Motif ID: Gsx2_Hoxd3_Vax1

Z-value: 0.725

Transcription factors associated with Gsx2_Hoxd3_Vax1:

Gene SymbolEntrez IDGene Name
Gsx2 ENSMUSG00000035946.6 Gsx2
Hoxd3 ENSMUSG00000079277.3 Hoxd3
Vax1 ENSMUSG00000006270.6 Vax1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gsx2mm10_v2_chr5_+_75075464_750756010.782.0e-15Click!
Vax1mm10_v2_chr19_-_59170978_591709780.758.2e-14Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gsx2_Hoxd3_Vax1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_8710734 16.232 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 15.171 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_48662740 9.142 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_+_109917639 8.713 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr15_+_25773985 8.659 ENSMUST00000125667.1
Myo10
myosin X
chr18_+_56432116 7.397 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr8_+_94152607 7.156 ENSMUST00000034211.8
Mt3
metallothionein 3
chr2_-_168767136 6.945 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr2_-_168767029 5.824 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr9_+_119063429 5.681 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr2_+_91457501 5.495 ENSMUST00000028689.3
Lrp4
low density lipoprotein receptor-related protein 4
chr3_+_66219909 4.989 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr3_+_159839729 4.927 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr19_+_55895508 4.757 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr13_-_53473074 4.718 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr4_+_8690399 4.585 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr15_-_37459327 4.482 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr9_-_90255927 4.323 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr13_+_51408618 3.795 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr18_+_57142782 3.621 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr6_-_34317442 3.518 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr4_-_14621669 3.365 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr17_-_70853482 3.193 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr10_-_8886033 3.043 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr11_+_59306920 2.941 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr12_+_38780284 2.902 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr2_+_91257323 2.707 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr4_-_14621805 2.655 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr14_+_118854695 2.647 ENSMUST00000100314.3
Cldn10
claudin 10
chr5_+_138187485 2.360 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr2_+_71389239 2.357 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr4_-_14621494 2.120 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr13_-_102905740 2.119 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr2_+_120476911 2.118 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr13_-_102906046 2.100 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr15_+_98571004 2.046 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chrX_+_150547375 2.024 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chrX_-_101086020 2.015 ENSMUST00000113710.1
Slc7a3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr4_-_42661893 2.015 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr12_+_38781093 2.002 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr5_-_62765618 1.978 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_39006272 1.906 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr11_+_114851507 1.906 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr11_-_109611417 1.898 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
Wipi1


WD repeat domain, phosphoinositide interacting 1


chr6_-_23248264 1.861 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr12_+_38780817 1.828 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr12_-_55014329 1.752 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr14_+_79515618 1.727 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr3_-_59220150 1.699 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr2_-_28916412 1.588 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr1_+_161070767 1.545 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
Cenpl


