671 0.783 ENSMUST00000042456.3
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr6_+_58831748 0.717 ENSMUST00000126292.1
ENSMUST00000031823.5
 Herc3

hect domain and RLD 3

chr1_+_152954966 0.701 ENSMUST00000043313.8
 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr16_-_34262945 0.686 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.3 1.7 GO:0015671 oxygen transport(GO:0015671)
0.0 1.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 1.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 1.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.9 GO:0010359 regulation of anion channel activity(GO:0010359)
0.1 0.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.8 GO:0021884 forebrain neuron development(GO:0021884)
0.2 0.7 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.7 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.6 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.7 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.8 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.7 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.2 0.9 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.8 GO:0042165 neurotransmitter binding(GO:0042165)
0.2 0.7 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.6 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.3 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)