Motif ID: Hand1

Z-value: 1.339


Transcription factors associated with Hand1:

Gene SymbolEntrez IDGene Name
Hand1 ENSMUSG00000037335.7 Hand1



Activity profile for motif Hand1.

activity profile for motif Hand1


Sorted Z-values histogram for motif Hand1

Sorted Z-values for motif Hand1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hand1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_30445508 18.010 ENSMUST00000006828.7
 Aplp1
amyloid beta (A4) precursor-like protein 1
chr19_-_59076069 14.527 ENSMUST00000047511.7
ENSMUST00000163821.1
 4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr1_+_75507077 12.301 ENSMUST00000037330.4
 Inha
inhibin alpha
chr15_+_81936911 12.024 ENSMUST00000135663.1
 Csdc2
cold shock domain containing C2, RNA binding
chr8_+_84723003 10.942 ENSMUST00000098571.4
 G430095P16Rik
RIKEN cDNA G430095P16 gene
chr4_-_20778527 10.608 ENSMUST00000119374.1
 Nkain3
Na+/K+ transporting ATPase interacting 3
chr4_-_138396438 10.429 ENSMUST00000105032.2
 Fam43b
family with sequence similarity 43, member B
chr8_-_109251698 10.321 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr15_+_80097866 9.690 ENSMUST00000143928.1
 Syngr1
synaptogyrin 1
chr15_+_92051153 9.417 ENSMUST00000169825.1
 Cntn1
contactin 1
chr19_-_4698315 9.352 ENSMUST00000096325.3
 Gm960
predicted gene 960
chr15_+_82274935 9.068 ENSMUST00000023095.6
 Sept3
septin 3
chr1_-_176807124 9.036 ENSMUST00000057037.7
 Cep170
centrosomal protein 170
chr2_+_118663235 8.985 ENSMUST00000099557.3
 Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr14_+_27622433 8.916 ENSMUST00000090302.5
 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr2_-_168741752 8.134 ENSMUST00000029060.4
 Atp9a
ATPase, class II, type 9A
chr4_+_101550411 7.832 ENSMUST00000094953.4
ENSMUST00000106933.1
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr11_+_57011945 7.767 ENSMUST00000094179.4
 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr7_+_126950518 7.767 ENSMUST00000106335.1
ENSMUST00000146017.1
 Sez6l2

seizure related 6 homolog like 2

chr17_-_81649607 7.652 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
 Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 24.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
1.7 22.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
6.0 18.0 GO:0071873 response to norepinephrine(GO:0071873)
0.7 17.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.5 15.0 GO:0045838 positive regulation of membrane potential(GO:0045838)
4.9 14.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
1.8 14.6 GO:0097369 sodium ion import(GO:0097369)
0.8 13.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 13.6 GO:0007613 memory(GO:0007613)
2.1 12.3 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.0 12.3 GO:0006397 mRNA processing(GO:0006397)
1.2 11.7 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.4 11.2 GO:0097320 membrane tubulation(GO:0097320)
2.2 10.9 GO:2001025 positive regulation of response to drug(GO:2001025)
1.1 9.8 GO:0071420 cellular response to histamine(GO:0071420)
0.9 9.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 8.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.6 7.8 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 7.5 GO:0048268 clathrin coat assembly(GO:0048268)
1.2 7.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 91 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 28.2 GO:0043198 dendritic shaft(GO:0043198)
0.3 23.0 GO:0042734 presynaptic membrane(GO:0042734)
3.6 21.9 GO:0044308 axonal spine(GO:0044308)
2.4 14.6 GO:1990635 proximal dendrite(GO:1990635)
0.7 12.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
2.5 12.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
4.1 12.3 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.2 12.2 GO:0031985 Golgi cisterna(GO:0031985)
0.4 11.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.9 11.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 11.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 10.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 10.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 9.0 GO:0005814 centriole(GO:0005814)
0.1 8.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 8.7 GO:0072562 blood microparticle(GO:0072562)
0.1 8.1 GO:0055037 recycling endosome(GO:0055037)
0.1 7.7 GO:0031514 motile cilium(GO:0031514)
1.1 7.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 6.9 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 132 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.5 18.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 15.2 GO:0017124 SH3 domain binding(GO:0017124)
2.1 15.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.5 14.8 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 13.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.7 12.5 GO:0004890 GABA-A receptor activity(GO:0004890)
2.1 12.4 GO:0070699 type II activin receptor binding(GO:0070699)
1.8 12.3 GO:0034711 inhibin binding(GO:0034711)
0.7 11.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 11.3 GO:0001948 glycoprotein binding(GO:0001948)
0.5 10.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 9.4 GO:0030276 clathrin binding(GO:0030276)
0.4 9.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 9.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 8.3 GO:0005516 calmodulin binding(GO:0005516)
0.4 8.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
1.9 7.7 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
2.5 7.6 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.3 7.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.6 7.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)