Motif ID: Gmeb2

Z-value: 0.594


Transcription factors associated with Gmeb2:

Gene SymbolEntrez IDGene Name
Gmeb2 ENSMUSG00000038705.7 Gmeb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb2mm10_v2_chr2_-_181288016_1812880410.209.2e-02Click!


Activity profile for motif Gmeb2.

activity profile for motif Gmeb2


Sorted Z-values histogram for motif Gmeb2

Sorted Z-values for motif Gmeb2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_78544345 3.560 ENSMUST00000053239.2
Sstr3
somatostatin receptor 3
chr7_-_119896285 2.019 ENSMUST00000106519.1
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr7_+_66839726 1.732 ENSMUST00000098382.3
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr7_+_66839752 1.720 ENSMUST00000107478.1
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr1_+_185454803 1.689 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr12_+_102554966 1.372 ENSMUST00000021610.5
Chga
chromogranin A
chr7_-_119895697 1.325 ENSMUST00000059851.6
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr5_-_31291026 1.295 ENSMUST00000041565.7
Ift172
intraflagellar transport 172
chr1_-_77515048 1.240 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr3_-_89089955 1.122 ENSMUST00000166687.1
Rusc1
RUN and SH3 domain containing 1
chr6_-_39725193 1.114 ENSMUST00000101497.3
Braf
Braf transforming gene
chr12_+_73964481 1.017 ENSMUST00000021532.4
Snapc1
small nuclear RNA activating complex, polypeptide 1
chr7_+_119896292 0.914 ENSMUST00000106517.1
Lyrm1
LYR motif containing 1
chr17_-_94749874 0.911 ENSMUST00000171284.1
Mettl4
methyltransferase like 4
chr13_+_49653297 0.908 ENSMUST00000021824.7
Nol8
nucleolar protein 8
chr7_-_119895446 0.899 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr17_-_85090204 0.889 ENSMUST00000072406.3
ENSMUST00000171795.1
Prepl

prolyl endopeptidase-like

chr11_+_83302817 0.841 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr8_+_70754679 0.839 ENSMUST00000110093.2
ENSMUST00000143118.1
ENSMUST00000034301.5
ENSMUST00000110090.1
Rab3a



RAB3A, member RAS oncogene family



chr7_+_119895836 0.814 ENSMUST00000106518.1
ENSMUST00000054440.3
Lyrm1

LYR motif containing 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.2 GO:0010225 response to UV-C(GO:0010225)
0.1 4.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 1.7 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 1.5 GO:0035904 aorta development(GO:0035904)
0.5 1.4 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.2 1.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.3 GO:0070986 left/right axis specification(GO:0070986)
0.4 1.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.4 1.2 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.1 1.2 GO:0046033 AMP metabolic process(GO:0046033)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 1.1 GO:0045346 regulation of MHC class II biosynthetic process(GO:0045346)
0.3 1.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 1.0 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.3 0.8 GO:0050975 sensory perception of touch(GO:0050975)
0.2 0.7 GO:0042939 glutathione transport(GO:0034635) oligopeptide transmembrane transport(GO:0035672) xenobiotic transport(GO:0042908) tripeptide transport(GO:0042939)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.7 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 3.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 1.4 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.2 GO:0031901 early endosome membrane(GO:0031901)
0.2 1.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.1 0.6 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.1 0.3 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.2 GO:0097602 cullin family protein binding(GO:0097602)
1.2 3.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 2.7 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.8 GO:0030276 clathrin binding(GO:0030276)
0.0 1.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.4 1.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4 1.2 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.3 1.2 GO:0042731 PH domain binding(GO:0042731)
0.0 1.2 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.1 1.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 0.7 GO:0015562 efflux transmembrane transporter activity(GO:0015562) oligopeptide transmembrane transporter activity(GO:0035673)
0.2 0.7 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)