Motif ID: Gmeb2
Z-value: 0.594
Transcription factors associated with Gmeb2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Gmeb2 | ENSMUSG00000038705.7 | Gmeb2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Gmeb2 | mm10_v2_chr2_-_181288016_181288041 | 0.20 | 9.2e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.4 | GO:1900736 | regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) |
0.4 | 1.2 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
0.4 | 1.2 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
0.3 | 0.8 | GO:0050975 | sensory perception of touch(GO:0050975) |
0.3 | 1.0 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
0.2 | 0.7 | GO:0042939 | glutathione transport(GO:0034635) oligopeptide transmembrane transport(GO:0035672) xenobiotic transport(GO:0042908) tripeptide transport(GO:0042939) |
0.2 | 4.2 | GO:0010225 | response to UV-C(GO:0010225) |
0.2 | 1.0 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
0.2 | 1.7 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
0.2 | 1.4 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
0.2 | 0.5 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
0.2 | 1.1 | GO:0045346 | regulation of MHC class II biosynthetic process(GO:0045346) |
0.1 | 0.4 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.1 | 0.4 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.1 | 0.6 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
0.1 | 0.5 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
0.1 | 4.1 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.1 | 0.3 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
0.1 | 0.6 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
0.1 | 0.6 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.1 | 0.2 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
0.1 | 1.3 | GO:0070986 | left/right axis specification(GO:0070986) |
0.1 | 0.3 | GO:0018307 | enzyme active site formation(GO:0018307) |
0.1 | 0.2 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.1 | 0.3 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.1 | 0.7 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.1 | 0.7 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.1 | 0.3 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
0.1 | 0.4 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.1 | 0.2 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
0.1 | 0.3 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.1 | 0.3 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
0.1 | 0.3 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.1 | 1.2 | GO:0046033 | AMP metabolic process(GO:0046033) |
0.1 | 0.3 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.1 | 0.3 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.1 | 0.4 | GO:1903441 | protein localization to ciliary membrane(GO:1903441) |
0.0 | 0.6 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.0 | 0.5 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
0.0 | 0.5 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.0 | 1.2 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
0.0 | 0.5 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 0.5 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.0 | 0.1 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
0.0 | 0.3 | GO:0031053 | primary miRNA processing(GO:0031053) |
0.0 | 0.7 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
0.0 | 0.1 | GO:1900242 | regulation of synaptic vesicle endocytosis(GO:1900242) |
0.0 | 0.1 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.0 | 0.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.0 | 0.1 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
0.0 | 0.1 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.0 | 0.7 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 1.5 | GO:0035904 | aorta development(GO:0035904) |
0.0 | 1.2 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.1 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
0.0 | 0.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.2 | GO:0006337 | nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986) |
0.0 | 0.4 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.3 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
0.0 | 0.1 | GO:0030397 | membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081) |
0.0 | 0.4 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.3 | GO:0071549 | cellular response to dexamethasone stimulus(GO:0071549) |
0.0 | 0.1 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
0.0 | 0.4 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.0 | GO:0032511 | regulation of multivesicular body size(GO:0010796) late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.0 | 0.2 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.4 | GO:0042583 | chromaffin granule(GO:0042583) |
0.2 | 1.0 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.1 | 0.5 | GO:0032280 | symmetric synapse(GO:0032280) |
0.1 | 0.3 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.1 | 0.6 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
0.1 | 0.2 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.1 | 0.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.1 | 0.5 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
0.1 | 3.6 | GO:0060170 | ciliary membrane(GO:0060170) |
0.1 | 1.4 | GO:0097225 | sperm midpiece(GO:0097225) |
0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 0.4 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
0.0 | 1.5 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.3 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 0.2 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.2 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
0.0 | 0.2 | GO:0070187 | telosome(GO:0070187) |
0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 1.7 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.2 | GO:0060091 | kinocilium(GO:0060091) |
0.0 | 0.3 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.0 | 1.2 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.1 | GO:1990879 | CST complex(GO:1990879) |
0.0 | 0.4 | GO:0031045 | dense core granule(GO:0031045) |
0.0 | 0.6 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.2 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.0 | 0.3 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.0 | 0.6 | GO:0070382 | exocytic vesicle(GO:0070382) |
0.0 | 0.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.0 | 0.0 | GO:0000814 | ESCRT II complex(GO:0000814) |
0.0 | 4.7 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
0.0 | 0.6 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 0.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 0.3 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 0.2 | GO:0001741 | XY body(GO:0001741) |
0.0 | 0.7 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 0.1 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.0 | 0.3 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) |
0.0 | 0.1 | GO:0032156 | septin cytoskeleton(GO:0032156) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.6 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.4 | 1.2 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.4 | 1.2 | GO:0017084 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
0.3 | 1.2 | GO:0042731 | PH domain binding(GO:0042731) |
0.2 | 0.7 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) oligopeptide transmembrane transporter activity(GO:0035673) |
0.2 | 0.7 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.2 | 4.2 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.2 | 0.5 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
0.1 | 0.5 | GO:0036033 | mediator complex binding(GO:0036033) |
0.1 | 0.3 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
0.1 | 1.0 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.1 | 2.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.1 | 0.3 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.1 | 0.4 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.1 | 2.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 0.7 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.1 | 0.5 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.1 | 0.3 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
0.1 | 0.9 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
0.1 | 0.3 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.1 | 0.2 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.1 | 0.2 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.0 | 0.5 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.0 | 0.3 | GO:0031685 | adenosine receptor binding(GO:0031685) |
0.0 | 1.4 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.0 | 0.4 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.4 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.0 | 0.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.4 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.3 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.0 | 1.8 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 0.7 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 0.1 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
0.0 | 0.1 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.0 | 0.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 0.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.0 | 0.4 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.0 | 0.1 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
0.0 | 0.2 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
0.0 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.2 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.2 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.0 | 0.2 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 0.1 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
0.0 | 0.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.6 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.0 | 1.2 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
0.0 | 0.0 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
0.0 | 0.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.0 | GO:0019153 | protein-disulfide reductase (glutathione) activity(GO:0019153) |
0.0 | 0.5 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
0.0 | 0.7 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.0 | 0.4 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |