Motif ID: Hand1

Z-value: 1.339


Transcription factors associated with Hand1:

Gene SymbolEntrez IDGene Name
Hand1 ENSMUSG00000037335.7 Hand1



Activity profile for motif Hand1.

activity profile for motif Hand1


Sorted Z-values histogram for motif Hand1

Sorted Z-values for motif Hand1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hand1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_30445508 18.010 ENSMUST00000006828.7
Aplp1
amyloid beta (A4) precursor-like protein 1
chr19_-_59076069 14.527 ENSMUST00000047511.7
ENSMUST00000163821.1
4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr1_+_75507077 12.301 ENSMUST00000037330.4
Inha
inhibin alpha
chr15_+_81936911 12.024 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr8_+_84723003 10.942 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr4_-_20778527 10.608 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr4_-_138396438 10.429 ENSMUST00000105032.2
Fam43b
family with sequence similarity 43, member B
chr8_-_109251698 10.321 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr15_+_80097866 9.690 ENSMUST00000143928.1
Syngr1
synaptogyrin 1
chr15_+_92051153 9.417 ENSMUST00000169825.1
Cntn1
contactin 1
chr19_-_4698315 9.352 ENSMUST00000096325.3
Gm960
predicted gene 960
chr15_+_82274935 9.068 ENSMUST00000023095.6
Sept3
septin 3
chr1_-_176807124 9.036 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr2_+_118663235 8.985 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr14_+_27622433 8.916 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr2_-_168741752 8.134 ENSMUST00000029060.4
Atp9a
ATPase, class II, type 9A
chr4_+_101550411 7.832 ENSMUST00000094953.4
ENSMUST00000106933.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr11_+_57011945 7.767 ENSMUST00000094179.4
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr7_+_126950518 7.767 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr17_-_81649607 7.652 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr16_+_31422268 7.640 ENSMUST00000089759.2
Bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr11_-_42000284 7.569 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr11_+_32000496 7.515 ENSMUST00000093219.3
Nsg2
neuron specific gene family member 2
chr18_+_37400845 7.449 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr12_+_73997749 7.448 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr15_+_81936753 7.247 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr7_+_126950687 7.239 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr11_+_57011798 7.190 ENSMUST00000036315.9
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr18_+_37484955 7.189 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr5_+_19907502 7.147 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_-_37049203 7.125 ENSMUST00000037491.8
F13a1
coagulation factor XIII, A1 subunit
chr5_+_66968416 7.103 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr5_+_81021202 7.049 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr11_-_81968415 6.941 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr14_-_73385225 6.871 ENSMUST00000022704.7
Itm2b
integral membrane protein 2B
chr19_+_4855129 6.836 ENSMUST00000119694.1
Ctsf
cathepsin F
chr4_-_42034726 6.662 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr12_+_105453831 6.550 ENSMUST00000178224.1
D430019H16Rik
RIKEN cDNA D430019H16 gene
chr6_-_41636389 6.384 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr15_-_81697256 6.363 ENSMUST00000072910.5
Chadl
chondroadherin-like
chr9_-_20879718 6.280 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr16_+_38089001 6.260 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr10_-_29144194 6.230 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr13_-_34077992 6.128 ENSMUST00000056427.8
Tubb2a
tubulin, beta 2A class IIA
chr13_-_92131494 6.096 ENSMUST00000099326.3
ENSMUST00000146492.1
Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr4_+_102760294 5.941 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1



chr2_+_155940728 5.908 ENSMUST00000109629.1
Gm15557
predicted gene 15557
chr5_+_66968559 5.714 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr10_+_29143996 5.693 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr15_-_58214882 5.663 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr17_+_3532554 5.656 ENSMUST00000168560.1
Cldn20
claudin 20
chr18_+_37435602 5.636 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12
chr2_+_178141920 5.630 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr7_-_47133684 5.620 ENSMUST00000102626.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr11_+_3330781 5.617 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr19_-_42086338 5.614 ENSMUST00000051772.8
Morn4
MORN repeat containing 4
chr19_-_4698668 5.462 ENSMUST00000177696.1
Gm960
predicted gene 960
chr18_-_31317043 5.429 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chrX_-_95166307 5.388 ENSMUST00000113873.2
ENSMUST00000113876.2
ENSMUST00000113885.1
ENSMUST00000113883.1
ENSMUST00000182001.1
ENSMUST00000113882.1
ENSMUST00000113878.1
ENSMUST00000182562.1
Arhgef9







