Motif ID: Gli2

Z-value: 0.564


Transcription factors associated with Gli2:

Gene SymbolEntrez IDGene Name
Gli2 ENSMUSG00000048402.8 Gli2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli2mm10_v2_chr1_-_119053619_1190536380.123.4e-01Click!


Activity profile for motif Gli2.

activity profile for motif Gli2


Sorted Z-values histogram for motif Gli2

Sorted Z-values for motif Gli2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gli2

PNG image of the network

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Top targets:


Showing 1 to 20 of 140 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_56694525 2.787 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr12_+_58211772 2.658 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr6_-_23248264 2.650 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr6_-_72789240 1.948 ENSMUST00000069536.5
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr7_-_137314394 1.883 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr12_+_38780284 1.811 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chrX_-_9662950 1.732 ENSMUST00000033519.2
Dynlt3
dynein light chain Tctex-type 3
chr6_-_72788952 1.672 ENSMUST00000114053.2
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr7_-_4752972 1.533 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr18_+_86394952 1.485 ENSMUST00000058829.2
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr1_+_55406163 1.468 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr5_-_53213447 1.300 ENSMUST00000031090.6
Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr16_-_88056176 1.280 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
Grik1


glutamate receptor, ionotropic, kainate 1


chr8_+_127064022 1.254 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr8_+_127064107 1.221 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr10_+_93589413 1.215 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr4_+_36952930 1.170 ENSMUST00000144029.1
Gm12371
predicted gene 12371
chr8_+_127063893 1.109 ENSMUST00000162309.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr3_+_107036156 1.081 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr3_+_127633134 1.038 ENSMUST00000029587.7
Neurog2
neurogenin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 3.6 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.6 3.6 GO:0003383 apical constriction(GO:0003383)
0.7 2.8 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.4 2.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 2.7 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 2.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.6 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.3 1.5 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 1.5 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
0.2 1.4 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 1.3 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1 1.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 1.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.0 GO:0071435 potassium ion export(GO:0071435)
0.0 1.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.8 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.6 GO:0033269 internode region of axon(GO:0033269)
0.1 3.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.5 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.4 GO:0097470 ribbon synapse(GO:0097470)
0.2 1.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 0.6 GO:0090537 CERF complex(GO:0090537)
0.1 0.5 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 5.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 3.6 GO:0008013 beta-catenin binding(GO:0008013)
0.9 2.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.8 2.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 2.3 GO:0003774 motor activity(GO:0003774)
0.1 1.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 1.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 1.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 1.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 1.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 0.8 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)