centromere protein L


chr2_-_120154600 1.533 ENSMUST00000028755.7
Ehd4
EH-domain containing 4
chr10_+_128337761 1.471 ENSMUST00000005826.7
Cs
citrate synthase
chr14_+_26259109 1.424 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr12_-_79296266 1.423 ENSMUST00000021547.6
Zfyve26
zinc finger, FYVE domain containing 26
chr2_+_20737306 1.387 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr9_-_39603635 1.343 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chrX_+_106920618 1.262 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr14_+_26119811 1.211 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr14_+_25980039 1.145 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr1_-_163725123 1.125 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr6_+_63255971 1.103 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr7_+_101896340 1.096 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr5_-_62766153 1.092 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_-_28916668 1.087 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr2_+_19371636 1.086 ENSMUST00000023856.8
Msrb2
methionine sulfoxide reductase B2
chr5_-_138187177 0.995 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr14_+_47298260 0.971 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chr9_+_94669876 0.924 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr2_-_29787622 0.867 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr8_-_106573461 0.864 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr2_+_36230426 0.848 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr11_+_60537978 0.835 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr14_+_48446128 0.833 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr5_+_48242549 0.802 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chrX_-_160138375 0.800 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr5_-_149051300 0.799 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr3_+_53488677 0.798 ENSMUST00000029307.3
Stoml3
stomatin (Epb7.2)-like 3
chr5_-_63968867 0.756 ENSMUST00000154169.1
Rell1
RELT-like 1
chr2_-_164389095 0.743 ENSMUST00000167427.1
Slpi
secretory leukocyte peptidase inhibitor
chr4_-_117682233 0.717 ENSMUST00000102687.3
Dmap1
DNA methyltransferase 1-associated protein 1
chr6_+_8948608 0.684 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr12_-_80643799 0.676 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr1_-_152625212 0.674 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr9_+_121950988 0.660 ENSMUST00000043011.7
Fam198a
family with sequence similarity 198, member A
chr3_+_103739366 0.651 ENSMUST00000106852.1
Gm10964
predicted gene 10964
chr15_-_63997969 0.651 ENSMUST00000164532.1
Fam49b
family with sequence similarity 49, member B
chr10_-_83648631 0.649 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr2_-_91649751 0.642 ENSMUST00000099714.3
Zfp408
zinc finger protein 408
chr12_+_111814170 0.642 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr14_+_69347587 0.635 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr11_+_58171648 0.625 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr5_-_137072254 0.622 ENSMUST00000077523.3
ENSMUST00000041388.4
Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr10_+_128083273 0.612 ENSMUST00000026459.5
Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr2_+_110597298 0.592 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chrX_+_169685191 0.590 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr12_+_112760652 0.587 ENSMUST00000063888.3
Pld4
phospholipase D family, member 4
chr9_+_37208291 0.576 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr13_-_97747373 0.545 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr8_-_112011266 0.539 ENSMUST00000164470.1
ENSMUST00000093120.5
Kars

lysyl-tRNA synthetase

chr6_+_145934113 0.520 ENSMUST00000032383.7
Sspn
sarcospan
chr3_-_33082004 0.503 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr8_-_112011320 0.494 ENSMUST00000034426.6
Kars
lysyl-tRNA synthetase
chrX_+_9885622 0.489 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr6_-_54566484 0.486 ENSMUST00000019268.4
Scrn1
secernin 1
chr11_+_114851142 0.486 ENSMUST00000133245.1
ENSMUST00000122967.2
Gprc5c

G protein-coupled receptor, family C, group 5, member C

chr14_-_52104015 0.483 ENSMUST00000111610.4
ENSMUST00000164655.1
Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chrX_+_107255878 0.482 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
Gpr174


G protein-coupled receptor 174


chr4_+_95557494 0.477 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr1_-_161070613 0.475 ENSMUST00000035430.3
Dars2
aspartyl-tRNA synthetase 2 (mitochondrial)
chr1_+_78310295 0.455 ENSMUST00000036172.8
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr5_-_3647806 0.407 ENSMUST00000119783.1
ENSMUST00000007559.8
Gatad1

GATA zinc finger domain containing 1

chr4_+_103143052 0.388 ENSMUST00000106855.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr2_-_91649785 0.384 ENSMUST00000111333.1
Zfp408
zinc finger protein 408
chr7_+_19368498 0.374 ENSMUST00000132655.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr6_+_125552948 0.341 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr9_-_13818665 0.336 ENSMUST00000150893.1
ENSMUST00000124883.1
Cep57

centrosomal protein 57

chr3_+_19187321 0.300 ENSMUST00000130806.1
ENSMUST00000117529.1
ENSMUST00000119865.1
Mtfr1


mitochondrial fission regulator 1


chr2_+_76650264 0.269 ENSMUST00000099986.2
Dfnb59
deafness, autosomal recessive 59 (human)
chr4_+_154964117 0.254 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr3_+_88297147 0.250 ENSMUST00000164166.1
ENSMUST00000168062.1
Cct3

chaperonin containing Tcp1, subunit 3 (gamma)

chrM_+_8600 0.244 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr6_+_47920476 0.217 ENSMUST00000009411.8
Zfp212
Zinc finger protein 212
chr4_-_129227883 0.215 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr1_+_93421682 0.214 ENSMUST00000096427.4
Gm17415
predicted gene, 17415
chr3_+_88297115 0.200 ENSMUST00000001452.7
Cct3
chaperonin containing Tcp1, subunit 3 (gamma)
chr19_-_32196393 0.197 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr4_+_62525369 0.189 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr12_+_102128718 0.149 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr8_+_36489191 0.147 ENSMUST00000171777.1
6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr5_-_100416115 0.113 ENSMUST00000182886.1
ENSMUST00000094578.4
Sec31a