CDC42 guanine nucleotide exchange factor (GEF) 9







chr7_-_47133395 5.316 ENSMUST00000107617.1
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr5_+_19907774 5.300 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_66968961 5.282 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr11_+_101246960 5.265 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr4_+_102760135 5.216 ENSMUST00000066824.7
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr13_+_29014399 5.088 ENSMUST00000146336.1
ENSMUST00000130109.1
A330102I10Rik

RIKEN cDNA A330102I10 gene

chr5_-_84417359 5.067 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr4_-_141598206 5.046 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr16_-_45158650 5.026 ENSMUST00000023344.3
Slc35a5
solute carrier family 35, member A5
chr15_+_82275197 4.946 ENSMUST00000116423.1
Sept3
septin 3
chr11_-_102296618 4.860 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr9_+_58823512 4.793 ENSMUST00000034889.8
Hcn4
hyperpolarization-activated, cyclic nucleotide-gated K+ 4
chr13_+_37345338 4.754 ENSMUST00000021860.5
Ly86
lymphocyte antigen 86
chr19_-_5098418 4.728 ENSMUST00000025805.6
Cnih2
cornichon homolog 2 (Drosophila)
chr9_+_53771499 4.662 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr11_+_78188737 4.603 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr7_-_27553138 4.596 ENSMUST00000127240.1
ENSMUST00000117095.1
ENSMUST00000117611.1
Pld3


phospholipase D family, member 3


chr13_+_83738874 4.491 ENSMUST00000052354.4
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr7_+_47050628 4.461 ENSMUST00000010451.5
Tmem86a
transmembrane protein 86A
chr16_-_34095983 4.455 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr11_-_95041335 4.447 ENSMUST00000038431.7
Pdk2
pyruvate dehydrogenase kinase, isoenzyme 2
chr11_+_77930800 4.430 ENSMUST00000093995.3
ENSMUST00000000646.7
Sez6

seizure related gene 6

chr11_-_106613370 4.409 ENSMUST00000128933.1
Tex2
testis expressed gene 2
chr15_-_71727815 4.385 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr7_+_18884679 4.378 ENSMUST00000032573.6
Pglyrp1
peptidoglycan recognition protein 1
chr14_-_26971232 4.373 ENSMUST00000036570.4
Appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr4_+_126609818 4.369 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr15_-_75905349 4.352 ENSMUST00000127550.1
Eef1d
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr12_+_112588753 4.347 ENSMUST00000101029.2
Inf2
inverted formin, FH2 and WH2 domain containing
chr4_-_45084538 4.326 ENSMUST00000052236.6
Fbxo10
F-box protein 10
chr4_-_118180043 4.316 ENSMUST00000106406.2
Kdm4a
lysine (K)-specific demethylase 4A
chr1_-_37865040 4.272 ENSMUST00000041815.8
Tsga10
testis specific 10
chr9_-_101251810 4.231 ENSMUST00000075941.5
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr12_-_72070991 4.209 ENSMUST00000050649.4
Gpr135
G protein-coupled receptor 135
chr4_-_118179946 4.169 ENSMUST00000050288.8
ENSMUST00000106403.1
Kdm4a

lysine (K)-specific demethylase 4A

chr2_-_32381909 4.118 ENSMUST00000048792.4
1110008P14Rik
RIKEN cDNA 1110008P14 gene
chr2_+_149830840 4.116 ENSMUST00000109934.1
ENSMUST00000140870.1
Syndig1

synapse differentiation inducing 1

chr4_-_151108454 4.070 ENSMUST00000105670.1
Camta1
calmodulin binding transcription activator 1
chr5_-_38220400 4.048 ENSMUST00000114113.1
ENSMUST00000094833.3
Zbtb49

zinc finger and BTB domain containing 49

chr2_+_149830894 3.877 ENSMUST00000137280.1
ENSMUST00000149705.1
Syndig1

synapse differentiation inducing 1

chr4_-_117883428 3.863 ENSMUST00000030266.5
B4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr4_-_117887292 3.804 ENSMUST00000150204.1
ENSMUST00000147845.1
ENSMUST00000036380.7
ENSMUST00000136596.1
Atp6v0b



