Motif ID: Hdx

Z-value: 5.267


Transcription factors associated with Hdx:

Gene SymbolEntrez IDGene Name
Hdx ENSMUSG00000034551.6 Hdx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hdxmm10_v2_chrX_-_111697069_111697127-0.104.0e-01Click!


Activity profile for motif Hdx.

activity profile for motif Hdx


Sorted Z-values histogram for motif Hdx

Sorted Z-values for motif Hdx



Network of associatons between targets according to the STRING database.



First level regulatory network of Hdx

PNG image of the network

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Top targets:


Showing 1 to 20 of 93 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3017408 338.651 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3015654 285.634 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr9_+_3023547 281.721 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3005125 249.708 ENSMUST00000179881.1
 Gm11168
predicted gene 11168
chr9_+_3000922 240.145 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chr9_+_3027439 232.898 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3034599 231.900 ENSMUST00000178641.1
 Gm17535
predicted gene, 17535
chr9_+_3025417 202.926 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr14_-_19418930 191.263 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3018753 165.273 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr9_+_3004457 152.777 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3036877 148.110 ENSMUST00000155807.2
 Gm10715
predicted gene 10715
chr9_+_3037111 138.173 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3013140 132.236 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr2_-_98667264 100.735 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr6_-_23248264 52.783 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr3_-_154330543 21.060 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr16_-_26989974 14.989 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr13_+_24327415 14.238 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr6_+_30568367 13.426 ENSMUST00000049251.5
 Cpa4
carboxypeptidase A4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1980.6 GO:0008150 biological_process(GO:0008150)
8.8 52.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 21.1 GO:0021884 forebrain neuron development(GO:0021884)
0.5 15.0 GO:0006270 DNA replication initiation(GO:0006270)
4.9 14.8 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
4.7 14.2 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
1.8 9.0 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
1.6 7.9 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
1.8 7.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.9 6.5 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 6.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.3 5.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 4.6 GO:0097352 autophagosome maturation(GO:0097352)
0.9 4.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) prolactin signaling pathway(GO:0038161)
0.6 4.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 3.0 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.2 2.8 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
1.2 2.4 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.6 2.3 GO:0006547 histidine metabolic process(GO:0006547)
0.1 2.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2067.0 GO:0005575 cellular_component(GO:0005575)
3.5 21.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.9 14.8 GO:0042101 T cell receptor complex(GO:0042101)
0.2 11.0 GO:0005876 spindle microtubule(GO:0005876)
0.6 9.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 6.5 GO:0071564 npBAF complex(GO:0071564)
1.0 5.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
1.2 4.7 GO:0032021 NELF complex(GO:0032021)
0.4 4.1 GO:0001739 sex chromatin(GO:0001739)
0.2 2.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 2.2 GO:0031105 septin complex(GO:0031105)
0.2 1.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 1.7 GO:0005638 lamin filament(GO:0005638)
0.4 1.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2038.4 GO:0003674 molecular_function(GO:0003674)
0.2 36.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
4.9 14.8 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
4.7 14.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.6 11.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.5 9.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
2.3 9.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.7 7.9 GO:0003680 AT DNA binding(GO:0003680)
2.4 7.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.7 5.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.5 4.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 4.5 GO:0017046 peptide hormone binding(GO:0017046)
0.2 2.8 GO:0070403 NAD+ binding(GO:0070403)
0.3 2.7 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.6 1.9 GO:0043532 angiostatin binding(GO:0043532)
0.3 1.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 1.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.1 GO:0008097 5S rRNA binding(GO:0008097)
0.2 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)