Sec31 homolog A (S. cerevisiae)

chr12_+_80644212 0.085 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr2_+_69897255 0.059 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr7_+_101896817 0.050 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr14_-_104522615 0.046 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr3_+_125404292 0.032 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr11_-_99230998 0.027 ENSMUST00000103133.3
Smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr9_+_72958785 0.002 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 31.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.9 8.7 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
2.4 7.2 GO:0097212 lysosomal membrane organization(GO:0097212)
2.3 9.1 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
2.2 6.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
1.8 5.5 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
1.7 5.0 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
1.5 4.6 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.2 3.5 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
1.2 8.1 GO:0019532 oxalate transport(GO:0019532)
1.1 5.7 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
1.0 3.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.7 12.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.6 2.5 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.6 4.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.5 2.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.4 3.8 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.4 2.0 GO:0015819 lysine transport(GO:0015819)
0.4 4.9 GO:0031017 exocrine pancreas development(GO:0031017)
0.3 1.0 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.3 1.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 0.8 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.3 0.8 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.2 6.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.6 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.2 0.8 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.2 0.6 GO:0010757 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) negative regulation of plasminogen activation(GO:0010757) regulation of vascular wound healing(GO:0061043) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 3.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 1.3 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 1.9 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.2 0.6 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 8.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 2.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.9 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.5 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 4.9 GO:0051693 actin filament capping(GO:0051693)
0.1 2.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 1.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 1.1 GO:0060134 prepulse inhibition(GO:0060134)
0.1 1.1 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.5 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 1.5 GO:0006907 pinocytosis(GO:0006907)
0.1 2.7 GO:0030901 midbrain development(GO:0030901)
0.1 4.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 4.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.9 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.4 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.5 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 1.1 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 0.7 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.4 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.8 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.1 GO:0097186 amelogenesis(GO:0097186)
0.0 0.5 GO:0043029 T cell homeostasis(GO:0043029)
0.0 1.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 31.4 GO:0043205 fibril(GO:0043205)
0.9 3.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.5 4.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.4 5.5 GO:0016600 flotillin complex(GO:0016600)
0.4 1.8 GO:0008623 CHRAC(GO:0008623)
0.1 4.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 3.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 8.7 GO:0016459 myosin complex(GO:0016459)
0.1 1.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 7.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 12.7 GO:0000792 heterochromatin(GO:0000792)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.7 GO:0034709 methylosome(GO:0034709)
0.0 1.0 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 8.9 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 9.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 5.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 0.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.5 GO:0070382 exocytic vesicle(GO:0070382)
0.0 2.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.1 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 1.4 GO:0030496 midbody(GO:0030496)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 3.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.4 GO:0043235 receptor complex(GO:0043235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 31.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.0 5.0 GO:0001849 complement component C1q binding(GO:0001849)
0.8 2.4 GO:0005118 sevenless binding(GO:0005118)
0.7 8.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.7 8.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.5 4.9 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.5 3.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 2.0 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.3 0.8 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.3 2.1 GO:0031432 titin binding(GO:0031432)
0.3 4.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.7 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.2 1.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 5.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 0.8 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 4.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 2.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 4.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.1 8.7 GO:0030507 spectrin binding(GO:0030507)
0.1 3.2 GO:0070410 co-SMAD binding(GO:0070410)
0.1 2.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 3.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 2.0 GO:0016594 glycine binding(GO:0016594)
0.1 0.9 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.6 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 3.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.9 GO:0005109 frizzled binding(GO:0005109)
0.1 3.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 3.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.9 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.1 20.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 1.1 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 0.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 6.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 5.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.5 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)
0.0 0.5 GO:0042556 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0022821 calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0017161 JUN kinase phosphatase activity(GO:0008579) phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 11.3 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.0 0.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)