ATPase, H+ transporting, lysosomal V0 subunit B



chr5_+_138171997 3.788 ENSMUST00000019662.4
ENSMUST00000151318.1
Ap4m1

adaptor-related protein complex AP-4, mu 1

chr11_+_4135233 3.752 ENSMUST00000124670.1
Rnf215
ring finger protein 215
chr2_+_30392405 3.706 ENSMUST00000113612.3
ENSMUST00000123202.1
Dolpp1

dolichyl pyrophosphate phosphatase 1

chr4_-_117887279 3.680 ENSMUST00000132073.1
Atp6v0b
ATPase, H+ transporting, lysosomal V0 subunit B
chr18_+_37411674 3.652 ENSMUST00000051126.2
Pcdhb10
protocadherin beta 10
chr3_+_86084434 3.634 ENSMUST00000107664.2
Sh3d19
SH3 domain protein D19
chr3_+_65109343 3.633 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr7_+_28693032 3.632 ENSMUST00000151227.1
ENSMUST00000108281.1
Fbxo27

F-box protein 27

chr17_+_21491256 3.621 ENSMUST00000076664.6
Zfp53
zinc finger protein 53
chr16_+_4036942 3.597 ENSMUST00000137748.1
ENSMUST00000006136.4
ENSMUST00000157044.1
ENSMUST00000120009.1
Dnase1



deoxyribonuclease I



chr13_+_105443693 3.571 ENSMUST00000022235.4
Htr1a
5-hydroxytryptamine (serotonin) receptor 1A
chrX_+_56609751 3.531 ENSMUST00000144068.1
Slc9a6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr17_-_47692466 3.450 ENSMUST00000113300.1
Prickle4
prickle homolog 4 (Drosophila)
chr15_+_60822947 3.434 ENSMUST00000180730.1
9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr6_+_17491216 3.391 ENSMUST00000080469.5
Met
met proto-oncogene
chrX_+_56609843 3.371 ENSMUST00000077741.5
ENSMUST00000114784.2
Slc9a6

solute carrier family 9 (sodium/hydrogen exchanger), member 6

chr7_-_100964371 3.366 ENSMUST00000060174.4
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_-_109298121 3.300 ENSMUST00000020920.3
Rgs9
regulator of G-protein signaling 9
chr8_+_93810832 3.236 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr7_-_4725082 3.235 ENSMUST00000086363.4
ENSMUST00000086364.4
Tmem150b

transmembrane protein 150B

chr10_+_58255465 3.226 ENSMUST00000057659.7
ENSMUST00000162041.1
ENSMUST00000162860.1
Gcc2


GRIP and coiled-coil domain containing 2


chr6_+_39573894 3.200 ENSMUST00000051249.6
Adck2
aarF domain containing kinase 2
chr7_-_45366714 3.198 ENSMUST00000107779.1
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr4_-_118179628 3.197 ENSMUST00000097911.2
Kdm4a
lysine (K)-specific demethylase 4A
chr9_+_111439063 3.150 ENSMUST00000111879.3
Dclk3
doublecortin-like kinase 3
chr15_+_98092569 3.137 ENSMUST00000163507.1
Pfkm
phosphofructokinase, muscle
chrX_+_153237466 3.129 ENSMUST00000143880.1
Klf8
Kruppel-like factor 8
chr7_+_5051515 3.114 ENSMUST00000069324.5
Zfp580
zinc finger protein 580
chr9_-_122862128 3.114 ENSMUST00000056467.7
Zfp445
zinc finger protein 445
chr2_+_96318014 3.100 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr12_-_76822510 3.089 ENSMUST00000021459.7
Rab15
RAB15, member RAS oncogene family
chr11_-_96916366 3.077 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr2_-_27027909 3.065 ENSMUST00000102890.4
ENSMUST00000153388.1
ENSMUST00000045702.5
Slc2a6


