Motif ID: Gtf2i_Gtf2f1

Z-value: 2.721

Transcription factors associated with Gtf2i_Gtf2f1:

Gene SymbolEntrez IDGene Name
Gtf2f1 ENSMUSG00000002658.9 Gtf2f1
Gtf2i ENSMUSG00000060261.9 Gtf2i

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gtf2f1mm10_v2_chr17_-_57011271_57011326-0.253.8e-02Click!
Gtf2imm10_v2_chr5_-_134314678_134314760-0.217.7e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gtf2i_Gtf2f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66948419 74.838 ENSMUST00000167817.1
Ndrg1
N-myc downstream regulated gene 1
chr7_+_44310213 47.276 ENSMUST00000107938.1
Shank1
SH3/ankyrin domain gene 1
chr14_-_55116935 45.950 ENSMUST00000022819.5
Jph4
junctophilin 4
chr1_-_56971762 42.169 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr16_-_74411292 33.936 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chrX_-_104201126 33.628 ENSMUST00000056502.6
ENSMUST00000118314.1
C77370

expressed sequence C77370

chr7_-_126949499 32.344 ENSMUST00000106339.1
ENSMUST00000052937.5
Asphd1

aspartate beta-hydroxylase domain containing 1

chr16_-_42340595 32.255 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr9_+_40686002 31.188 ENSMUST00000034522.7
Clmp
CXADR-like membrane protein
chr6_-_32588192 31.137 ENSMUST00000115096.2
Plxna4
plexin A4
chr7_-_78578308 30.906 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr2_+_136713444 30.292 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr13_+_42709482 30.258 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr16_-_74411776 28.729 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr5_-_44799643 28.523 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr1_-_72536930 27.957 ENSMUST00000047786.5
March4
membrane-associated ring finger (C3HC4) 4
chr6_-_77979652 27.914 ENSMUST00000161846.1
ENSMUST00000160894.1
Ctnna2

catenin (cadherin associated protein), alpha 2

chr12_+_105336922 27.821 ENSMUST00000180503.1
2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr2_+_37516618 27.710 ENSMUST00000065441.6
Gpr21
G protein-coupled receptor 21
chr8_+_112570043 27.490 ENSMUST00000034225.6
ENSMUST00000118171.1
Cntnap4

contactin associated protein-like 4


Gene overrepresentation in biological_process category:

Showing 1 to 20 of 619 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.3 117.1 GO:2000821 regulation of grooming behavior(GO:2000821)
5.1 81.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
26.4 79.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
6.3 75.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
7.5 74.8 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
5.7 68.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
10.6 63.7 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.8 58.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
3.8 56.8 GO:0071625 vocalization behavior(GO:0071625)
7.6 52.9 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
1.1 52.6 GO:0007019 microtubule depolymerization(GO:0007019)
1.1 50.4 GO:0008542 visual learning(GO:0008542)
4.0 48.5 GO:0016082 synaptic vesicle priming(GO:0016082)
0.7 48.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
15.6 46.8 GO:0046959 habituation(GO:0046959)
11.4 45.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
2.8 44.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
14.2 42.5 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
3.5 41.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
6.9 41.3 GO:0016198 axon choice point recognition(GO:0016198)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 230 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 250.2 GO:0060076 excitatory synapse(GO:0060076)
2.7 152.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 139.8 GO:0031224 intrinsic component of membrane(GO:0031224)
6.3 132.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.8 106.5 GO:0070382 exocytic vesicle(GO:0070382)
3.9 96.8 GO:0030673 axolemma(GO:0030673)
2.2 96.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
3.9 78.3 GO:0032279 asymmetric synapse(GO:0032279)
2.4 77.2 GO:0055038 recycling endosome membrane(GO:0055038)
15.2 75.9 GO:0030314 junctional membrane complex(GO:0030314)
4.1 69.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.8 61.6 GO:0043204 perikaryon(GO:0043204)
0.3 55.9 GO:0045202 synapse(GO:0045202)
0.5 52.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 48.1 GO:0005768 endosome(GO:0005768)
2.6 47.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.8 46.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
9.1 45.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.7 43.3 GO:0005905 clathrin-coated pit(GO:0005905)
10.7 43.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 373 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 143.1 GO:0045296 cadherin binding(GO:0045296)
1.0 139.1 GO:0017124 SH3 domain binding(GO:0017124)
0.4 127.4 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
8.8 79.3 GO:0008046 axon guidance receptor activity(GO:0008046)
3.3 78.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.7 67.0 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
7.6 60.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
10.0 59.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
3.3 58.9 GO:0050321 tau-protein kinase activity(GO:0050321)
7.8 54.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 53.6 GO:0015631 tubulin binding(GO:0015631)
1.1 52.1 GO:0045499 chemorepellent activity(GO:0045499)
1.5 51.6 GO:0070412 R-SMAD binding(GO:0070412)
12.6 50.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.9 50.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
1.3 48.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
2.6 47.7 GO:0016917 GABA receptor activity(GO:0016917)
3.4 47.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
4.7 46.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
7.6 45.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)