Motif ID: Gmeb1

Z-value: 0.678


Transcription factors associated with Gmeb1:

Gene SymbolEntrez IDGene Name
Gmeb1 ENSMUSG00000028901.7 Gmeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb1mm10_v2_chr4_-_132261596_1322616220.405.8e-04Click!


Activity profile for motif Gmeb1.

activity profile for motif Gmeb1


Sorted Z-values histogram for motif Gmeb1

Sorted Z-values for motif Gmeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 74 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_113531675 8.564 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr1_+_175880775 8.184 ENSMUST00000039725.6
Exo1
exonuclease 1
chr7_-_19310035 7.585 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr2_-_157007039 7.486 ENSMUST00000103129.2
ENSMUST00000103130.1
Dsn1

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr3_+_40800054 6.879 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr15_+_99074968 6.819 ENSMUST00000039665.6
Troap
trophinin associated protein
chr2_-_157007015 6.801 ENSMUST00000146413.1
Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr8_-_94918012 6.489 ENSMUST00000077955.5
Ccdc102a
coiled-coil domain containing 102A
chr3_+_40800013 6.182 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr3_+_127553462 4.984 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr19_+_43612299 4.712 ENSMUST00000057178.9
Nkx2-3
NK2 homeobox 3
chr17_+_23679363 4.300 ENSMUST00000024699.2
Cldn6
claudin 6
chr11_-_100822525 4.292 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chrX_+_112311334 4.217 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr11_-_40733373 3.974 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr8_-_45333189 3.558 ENSMUST00000095328.4
Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
chr13_-_53473074 3.549 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr11_+_86544982 3.388 ENSMUST00000108030.2
ENSMUST00000020821.3
ENSMUST00000069503.6
ENSMUST00000167178.2
Tubd1



tubulin, delta 1



chr3_+_138143429 3.228 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr3_-_138143352 3.028 ENSMUST00000098580.2
Mttp
microsomal triglyceride transfer protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 13.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 9.9 GO:0007059 chromosome segregation(GO:0007059)
1.2 8.6 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.8 8.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 7.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.2 5.9 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.8 4.7 GO:0002317 plasma cell differentiation(GO:0002317)
1.4 4.3 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.0 4.3 GO:0045216 cell-cell junction organization(GO:0045216)
0.3 4.2 GO:0042407 cristae formation(GO:0042407)
0.0 4.2 GO:0007283 spermatogenesis(GO:0007283)
0.0 3.6 GO:0019395 fatty acid oxidation(GO:0019395)
1.2 3.5 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
1.1 3.3 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.6 3.0 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 2.9 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 2.9 GO:0051028 mRNA transport(GO:0051028)
0.0 2.6 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.8 2.4 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.3 2.4 GO:0061084 negative regulation of protein refolding(GO:0061084)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 14.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.6 13.1 GO:0098536 deuterosome(GO:0098536)
0.1 8.6 GO:0000793 condensed chromosome(GO:0000793)
0.1 6.5 GO:0016459 myosin complex(GO:0016459)
0.0 5.0 GO:0005667 transcription factor complex(GO:0005667)
0.2 4.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.5 4.2 GO:0061617 MICOS complex(GO:0061617)
0.2 3.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 3.3 GO:0005681 spliceosomal complex(GO:0005681)
0.2 3.0 GO:0031528 microvillus membrane(GO:0031528)
0.2 2.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.7 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 1.3 GO:0071942 XPC complex(GO:0071942)
0.1 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.6 9.4 GO:0070182 DNA polymerase binding(GO:0070182)
2.0 8.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 7.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 6.5 GO:0003774 motor activity(GO:0003774)
0.1 5.9 GO:0000049 tRNA binding(GO:0000049)
0.1 4.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 4.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 3.6 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.0 3.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.3 GO:0043236 laminin binding(GO:0043236)
0.1 3.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.7 2.9 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3 2.4 GO:0032564 dATP binding(GO:0032564)
0.0 2.1 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1 1.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 1.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 1.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)