solute carrier family 2 (facilitated glucose transporter), member 6


chr11_-_118569910 3.000 ENSMUST00000136551.1
Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr4_-_127313980 2.993 ENSMUST00000053753.7
Gja4
gap junction protein, alpha 4
chr19_+_8837676 2.978 ENSMUST00000159634.1
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr11_+_72689997 2.950 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr5_-_142509653 2.949 ENSMUST00000110784.1
Radil
Ras association and DIL domains
chr11_-_106612928 2.926 ENSMUST00000042780.7
Tex2
testis expressed gene 2
chr3_+_96576984 2.923 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr9_-_50739365 2.894 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr11_+_82035569 2.856 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr4_-_4138817 2.789 ENSMUST00000133567.1
Penk
preproenkephalin
chr15_-_89477400 2.771 ENSMUST00000165199.1
Arsa
arylsulfatase A
chr14_+_51893610 2.761 ENSMUST00000047726.5
ENSMUST00000161888.1
Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr5_-_71658308 2.744 ENSMUST00000031121.5
Gabra4
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr10_+_97479470 2.698 ENSMUST00000105287.3
Dcn
decorin
chr7_-_19861299 2.693 ENSMUST00000014830.7
Ceacam16
carcinoembryonic antigen-related cell adhesion molecule 16
chr10_-_118868903 2.687 ENSMUST00000004281.8
Dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr11_+_70459940 2.669 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr4_-_155010984 2.652 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
Plch2


phospholipase C, eta 2


chr1_-_79761752 2.596 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
Wdfy1






WD repeat and FYVE domain containing 1






chr2_+_37443273 2.593 ENSMUST00000133434.1
ENSMUST00000061179.5
Rabgap1

RAB GTPase activating protein 1

chr10_+_82138253 2.585 ENSMUST00000105314.2
AU041133
expressed sequence AU041133
chr18_+_24709436 2.578 ENSMUST00000037097.7
Fhod3
formin homology 2 domain containing 3
chr19_-_5845471 2.544 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr6_+_125552948 2.536 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr8_+_20567716 2.482 ENSMUST00000178995.1
Gm21092
predicted gene, 21092
chr9_-_51077064 2.467 ENSMUST00000098782.3
Layn
layilin
chr18_+_37333853 2.460 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr8_-_25597459 2.445 ENSMUST00000079160.6
Letm2
leucine zipper-EF-hand containing transmembrane protein 2
chr6_+_127453667 2.429 ENSMUST00000112193.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chrX_+_10485121 2.405 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr19_+_8837445 2.387 ENSMUST00000171649.1
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr11_+_78188806 2.384 ENSMUST00000056241.5
Rab34
RAB34, member of RAS oncogene family
chr17_-_45686899 2.384 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr2_-_173276144 2.359 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr7_+_81858993 2.356 ENSMUST00000041890.1
Tm6sf1
transmembrane 6 superfamily member 1
chr1_-_39478734 2.353 ENSMUST00000054462.5
Tbc1d8
TBC1 domain family, member 8
chr15_-_79285502 2.344 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr1_-_54194048 2.307 ENSMUST00000120904.1
Hecw2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr4_+_136357423 2.305 ENSMUST00000182167.1
Gm17388
predicted gene, 17388
chr2_+_85136355 2.295 ENSMUST00000057019.7
Aplnr
apelin receptor
chr2_-_34826187 2.285 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2


F-box and WD-40 domain protein 2


chr3_+_88685785 2.279 ENSMUST00000029696.6
2810403A07Rik
RIKEN cDNA 2810403A07 gene
chr4_+_130913120 2.271 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr6_+_127453705 2.270 ENSMUST00000039680.5
Parp11
poly (ADP-ribose) polymerase family, member 11
chr12_+_65075582 2.268 ENSMUST00000058889.4
Fancm
Fanconi anemia, complementation group M
chr13_+_31806627 2.267 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr17_-_27623441 2.257 ENSMUST00000025050.5
Nudt3
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr7_-_141437587 2.227 ENSMUST00000172654.1
ENSMUST00000106006.1
Slc25a22

solute carrier family 25 (mitochondrial carrier, glutamate), member 22

chr5_+_71699918 2.225 ENSMUST00000031122.7
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr6_+_126939957 2.194 ENSMUST00000032497.3
D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chr7_+_29238434 2.162 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr2_+_29827342 2.108 ENSMUST00000091142.3
Urm1
ubiquitin related modifier 1 homolog (S. cerevisiae)
chr17_-_27623263 2.107 ENSMUST00000062397.6
ENSMUST00000176876.1
Nudt3

nudix (nucleotide diphosphate linked moiety X)-type motif 3

chr13_-_49147931 2.104 ENSMUST00000162581.1
ENSMUST00000110097.2
ENSMUST00000049265.8
ENSMUST00000035538.6
ENSMUST00000110096.1
ENSMUST00000091623.3
Wnk2





WNK lysine deficient protein kinase 2





chr7_+_81523555 2.066 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr11_+_78188422 2.042 ENSMUST00000002128.7
ENSMUST00000150941.1
Rab34

RAB34, member of RAS oncogene family

chr4_-_129623870 2.034 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
Ccdc28b


coiled coil domain containing 28B


chr2_-_34826071 2.015 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr3_+_107101551 2.011 ENSMUST00000038695.1
Kcna2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr8_+_125734203 2.008 ENSMUST00000034313.6
ENSMUST00000065135.5
Ntpcr

nucleoside-triphosphatase, cancer-related

chr11_-_109298090 1.967 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr4_-_20778852 1.960 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr18_+_77938452 1.936 ENSMUST00000044622.5
Epg5
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr4_+_130913264 1.910 ENSMUST00000156225.1
ENSMUST00000156742.1
Laptm5

lysosomal-associated protein transmembrane 5

chr4_-_155043143 1.878 ENSMUST00000135665.2
Plch2
phospholipase C, eta 2
chr1_-_75191923 1.873 ENSMUST00000040689.8
Atg9a
autophagy related 9A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 18.0 GO:0071873 response to norepinephrine(GO:0071873)
4.9 14.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
2.3 6.9 GO:0050915 sensory perception of sour taste(GO:0050915)
2.2 10.9 GO:2001025 positive regulation of response to drug(GO:2001025)
2.1 6.4 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
2.1 6.3 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
2.1 12.3 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
1.9 5.7 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
1.8 14.6 GO:0097369 sodium ion import(GO:0097369)
1.7 22.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
1.6 7.8 GO:0072318 clathrin coat disassembly(GO:0072318)
1.5 4.4 GO:0071544 diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544)
1.4 2.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.4 4.2 GO:0007525 somatic muscle development(GO:0007525)
1.4 2.7 GO:2001023 regulation of response to drug(GO:2001023)
1.2 7.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
1.2 3.6 GO:0031117 serotonin receptor signaling pathway(GO:0007210) positive regulation of microtubule depolymerization(GO:0031117)
1.2 11.7 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.1 3.4 GO:0030321 transepithelial chloride transport(GO:0030321)
1.1 4.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
1.1 9.8 GO:0071420 cellular response to histamine(GO:0071420)
1.0 4.8 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.9 4.7 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.9 3.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.9 9.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.9 2.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.8 13.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.8 5.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.8 2.3 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.7 2.9 GO:0032439 endosome localization(GO:0032439)
0.7 6.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.7 4.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.7 17.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.6 2.6 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.6 5.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.6 1.8 GO:0042938 dipeptide transport(GO:0042938)
0.6 1.2 GO:1900426 positive regulation of defense response to bacterium(GO:1900426)
0.6 4.8 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.6 3.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.6 2.8 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.6 4.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.6 1.7 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.5 1.6 GO:0060023 soft palate development(GO:0060023)
0.5 3.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.5 6.4 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.5 3.1 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glycolytic process through glucose-1-phosphate(GO:0061622) glucose catabolic process to pyruvate(GO:0061718)
0.5 3.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.5 15.0 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.5 6.9 GO:0018149 peptide cross-linking(GO:0018149)
0.5 2.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.5 3.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.5 1.9 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.4 1.7 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.4 1.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.4 2.9 GO:0033227 dsRNA transport(GO:0033227)
0.4 11.2 GO:0097320 membrane tubulation(GO:0097320)
0.4 5.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.4 6.1 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.4 2.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.3 1.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 3.1 GO:0071569 protein ufmylation(GO:0071569)
0.3 7.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 2.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.3 3.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.3 0.6 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.3 4.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.3 5.7 GO:0007035 vacuolar acidification(GO:0007035)
0.3 0.9 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 1.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.3 2.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 0.9 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.3 2.6 GO:0051639 actin filament network formation(GO:0051639)
0.3 5.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.3 0.8 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.3 24.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.3 2.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 0.9 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.2 0.6 GO:0018094 protein polyglycylation(GO:0018094)
0.2 2.3 GO:0051764 actin crosslink formation(GO:0051764)
0.2 8.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 3.7 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 1.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 1.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 0.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 0.9 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 1.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 3.6 GO:0006308 DNA catabolic process(GO:0006308)
0.2 0.7 GO:0006788 heme oxidation(GO:0006788)
0.2 4.9 GO:0016578 histone deubiquitination(GO:0016578)
0.2 4.4 GO:0009299 mRNA transcription(GO:0009299)
0.2 1.4 GO:0030035 microspike assembly(GO:0030035)
0.1 1.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 1.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.5 GO:0097709 columnar/cuboidal epithelial cell maturation(GO:0002069) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) connective tissue replacement(GO:0097709)
0.1 1.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 3.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.2 GO:0042989 sequestering of actin monomers(GO:0042989) actin filament severing(GO:0051014)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 13.6 GO:0007613 memory(GO:0007613)
0.1 0.3 GO:0043312 neutrophil degranulation(GO:0043312)
0.1 1.8 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.1 0.5 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 2.3 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1 1.9 GO:0097352 autophagosome maturation(GO:0097352)
0.1 4.2 GO:0043113 receptor clustering(GO:0043113)
0.1 1.9 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.1 0.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 2.5 GO:0043954 cellular component maintenance(GO:0043954)
0.1 2.2 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 4.4 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.1 0.3 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 2.8 GO:0006829 zinc II ion transport(GO:0006829)
0.1 1.1 GO:0001504 neurotransmitter uptake(GO:0001504)
0.1 4.7 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 1.2 GO:0003094 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.1 0.4 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 2.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 4.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.5 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 1.5 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 1.2 GO:0015813 L-glutamate transport(GO:0015813)
0.1 1.3 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 4.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.6 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 1.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 7.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 1.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.0 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.7 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.5 GO:0015908 fatty acid transport(GO:0015908)
0.0 2.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 3.8 GO:0010506 regulation of autophagy(GO:0010506)
0.0 3.3 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.4 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 2.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0051905 pigment granule transport(GO:0051904) establishment of pigment granule localization(GO:0051905)
0.0 12.3 GO:0006397 mRNA processing(GO:0006397)
0.0 5.5 GO:0006887 exocytosis(GO:0006887)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.2 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 3.2 GO:0007568 aging(GO:0007568)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.1 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799) negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.5 GO:0030317 sperm motility(GO:0030317)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
3.6 21.9 GO:0044308 axonal spine(GO:0044308)
2.5 12.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.4 14.6 GO:1990635 proximal dendrite(GO:1990635)
1.5 4.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
1.1 7.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.0 2.9 GO:0044299 C-fiber(GO:0044299)
0.9 11.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.8 3.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.8 2.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.7 4.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.7 2.8 GO:0032280 symmetric synapse(GO:0032280)
0.7 12.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.6 6.3 GO:1990909 Wnt signalosome(GO:1990909)
0.5 2.7 GO:0032426 stereocilium tip(GO:0032426)
0.5 2.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.4 1.3 GO:0097443 sorting endosome(GO:0097443)
0.4 1.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 11.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.4 1.8 GO:0036449 microtubule minus-end(GO:0036449)
0.3 2.5 GO:0042382 paraspeckles(GO:0042382)
0.3 28.2 GO:0043198 dendritic shaft(GO:0043198)
0.3 23.0 GO:0042734 presynaptic membrane(GO:0042734)
0.3 3.6 GO:0043203 axon hillock(GO:0043203)
0.3 1.0 GO:1990130 Iml1 complex(GO:1990130)
0.3 2.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 3.0 GO:0000124 SAGA complex(GO:0000124)
0.2 1.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 10.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 2.3 GO:0071439 clathrin complex(GO:0071439)
0.2 4.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 6.9 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 10.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 12.2 GO:0031985 Golgi cisterna(GO:0031985)
0.2 3.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 5.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 11.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 3.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 3.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 8.7 GO:0072562 blood microparticle(GO:0072562)
0.1 9.0 GO:0005814 centriole(GO:0005814)
0.1 3.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.3 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 4.4 GO:0098794 postsynapse(GO:0098794)
0.1 5.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 1.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.6 GO:0031091 platelet alpha granule(GO:0031091)
0.1 4.8 GO:0043195 terminal bouton(GO:0043195)
0.1 1.2 GO:0005922 connexon complex(GO:0005922)
0.1 2.4 GO:0031901 early endosome membrane(GO:0031901)
0.1 8.1 GO:0055037 recycling endosome(GO:0055037)
0.1 1.4 GO:0030175 filopodium(GO:0030175)
0.1 8.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 7.7 GO:0031514 motile cilium(GO:0031514)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.2 GO:0030904 retromer complex(GO:0030904)
0.1 4.7 GO:0005643 nuclear pore(GO:0005643)
0.1 5.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 2.9 GO:0043679 axon terminus(GO:0043679)
0.1 6.2 GO:0043197 dendritic spine(GO:0043197)
0.0 2.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 6.9 GO:0043209 myelin sheath(GO:0043209)
0.0 3.0 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 2.6 GO:0005769 early endosome(GO:0005769)
0.0 3.1 GO:0005938 cell cortex(GO:0005938)
0.0 1.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 3.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.1 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 3.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 4.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 18.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
2.5 7.6 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
2.5 14.8 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
2.1 15.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.1 12.4 GO:0070699 type II activin receptor binding(GO:0070699)
1.9 7.7 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
1.9 5.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.8 7.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.8 12.3 GO:0034711 inhibin binding(GO:0034711)
1.4 5.6 GO:0042834 peptidoglycan binding(GO:0042834)
1.3 7.5 GO:0032051 clathrin light chain binding(GO:0032051)
1.1 2.3 GO:0008301 DNA binding, bending(GO:0008301)
1.1 4.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.0 4.8 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.9 3.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.9 6.9 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.8 3.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.8 3.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.8 3.9 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.7 4.4 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.7 2.9 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7 2.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.7 12.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.7 11.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.6 5.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.6 7.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.6 4.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.5 3.2 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5 1.5 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.5 10.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.5 3.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.5 2.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.4 2.8 GO:0001515 opioid peptide activity(GO:0001515)
0.4 9.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 8.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 1.8 GO:0042895 antibiotic transporter activity(GO:0042895)
0.4 6.9 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 3.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.4 6.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.4 5.3 GO:0015026 coreceptor activity(GO:0015026)
0.3 1.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.3 1.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 5.6 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.3 5.0 GO:0031005 filamin binding(GO:0031005)
0.3 0.9 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 1.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 0.9 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.3 0.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 2.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 4.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 4.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 3.2 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.2 0.9 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 4.9 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 2.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.2 5.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 3.6 GO:0070402 NADPH binding(GO:0070402)
0.2 1.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 1.7 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 3.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 7.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 2.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 0.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 2.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.4 GO:0047499 lysophospholipase activity(GO:0004622) calcium-independent phospholipase A2 activity(GO:0047499)
0.2 1.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 3.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 3.6 GO:0070064 proline-rich region binding(GO:0070064)
0.2 3.6 GO:0043422 protein kinase B binding(GO:0043422)
0.2 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 0.9 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 4.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 9.4 GO:0030276 clathrin binding(GO:0030276)
0.1 0.6 GO:0080084 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.1 1.5 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) very long-chain fatty acid-CoA ligase activity(GO:0031957) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.1 1.5 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 4.5 GO:0005518 collagen binding(GO:0005518)
0.1 2.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 13.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.1 2.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 15.2 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 9.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 6.4 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 1.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 11.3 GO:0001948 glycoprotein binding(GO:0001948)
0.1 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 4.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.4 GO:0050699 WW domain binding(GO:0050699)
0.1 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.4 GO:0070628 proteasome binding(GO:0070628)
0.1 0.8 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 4.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 4.2 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.4 GO:0008198 ferrous iron binding(GO:0008198)
0.0 3.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 8.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 2.0 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.7 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 3.0 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 1.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 3.2 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 1.2 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.6 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) sterol O-acyltransferase activity(GO:0004772) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 1.2 GO:0019843 rRNA binding(GO:0019843)
0.0 4.2 GO:0051020 GTPase binding(GO:0051020)
0.0 0.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.0 0.6 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)